Antibiotic development and usage, and antibiotic resistance in particular, are today considered global concerns, simultaneously mandating local and global perspectives and actions. Yet such global considerations have not always been part of antibiotic policy formation, and those who attempt to formulate a globally coordinated response to antibiotic resistance will need to confront a history of heterogeneous, often uncoordinated, and at times conflicting reform efforts, whose legacies remain apparent today. Historical analysis permits us to highlight such entrenched trends and processes, helping (...) to frame contemporary efforts to improve access, conservation and innovation. (shrink)

This paper argues that the heritage represented by a museum should be seen not just in its individual objects but also in the relationships between them. The Conservatoire Nationale des Arts et Métiers and the Science Museum in London, the earliest great European science museums, were deeply concerned with the relationship between science and practice. The foundation speeches of the Deutsches Museum emphasised the concern with both past and future. Such ancestry provided hard-to-escape templates within which collections were built up (...) over the subsequent century and more. Thus the Science Museum’s biotechnology collection developed at the very end of the twentieth century and albeit based on detailed historical research reflects the same concerns with science–technology relations as could be seen in the 1876 Loan Exhibition which started off the Science Museum. The physical presence of such carefully-structured accumulations of objects could embody and reinforce the reality of such categories as pure and applied science. (shrink)

Until late in the nineteenth century, madder was the most popular natural red dye. Holland was the largest and best-known supplier. As early as the fourteenth and fifteenth centuries, the province of Zeeland and adjoining parts of the provinces of South Holland and Brabant developed into important producers. In the course of the seventeenth century these areas even succeeded in acquiring a monopoly position. Early in the nineteenth century, however, this position came under attack because France had gone over to (...) industrial production methods from around 1800, whereas Holland continued to produce with craft technologies. After 1820, as a result, a period of stagnation and decay set in. The fate of the Dutch madder industry would have been completely sealed if the production capacity of the French factories had been sufficiently large to satisfy the great increase in demand. Consequently, in Holland, after 1845, a process of revival based upon the French manufacturing methods began slowly and hesitatingly. This process started too late and was not persevered with sufficiently to regain lost markets. The Dutch producers remained strongly attached to their own out-dated, craft methods of production. (shrink)