: Because an influenza pandemic would create the most serious hardships for those who already face most serious hardships, countries should take special measures to mitigate the effect of a pandemic on existing social inequalities. Unfortunately, there is little evidence that anybody is thinking about that.

The prospect of using cell-based interventions to treat neurological conditions raises several important ethical and policy questions. In this target article, we focus on issues related to the unique constellation of traits that characterize CBIs targeted at the central nervous system. In particular, there is at least a theoretical prospect that these cells will alter the recipients' cognition, mood, and behavior—brain functions that are central to our concept of the self. The potential for such changes, although perhaps remote, is cause (...) for concern and careful ethical analysis. Both to enable better informed consent in the future and as an end in itself, we argue that early human trials of CBIs for neurological conditions must monitor subjects for changes in cognition, mood, and behavior; further, we recommend concrete steps for that monitoring. Such steps will help better characterize the potential risks and benefits of CBIs as they are tested and potentially used for treatment. (shrink)

© 2019 The Author. Background: The phenomenon of being 'with woman' is fundamental to midwifery as it underpins its philosophy, relationships and practices. There is an identified gap in knowledge around the 'with woman' phenomenon from the perspective of midwives providing care in a variety of contexts. As such, the aim of this study was to explore the experiences of being 'with woman' during labour and birth from the perspective of midwives' working in a model where care is provided by (...) a known midwife. Methods: A descriptive phenomenological design was employed with ten midwives working in a 'known midwife' model who described their experiences of being 'with woman' during labour and birth. The method was informed by Husserlian philosophy which seeks to explore the same phenomenon through rich descriptions by individuals revealing commonalities of the experience. Results: Five themes emerged 1) Building relationships; 2) Woman centred care; 3) Impact on the midwife; 4) Impact on the woman; and 5) Challenges in the Known Midwife model. Midwives emphasised the importance of trusting relationships while being 'with woman', confirming that this relationship extends beyond the woman - midwife relationship to include the woman's support people and family. Being 'with woman' during labour and birth in the context of the relationship facilitates woman-centred care. Being 'with woman' influences midwives, and, it is noted, the women that midwives are working with. Finally, challenges that impact being 'with woman' in the known midwife model are shared by midwives. Conclusions: Findings offer valuable insight into midwives' experiences of being 'with woman' in the context of models that provide care by a known midwife. In this model, the trusting relationship is the conduit for being 'with woman' which influences the midwife, the profession of midwifery, as well as women and their families. Descriptions of challenges to being 'with woman' provide opportunities for professional development and service review. Rich descriptions from the unique voice of midwives, provided insight into the applied practices of being 'with woman' in a known midwife model which adds important knowledge concerning a phenomenon so deeply embedded in the philosophy and practices of the profession of midwifery. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

This article examines overpopulation as a basis for historical interpretation. Drawing on the ideas of T.R. Malthus, Elizabeth Kolbert, John Lovelock, Lynn Margulis, and Edward O. Wilson, I make the case that the only concept of ‘progress’ that accurately describes the human enterprise is the uncontrolled growth of population. I explain why a Malthusian/Gaia interpretation is not a historicist or eschatological narrative, like Hegelian idealism, Marxism, fundamentalist religion, or ‘end of history’ neoliberalism. My article also includes a discussion of the (...) ideas and prescriptions of contemporary commentators like physicist, Adam Frank, and the philosophers, John Gray, and Roy Scranton. What makes my article distinctive is bringing together ideas of population theory through a lens of sociobiology and post-humanist philosophy. Through this interpretive synthesis, I form a basis for recasting history as the record of the growing imbalance of our species in light of the unprecedented crises of the environment that are its byproduct. I conclude with the idea that regardless of whether the world is dying or simply going through a fundamental chaotic transformation, the role of the critical-rational historian remains the same: to tell the truth as best as she or he can know it. (shrink)

This volume contains essays by some of the leading scholars in the study of the Jewish religious ideas in the Second Temple period, that led up to the development of early forms of Rabbinic Judaism and Christianity. Close attention is paid to the cosmological ideas to be found in the Ancient Near East and in the Hebrew Bible and to the manner in which the translators of the Hebrew Bible into Greek reflected the creativity with which Judaism engaged Hellenistic ideas (...) about the cosmos and the creation. The concepts of heaven and divine power, human mortality, the forces of nature, combat myths, and the philosophy of wisdom, as they occur in 2 Maccabees, Ben Sira, Wisdom of Solomon and Tobit, are carefully analysed and compared with Greek and Roman world-views. There are also critical examinations of Dead Sea scroll texts, early Jewish prayers and Hebrew liturgical poetry and how they these adopt, adapt and alter earlier ideas. The editors have included appreciations of two major figures who played important roles in the study of the Second Temple period and in the history and development of the ISDCL, namely, Otto Kaiser and Alexander Di Lella, who died recently and are greatly missed by those in the field."--Provided by publisher. (shrink)

