According to the shared signal hypothesis the impact of facial expressions on emotion processing partially depends on whether the gaze is directed toward or away from the observer. In autism spectrum disorder several aspects of face processing have been found to be atypical, including attention to eye gaze and the identification of emotional expressions. However, there is little research on how gaze direction affects emotional expression processing in typically developing individuals and in those with ASD. This question is investigated here (...) in two multimodal experiments. Experiment 1 required processing eye gaze direction while faces differed in emotional expression. Forty-seven children participated. Their Autism Diagnostic Observation Schedule scores ranged from 0 to 6 in the experiment. Event-related potentials were sensitive to gaze direction and emotion, but emotion processing did not depend on gaze direction. However, for angry faces the gaze direction effect on the N170 amplitude, as typically observed in TD individuals, diminished with increasing ADOS score. For neutral expressions this correlation was not significant. Experiment 2 required explicit emotion classifications in a facial emotion composite task while eye gaze was manipulated incidentally. A group of 22 children with ASD was compared to a propensity score-matched group of TD children. The same comparison was carried out for a subgroup of nine children with ASD who were less trained in social cognition, according to clinician’s report. The ASD group performed overall worse in emotion recognition than the TD group, independently of emotion or gaze direction. However, for disgust expressions, eye tracking data revealed that TD children fixated relatively longer on the eyes of the stimulus face with a direct gaze as compared with averted gaze. In children with ASD we observed no such modulation of fixation behavior as a function of gaze direction. Overall, the present findings from ERPs and eye tracking confirm the hypothesis of an impaired sensitivity to gaze direction in children with ASD or elevated autistic traits, at least for specific emotions. Therefore, we conclude that multimodal investigations of the interaction between emotional processing and stimulus gaze direction are promising to understand the characteristics of individuals differing along the autism trait dimension. (shrink)

Guang Yangs Arbeit nimmt die zentrale Frage des heideggerschen Denkens nach dem Wesen des Logos und der Sprache wieder auf, verbindet sie aber mit dem Begriff der Dynamis. So erweist sich der Logos als diejenige Kraft, die zwischen Bewegung und Ruhe vermitteln und damit die Bewegtheit des Seins in sich versammeln kann. Mit dieser in sich gesammelten Kraft hängt auch das Phänomen der Ruhe zusammen, welches die Bewegung auffängt und entsprechend aufgewertet werden muss. Dieser in der Heidegger-Forschung selten beachtete (...) Gedanke der Ruhe deutet auf die privative Dimension des Seins hin, die auch bei Phänomenen wie räumlicher Leere und der Stille zum Tragen kommt und dabei nicht negativ zu fassen ist. In dieser Untersuchung wird zudem - mit und gegen Heidegger - der Möglichkeitscharakter des Seins hervorgehoben, der nicht allein in der vollzugshaften Bewegung aufgeht. (shrink)

Recently, Frauchiger and Renner proposed a Gedankenexperiment, which was claimed to be able to prove that quantum theory cannot consistently describe the use of itself. Here we show that the conclusions of Frauchiger and Renner actually came from their incorrect description of some quantum states. With the correct description there will be no inconsistent results, no matter which quantum interpretation theory is used. Especially, the Copenhagen interpretation can satisfy all the three assumptions,, and of Frauchiger and Renner simultaneously, thus it (...) has no problem consistently describing the use of itself. (shrink)

Ferroptosis, a form of regulated cell death triggered by lipid hydroperoxide accumulation, has an important role in a variety of diseases and pathological conditions, such as cancer. Targeting ferroptosis is emerging as a promising means of therapeutic intervention in cancer treatment. Polyunsaturated fatty acids, reactive oxygen species, and labile iron constitute the major underlying triggers for ferroptosis. Other regulators of ferroptosis have also been discovered recently, among them the mechanistic target of rapamycin complex 1 (mTORC1), a central controller of cell (...) growth and metabolism. Inhibitors of mTORC1 have been used in treating diverse diseases, including cancer. In this review, we discuss recent findings linking mTORC1 to ferroptosis, dissect mechanisms underlying the establishment of mTORC1 as a key ferroptosis modulator, and highlight the potential of co‐targeting mTORC1 and ferroptosis in cancer treatment. This review will provide valuable insights for future investigations of ferroptosis and mTORC1 in fundamental biology and cancer therapy. (shrink)

v. 1. Li ze xue -- v. 2. Yu zhou lun xin li xue -- v. 3 Xing shang xue.

