The UK Human Fertilisation and Embryology Authority was right to permit tissue typing preimplantation genetic diagnosisOn July 21 2004, the Human Fertilisation and Embryology Authority , Britain’s regulatory agency for reproductive technologies, revised its policy on preimplantation genetic diagnosis for tissue typing.1,2 The authority of the HFEA to enact such a policy was affirmed by the UK’s highest court, the House of Lords, on April 28 2005.3 Preimplantation genetic diagnosis combines in vitro fertilisation with genetic testing. In PGD, embryos generally (...) undergo biopsy prior to the eight cell stage, followed by genetic testing for a particular trait. Tissue typing PGD is done to identify an embryo that is tissue matched for a child suffering from a severe disease requiring bone marrow or cord blood stem cell transplantation and for whom no living donor exists. This procedure was first performed in 2000.4 Precise matching of tissue types is critical to successful tissue transplant, and the donors of such tissues are often referred to as “saviour siblings”.Where a tissue matched individual already exists, extracting bone marrow from that individual or collecting cord blood already in storage, rather than creating a match, presents the most immediate treatment alternative. Bone marrow donation from adults or other medically competent individuals is not generally ethically contested, and bone marrow donation from medically incompetent individuals is also permissible under certain conditions.5 Where no living tissue donor exists, however, intentionally creating a donor through tissue typing PGD is among a short list of possible treatment options.The July HFEA policy change makes PGD licensable in cases where tissue typing is the only purpose of testing. Previously, PGD was licensable in the UK only for disease testing, and tissue typing PGD was permissible only when …. (shrink)
A Ramsey statement denoted ${n \longrightarrow (k)^2_2}$ says that every undirected graph on n vertices contains either a clique or an independent set of size k. Any such valid statement can be encoded into a valid DNF formula RAM(n, k) of size O(n k ) and with terms of size ${\left(\begin{smallmatrix}k\\2\end{smallmatrix}\right)}$ . Let r k be the minimal n for which the statement holds. We prove that RAM(r k , k) requires exponential size constant depth Frege systems, answering a problem (...) of Krishnamurthy and Moll [15]. As a consequence of Pudlák’s work in bounded arithmetic [19] it is known that there are quasi-polynomial size constant depth Frege proofs of RAM(4 k , k), but the proof complexity of these formulas in resolution R or in its extension R(log) is unknown. We define two relativizations of the Ramsey statement that still have quasi-polynomial size constant depth Frege proofs but for which we establish exponential lower bound for R. (shrink)
A celebration of one of the most influential spiritual leaders of our time, Neem Karoli Baba, the enlightened guru who inspired a generation of seekers--including Ram Dass, Daniel Goleman, and Larry Brilliant--on life-altering journeys that helped change the world.In 1967, Ram Dass returned to the West from India and spread the teachings of his mysterious guru, Neem Karoli Baba, better known as Maharajji. Ram Dass's words about Maharajji's life-affirming wisdom resonated with a youth culture that had grown disillusioned with the (...) violence, civil discord, and crude materialism of modern civilization. Hundreds of Westerners travelled to India and experienced Maharajji's extraordinary presence directly until his death in 1973. His simple directives--love everyone, feed everyone, and remember God--opened their hearts and awakened their souls.What these followers brought back to the West has since changed the landscape of everyday life. Meditation is now mainstream; yoga studios are in every town; and mindfulness is practiced in elementary schools and boardrooms everywhere from Silicon Valley to Capitol Hill. A stirring piece of history, Love Everyone brings these stories to life, sharing for the first time the inspiring tales of the men and woman who followed the siren call of the East to the foothills of the Himalayas, then returned to forever reshape the world.A compelling and inspiring tribute to Maharajji from the Western men and women who knew him best, Love Everyone is a profound teaching on the power of love, as lasting and transformative as the truth, wisdom, and bliss of Maharajji. Parvati Markus is a developmental editor and writer of spiritually oriented non-fiction books and memoirs. She has worked on books by various members of the satsang, from Ram Dass's classic Be Here Now (before she went to India) to those since her time in India with Maharajji (1971-72)--Dada Mukerjee's By His Grace and The Near and the Dear to Krishna Das's recent Chants of a Lifetime. She is a former President of the Board of the Neem Karoli Baba Ashram and Temple and a former development consultant for the Global Peace Initiative of Women Religious and Spiritual Leaders, held at the U.N. in Geneva, Switzerland. She lives in West Palm Beach, Florida. (shrink)
Bruce Janz, Jessica Locke, and Cynthia Willett interact in this exchange with different aspects of Chakravarthi Ram-Prasad’s book Human Being, Bodily Being. Through “constructive inter-cultural thinking”, they seek to engage with Ram-Prasad’s “lower-case p” phenomenology, which exemplifies “how to think otherwise about the nature and role of bodiliness in human experience”. This exchange, which includes Ram-Prasad’s reply to their interventions, pushes the reader to reflect more about different aspects of bodiliness.
