In this article, I focus on two moments of Nathaniel Kleitman's career, specifically that of his Mammoth Cave experiment in the 1930s and his consultation with the United States military in the 1940s–1950s. My interests in bringing these two moments of Kleitman's career together are to examine the role of nature and the social in his understanding of human sleep and the legacies these have engendered for sleep science and medicine in the present; more specifically, I am interested in Kleitman's (...) disallowance of napping in his scientific protocols, which may seem incidental until one apprehends the lack of napping as therapeutic treatment in modern sleep medicine. By forwarding a conception of historiography building on Raymond Williams’ “structures of feeling” and Gilles Deleuze and Felix Guattari's philosophy of immanence, I show how the work of William Dement in the 1970s to found a medicine of sleep and the eclipse of biphasic sleeping patterns as a biological and social possibility is indebted to Kleitman's scientific work. The modification of sleep is also the modification of society itself; and, as Kleitman argued, the harnessing of nature can lead to the finer entrenchments of human nature and society. (shrink)

Entropy-based algorithms have been suggested as robust estimators of electroencephalography (EEG) predictability or regularity. This study aimed to examine possible disturbances in EEG complexity as a means to elucidate the pathophysiological mechanisms in chronic stroke, before and after a brain computer interface (BCI)-motor observation intervention. Eleven chronic stroke subjects and nine unimpaired subjects were recruited to examine the differences in their EEG complexity. The BCI-motor observation intervention was designed to promote functional recovery of the hand in stroke subjects. Fuzzy approximate (...) entropy (fApEn), a novel entropy-based algorithm designed to evaluate complexity in physiological systems, was applied to assess the EEG signals acquired from unimpaired subjects and stroke subjects, both before and after training. The results showed that stroke subjects had significantly lower EEG fApEn than unimpaired subjects (p < 0.05) in the motor cortex area of the brain (C3, C4, FC3, FC4, CP3, CP4) in both hemispheres before training. After training, motor function of the paretic upper limb, assessed by the Fugl-Meyer Assessment-Upper Limb (FMA-UL), Action Research Arm Test (ARAT), and Wolf Motor Function Test (WMFT) improved significantly (p < 0.05). Furthermore, the EEG fApEn in stroke subjects increased considerably in the central area of the contralesional hemisphere after training (p < 0.05). A significant correlation was noted between clinical scales (FMA-UL, ARAT, and WMFT) and EEG fApEn in C3/C4 in the contralesional hemisphere (p < 0.05). This finding suggests that the increase in EEG fApEn could be an estimator of the variance in upper limb motor function improvement. In summary, fApEn can be used to identify abnormal EEG complexity in chronic stroke, when used with BCI-motor observation training. Moreover, these findings based on the fApEn of EEG signals also expand the existing interpretation of training-induced functional improvement in stroke subjects. Entropy-based analysis might serve as a novel approach to understanding the abnormal cortical dynamics of stroke and the neurological changes induced by rehabilitation training. (shrink)

Hand function improvement in stroke survivors in the chronic stage usually plateaus by 6 months. Brain-computer interface (BCI)-guided robot-assisted training has been shown to be effective for facilitating upper-limb motor function recovery in chronic stroke. However, the underlying neuroplasticity change is not well understood. This study aimed to investigate the whole-brain neuroplasticity changes after 20-session BCI-guided robot hand training, and whether the changes could be maintained at the 6-month follow-up. Therefore, the clinical improvement and the neurological changes before, immediately after, (...) and 6 months after training were explored in 14 chronic stroke subjects. The upper-limb motor function was assessed by Action Research Arm Test (ARAT) and Fugl-Meyer Assessment for Upper-Limb (FMA), and the neurological changes were assessed using resting-state functional magnetic resonance imaging. Repeated-measure ANOVAs indicated that long-term motor improvement was found by both FMA (F[2,26]= 6.367,p= 0.006) and ARAT (F[2,26]= 7.230,p= 0.003). Seed-based functional connectivity analysis exhibited that significantly modulated FC was observed between ipsilesional motor regions (primary motor cortex and supplementary motor area) and contralesional areas (supplementary motor area, premotor cortex, and superior parietal lobule), and the effects were sustained after 6 months. The fALFF analysis showed that local neuronal activities significantly increased in central, frontal and parietal regions, and the effects were also sustained after 6 months. Consistent results in FC and fALFF analyses demonstrated the increase of neural activities in sensorimotor and fronto-parietal regions, which were highly involved in the BCI-guided training.Clinical Trial Registration:This study has been registered atClinicalTrials.govwith clinical trial registration number NCT02323061. (shrink)

Ulrich Meyer defends a novel theory about the nature of time, and argues against the consensus view that time and space are fundamentally alike. He presents the first comprehensive defense of a 'modal' account, which emphasizes the similarities between times and possible worlds in modal logic, and is easily reconciled with the theory of relativity.

