CONSCIOUSNESS AND THE BRAIN SELF-REGULATION PARADOX The relationship of consciousness to biology has intrigued mankind thoroughout recorded history. However, little progress has been made not only in understanding these issues but also in raising fundamental questions central to the problem. As Davidson and Davidson note in their introduction, William James suggested, almost a century ago in his Principles of Psychology, that the brain was the organ of mind and be havior. James went so far as to suggest that the remainder (...) of the Principles was but a "footnote" to this central thesis. This volume brings together diverse biobehavioral scientists who are addressing the various aspects of the mindlbrainlbodylbehavior issue. Although some of the authors have previously published together in other volumes, by and large the particular combination of authors and topics selected by the editors makes this volume unique and timely. Unlike the Consciousness and Self-Regulation series (Schwartz & Shapiro, 1976, 1978), also published by Plenum, this volume is devoted entirely to a psychobiological approach to consciousness. Although readers will differ in their interest in specific chapters, the well-rounded investigator who is concerned with the psychobiology of consciousness will want to become intimately acquainted with all the views presented in this volume. As noted by the individual contributors, the topic of this volume stimulates fundamental questions which, on the surface, may appear trivial, yet, on further reflection, turn out to have deep significance. (shrink)

The brain and body need to adapt constantly to changing social and physical environments. A key mechanism for this adaptation is the ‘stress response’, which is necessary and not negative in and of itself. The term ‘stress’, however, is ambiguous and has acquired negative connotations. We argue that the concept of allostasis can be used instead to describe the mechanisms employed to achieve stability of homeostatic systems through active intervention (adaptive plasticity). In the context of allostasis, resilience denotes the ability (...) of an organism to respond to stressors in the environment by means of the appropriate engagement and efficient termination of allostatic responses. In this review, we discuss the neurobiological and organismal factors that modulate resilience, such as growth factors, chaperone molecules and circadian rhythms, and highlight its consequences for cognition and behavior. (shrink)

Human aggression and war are mediated by culture and social evolution. Human beings have a wide range of possible behaviors and possible cultural responses to aggression and the possibility of fear. This article analyzes the psychobiological dimensions of aggression and war, and proposes a way of approaching the complex interrelationship between biology, psychology, and culture.

From a scientific perspective, hunger can be regarded as an identifiable conscious sensation which can be distinguished from other conscious states. The hunger state can be measured and is a marker of the existence of underlying biological processes. Measured hunger is functional and is normally associated with the act of eating. However, the conscious state of hunger, although driven physiologically, is not exclusively determined by biology; there is an environmental influence that can modulate its intensity and periodicity, and cultural factors (...) that shape the appropriateness of the expression of hunger. Within a psychobiological framework, hunger can be considered as the expression of a ‘need state’ which mediates between biological requirements and environmental satisfaction. Our empirical studies show that hunger is clearly associated with biological signals and is central to the relationship between energy expenditure and energy intake. (shrink)

Behavioral science research in American universities was promoted and influenced by philanthropic foundations. In the 1920s and 1930s, Rockefeller philanthropies in particular financed behavioral science research projects that promised to fulfill their mandates to `improve mankind', mandates that foundation officers transformed into an informal, loosely defined human engineering effort. Controlling behavior, especially sexual and social `dysfunction', was a major priority. The behavioral scientists at Yale University, led by president James R. Angell and `psychobiologist' Robert M. Yerkes, tapped into foundation largesse (...) by crafting research programs that promised to contribute to the `welfare of mankind' through the investigation and control of sexual and social behavior. Foundation officers supported Yerkes' primate research because they accepted his premise that analyzing chimpanzee sexual behavior would yield valuable insights into the evolutionary underpinnings of human development and would thus give investigators the necessary information to ameliorate dysfunction. Between 1925 and 1940, philanthropic foundations contributed approximately $7 million to support the Yale Institute of Human Relations and the affiliated Yerkes Laboratories of Primate Biology. Yet, disappointment with the results of the Yale appropriations ultimately contributed to foundation officers turning away from behavioral sciences and toward biological sciences as they continued their efforts to improve mankind through human engineering. This article examines the interaction between foundation officers and Yale behavioral scientists to illustrate how scientific entrepreneurs successfully crafted rationales about human sexuality to solicit funds, how philanthropic foundation officers became enmeshed in the behavioral science research projects that they funded, and how a cooperative human engineering effort at Yale developed in the 1920s and unraveled in the 1930s. (shrink)

