What accounts for the continued lack of clarity over the legal procedures for the patenting of DNA sequences? The patenting system was built for a "bricks-and-mortar" world rather than an information economy. The fact that genes are both material molecules and informational systems helps explain the difficulty that the patent system is going to continue to have.
The important roles of prediction and prior experience are well established in music research and fit well with Clark's concept of unified perception, cognition, and action arising from hierarchical, bidirectional predictive processing. However, in order to fully account for human musical intelligence, Clark needs to further consider the powerful and variable role of affect in relation to prediction error.
In his Meditations Descartes tells us that he initially thought error might be avoided if he withheld assent “no less carefully from what is not plainly certain and indubitable than from what is obviously false.” For example, he thinks it plainly certain and indubitable that he is “sitting by the fire, wearing a winter cloak, holding this paper in my hands, and so on.” And yet even what is “plainly certain and indubitable” can be doubted. “I will suppose, then, not (...) that there is a supremely good God, the source of truth; but that there is an evil spirit, who is supremely powerful and intelligent, and does his utmost to deceive me.” Such a deceiver can spin illusions that appear indubitably real and true—of hands, fire, cloak, paper—and not only when there are none present in any particular case but even where there are none at all in any case. “I will suppose that sky, air, earth, colors, shapes, sounds and all external objects are mere delusive dreams, by means of which he lays snares for my credulity.”2 The deceiver hypothesis is the most difficult skeptical doubt Descartes must surmount in the remaining Meditations. I say the deceiver hypothesis, and for Descartes the deceiver is a mere possibility, raised so as to motivate the reconstitution of knowledge that follows. That there might be a powerful deceiver is itself a threat to knowledge for Descartes. Indeed even the possibility of an evil deceiver is so powerful a threat that Descartes must do nothing less than prove God’s existence to reestablish certainty. It is only at the end of his Meditations that Descartes can say, as if looking back on a hysterical moment, that the evil deceiver idea was “exaggerated” and “ridiculous.”3.. (shrink)
BackgroundPast research shows that physicians experience high ill-being but also high well-being.ObjectiveTo shed light on how medical faculty’s experiences of their job demands and job resources might differentially affect their ill-being and their well-being with special attention to the role that the work-life interface plays in these processes.MethodsQualitative thematic analysis was used to analyze interviews from 30 medical faculty at a top research hospital in Canada.FindingsMedical faculty’s experiences of work-life conflict were severe. Faculty’s job demands had coalescing effects on their (...) stress, work-life conflict, and exhaustion. Although supportive job resources helped to mitigate the negative effects of job demands, stimulating job resources contributed to greater work-life conflict, stress, and exhaustion. Thus, for these medical faculty job resources play a dual-role for work-life conflict. Moreover, although faculty experienced high emotional exhaustion, they did not experience the other components of burnout. Some faculty engaged in cognitive reappraisal strategies to mitigate their experiences of work-life conflict and its harmful consequences.ConclusionThis study suggests that the precise nature and effects of job demands and job resources may be more complex than current research suggests. Hospital leadership should work to lessen unnecessary job demands, increase supportive job resources, recognize all aspects of job performance, and, given faculty’s high levels of work engagement, encourage a climate that fosters work-life balance. (shrink)
Although the teaching of medical ethics and law in medical education is an old story that has been told many times in medical literature, recent studies show that medical students and physicians lack confidence when faced with ethical dilemmas and medico-legal issues. The adverse events rates and medical lawsuits are on the rise whereas many medical errors are mostly due to negligence or malpractices which are preventable. While it is true that many medical schools teach their students medical law and (...) ethics, there are wide variations in what is being taught because there is no universally agreed syllabus. Yet the knowledge of medical law and ethics is closely relevant to the medical profession and that failure in abiding the law may result in serious civil or even criminal consequences. While this paper does not propose to lay detailed analysis of the relevant areas of law or ethics, it proposes to cover some legal areas so as to highlight and bring to attention the need for a medical law and ethics course. This article also considers the problems faced and recommendation as to future directions to be taken with respect to teaching medical law and ethics. It concludes with a suggested course outline for the teaching of medical law and ethics. (shrink)
A theoretical strategy is proposed to integrate competing models of state breakdown by conceptualizing key concepts in these models at a more abstract level. The demographic model, which asserts that rapid population growth can bring about state breakdown when economic and political institutions are too rigid, is extracted from Goldstone's work. The geopolitical model, which argues that deteriorating geopolitical condition can bring about state breakdown if the state is too weak and the economy too unproductive, is extracted from Skocpol's and (...) Collins's works. The competing models are conceptualized as alternative and interacting routes to state breakdown where changing population pressure and geopolitical condition may generate integrative or disintegrative tendency depending on state power and productivity. A model describing four dimensions of state power-economic, military, political, and administrative-is constructed to incorporate various conceptualizations of the state in the state breakdown literature. Also integrated in the model is a third alternative route suggesting that rapid market development can generate disintegrative tendency if state power is too low. The synthesized model allows us to see that disintegrative/integrative tendency produced by one route may intensify or alleviate that generated by another route. (shrink)
