Institute for Biomedical Ethics, Geneva University Medical School * Corresponding author: Médecins Sans Frontières (OCG), rue de Lausanne 78, CH-1211 Geneva 21, Switzerland. Tel.: +41 (0)22 849 89 29; Fax: +41 (0)22 849 84 88; Email: philippe_calain{at}hotmail.com ' + u + '@' + d + ' '//--> Abstract Outbreaks of filovirus (Ebola and Marburg) hemorrhagic fevers in Africa are typically the theater of rescue activities involving international experts and agencies tasked with reinforcing national authorities in clinical management, biological diagnosis, (...) sanitation, public health surveillance and coordination. These outbreaks can be seen as a paradigm for ethical issues posed by epidemic emergencies, through the convergence of such themes as: isolation and quarantine, privacy and confidentiality and the interpretation of ethical norms across different ethnocultural settings. With an emphasis on the boundaries between public health investigations and research, this article reviews specific challenges, past practices and current normative documents relevant to the application of ethical standards in the course of outbreaks of filovirus hemorrhagic fevers. Aside from commonly identified issues of informed consent and institutional review processes, we argue for more clarity over the specification of which communities are expected to share benefits, and we advocate for the use of collective definitions of duty to care and standard of care. We propose new elaborations around existing normative instruments, and we suggest some pathways toward more comprehensive approaches to the ethics of research in outbreak situations. CiteULike Connotea Del.icio.us What's this? (shrink)

Definition of the problem: In Germany, clinical ethics is still in the state of development. Ethics consultation is very new and rare in the clinical setting in German university hospitals. Therefore this paper describes the clinical ethics activities at the Medical Center of Philipps University, Marburg, regard to ethics consultation in a case report. Clinical ethics rounds at the Surgical Intensive Care Unit are organized according to the theory and practice of the ethics consultation service at the Medical (...) Center of the University of Virginia, established by J.C. Fletcher, F.G. Miller and J.J. Fins. (shrink)

The three-yearly conference of Italian Society for Logic and Philosophy of Science (SILFS) has taken place in Bergamo, the 15th, 16th and 17th December 2010. The charming venue has been the former convent of Sant’Agostino, nowadays University of Bergamo. The conference program has been structured distinguishing plenary and parallel sessions: the first ones were 40 minutes long and designed for international guests: S. Abramsky from the Wolfson College of Oxford, A. Hagar from Indiana University, P. Janich from Philipps Universitaet (...) of Marburg and S. Okasha from University of Bristol. The complete program of the conference can be downloaded here: . We followed all the plenary sessions, and the first part of our report concerns them. There is just the exception of professor S. Psillos’ talk, which was indeed programmed, but didn’t take place due to greek unrest of the last December. The second part of our report concers the parallel sessions, that were 20 minutes long and designed for concurrent talks split between subject areas. We will keep this division into areas in our report and we chose four talks per area. However, it must be said that we had not watch the parallel sessions completely, since their being simoultaneous. This means that our review of the conference will be perspective, both because of subjective standpoint and because of the mentioned limitation. Still we hope we can offer a quite complete picture of the three-days conference, as we hope this overview may be considered as a general review of it. Just a few words must be still said to introduce to our review. The structure of each review will consists in a presentation of the talk’s author(s) (which we faithfully copy hereinafter) followed by a brief remark by us. Since many compliments could be surely done to the SILFS’ organization and to the University of Bergamo, an overall effect seems hard to be drawn, because of some arising perplexities. Although these are just our shared impressions about the conference, we think they must be remembered. One could note outward that the conference have had three official languages: English, French and Italian. Apparently, this is something that has not been justified since French has been useless and Italian has often prevented the comprehension by foreigner attendance. Many defections have taken place, something that could be said about the conformity with the program (in spite of the high number of speeches). Of course these defections have been caused by different reasons, but they become an indication of lack of professionalism as the number grows. Coming to an estimation of the inner issues, first we are seriously puzzled about the selection criterion (if any) which the SILFS has chosen the invited speakers with. One can notice that excellent talks have been put together to shallow speech without substantial scientific commitment. One has to keep in mind that who is just worthless, much lowers the general level. The topics have been various, although many were historical reconstruction and the "historiographic" approach in the study of Philosophy of Science seems therefore prevailing. Those talks whose subject was Logic and its applications, have been the highest-quality ones, by the fact that they were close to contemporary researches. More specifically, we would like to quote those concerning Quantum Computation and Logic of Quantum Mechanics. Talks of Philosophy of Biology and Cognitive Science were first-rate works, too, having showed high proficiency, though even specialistic topics were often technically handled, to the detriment of laymen (as us). (shrink)