Mature rats were kept on protein-deficient diets to test the hypothesis that late-onset protein restriction results in deficits and to determine the feasibility of doing nutrition-behavior research with old naive animals. A 3% low-protein (LP) group and a 24% adequate-protein (AP) pair-fed control were used. Body weights and plasma protein concentrations were lower and exploratory behavior and motor coordination were poorer for LP rats. Both groups preferred the 24% protein diet. LP rats habituated slower and failed to overcome an initial (...) black preference on an oddity discrimination learning task. Nutrition-behavioral research with older rats is feasible, and late-onset protein restriction produces psychobiological deficits. (shrink)

I present different approaches to psychological causality usually neglected. The debate between mechanism and dualism in psychology has obscured other pluralistic philosophical positions. I begin by setting out Schopenhauer’s position, the "analogic" one, which includes, in a pluralistic view, diverse causations (mechanical, stimulate, and motive reasons) but with a monism of the will at the noumenal level. Then, I review other approaches in psychology and biological sciences: dialectical, constructivist and biosemiotics. All agree to see reality as plural and self-constituted. En (...) este trabajo presento distintos enfoques sobre la causalidad psicológica normalmente desatendidos. El debate entre mecanicismo y dualismo en la psicología ha oscurecido otras posiciones filosóficas pluralistas. Comienzo por exponer la postura "analógica" de Schopenhauer, que incluye -de forma pluralista- una diversidad de causaciones (mecánica, estimular y causalidad por motivos) pero con un monismo de la voluntad en el plano nouménico. Después reviso otros enfoques dialécticos en la psicología y en las ciencias biológicas: dialécticas, constructivistas y biosemióticas. Todos ellos coinciden en ver la realidad como plural y autoconstituida. (shrink)

This textbook explores both the psychological and biological influences on the development of behavior, using research on both animal and human subjects to support principles and hypotheses.

Cloninger's Psychobiological Model of Personality and Strelau's Regulative Theory of Temperament - analysis of their associations in a Polish sample The present study explores the relationship between Cloninger scales and Strelau's Regulative Theory of Temperament traits. Cloninger's psychobiological model identifies four dimensions of temperament and three dimensions of character. RTT proposes the traits of Briskness, Perseveration, Sensory Sensitivity, Emotional Reactivity, Endurance and Activity as the basic dimensions underlying individual differences. The relationships between the dimensions of Cloninger's Temperament and Character and (...) Strelau's Regulative Theory of Temperament are investigated in a sample of 282 participants. Data analysis demonstrated some significant correlations between the two models. The strongest associations were found between the dimension of Harm Avoidance from Cloninger's concept and Strelau's RTT traits. However, there is not enough evidence to suggest that the two models offer an alternative way of explaining individual differences. According to RTT, temperamental traits are expressed in formal characteristics of behavior and every kind of behavior can be described in the same formal categories. In the Psychobiological Model of Personality the traits are characterized rather by the content or goals of behavior. In this model, in addition to underlining the biological variation of heritable traits, the social, cultural and phenotypical levels of behavior are reflected. (shrink)

Empathy represents one of the basic forms of human expression. Empathy evolved to facilitate social behavior. The perception action model, extended to empathy, is an exciting paradigm in which to undertake contemporary cognitive and comparative neuroscience. It renders the perception of events as an active affair, both when watching others, and when performing actions.

The argument of berkley for the existence sex differences in pain is based on biological factors. We suggest that the psychological evidence for such differences is more substantial.

