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  1. Diagrams as Locality Aids for Explanation and Model Construction in Cell Biology.Nicholaos Jones & Olaf Wolkenhauer - 2012 - Biology and Philosophy 27 (5):705-721.
    Using as case studies two early diagrams that represent mechanisms of the cell division cycle, we aim to extend prior philosophical analyses of the roles of diagrams in scientific reasoning, and specifically their role in biological reasoning. The diagrams we discuss are, in practice, integral and indispensible elements of reasoning from experimental data about the cell division cycle to mathematical models of the cycle’s molecular mechanisms. In accordance with prior analyses, the diagrams provide functional explanations of the cell cycle and (...)
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    Tracing Organizing Principles: Learning From the History of Systems Biology.Sara Green & Olaf Wolkenhauer - 2013 - History and Philosophy of the Life Sciences 35 (4):553-576.
    With the emergence of systems biology the notion of organizing principles is being highlighted as a key research aim. Researchers attempt to ‘reverse engineer’ the functional organization of biological systems using methodologies from mathematics, engineering and computer science while taking advantage of data produced by new experimental techniques. While systems biology is a relatively new approach, the quest for general principles of biological organization dates back to systems theoretic approaches in early and mid-20th century. The aim of this paper is (...)
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    The Quest for System-Theoretical Medicine in the COVID-19 Era.Felix Tretter, Olaf Wolkenhauer, Michael Meyer-Hermann, Johannes W. Dietrich, Sara Green, James Marcum & Wolfram Weckwerth - 2021 - Frontiers in Medicine 8:640974.
    Precision medicine and molecular systems medicine (MSM) are highly utilized and successful approaches to improve understanding, diagnosis, and treatment of many diseases from bench-to-bedside. Especially in the COVID-19 pandemic, molecular techniques and biotechnological innovation have proven to be of utmost importance for rapid developments in disease diagnostics and treatment, including DNA and RNA sequencing technology, treatment with drugs and natural products and vaccine development. The COVID-19 crisis, however, has also demonstrated the need for systemic thinking and transdisciplinarity and the limits (...)
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    Interdisciplinarity as Both Necessity and Hurdle for Progress in the Life Sciences.Olaf Wolkenhauer & Jan-Hendrik Hofmeyr - 2013 - In Hanne Andersen, Dennis Dieks, Wenceslao González, Thomas Uebel & Gregory Wheeler (eds.), New Challenges to Philosophy of Science. Springer Verlag. pp. 225--235.
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    22 Mehrebenensysteme in der Biomedizin.Olaf Wolkenhauer & Tom Theile - 2015 - In Ivor Nissen & Bernhard Thalheim (eds.), Wissenschaft Und Kunst der Modellierung: Kieler Zugang Zur Definition, Nutzung Und Zukunft. De Gruyter. pp. 455-474.
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