The aim of this paper is to shed light on and develop what I call a phenomenological conception of experiential justification. According to this phenomenological conception, certain experiences gain their justificatory force from their distinctive phenomenology. Such an approach closely connects epistemology and philosophy of mind and has recently been proposed by several authors, most notably by Elijah Chudnoff, Ole Koksvik, and James Pryor. At the present time, however, there is no work that contrasts these different versions of PCEJ. This (...) paper not only bridges this gap, but also reveals problems in current versions of PCEJ. Consequently, I argue for a new version of PCEJ that focuses on what is given within experience and not on how what is given pushes me towards believing something. (shrink)

The aim of this paper is twofold. The first is an interpretative one as I wish to provide a detailed account of Husserl’s conception of experiential justification. Here Ideas I and Introduction to Logic and Theory of Knowledge: Lectures 1906/07 will be my main resources. My second aim is to demonstrate the currency and relevance of Husserl’s conception. This means two things: Firstly, I will show that in current debates in analytic epistemology there is a movement sharing with Husserl the (...) basic idea that certain experiences gain their justificatory force simply from their distinctive phenomenal character. Secondly, I shall reveal the benefits of Husserl’s specific version of this view. Thus, one of my aims is to show that debates in current analytic epistemology could profit from adopting certain Husserlian elements. More precisely, I will defend Husserl’s claim that perceptual experiences are justifiers due to their self-giving phenomenal character as opposed to the currently popular view that it is the phenomenology of pushiness that makes them justifiers. To put it differently, what matters is what is originally given within experience and not how you feel about what is given. (shrink)

In his influential paper “Grasping the Third Realm,” John Bengson raises the question of how we can non-accidentally grasp abstract facts. What distinguishes successful intuition from hallucinatory intuition? Bengson answers his “non-accidental relation question” by arguing for a constitutive relationship: The intuited object is a literal constituent of the respective intuition. Now, the problem my contribution centers around is that Bengson’s answer cannot be the end of the story. This is because, as Bar Luzon and Preston Werner have recently pointed (...) out, this answer leads to the follow-up question of why certain intuitional experiences are constituted by the facts, but others are not. My objective is to answer this question by specifying precisely what is epistemically defective about intellectual hallucinations. My result is that, in stark contrast to perception, intellectual hallucinations are epistemically defective in the sense that something is overlooked. In successful intuition, by contrast, all relevant possibilities/scenarios are considered/imagined. This has crucial epistemological implications. In particular, I argue that intuitions exhibiting a certain phenomenology cannot fail to successfully grasp abstract facts. I call this the non-accidental correctness thesis, which constitutes the main thesis of this paper. (shrink)

Solar radiation management (SRM) may help to reduce the negative outcomes of climate change by minimising or reversing global warming. However, many express the worry that SRM may pose a moral hazard, i.e., that information about SRM may lead to a reduction in climate change mitigation efforts. In this paper, we report a large-scale preregistered, money-incentivised, online experiment with a representative US sample (N = 2284). We compare actual behaviour (donations to climate change charities and clicks on climate change petition (...) links) as well as stated preferences (support for a carbon tax and self-reported intentions to reduce emissions) between participants who receive information about SRM with two control groups (a salience control that includes information about climate change generally and a content control that includes information about a different topic). Behavioural choices are made with an earned real-money endowment, and stated preference responses are incentivised via the Bayesian Truth Serum. We fail to find a significant impact of receiving information about SRM and, based on equivalence tests, we provide evidence in favour of the absence of a meaningfully large effect. Our results thus provide evidence for the claim that there is no detectable moral hazard with respect to SRM. [Open access]. (shrink)