The ArgumentThis paper is concerned with “holism” as a German cultural “style” of doing psychobiology in Central Europe between the two world wars. The paper takes its starting point from a critical analysis of Forman's writings on nationalism versus internationalism in interwar German science, and the alleged “accommodation” of interwar German physics to an antiscientific, irrationalist culture. The paper argues that psychobiological holism was not just a reaction against nineteenth-century atomistic or mechanistic approaches to modeling life and mind; it also (...) represented a domestically directed answer from within the German biomedical scientific community to broad religious and cultural “disenchantment.” As such, holistic psychobiology emerges as a phenomenon that challenges us with at least four levels of discourse: experimental/clinical, epistemological/philosophical, existential/religious, and ideological/political. The paper defends the methodological appropriateness of a collective case-study approach to the problem of holism as a multilevel discourse. It concludes by offering a preliminary contextualized analysis of the thought of three representative holistic leaders of the time: behavioral biologist and ethologist Jakob von Uexküll; clinical neurologist Constantin von Monakow; and neuropsychiatrist Kurt Goldstein. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Adolph Meyer’s Psychobiology in Historical Context, and Its Relationship to George Engel’s Biopsychosocial ModelEdwin R. Wallace IV (bio)Keywordspsychobiology, integrative models of psychiatry, biopsychosocial modelBefore addressing the importance of Adolf Meyer and the question of his impact on the biopsychosocial model of the psychoanalytical internist George Engel, let us tersely sketch the history of functionalism in medicine/psychiatry, and of the nineteenth/early twentieth century’s progressive abandonment of it in favor of (...) basic science reductive models of “disease,” not illness.FunctionalismWhereas Hippocratic physicians diagnosed diatheses in terms of humoral excesses or deficiencies, their primary emphasis was on the ill person. They began with careful histories of the patient’s complaints and his or her daily life course, customary activities, typical foods and beverages imbibed, and the exacerbation or relief of symptoms associated with any or all of these. They also asked questions about his physical and social environment. They carefully looked for any clinically pertinent signs, and might physically examine the patient or his excretions. When they arrived at a diagnosis (say, an excess of yellow or black bile, or of blood or phlegm), they would educate the patient about it and discuss possible approaches. Although leeching, emetics, or purgatives might be prescribed, “dietetics” was the core of the treatment. Much more than recommendations about dietary intake, this involved conversations about “lifestyle” management in general: exercise, fresh air, habit changes, and perhaps bathing in mineral waters or spas. If the patient were “melancholic” (which then included what we would now consider a variety of psychiatric disorders), he or she might be prescribed daily swimming and other forms of vigorous exercise, conversations with a philosopher, [End Page 347] attendance at theatrical comedies, or even referral to an Asklepian temple for “incubation sleep” and priestly dream interpretation. Often doctors worked closely with physical trainers, to whom they sent their patients. In short, their orientation was holistic (“mind”/”body” integration), directed first and foremost toward an individual ill person.In the second century, C.E. Galen, despite his humoral and anatomical pathologies, was similarly holistic or functionalist. He resorted to a variety of physical examinational methods while also attending to the patient’s mental/emotional status. He described one case where he was attending a woman for syncopal episodes. His examinations of her included his customary attention to the pulse. During one evening session, a servant entered and happened to mention that he had just seen the handsome Pylades dancing. Suddenly her pulse became irregular and she fainted straight away. This led Galen to consider love sickness, and perhaps not humoral or organ pathology. He tested his hypothesis during subsequent visits. Whenever another dancer or actor was mentioned, her pulse remained regular and her sensorium alert, but when Pylades was mentioned the irregular pulse and fainting recurred. Because she was married, Galen realized her insoluble conflict, and treated her accordingly.From the fall of Rome until the rise of University Medicine in the later Middle Ages, medical lore and doctoring was in monastic hands—each monastery had its clerical medic, who might also attend outsiders. They were attuned to the traditional triad of major mental disorders—mania, melancholia, and phrenitis—which they explained somatically. However, they also encountered lesser mental/emotional disorders for which they developed their own nosology. “Scrupulosity,” for example, characterized a committed monk with an unrealistic sense of sinfulness and guilt—which often drove him to self-mortification such as flagellation, hair shirts with chains underneath, and so forth, for which the remedy was kindly pastoral counseling. “Accedia” was akin to our “dysthymia,” whose sufferer was affected by sadness, lassitude, and impaired capacity to carry out the monastic routine. This was viewed as straddling the boundary between sickness and sin. Routine physical labor (“occupational therapy”) and prayers, confession, penance, and “pep talks” were prescribed.When universities with medical schools arose in the latter Middle Ages, students’ educations were mostly bookish and theoretical. Hippocratic and Galenic somatic orientations were still preeminent. (Vesalius would not publish his illustrated anatomical text until 1543.) Dietetics and purgatives, bloodletting, and so on were still favored treatments. Nevertheless, doctors gave considerable time and attention to their patients as ill... (shrink)