Access to abortion is becoming increasingly restricted for many women in the United States. Besides the longstanding financial barriers facing low-income women in most states, a newer source of scarcity has emerged. The relatively small number of physicians willing to perform the procedure is compromising the ability of women in certain parts of the country to obtain an abortion.Do physicians have a duty to respond to this situation? Do they have a professional responsibility to ensure that abortions are reasonably available (...) to the women who want to terminate their pregnancies? Or, is abortion so morally and socially controversial as to remove any professional obligation to provide reasonable access?Both law and medical ethics have traditionally protected physicians’ freedom to refuse to perform any procedure, including abortion, that conflicts with their religious or other moral beliefs. (shrink)
Access to abortion is becoming increasingly restricted for many women in the United States. Besides the longstanding financial barriers facing low-income women in most states, a newer source of scarcity has emerged. The relatively small number of physicians willing to perform the procedure is compromising the ability of women in certain parts of the country to obtain an abortion.Do physicians have a duty to respond to this situation? Do they have a professional responsibility to ensure that abortions are reasonably available (...) to the women who want to terminate their pregnancies? Or, is abortion so morally and socially controversial as to remove any professional obligation to provide reasonable access?Both law and medical ethics have traditionally protected physicians’ freedom to refuse to perform any procedure, including abortion, that conflicts with their religious or other moral beliefs. (shrink)
This article is concerned with the ways in which literary spaces can become sexualized by the transfer of objects between women, as well as by the ways in which bodies themselves touch. It discusses how lesbian desire changes both spatial and temporal structures, via a consideration of the use of pearl imagery. In particular, it analyses the link between sexual, class and bodily construction in two texts: Daphne du Maurier's novel Rebecca and Carol Ann Duffy's poem ‘Warming Her Pearls’. (...) These texts encode contrasting ideas about the lesbian body, ideas that are discursively textured by the periods in which they were written and by the relative ideological resistance of their writers. While du Maurier's novel establishes a concept of spatial and temporal enclosure, Duffy's poem creates an unconfined and unstable lesbian body-text. Within this, the pearl can be seen as a subversive device, destructuring and stretching the parameters of lesbian desire. (shrink)
Music can reduce stress and anxiety, enhance positive mood, and facilitate social bonding. However, little is known about the role of music and related personal or cultural variables in maintaining wellbeing during times of stress and social isolation as imposed by the COVID-19 crisis. In an online questionnaire, administered in 11 countries, participants rated the relevance of wellbeing goals during the pandemic, and the effectiveness of different activities in obtaining these goals. Music was found to be the most effective activity (...) for three out of five wellbeing goals: enjoyment, venting negative emotions, and self-connection. For diversion, music was equally good as entertainment, while it was second best to create a sense of togetherness, after socialization. This result was evident across different countries and gender, with minor effects of age on specific goals, and a clear effect of the importance of music in people's lives. Cultural effects were generally small and surfaced mainly in the use of music to obtain a sense of togetherness. Interestingly, culture moderated the use of negatively valenced and nostalgic music for those higher in distress. (shrink)
Nanomedicine is yielding new and improved treatments and diagnostics for a range of diseases and disorders. Nanomedicine applications incorporate materials and components with nanoscale dimensions where novel physiochemical properties emerge as a result of size-dependent phenomena and high surface-to-mass ratio. Nanotherapeutics and in vivo nanodiagnostics are a subset of nanomedicine products that enter the human body. These include drugs, biological products, implantable medical devices, and combination products that are designed to function in the body in ways unachievable at larger scales. (...) Nanotherapeutics andin vivonanodiagnostics incorporate materials that are engineered at the nanoscale to express novel properties that are medicinally useful. These nanomedicine applications can also contain nanomaterials that are biologically active, producing interactions that depend on biological triggers. Examples include nanoscale formulations of insoluble drugs to improve bioavailability and pharmacokinetics, drugs encapsulated in hollow nanoparticles with the ability to target and cross cellular and tissue membranes and to release their payload at a specific time or location, imaging agents that demonstrate novel optical properties to aid in locating micrometastases, and antimicrobial and drug-eluting components or coatings of implantable medical devices such as stents. (shrink)
Hintikka has criticized psychologists for "hasty epistemologizing," which he takes to be an unwarranted transfer of ideas from psychology (a discipline dealing with questions of fact) into epistemology (a discipline dealing with questions of method and theory). Hamlyn argues, following Hintikka, that Gibson's theory of perception is an example of such an inappropriate transfer, especially insofar as Hamlyn feels Gibson does not answer several important questions. However, Gibson's theory does answer the relevant questions, albeit in a new and radical way, (...) which suggests that the alleged distinction between psychology and epistemology is suspect. In fact, contrary to Hintikka and Hamlyn's claims, Gibson's theory of perception appears to be a valuable source of epistemological as well as psychological ideas. (shrink)
Genomic research results and incidental findings with health implications for a research participant are of potential interest not only to the participant, but also to the participant's family. Yet investigators lack guidance on return of results to relatives, including after the participant's death. In this paper, a national working group offers consensus analysis and recommendations, including an ethical framework to guide investigators in managing this challenging issue, before and after the participant's death.