In current debates, many philosophers of science have sympathies for the project of introducing a new approach to the scientific realism debate that forges a middle way between traditional forms of scientific realism and anti-realism. One promising approach is perspectivism. Although different proponents of perspectivism differ in their respective characterizations of perspectivism, the common idea is that scientific knowledge is necessarily partial and incomplete. Perspectivism is a new position in current debates but it does have its forerunners. Figures that are (...) typically mentioned in this context include Dewey, Feyerabend, Leibniz, Kant, Kuhn, and Putnam. Interestingly, to my knowledge, there exists no work that discusses similarities to the phenomenological tradition. This is surprising because here one can find systematically similar ideas and even a very similar terminology. It is startling because early modern physics was noticeably influenced by phenomenological ideas. And it is unfortunate because the analysis of perspectival approaches in the phenomenological tradition can help us to achieve a more nuanced understanding of different forms of perspectivism. The main objective of this paper is to show that in the phenomenological tradition one finds a well-elaborated philosophy of science that shares important similarities with current versions of perspectivism. Engaging with the phenomenological tradition is also of systematic value since it helps us to gain a better understanding of the distinctive claims of perspectivism and to distinguish various grades of perspectivism. (shrink)

A collection of essays investigating key historical and scientific questions relating to the concept of natural purpose in Kant's philosophy of biology.

Des premiers rites baptismaux à la confession moderne, les références au christianisme sont constantes dans l'œuvre de Michel Foucault. Cette constance s'inscrit dans un questionnement philosophique plus large sur notre actualité : comprendre le rapport que nous avons aujourd'hui à nous-mêmes demande de s'interroger sur les actes de vérité que l'Occident a instaurés depuis les premiers siècles chrétiens. Que faut-il dire et manifester de soi pour être transformé dans son être, pardonné, sauvé, jugé ou guéri)? Ce livre propose une étude (...) critique de l'ensemble des lectures chrétiennes de Foucault, avec une attention particulière portée au cours Du gouvernement des vivants. Ni chronologique ni thématique, le parcours suivi espère retrouver la logique d'un travail à la fois philosophique et historique : quand et comment le christianisme a-t-il été constitué par Foucault en objet de recherche, avec quelles pratiques de lecture et quelles conséquences sur l'interprétation)? (shrink)

Quelle politique peut-on faire quand on est un idiot? Loin d'être saugrenue, c'est bien la question qu'on est conduit à se poser inévitablement en lisant l'oeuvre de Gilles Deleuze. L'"idiot" joue, en effet, un rôle incontournable et essentiel dans la philosophie de Deleuze. Il est le personnage conceptuel qui fait tenir cette philosophie dans sa consistance propre. Il se situe à la charnière de l'image de la pensée que le philosophe invoque et suppose plus ou moins implicitement et de la (...) création de concepts qu'il produit explicitement. Aussi, faire de la philosophie, tout comme agir et penser politiquement, c'est toujours une manière de faire l'idiot. Les conséquences de cette approche sont capitales, du fait des questions posées à la réflexion politique classique centrée sur le Droit et l'Etat, du fait aussi des problématiques qui se voient invalidées dans ce champ. La place qui revient au contrôle et au bio-pouvoir, aux zones d'indétermination et aux espaces lisses, permet de prendre une saine distance vis-à-vis de la politique "majoritaire" et de faire apparaître, comme déjà de vieux clichés, bon nombre de thèmes et de concepts revendiqués par les organisations alternatives, mondialistes et subversives récentes. C'est une tout autre idée de la politique, centrée sur les devenirs, que nous invite à méditer la politique deleuzienne de l'idiot. Elle nous ouvre à d'autres espérances, nouvelles, en lien avec un "peuple absent" qui naîtrait avec chaque devenir. (shrink)

Animal research suggests that central serotonergic neurons are involved in behavioral suppression, particularly anxiety-related inhibition. The hypothesis linking decreased serotonin transmission to reduced anxiety as the mechanism in the anxiolytic activity of benzodiazepines conflicts with most clinical observations. Serotonin antagonists show no marked capacity to alleviate anxiety. On the other hand, clinical signs of reduced serotonergic transmission (low 5-HIAA levels in the cerebrospinal fluid) are frequently associated with aggressiveness, suicide attempts, and increased anxiety. The target article attempts to reconcile such (...) human and animal findings by investigating whether anxiety reduction or increased impulsivity is more Likely to account for animal behavioral changes associated with decreased serotonergic transmission. The effects of manipulating central serotonin in experimental anxiety paradigms in animals (punishment, extinction, novelty) are reviewed and compared with the effects of antianxiety drugs. Anxiety seems neither necessary nor sufficient to induce control by serotonergic neurons on behavior. Further evidence suggests that behavioral effects of anxiolytics thought to be mediated by decreases in anxiety are not caused by the ability of these drugs to reduce serotonin transmission. Blockade of serotonin transmission, especially at the level of the substantia nigra, results in a shift of behavior toward facilitation of responding. This behavioral shift is particularly marked when there is competition between acting and restraining response tendencies and when obstacles prevent the immediate attainment of an anticipated reward. It is proposed that serotonergic neurons are involved not only in behavioral arousal but also in enabling the organism to arrange or tolerate delay before acting. Decreases in serotonin transmission seem to be associated with the increased performance of behaviors that are usually suppressed, though not necessarily because of the alleviation of anxiety, which might contribute to the suppression. (shrink)