In lieu of an abstract, here is a brief excerpt of the content:Books ReceivedAt the Eleventh Hour: The Biography of Swami Rama. By Pandit Rajmani Tigunait, Ph.D. Honesdale, Pennsylvania: Himalayan Institute Press, 2002. Pp. 427. Hardcover $18.95.Awakening and Insight: Zen Buddhism and Psychotherapy. Edited by Polly Young Eisendrath and Shoji Muramoto. Hove, England: Brunner-Routledge, 2002. Pp. xii + 275. Paper $24.95.Beyond Metaphysics Revisited: Krishnamurti and Western Philosophy. By J. Richard Wingerter. Lanham, Maryland: University Press of America, 2002. Pp. vii + (...) 391. Hardcover $71.00.Bhāmatī and Vivaraṇa Schools of Advaita Vedānta: A Critical Approach. By Pulasth Soobah Roodurmun, foreword by V. N. Jha, and edited by Kanshi Ram. New Delhi: Motilal Banarsidass Publishers, 2002. Pp. xv + 297. Price not given.A Bibliography of Ananda Kentish Coomaraswamy. By James S. Crouch. New Delhi: Indira Gandhi National Centre for the Arts and Manohar Publishers and Distributors, 2002. Pp. 430. Price not given.Crisis Theory and World Order: Heideggerian Reflections. By Norman K. Swazo. Albany: State University of New York Press, 2002. Pp. x + 289. Hardcover $78.50. Paper $26.95.Devotional Literature in South Asia: Current Research 1997-2000: Proceedings of the Eighth International Conference on Early Literature in New Indo-Aryan Languages, Leuven, 23-26 August 2000. Edited by Winand M. Callewaert and Dieter Taillieu. New Delhi: Manohar Publishers and Distributors, 2002. Pp. xxii + 324. Price not given.Dharma Bell and Dhāraṇī Pillar: Li Po's Buddhist Inscriptions. By Paul W. Kroll. Kyoto: Italian School of East Asian Studies, 2001. Pp. viii + 95. Price not given.Essays on the Moral Philosophy of Mengzi. Edited, with introduction, by Xiusheng Liu and Philip J. Ivanhoe. Indianapolis and Cambridge: Hackett Publishing Company, 2002. Pp. xiv + 249. Hardcover $39.95. Paper $16.95. Professional price $12.95.Ethical Questions: East and West. Edited by Bina Gupta. Lanham, Maryland: Rowman and Littlefield Publishers, 2002. Pp. vi + 279. Hardcover $70.00. Paper $26.95.Ethical Relativism and Universalism. By Saral Jhingran. New Delhi: Motilal Banarsidass Publishers, 2001. Pp. xiv + 385. Price not given.Genius-In Their Own Words: The Intellectual Journeys of Seven Great 20th Century [End Page 431] Thinkers. Edited and with introduction by David Ramsay Steele, foreword by Arthur C. Danto. Chicago and La Salle: Open Court, 2002. Pp. xxii + 366. Paper $24.95.The Hatha Yoga Pradipika. The original Sanskrit by Svatmarama, an English translation by Brian Dana Akers. Woodstock, New York: YogaVidya.com, 2002. Pp. xii + 115. Hardcover $19.95. Paper $11.95.Human Rights and Chinese Thought: A Cross-Cultural Inquiry. By Stephen C. Angle. New York: Cambridge University Press, 2002. Pp. xviii + 285. Hardcover $65.00. Paper $23.00.Indestructible Truth: The Living Spirituality of Tibetan Buddhism. By Reginald A. Ray. Boston and London: Shambhala Publications, 2002. Pp. x + 495. Paper $17.95.Introduction to Eastern Thought. By Marietta Stepaniants. Edited by James Behuniak and translated by Rommela Kohanovskaya. Lanham, Maryland: AltaMira Press, a division of Rowman and Littlefield Publishers, 2002. Pp. xiv + 293. Hardcover $69.00. Paper $24.95.Jainism and Ecology: Nonviolence in the Web of Life. Edited by Christopher Key Chapple. Cambridge: Harvard University Press for the Center for the Study of World Religions, 2002. Pp. xliv + 252. Hardcover $32.95. Paper $22.95.Mediating the Power of Buddhas: Ritual in the Mañjuśrīmūlakalpa. By Glenn Wallis. Albany: State University of