Any adequate theory of chance must accommodate some version of David Lewis's ‘Principal Principle’, and Lewis has argued forcibly that believers in primitive propensities have a problem in explaining what makes the Principle true. But Lewis can only derive (a revised version of) the Principle from his own Humean theory by putting constraints on inductive rationality which cannot be given a Humean rationale.

Arguments to the effect that Church's thesis is intrinsically unprovable because proof cannot relate an informal, intuitive concept to a mathematically defined one are unconvincing, since other 'theses' of this kind have indeed been proved, and Church's thesis has been proved in one direction. However, though evidence for the truth of the thesis in the other direction is overwhelming, it does not yet amount to proof.

Viewing moral scepticism as the rejection of objective desirabilities, inductive scepticism may be seen as the rejection of objective believabilities. Moral scepticism leads naturally to amoralism rather than subjectivism, and inductive scepticism undermines not our practices of induction but only a view about justification. The two scepticisms together amount to the adoption of a defensibly narrow, formal view of reason.

Any adequate theory of chance must accommodate some version of David Lewis's ‘Principal Principle’, and Lewis has argued forcibly that believers in primitive propensities have a problem in explaining what makes the Principle true. But Lewis can only derive (a revised version of) the Principle from his own Humean theory by putting constraints on inductive rationality which cannot be given a Humean rationale.

This paper shows how John R. Commons’ analysis of a firm’s goodwill value gives analytical support to Professor Amartya Sen’s contention (BEQ, 1993) that business ethics makes economic sense. A firm’s market value consists of the value of both tangible and intangible capital, including the goodwill value of ongoing customer relations. If a firm is to defend its goodwill value, it needs to have the protection of the courts and to pursue ethical practices. The courts defend fair competition by giving (...) protection from unethical competitors while the firm defends its reputation with honest dealings.By implication, firms which depend on ongoing customer relations will tend to engage in more ethical business practices than firms which do not. Even a firm which makes a mistake that compromises its product’s safety may reduce the loss of goodwill value over time by admitting the mistake early rather than hiding it.Also by implication, the transition from a command socialist economy to a market economy cannot be made instantaneously since trust, reputation, and these ongoing customer relations-key institutions of market economics-cannot be generated instantaneously. (shrink)

This paper shows how John R. Commons’ analysis of a firm’s goodwill value gives analytical support to Professor Amartya Sen’s contention that business ethics makes economic sense. A firm’s market value consists of the value of both tangible and intangible capital, including the goodwill value of ongoing customer relations. If a firm is to defend its goodwill value, it needs to have the protection of the courts and to pursue ethical practices. The courts defend fair competition by giving protection from (...) unethical competitors while the firm defends its reputation with honest dealings.By implication, firms which depend on ongoing customer relations will tend to engage in more ethical business practices than firms which do not. Even a firm which makes a mistake that compromises its product’s safety may reduce the loss of goodwill value over time by admitting the mistake early rather than hiding it.Also by implication, the transition from a command socialist economy to a market economy cannot be made instantaneously since trust, reputation, and these ongoing customer relations-key institutions of market economics-cannot be generated instantaneously. (shrink)

In many regions around the world, those at highest risk for acquiring HIV are young adults and adolescents. Young men who have sex with men in the USA are the group at greatest risk for HIV acquisition, particularly if they are part of a racial or ethnic minority group.1 Adolescent girls and young women have the highest incidence rates of any demographic subgroup in sub-Saharan Africa.2 To reverse the global AIDS pandemic’s toll on these high-risk groups, it is important to (...) deploy the most effective HIV prevention tools to young MSM in the USA, to adolescent girls and young women in sub-Saharan Africa, and to any other adolescents and young adults at high risk for HIV as products are proven to be safe and efficacious. Although prevention interventions with proven efficacy, such as oral pre-exposure prophylaxis, are available,3–8 they have not been sufficient to stem the tide and an expanded prevention toolkit is urgently needed to serve these populations. The field of HIV prevention continues to identify promising leads in the development of new biomedical prevention products, either delivering antiviral drug topically or systemically. The dapivirine ring has been shown to provide modest protection and is currently being tested in open label studies while injectable cabotegravir is being tested in a large efficacy trial for preventing HIV acquisition. Advances in the field of HIV prevention mean that scientists and regulators must plan for how they will bring prevention tools to populations at high risk for HIV as they conduct efficacy and effectiveness trials. For instance, safety data from younger age groups can also be used in combination with efficacy data from adult studies, where appropriate, as bridging studies to expand labelling to younger ages. If these …. (shrink)

How much of our ordinary moral thought can we make sense of using a model of practical reason in which value is seen as subjective? There are already problems with showing strength of will not to be irrational. If social obligations are conceived of instrumentally as in a tradition running from Hobbes through Hume to Mackie, and if we employ our strength of will to sacrifice our individual projects in favor of them, the problems become insuperable.