This chapter contains section titled: I The Extended Auction II Working in the Peep Show, Flirting in the Square III Insurance Behind a Veil of Ignorance IV Dworkin's Hybrid Scheme V Four Objections to Dworkin VI Ackerman Generalized VII Not Enough Redistribution? VIII Too Much Redistribution? Acknowledgement.

The conception of social justice presented and defended in Philippe Van Parijs, "Real Freedom for All" entails, among other implication, the justification of an unconditional basic income. It was the subject of seven critical comments that forms issue 22 and part of 23 of ANALYSE & KRITIK. In this article, Van Parijs offers a comprehensive reply.

An introduction to semantics for the general reader. How things mean, from animal communication to music.

Philipp Mayring und Norbert Rath greifen zentrale Fragen der heutigen Zeit auf: Was ist Glück? Woher kommt Glück? Wie kann man Glück erreichen? Zunächst geht es um klassische philosophische Ansätze – was verstehen antike Denker wie Demokrit, Platon, Aristoteles und Epikur sowie neuzeitliche Philosophen wie Montaigne, Kant, Hegel, Nietzsche, Freud und Adorno darunter? Es zeigt sich die Historizität der Glückskonzepte und die Notwendigkeit einer Kritik am »falschen« Glück. Psychologische Konzepte von Glück sind ebenso schillernd. Sie untersuchen empirisch, wie subjektive Glücksgefühle (...) zustande kommen, welche emotionalen, kognitiven und handlungsbezogenen Prozesse ihnen zu Grunde liegen und in welchen Situationen sich Menschen glücklich fühlen. Auch hier erscheint ein kritischer Standpunkt notwendig: Kritik an unterschiedlichen Glücksdefinitionen, Kritik an Erhebungsinstrumenten und Kritik an der Instrumentalisierung und Kommerzialisierung von Forschungsergebnissen. Gerade im Blick auf eine neuerdings weit verbreitete Positive Psychologie besteht ein Ideologieverdacht: Könnte es sich hier um kaum einlösbare Versprechungen einer affirmativen psychologischen Glücksforschung handeln? Philipp Mayring und Norbert Rath gehen diesen Fragen im Dialog zwischen Philosophie und Psychologie nach. Trotz der unterschiedlichen Herangehensweisen und Perspektiven der beiden Autoren zeigen sich erstaunliche Übereinstimmungen hinsichtlich einer kritischen Theorie des Glücks. (shrink)

Peut-on définir un "sens" musical? Quelle est la part d'intuition, de spontanéité, et celle de la technique, des règles, des systèmes dans la création? Pionnier de la musique électroacoustique en temps réel, Philippe Manoury nous fait entrer au coeur du processus de composition, montrant par exemple comment faire interagir les techniques numériques et les instruments acoustiques (y compris la voix) pour créer de nouvelles formes musicales et interroger sans cesse la matière sonore elle-même."--Page 4 of cover.

This chapter introduces time travel into the Star Wars lore. Time travel stories in which the past is changed are in danger of being inconsistent or plagued by paradoxes. In famous time travel stories such as Back to the Future, the protagonist travels to the past, changes the past, and then returns to a present quite different from the one they left. In contemporary philosophy of time, there are three main approaches to this question: presentism, eternalism, and the growing block (...) universe. Time travel works by entering a place, the World Between Worlds, that connects different points in time and space. In terms of modern physics, the portals in the World Between Worlds may be understood as traversable wormholes. The nature of time and the possibility of time travel have attracted and captivated humanity for centuries. (shrink)