It is known that, on average, people adapt their choice of memory strategy to the subjective utility of interaction. What is not known is whether an individual's choices are boundedly optimal. Two experiments are reported that test the hypothesis that an individual's decisions about the distribution of remembering between internal and external resources are boundedly optimal where optimality is defined relative to experience, cognitive constraints, and reward. The theory makes predictions that are tested against data, not fitted to it. The (...) experiments use a no-choice/choice utility learning paradigm where the no-choice phase is used to elicit a profile of each participant's performance across the strategy space and the choice phase is used to test predicted choices within this space. They show that the majority of individuals select strategies that are boundedly optimal. Further, individual differences in what people choose to do are successfully predicted by the analysis. Two issues are discussed: the performance of the minority of participants who did not find boundedly optimal adaptations, and the possibility that individuals anticipate what, with practice, will become a bounded optimal strategy, rather than what is boundedly optimal during training. (shrink)

Many recent writers in the philosophy of mathematics have put great weight on the relative categoricity of the traditional axiomatizations of our foundational theories of arithmetic and set theory. Another great enterprise in contemporary philosophy of mathematics has been Wright's and Hale's project of founding mathematics on abstraction principles. In earlier work, it was noted that one traditional abstraction principle, namely Hume's Principle, had a certain relative categoricity property, which here we term natural relative categoricity. In this paper, we show (...) that most other abstraction principles are not naturally relatively categorical, so that there is in fact a large amount of incompatibility between these two recent trends in contemporary philosophy of mathematics. To better understand the precise demands of relative categoricity in the context of abstraction principles, we compare and contrast these constraints to stability-like acceptability criteria on abstraction principles, the Tarski-Sher logicality requirements on abstraction principles studied by Antonelli and Fine, and supervaluational ideas coming out of Hodes' work. (shrink)

Fallacies are things people commit, and when they commit them they do something wrong. What kind of activities are people engaged in when they commit fallacies, and in what way are they doing something wrong? Many different things are called fallacies. The diversity of the use of the concept of a fallacy suggests that we are dealing with a family of cases not related by a common essence. However, we suggest a simple account of the nature of fallacies which encompasses (...) them all, viz., the term “fallacy” is our most general term for criticizing any general procedure used for the fixation of beliefs that has an unacceptably high tendency to generate false or unfounded beliefs, relative to that method of fixing beliefs. Very different sorts of things called fallacies are examined in the light of this account, e.g., denying the antecedent, circular arguments, so-called informal fallacies, and propositions said to be fallacies. We do not provide a theory of fallacies. Still, on our account pretty much all of those things that have been called fallacies are fallacies, and they have been called fallacies for pretty much the same reasons. (shrink)

This collection explores the meaning of maps and of map-making in the modern world.

Inspired by impossibility theorems of social choice theory, many democratic theorists have argued that aggregative forms of democracy cannot lend full democratic justification for the collective decisions reached. Hence, democratic theorists have turned their attention to deliberative democracy, according to which “outcomes are democratically legitimate if and only if they could be the object of a free and reasoned agreement among equals” (Cohen 1997a, 73). However, relatively little work has been done to offer a formal theory of democratic deliberation. This (...) article helps fill that gap by offering a formal theory of three different modes of democratic deliberation: myopic discussion, constructive discussion, and debate. We show that myopic discussion suffers from indeterminacy of long run outcomes, while constructive discussion and debate are conclusive. Finally, unlike the other two modes of deliberation, debate is path independent and converges to a unique compromise position, irrespective of the initial status quo. (shrink)

I argue that rather than aiming at the well-being of those whom we love, we should aim to share in their ends. The former stance runs the risk of being objectionably paternalistic and, as I explain, only the latter makes reciprocal relationships possible. I end by diagnosing our attraction to the idea that we should promote our loved-ones’ well-being.