This book provides a unique, cogent, engaging account of environmental determinism that has long been much needed in the classroom and beyond." -- Andrew Sluyter, Associate Professor, Louisiana State University, USA This book pulls together major critiques of contemporary attempts to explain nature-society relations in an environmentally deterministic way. After defining key terms, it reviews the history of environmental determinism's rise and fall within geography in the early twentieth century. It discusses the key reasons for the doctrine's rejection and presents (...) alternative, non-deterministic frameworks developed within geography for analyzing the roles played by the environment in human affairs. The authors examine the rise in recent decades of neo-deterministic approaches to such issues as the demarcation of regions, the causes of civilizational collapse in prehistory, today's globally uneven patterns of human well-being, and the consequences of human-induced climate change. In each case, the authors draw on the insights and approaches of geography, the academic discipline most conversant with the interactions of society and environment, to challenge the widespread acceptance that such approaches have won. The book will appeal to those working on human-environmental research, international development and global policy initiatives. William B. Meyer is Associate Professor of Geography at Colgate University, USA. He is the author of several previous books, including Human Impact on the Earth, Americans and Their Weather: A History, and The Progressive Environmental Prometheans. His research interests include urban geography, environmental history, and the history of environmental thought. Dylan M.T. Guss works in the technology investment sector. (shrink)

Time's mysteries seem to resist comprehension and what remains, once the familiar metaphors are stripped away, can stretch even the most profound philosopher. In Of Time and Lamentation, Raymond Tallis rises to this challenge and explores the nature and meaning of time and how best to understand it. The culmination of some twenty years of thinking, writing and wondering about (and within) time, it is a bold, original, and thought-provoking work. With characteristic fearlessness, Tallis seeks to reclaim time from (...) the jaws of physics. For most of us, time is composed of mornings, afternoons, and evenings and expressed in hurry, hope, longing, waiting, enduring, planning, joyful expectation, and grief. Thinking about it is to meditate on our own mortality. Yet, physics has little or nothing to say about this time, the time as it is lived. The story told by caesium clocks, quantum theory, and Lorentz coordinates, Tallis argues, needs to be supplemented by one of moss on rocks, tears on faces, and the long narratives of our human journey. Our temporal lives deserve a richer attention than is afforded by the equations of mathematical physics.The first part of the book, "Killing Time" is a formidable critique of the spatialized and mathematized account of time arising from physical science. Part 2, "Human Time" examines tensed time, the reality of time as it is lived: what we mean by "now", how we make sense of past and future events, and the idea of eternity. (shrink)

Gerechtigkeit findet nicht nur zwischen Zeitgenossen statt - auch das Handeln früher lebender Menschen kann Ansprüche und Pflichten gegenwärtig und zukünftig lebender Menschen begründen. Der Autor entwickelt die Theorie einer historischen Gerechtigkeit auf der Basis der Pflichten zwischen den Generationen. Pluspunkte: Darstellung eines zentralen Themas aktueller politischer, ethischer und gesellschaftlicher Debatten Diskussionsgrundlage für Philosophen, Politikwissenschftler sowie interessierte Laien zeigt praktizierbare Lösungsansätze auf.

Many people living in highly industrialised countries and elsewhere emit greenhouse gases at a certain high level as a by-product of their activities, and they expect to be able to continue to emit at that level. This level is far above the just per capita level. We investigate whether that expectation is legitimate and permissible. We argue that the expectation is epistemically legitimate. Given certain assumptions, we can also think of it as politically legitimate. Also, the expectation is shown to (...) be morally permissible but with major qualifications. The interpretation of the significance of the expectation is compatible with the understanding that historical emissions should count in terms of fairly distributing the benefits of emission-generating activities over people’s lifetimes but constrains the way in which we may collectively respond to climate change. (shrink)