I explore how we negotiate sexual encounters with one another in language and consider the pragmatic structure of such negotiations. I defend three theses: Discussions of consent have dominated the philosophical and legal discourse around sexual negotiation, and this has distorted our understanding of sexual agency and ethics. Of central importance to good-quality sexual negotiation are sexual invitations and gift offers, as well as speech designed to set up safe frameworks and exit conditions. Sexual communication that goes well does not (...) just prevent harm; it enables forms of agency, pleasure, and fulfillment that would not otherwise be possible. (shrink)
The purpose of __Aquinas's Ethics__ is to place Thomas Aquinas's moral theory in its full philosophical and theological context and to do so in a way that makes Aquinas readily accessible to students and interested general readers, including those encountering Aquinas for the first time. Rebecca Konyndyk DeYoung, Colleen McCluskey, and Christina Van Dyke begin by explaining Aquinas's theories of the human person and human action, since these ground his moral theory. In their interpretation, Aquinas's theological commitments crucially shape (...) his account of the human person, human capacities for action, and human flourishing. The authors develop a comprehensive picture of Aquinas's thought, which is designed to help students understand how his concept of happiness and the good life are part of a coherent, theologically-informed worldview. Many studies of Aquinas naturally focus on certain areas of his thought and tend to assume a general knowledge of the whole. __Aquinas's Ethics_ _takes the opposite approach: it intentionally links his metaphysics and anthropology to his action theory and ethics to illuminate how the moral theory is built on foundations laid elsewhere. The authors emphasize the integration of concepts of virtue, natural law, and divine grace within Aquinas's ethics, rather than treating such topics in isolation or opposition. Their approach, presented in clear and deliberately non-specialist language, reveals the coherent nature of Aquinas's account of the moral life and of what fulfills us as human beings. The result is a rich and engaging framework for further investigation of Aquinas's thought and its applications. _"___Aquinas’s Ethics_ _is a perfect introduction to one of the most sophisticated and influential ethical systems in Western thought. DeYoung, McCluskey, and Van Dyke capture the brilliant clarity of Aquinas’s moral vision, offering an illuminating perspective true to both the theoretical depth and practical richness of Aquinas’s writings. Those new to Aquinas’s ideas will find this book eminently readable. Everyone—students and scholars alike—will appreciate its direct, distinctive voice and clear philosophical intelligence." —_Scott MacDonald, Norma K. Regan Professor in Christian Studies, Cornell University_ "__Aquinas's Ethics_ _is an excellent contribution to the literature on Aquinas and ethics, providing an integrated and robust account of the relationship between a metaphysics of human nature, natural law theory, and virtue theory. Showing these inextricable connections, it is very much like the work of St. Thomas himself, and suggests why so many lesser theories of ethics are unsatisfying for their lack of depth and comprehensive reach." —_John Kavanaugh, S.J., Saint Louis University_ “DeYoung, McCluskey, and Van Dyke have written the ideal introduction to Aquinas’s ethics, situating it in the broader context of his thinking about human nature and action. Although Aquinas cared more about—and wrote more about—ethics than about any other philosophical topic, it remains the most unjustly neglected aspect of his thought. I know of no better guide to that territory than this book.” —_Robert Pasnau, University of Colorado at Boulder_. (shrink)
A prevailing belief among Russia’s cultural elite in the early twentieth century was that the music of composers such as Sergei Rachmaninoff, Aleksandr Scriabin, and Nikolai Medtner could forge a shared identity for the Russian people across social and economic divides. In this illuminating study of competing artistic and ideological visions at the close of Russia’s “Silver Age,” author Rebecca Mitchell interweaves cultural history, music, and philosophy to explore how “Nietzsche’s orphans” strove to find in music a means to (...) overcome the disunity of modern life in the final tumultuous years before World War I and the Communist Revolution. (shrink)
Anthropogenic climate change is arguably one of the biggest problems that confront us today. There is ample evidence that climate change is likely to affect adversely many aspects of life for all people around the world, and that existing solutions such as geoengineering might be too risky and ordinary behavioural and market solutions might not be sufficient to mitigate climate change. In this paper, we consider a new kind of solution to climate change, what we call human engineering, which involves (...) biomedical modifications of humans so that they can mitigate and/or adapt to climate change. We argue that human engineering is potentially less risky than geoengineering and that it could help behavioural and market solutions succeed in mitigating climate change. We also consider some possible ethical concerns regarding human engineering such as its safety, the implications of human engineering for our children and society, and we argue that these concerns can be addressed. Our upshot is that human engineering deserves further consideration in the debate about climate change. (shrink)