"Williams's masterful translation satisfies (at last!) a long-standing need. There are lots of good translations of Augustine's great work, but until now we have been forced to choose between those that strive to replicate in English something of the majesty and beauty of Augustine's Latin style and those that opt instead to convey the careful precision of his philosophical terminology and argumentation. Finally, Williams has succeeded in capturing both sides of Augustine's mind in a richly evocative, impeccably reliable, elegantly readable (...) presentation of one of the most impressive achievements in Western thought--Augustine's Confessions." --Scott MacDonald, Professor of Philosophy and Norma K. Regan Professor in Christian Studies, Cornell University. (shrink)

Benacerraf’s 1965 multiple-reductions argument depends on what I call ‘deferential logicism’: his necessary condition for number-set identity is most plausible against a background Quineanism that allows autonomy of the natural number concept. Steinhart’s ‘folkist’ sufficient condition on number-set identity, by contrast, puts that autonomy at the center — but fails for not taking the folk perspective seriously enough. Learning from both sides, we explore new conditions on number-set identity, elaborating a suggestion from Wright.

Rawls' requirement that citizens of liberal democracies support only policies which they believe can be justified in 'public reason' depends on a certain ideal for the relationships between citizens. This is a valuable ideal, and thus citizens have reasons to try to achieve it. But it is not always possible to find the common ground that we would need in order to do so, and thus we should reject Rawls' strong claim that we have an obligation to defend our views (...) in public reason. Because I recognize that we have strong reasons to conduct our political enquiry within the guidelines of political liberalism, but deny that we always have an obligation to do so, one might call my view 'permissive political liberalism'. (shrink)

I attempt to vindicate our authority to create new practical reasons for others by making choices of own own. In The Doctrine of Right Kant argues that we have an obligation to leave the Juridical State of Nature and found the state. In a less familiar passage in Religion within the Bounds of Mere Reason he argues for an obligation to leave what he calls the Ethical State of Nature and join together in the Moral Community. I read both texts (...) as addressing and trying to resolve a tension between our individual freedom and our authority to make claims on one another. I explicate the political argument, and then develop the view that Kant sketches in the Religion, arguing that regarding others as capable of making choices that give you reasons to act is a condition of the full exercise of your autonomy. (shrink)

The Moral Nexus develops and defends a new interpretation of morality—namely, as a set of requirements that connect agents normatively to other persons in a nexus of moral relations. According to this relational interpretation, moral demands are directed to other individuals, who have claims that the agent comply with these demands. Interpersonal morality, so conceived, is the domain of what we owe to each other, insofar as we are each persons with equal moral standing. The book offers an interpretative argument (...) for the relational approach. Specifically, it highlights neglected advantages of this way of understanding the moral domain; explores important theoretical and practical presuppositions of relational moral duties; and considers the normative implications of understanding morality in relational terms. The book features a novel defense of the relational approach to morality, which emphasizes the special significance that moral requirements have, both for agents who are deliberating about what to do and for those who stand to be affected by their actions. The book argues that relational moral requirements can be understood to link us to all individuals whose interests render them vulnerable to our agency, regardless of whether they stand in any prior relationship to us. It also offers fresh accounts of some of the moral phenomena that have seemed to resist treatment in relational terms, showing that the relational interpretation is a viable framework for understanding our specific moral obligations to other people. (shrink)

Christine M. Korsgaard has had a profound influence on moral philosophy over the past forty years. Through her writing and teaching she has developed a distinctive, rigorous, and historically informed way of thinking about ethics, agency, and the normative dimension of human life more generally. The twelve original essays in this volume are written in her honor on the occasion of her retirement from teaching. They engage questions that recur in her work: Why are we obligated to do what morality (...) demands? What features of our nature make us subject to moral obligation? What does it mean to be autonomous and responsible for what we do? What do we owe to nonhuman animals? Contributors include Stephen Darwall, Kyla Ebels-Duggan, Barbara Herman, Richard Moran, Japa Pallikkathayil, Faviola Rivera-Castro, T.M. Scanlon, Tamar Schapiro, Sharon Street, David Sussman, Sigrún Svavarsdóttir, and David Velleman. These essays shed light on Korsgaard's own views while staking out provocative new positions on the topics that feature centrally in her own work. (shrink)

We often come to value someone or something through experience of that person or thing. You may thereby come to embrace a value that you did not grasp prior to the experience in question. Moreover, it seems that in a large and important subset of cases you could not have fully appreciated that value merely by considering a report of the reasons or arguments that purport to establish that it is valuable. Despite its ubiquity, this phenomenon goes missing in a (...) great deal of contemporary work in ethics and political philosophy. In this paper I further specify the phenomenon of interest by developing a series of examples. Then I support the claim that philosophers routinely overlook it by surveying several significant philosophical positions that do so. (shrink)