New York Press, 2002. Pp. xiii + 263. Hardcover $86.50. Paper $29.95.Methodology in Religious Studies: The Interface with Women's Studies. Edited by Arvind Sharma. Albany: State University of New York Press, 2002. Pp. xi + 253. Hardcover $78.50. Paper $26.95.Persons and Valuable Worlds: A Global Philosophy. By Eliot Deutsch. Lanham, Maryland: Rowman and Littlefield Publishers, 2002. Pp. x + 309. Hardcover $80.00. Paper $34.95.Philosophy and Art in Gurdjieff's Beelzebub: A Modern Sufi Odyssey. By Anna T. Challenger. Amsterdam and New York: Editions Rodopi B.V., 2002. Pp. xi + 145. Paper EUR 27,00, U.S. $25.00.The Pratyabhijñā Philosophy. By G. V. Tagare. New Delhi: Motilal Banarsidass Publishers, 2002. Pp. xii + 165. Price not given.Reflections on Reality: The Three Natures and Non-Natures in the Mind-Only School: Dynamic Responses to ong-ka-a's The... (shrink)
The article deals with the algorithm of encrypting graphic information using transformation matrixes. It presents the actions that can be done with the image. The article also gives algorithms for forming matrixes that are created with the use of random processes. Examples of matrixes and encryption results are shown. Calculations of the analysis of combinations and conclusions to them are carried out. The article shows the possibilities and advantages of this image encryption algorithm. The proposed algorithm will allow to transmit (...) encrypted information through open communication channels. The algorithm uses all possible actions that can be done with the image, namely: image resizing, adding redundant elements to the image, changing the location of the pixels, changing the brightness of the image pixels, inverting the image pixels, changing the colours of the images pixels. A randomized approach to matrix formation will make it impossible to use neural systems. The algorithm of the implementation of writing encryption code is rather simple. It is not possible to decrypt the image without a key as the number of possible combinations is extremely large. This algorithm can be used in the military, intelligence, information security. Encryption does not require significant computing or RAM resources. This algorithm can be implemented in WEB-technology and in mobile applications, it has no recursive functions and loop in loop. The algorithm hides the image size, which in turn adds extra protection. Redundant elements will not allow neural networks to compare pixels. Changing colors, changing brightness, inversion by random processes will not allow neural networks to find the decryption function. The article considers an image encryption algorithm that will give a possibility to generate a key. The key will be a set of two-dimensional arrays formed in a randomized manner. A randomized approach to matrix formation will make it impossible to use neural systems. The algorithm uses all possible actions that can be done with the image, namely: Image resizing. Adding redundant elements to the image. Changing the location of the pixels. Changing the brightness of the image pixels. Inverting the image pixels. Changing the colours of the images pixels. The pixel positioning matrix gives us! combinations. The pixel brightness change matrix gives us 8 *! combinations. The pixel inversion matrix gives us 8 *! combinations. The pixel colour change matrix gives us 6 *! Combinations. The total number of combinations N is equal to: It is not possible to decrypt the image without a key as the number of possible combinations is extremely large. The algorithm of the implementation of writing encryption code is rather simple. This algorithm can be used in the military, intelligence, information security. The advantage of this algorithm is the fact that the encrypted image can be transmitted through open chann. (shrink)