Y a-t-il une seule et unique morale dont on puisse se prévaloir aujourd'hui? Les réflexions philosophiques sur la morale se sont toujours combattues, remplacées, démenties au fil du temps, tout en étant chacune valable. Le stoïcisme, la morale de la vertu, le recours à la loi morale, l'utilitarisme sont autant de courants qui irriguent encore notre façon de penser. Mais laquelle de ces "visions" choisir? Et pourquoi choisir celle-là plutôt qu'une autre? Michel Meyer opère ici un retournement de la pensée (...) traditionnelle sur l'éthique. C'est parce que l'homme est un problème pour l'homme qu'il y a des réponses qu'on appelle la morale. Michel Meyer ne part plus des sujets éthiques (Moi, l'Autre) comme référents moraux, mais de la distance, plus ou moins grande, entre les individus. C'est la variation de cette distance qui influence nos choix quant au bien et au mal, à ce que l'on recherche ou à ce que l'on veut fuir ou éviter, et qui fera qu'on sera tantôt stoïcien, tantôt utilitariste ou kantien. Le positionnement des sujets les uns par rapport aux autres conduit à agir de telle ou telle manière, donc à adopter tel ou tel type de conduite morale et à juger ce qui est bien ou mal de façon différente. Le problème moral, c'est l'Autre comme problème, auquel il convient de répondre selon la distance qui nous sépare, nous divise ou nous rapproche, et auquel on répond toujours d'ailleurs, parce qu'il constitue une menace, un appel à l'aide, ou encore la nécessité de coopérer. Sans chercher à édicter de nouvelles règles ou de nouveaux préceptes, Michel Meyer replace les grandes théories morales, comme celles d'Aristote, de Kant, de Mill ou encore de Hume, dans un espace philosophique virtuel qui est leur espace de validité. Avec le concept de distance entre les êtres, il nous offre ainsi une approche nouvelle et synthétique de la morale. (shrink)

An entertaining series of logic problems and puzzles of increasing difficulty, and all relating important mathematical and logical concepts, includes mind-benders, paradoxes, metapuzzles, number exercises, and a mathematical novel.

This work subjects the fundamental ideas of Derrida, Lacan, Barthes and their followers to an examination and demonstrates the baselessness of post-Saussurean claims about the relations between language, reality and self.

Meyers examines the question of personal autonomy. She observes the effects of childrearing practices and sexual biases, and reflects upon the results in women. Annotation copyrighted by Book News, Inc., Portland, OR.

Tieren, UmweltUmweltethikPflanzenPflanze, Ökosystemen, Arten oder der ganzen Natur wirdStatus, moralischer in der tier- und umweltethischenPflichtgegenüber Tieren Diskussion ein eigener moralischer Status zuerkannt. Wir haben demnach nicht lediglich Pflichten gegenüber anderen Menschen, sondern auch gegenüber der Natur. In der DiskussionPflichtgegenüber der Natur um den moralischen Status von Tieren, Lebewesen und der Natur geht es einerseits um die Frage, wer überhaupt einen eigenen moralischen Status hat, also z. B. nur Tiere oder auch Pflanzen. Weiterhin wird diskutiert, welche moralischen Forderungen mit diesem Status (...) verbunden sindSchmerzvon Tieren. In der Begründung solcher Forderungen lassen sich verschiedene Herangehensweisen unterscheiden. Die so genannte „Ausdehnungsstrategie“ weitet moralisch relevante Überlegungen, die für den Umgang mit Menschen charakteristisch sind, auf die nicht-menschliche Natur aus. Dabei wird z. B. betont, dass auch Tiere über diejenigen Eigenschaften verfügen, die wir im Umgang mit anderen Menschen für moralisch relevant erachten. Diesen Fokus auf moralisch relevante Eigenschaften lehnen Kritiker dieser Strategie ab und schlagen stattdessen Alternativen zur Ausdehnungsstrategie vor. (shrink)

This article examines the relationship between Jeremy Waldron’s supersession thesis and compensation. Recently, Waldron has argued that claims for material compensation for the original injustice cannot be superseded. He limits supersession to issues of restitution. Waldron’s supersession thesis is frequently cited by opponents of claims based on historical injustice, so his view of compensation warrants close examination. In our article, we explain the details of Waldron’s ‘simple model’ of compensation, offer an internal critique of it, and try to sympathetically reconstruct (...) it. We contend that a crucial claim about this model does not work; his model would result in many more backward-looking compensatory claims than he realizes. Waldron’s allowing for material compensation claims from historical injustice is in tension with, or incompatible with, his long-expressed view that the spirit of the supersession thesis is that justice should be forward-looking and look to present-day costs. We have argued elsewhere that the abstract possibility that restitution claims may be superseded due to changing circumstances (what we call the ‘supersession thesis proper’) is separable from the question of whether justice has a forward-looking or backward-looking orientation. We argue here that Waldron’s model of compensation can best be made sense of through our distinction of ‘full supersession’ and ‘partial supersession.’ This allows us to show that Waldron’s model relies on a more strongly backward-looking orientation than he seems to endorse in his earlier works on restitution and his most recent article discussing compensation. We conclude by offering external criticisms of Waldron’s model of compensation. (shrink)