It is often alleged that an agent is morally responsible in a liability sense for a transgression just in case s/he deserves a negative interpersonal response for that transgression, blaming responses such as resentment and indignation being paradigms. Aside from a few exceptions, guilt is cited in recent discussions of moral responsibility, if at all, as merely an effect of being blamed, or as a reliable indicator of moral responsibility, but not itself an explanation of moral responsibility. In this paper, (...) I argue that an agent is morally responsible in a liability sense for a transgression just in case s/he deserves to feel moral guilt for that transgression. I argue that this alternative view offers all that the predominant blame-focused view offers, while also solving some puzzling features of moral responsibility. Specifically, it offers a compelling way to reconcile conflicting intuitions about the suberogatory, and allows those who do not understand what Darwall calls ‘second-personal’ reasons to be morally responsible for their immoral acts. (shrink)

Kant’s political theory stands in the social contract tradition, but departs significantly from earlier versions of social contract theory. Most importantly Kant holds, against Hobbes and Locke, that we have not merely a pragmatic reason but an obligation to exit the state of nature and found a state. Kant holds that each person has an innate right to freedom, but it is possible to simultaneously honor everyone’s right only under the rule of law. Since we are obligated to respect each (...) person’s right to freedom, and can do so only in a state, we are obligated to submit to the authority of the state if we have one, and to establish one if we do not. In the first half of the essay I reconstruct this argument in more detail. In the second half I survey four points of controversy: (i) What is the relationship between Kant’s political philosophy and his moral philosophy? (ii) How does the innate right to freedom support the postulate that we are permitted to acquire property and other private rights? (iii) How does the postulate support an obligation to found the state? (iv) How should we understand Kant’s views about political revolutions? (shrink)

Neo-Fregeans have been troubled by the Nuisance Principle, an abstraction principle that is consistent but not jointly satisfiable with the favored abstraction principle HP. We show that logically this situation persists if one looks at joint consistency rather than satisfiability: under a modest assumption about infinite concepts, NP is also inconsistent with HP.

I argue that we cannot adequately characterize the aims of education in terms of some formal conception of what it is to think well. Implementing any such aim requires reliance on and communication of further, substantive normative commitments. This reveals that a standard contrast between an old-fashioned approach to education that aims to communicate a particular normative outlook, and a progressive approach that aims to develop skills of critical reasoning and reflection is confused and misleading.

This article improves two existing theorems of interest to neologicist philosophers of mathematics. The first is a classification theorem due to Fine for equivalence relations between concepts definable in a well-behaved second-order logic. The improved theorem states that if an equivalence relation E is defined without nonlogical vocabulary, then the bicardinal slice of any equivalence class—those equinumerous elements of the equivalence class with equinumerous complements—can have one of only three profiles. The improvements to Fine’s theorem allow for an analysis of (...) the well-behaved models had by an abstraction principle, and this in turn leads to an improvement of Walsh and Ebels-Duggan’s relative categoricity theorem. (shrink)

The injective version of Cantor’s theorem appears in full second-order logic as the inconsistency of the abstraction principle, Frege’s Basic Law V (BLV), an inconsistency easily shown using Russell’s paradox. This incompatibility is akin to others—most notably that of a (Dedekind) infinite universe with the Nuisance Principle (NP) discussed by neo-Fregean philosophers of mathematics. This paper uses the Burali–Forti paradox to demonstrate this incompatibility, and another closely related, without appeal to principles related to the axiom of choice—a result hitherto unestablished. (...) It discusses both the general interest of this result, its interest to neo-Fregean philosophy of mathematics, and the potential significance of the Burali–Fortian method of proof. (shrink)

Objects appear to fall into different sorts, each with their own criteria for identity. This raises the question of whether sorts overlap. Abstractionists about numbers—those who think natural numbers are objects characterized by abstraction principles—face an acute version of this problem. Many abstraction principles appear to characterize the natural numbers. If each abstraction principle determines its own sort, then there is no single subject-matter of arithmetic—there are too many numbers. That is, unless objects can belong to more than one sort. (...) But if there are multi-sorted objects, there should be cross-sortal identity principles for identifying objects across sorts. The going cross-sortal identity principle, ECIA2 of Cook and Ebert (2005), solves the problem of too many numbers. But, I argue, it does so at a high cost. I therefore propose a novel cross-sortal identity principle, based on embeddings of the induced models of abstracts developed by Walsh (2012). The new criterion matches ECIA2’s success, but offers interestingly different answers to the more controversial identifications made by ECIA2. (shrink)

I argue that unfortunate formative circumstances do not undermine the warrant for either responsibility or blame. I then diagnose the tendency to think that formative circumstances do matter in this way, arguing that knowledge of these circumstances can play an essential epistemic role in our interpersonal interactions.