Given two strings, text t of length n, and pattern p = p1…pk of length k, and given a natural number w, the subsequence matching problem consists in finding the number of size w windows of text t which contain pattern p as a subsequence, i.e. the letters p1,…,pk occur in the window, in the same order as in p, but not necessarily consecutively . Subsequence matching is used for finding frequent patterns and association rules in databases. We generalize the (...) Knuth–Morris–Pratt pattern matching algorithm; we define a non-conventional kind of RAM, the MP-RAMs which model more closely the microprocessor operations; we design an O on-line algorithm for solving the subsequence matching problem on MP-RAMs. (shrink)
In recent years Russell´s view that there are singular propositions, namely propositions that contain the individuals they are about, has gained followers. As a response to a number of puzzles about attitude ascriptions several Russellians (as I will call those who accept the view that proper names and indexicals only contribute their referents to the propositions expressed by the sentences in which they occur), including David Kaplan and Nathan Salmon, have drawn a distinction between what proposition is believed and how (...) it is believed.1 While it is generally agreed upon among Russellians that this distinction needs to be drawn there is considerable disagreement as to what exactly the distinction amounts to and what role the what and the how should play. The most plausible option seems to be to not assign a semantic value to the cognitive role played by the name or indexical in the sentence assented to. But recently Mark Richard2 has attempted to make the cognitive role affect truth values by building it into the truth conditions of belief reports.3 I will argue that Richard’s attempt fails to satisfy our pretheoretical intuitions about the sharing of beliefs. Furthermore, and more surprisingly, I will argue that Richard’s theory makes it virtually impossible for us to judge whether or not most belief reports are true or false, since doing so would involve what I call RAM probing, which would require viewing elements that are essentially private. (shrink)
Öz Çalışmanın konusu irfanî geleneğin on beşinci yüzyıldaki önemli temsilcilerinden ve aynı zamanda İbnü’l-Arabî’nin takipçilerinden biri olan İbn Türke’nin varlık mertebelerine dair görüşleridir. Konu, İbn Türke’nin varlık ve varlığın mertebeleri ile ilgili düşüncelerinden hareketle hazırlanmıştır. Birincil kaynakların esas alındığı bu çalışmada, İbn Türke ve Ekberî geleneğin önemli temsilcilerinin eserlerine müracaat edilmiştir. Çalışmanın amacı, felsefe ve kelâmın yanı sıra tasavvuf felsefesinin en önemli konularından biri olan varlık düşüncesi ve varlık mertebelerini İbn Türke’nin görüşleri çerçevesinde ele alarak âlemdeki varoluşun hakikatinin ne olduğu, (...) insanoğlunun özünün nereden geldiği gibi temel sorulara cevap olabilecek özgün bir çalışma ortaya koymaktır. Bu çalışmayla; varlığın bir ve tek hakikat olduğu, Hak’tan feyz ederek görünür âlemde ortaya çıkan her şeyin O’nun isim ve sıfatlarının tecellisi olduğu, her ne kadar Hak’tan ayrıymış gibi görünse de aslında Hakk’a doğru sonsuz bir dönüş içerisinde olduğu, dolayısıyla tek varlıktan kaynaklı çok sayıda varlığın esasen yokluğa mahkûm olduğu ve asıl varlığın Allah olduğu sonucuna varılmıştır. (shrink)