This study investigated the effects of psychobiological characteristics of non-obese women with a high level of weight suppression on explicit-implicit and approach-avoidance response toward food cues, depending on hunger-satiety states. The 634 participants were divided into two groups according to their weight history. If the difference between their highest weight over the last year and their current weight was more than 5%, they were assigned to the “H-WS” group. If the difference in weight was less than 5%, they were assigned (...) to the “low level of weight suppression” group. Explicit approach and avoidance toward food were measured by self-report questionnaires. Implicit approach and avoidance toward food cues were measured using an eye-tracker. Fasting blood samples were obtained to measure fasting serum leptin levels. After this, participants consumed a standard breakfast to control the satiety level. After breakfast, explicit-implicit approach-avoidance responses were repeatedly measured at the satiety states. Self-reported body shape concerns, drive for thinness, ambivalent food craving, and bulimic behavior were also assessed. The results showed that the H-WS group had lower leptin levels, and higher body shape concerns, drive for thinness, ambivalent food craving, and bulimic behaviors compared to the L-WS group. At the explicit level, the H-WS group reported lower approach and higher avoidance to food compared to the L-WS group, regardless of hunger-satiety state. Whereas, at the implicit level, the H-WS group showed higher approach during satiety rather than during hunger states. Regardless of the hunger-satiety state, there were no significant group differences with regard to implicit avoidance between the two groups. Thus, we confirmed that a high level of avoidance toward foods was observed in the H-WS group at the explicit level but not at the implicit level. Moreover, in contrast with a high level of explicit avoidance toward palatable foods, inhibition for implicit approach toward high-calorie foods seemed to be blunted after food consumption in the H-WS group. These inconsistencies may be associated with ambivalent food craving and vulnerability to bulimic behavior among H-WS individuals. (shrink)

There is good reason to suppose that religious belief and ritual are manifestations of the archetypal blueprint for human existence encoded in the genetic structure of our species. As a consequence, religion has become a focus of study for psychobiologists and neuroscientists. However, scientific explanations of religious experience do not “explain away” such experience nor are they substitutes for the experience itself. On the contrary, scientific discoveries may be seen as corroboration of religious insights into the unus mundus, the essential (...) oneness of all experience, which links human nature with the nature of the cosmos. (shrink)

The aim of this contribution is to broaden the concept of musical meaning from an abstract and emotionally neutral cognitive representation to an emotion-integrating description that is related to the evolutionary approach to music. Starting from the dispositional machinery for dealing with music as a temporal and sounding phenomenon, musical emotions are considered as adaptive responses to be aroused in human beings as the product of neural structures that are specialized for their processing. A theoretical and empirical background is provided (...) in order to bring together the findings of music and emotion studies and the evolutionary approach to musical meaning. The theoretical grounding elaborates on the transition from referential to affective semantics, the distinction between expression and induction of emotions, and the tension between discrete-digital and analog-continuous processing of the sounds. The empirical background provides evidence from several findings such as infant-directed speech, referential emotive vocalizations and separation calls in lower mammals, the distinction between the acoustic and vehicle mode of sound perception, and the bodily and physiological reactions to the sounds. It is argued, finally, that early affective processing reflects the way emotions make our bodies feel, which in turn reflects on the emotions expressed and decoded. As such, there is a dynamic tension between nature and nurture, which is reflected in the nature-nurture-nature cycle of musical sense-making. (shrink)

George Engel’s biopsychosocial model was associated with the critique of biomedical dogmatism and acknowledged the historical precedence of the work of Adolf Meyer. However, the importance of Meyer’s psychobiology is not always recognized. One of the reasons may be because of his tendency to compromise with biomedical attitudes. This paper restates the Meyerian perspective, explicitly acknowledging the split between biomedical and biopsychological approaches in the origin of modern psychiatry. Our present-day understanding of this conflict is confounded by reactions to ‘anti-psychiatry.’ (...) Neo-Meyerian principles can only be reestablished by a challenge to biomedicine that accepts, as did Meyer, the inherent uncertainty of medicine and psychiatry. (shrink)

The first scientific questionnaire to establish gender and sexual “intermediate” identities “objectively” was published in 1899 by the internationally renowned sexologist and pioneer of LGBTI emancipation, Magnus Hirschfeld (1868–1935). In this article, I show that this questionnaire changed how interactions took place between psycho-medical professionals and people who did not conform to sexual or gender norms. Rhetorically, the questionnaire created a delicate balance between self-expression and objectification of the subject. It broke down already existing semiautobiographical case histories into a list (...) of characteristics, behaviour, and inclinations; all predicated on a conventional binary view of gender. I conclude that the questionnaire paradoxically activated and reified conventionally binary-gendered phenomena precisely by offering gender nonconformist people a robust frame for (gender-fluid) self-understanding; an inheritance still haunting us today. (shrink)