Social change; Sufism; doctrines; religious aspects.

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

Logic; Islam and philosophy; Tunisia; early works to 1800.

90 nian dai, Du Weiming xian sheng de geng duo jing li zai yu kai zhan "wen hua Zhongguo" de lun yu."Wen hua Zhongguo" zhuo mo zui duo de shi ru jia de ren wen jing shen, yi jiu zheng jiang ru jia ru shi de jia zhi qu xiang he fan su ren wen zhu yi hun wei yi tan de yin xiang, tu xian ru jia yi mai xiang cheng de pi pan jing shen.

On Islamic philosophy with special reference to logic in Islamic philosophy.

This paper summarizes the author’s view and research on the concept of ‘Spiritual Humanism’ as a cross-cultural, historical heritage and theoretical framework for contemporary research in philosophy. It builds on comprehensive scholarship conducted over the last decades within a plurality of leading academic communities. It reflects the author’s commitment to include Chinese Philosophy and intellectual history within the international scholarly canon.

本书从哲学、历史和文学多个视角，重新梳理了先秦儒家思想形态，还原了思孟学派的渊源与传承。.

Work on the philosophy of law and rights.

Mencius’ claim that human nature is good is well known among students of classical Confucian thought. It has been taken for granted that underlying Mencius’ deceptively simple thesis is an appeal to intuition. No persuasive argument is offered, except the insistence that the moral propensities, such as the “four germinations” are inherent in human nature. A corollary of this insistence is the unquestioned belief that human beings all have the inner ability to commiserate with others, to feel ashamed of themselves, (...) to have a sense of humbleness, and to differentiate right from wrong. And the only example of an attempt to “prove” the thesis which approximates a kind of empiricist procedure seems no more than a commensense observation. (shrink)