Despite tensions between Tillich's category of belief-ful realism and a view of science that embraces metaphysical and epistemological realism, a constructive relationship can be developed between the two. Both are based on common understandings about reality. Belief-ful or theonomous realism, thus, affirms scientific realism. On the other hand, scientific realism is open to the ecstatic, self-transcending elements of belief-ful realism. Finally, Tillich's formulation of the relationship between culture and religion can be reformulated specifically to include scientific and technological culture.