This book argues that Christian ethics urgently needs the category of tragic dilemmas. The author argues for a definition of tragic dilemmas that responds to philosophical concerns in a Christian context, using insights from the Protestant and Roman Catholic traditions, and in light of psychological evidence of moral injury after combat. Jackson-Meyer suggests that in a tragic dilemma an agent deliberates on, with sufficient knowledge, an issue that involves non-negotiable moral requirements in line with Christian obligations to protect human life (...) and the vulnerable. The agent is morally responsible for the harm caused and/or the obligation not acted upon. However, culpability is mitigated due to the constraints of the situation as long as the agent acts with, what Aquinas calls, "repugnance of the will." Tragic dilemmas are often the result of sin, a reality to which the Augustinian tradition is keenly attuned. When involvement in a tragic dilemma produces emotional harm, this has the power to undermine character because passions and the moral life are inextricably related. In turn, the agent's life is marred. In light of this harm, it is incumbent on Christian communities to offer opportunities for moral healing after tragic dilemmas. (shrink)

Review text: "Überzeugend ist A. Meyer vor allem in der souveränen kritischen Übersicht des Forschungsstandes, in der stringenten, die unterschiedlichen historiographischen Modelle voneinander abgrenzenden Systematisierung der Ergebnisse sowie in der Konsequenz bei der Durchführung ihres Anliegens."Mario Marino in: Berichte zur Wissenschaftsgeschichte 4/2009.

Business students are taught only technical knowledge without concern for holistic engagement; the reputation of business managers is declining due to their disregard for acting ethically. This graduate textbook introduces a business ethics from the.

Die Münchener Texte und Untersuchungen zur deutschen Literatur des Mittelalters (MTU), seit Band 102 beim Max Niemeyer Verlag, machen bisher nicht oder ungenügend erschlossene Texte, Stoffe und Gattungen zugänglich. Neben höfischem und Heldenepos und der Lieddichtung des Hohen und Späten Mittelalters sind vor allem auch Prosaschriften des weltlichen und geistlichen Bereichs, vom theologischen Traktat über die Mystik bis zum Spiel und zur Sachliteratur aus der mittelalterlichen Alltagswelt vertreten. Die Auswahl der publizierten Werke besorgt ein internationales Gremium von Mediävisten verschiedener Disziplinen.

Shaftesburys Dialog «The Moralists», ein Schlüsseltext der englischen Literatur und Ästhetik des frühen achtzehnten Jahrhunderts, ist bisher nur ideengeschichtlich interpretiert worden. Die vorliegende Studie zeichnet anhand weitgehend unbekannter Quellen aus dem Shaftesbury-Nachlass zum erstenmal die ebenso langwierige wie komplizierte Genese und Druckgeschichte des Textes nach. Shaftesburys hier erstmals veröffentlichte Briefe und Anweisungen an den Drucker und Verleger John Darby werfen neues Licht auf den Wandel der Typographie und der Buchgestaltung in der Epoche des englischen Neoklassizismus.

Die Historische Kommission zu Berlin betreibt die Erforschung der Landesgeschichte und der Historischen Landeskunde Berlin-Brandenburgs bzw. Brandenburg-Preußens in Form von wissenschaftlichen Untersuchungen, Vorträgen, Tagungen und Veröffentlichungen sowie durch Serviceleistungen. Dabei kooperiert die Kommission auch mit anderen Institutionen und begleitet wissenschaftliche und praktische Vorhaben von allgemeinem öffentlichen Interesse. In der Schriftenreihe werden die Ergebnisse der einzelnen wissenschaftlichen Projekte der Kommission veröffentlicht.

This volume works through spatio-temporal concepts to be found in imperial practices and their representations in a wide range of media. The individual cases investigated in the volume cover a broad spectrum of historical periods from ancient times up to the present. Well-known international scholars treat special cases of the topic, using cutting-edge theory and approaches stemming from historical, cartographic, religious, literary, media studies, as well as ethnography.