Berislav Marušić’s On the Temporality of Emotions is a lovely book. Marušić confronts a puzzle about grief and anger that many will find familiar from their own.

Our ordinary talk reflects a deep tension in the way that we think about love. On the one hand, we regard love as an especially important expression of our agency. Yet, on the other hand, we also think of love as something that happens to us, in the face of which we are passive and can be powerless. While it’s hard to see how to hold these two ways of thinking of love together, in this paper I argue that we (...) must find some way of doing so. I argue that we must think of love as a contentful attitude attributable to its agent, an expression of our selves. But familiar ways of understanding agency sort love into the category of things that happen to us, rather than that of things that we do: You cannot love at will, nor is love an attitude to which you could reason. I conclude that questions about the relationship of our agency to what we love are not superficial, but stem from deep tensions about the relationship between love and reasons. A resolution to these difficulties would provide important insight not only into the character of love, but also the nature of agency, and its relationship to values, reasoning and reasons. (shrink)

We propose the solution concept of directional equilibrium for the multidimensional model of voting with general spatial preferences. This concept isolates alternatives that are stable with respect to forces applied by all voters in the directions of their gradients, and it extends a known concept from statistics for Euclidean preferences. We establish connections to the majority core, Pareto optimality, and existence and closed graph, and we provide non-cooperative foundations in terms of a local contest game played by voters.

Many thinkers agree that facilitating the development of students’ autonomy is a proper aim of education generally and higher education in particular. I defend a version of the autonomy view, but not as I think its other advocates imagine it. I suggest that an important aim of education is the facilitation of intellectual virtues. What is right about the idea that education should facilitate students’ autonomy is best captured in virtue terms as intellectual charity and humility.

I argue that political liberals should not support the monopoly of a single educational approach in state sponsored schools. Instead, they should allow reasonable citizens latitude to choose the worldview in which their own children are educated. I begin by defending a particular conception of political liberalism, and its associated requirement of public reason, against the received interpretation. I argue that the values of respect and civic friendship that motivate the public reason requirement do not support the common demand that (...) citizens “bracket” their comprehensive commitments in politics. Rather, citizens should seek to enact policies the justification of which is compatible with the truth of their fellow reasonable citizens’ worldviews. Next I argue that no single educational approach can meet this standard of justification. Many believe that state sponsored education in a pluralist, liberal society ought to present multiple worldviews in a neutral way. I argue that this aspiration is unrealizable, and no other educational model will plausibly meet the justificatory demand. Finally, I address two objections to my favored alternative: that it may allow for the inculcation of disrespect, and that it violates children’s autonomy. Against the first, I claim that political liberals have no grounds for thinking that reasonable citizens will seek to inculcate disrespect. Finally, I argue that there is no conception of autonomy that can sustain the second. (shrink)

The principle that children’s freedom should be preserved in their upbringing is sometimes thought to provide an alternative to imposing a particular conception of the good on them. But to sustain the alternative we must distinguish between those desires and proclivities that are educated into a person and those that are his own. Several philosophers appeal to innate or presocial tendencies to ground this distinction, but that approach fails. The ability to exercise first person authority over a desire or commitment (...) provides a better conception of what it is for such a state to be one’s own. But such desires and commitments are not distinct from those educated into a person. While the ideal of autonomy, conceived in these terms, can still provide some guidance for upbringing, it will not substitute for teaching children a conception of the good. (shrink)

I articulate and defend the most central claims of contemporary Kantian moral theory. I also explain some of the most important internal disagreements in the field, contrasting two approaches to Kantian ethics: Kantian Constructivism and Kantian Realism. I connect the former to Kant’s Formula of Universal Law and the latter to his Formula of Humanity. I end by discussing applications of the Formula of Humanity in normative ethics.

Kant rejects all of the standard accounts of the dependence of morality on religious claims or commitment. He nevertheless thinks that morality “leads to” religion. I defend an account of this “leading to” relationship, arguing that it is the result of Kant’s struggle to capture the practical import of the consequences of our actions within a moral theory that rejects the idea that we must maximize the good. On this view, the best way to acknowledge that the outcomes of our (...) actions matter, while maintaining uncompromising commitment to the moral law, is to hope in God. (shrink)

We should approach this topic with great fear and respect. It is not a merely “academic” issue. Human rights are trampled upon in the East as in the West, in the North as in the South of our planet. Granting the part of human greed and sheer evil in this universal transgression, could it not also be that Human Rights are not observed because in their present form they do not represent a universal symbol powerful enough to elicit understanding and (...) agreement? (shrink)