本书从生态文艺的基本观念到历史扫描,进而比较宏观地把握中国美学中的生态思想及中国古代艺术中生态性体验的特点,并由此通过对中国古代美学与艺术的生态特点的认识,通过对其理论及审美转换性的把握而引申至现代, 着力挖掘其现代意义及价值。.

We give a general proof showing that if the evolution from one state to another is not reversible, then the projective measurements on the superposition of these two states are impossible. Applying this no-go result to the Schrödinger’s cat paradox implies that if something is claimed to be a real Schrödinger’s cat, there will be no measurable difference between it and a trivial classical mixture of ordinary cats in any physically implementable process, unless raising the dead becomes reality. Other similar (...) macroscopic quantum superpositions cannot be observed either, due to the lack of non-commuting measurement bases. Our proof does not involve any quantum interpretation theory and hypothesis. (shrink)

本书集中了当今学术界马一浮研究与近现代思想学术史的专家,从各个角度对马一浮学术思想与生平活动予以述介与阐发。.

本书包括两类:一类是从各个不同角度研究王阳明的生平事迹与思想学说,评论其学说宗旨、思想性质与历史影响的论文;另一类则主要是探讨阳明后学各家各派对阳明心学的继承、丰富、修正、扬弃的演变轨迹与思想特色.

Solid-state processing of metal material is a very complex physical and chemical process, which is coupled by a series of variations including heat transfer, momentum transfer, mass transfer, and phase change. Applying three-dimensional finite element numerical method to the simulation of solid-state processing can perform analysis of metal material’s forging processes before production trial production, can obtain their relevant information such as material flow law, temperature field, and strain field under the minimum physical test conditions, thereby predicting metal material’s forming (...) defects and improving their forging quality. On the basis of summarizing and analyzing previous research works, this paper expounded the current status and significance of solid-state processing of metal materials, elaborated the development background, current status, and future challenges of 3D finite element numerical simulation, introduced the discrimination method and free surface solution method of numerical simulation calculation, conducted finite element model’s geometric assumptions, material selection, element division, model establishment, parameter selection, and initial and boundary condition determination, and simulated and analyzed rheological casting, remelting heating, thixoforming, and rotary piercing processes of metal materials. The results show that the 3D finite element numerical method can not only simulate various processes of flow field, temperature field, stress field, and microstructure in solid-state processing but also can provide a reliable basis for effectively obtaining a reasonable description and finding a more optimized design plan for metal material processing in a short time, which plays an important role in understanding and analyzing solid metal forming process, controlling and optimizing process parameters, guiding and mastering rheological casting, and secondary heating and rotary piercing of metal materials. (shrink)

Social Information Science (or Social Informatics) is a new and interdiscipline branch subject in China. This paper probe the emergence and the research outline of social information science. 1. The proposal of the social information science. We set up the research from an extension from the theoretical informatics to the concrete informatics; a internal bond of integrating various subjects in humane and social sciences; an intersection and mutual permeation between the social science and the natural science; a the intersection and (...) interaction among humane and social sciences, modern information science and information technology; a strengthening to the research into Social Epistemology. Ⅱ. On the concept of social information. Social information directly is different with selfexistent and natural information, and more related to human’s autonomous creative activities, to society’s culture inheritance, to social value, to human’s spiritual interaction and to human’s emotions. Ⅲ.On the theoretical orientation of the social information science. Social Information Science is a concrete branch of informatics, a generation of sub-disciplines of social information, a kind of traversing and comprehensive research on individual social science from the angle of information, a kind of exchange and interaction between social theoretical research and the modern information technology. Ⅳ. The research focus of the social information science. The paper lists 10 main focus in the research of social information science. Ⅴ.The system and frame of the social information science. In general, there should be four levels of researches if the social information science is to be viewed as a relatively independent subject: the philosophical level, the scientific theoretical level, concrete apply level, social information technology and methods. (shrink)