DNA microarrays are perfectly suited for comparing gene expression in different populations of cells. An important application of microarray techniques is identifying genes which are activated by a particular drug of interest. This process will allow biologists to identify therapies targeted to particular diseases, and, eventually, to gain more knowledge about the biological processes in organisms. Such an application is described in this paper. It is focused on diabetes and obesity, which is a genetically heterogeneous disease, meaning that multiple defective (...) genes are responsible for the diseases. The paper is divided in three parts, each dealing with a different problem addressed to our study. First we validate the data from our microarray experiment. We identified significant systematic sources of variability which are potentially issues for other microarray datasets. Second, we applied multiple hypothesis testing to identify differentially expressed genes. We found a set of genes which appear to change in expression level over time in response to a drug treatment. Third, we tried to address the problem of identification of co-expressed genes using cluster analysis. This last problem is still under discussion. (shrink)

Recent research explores the high proliferation of conspiracy theories about COVID-19 vaccination, and their potential effects within digital media environments. By means of a 2 × 2 experimental design (N = 945) conducted in Romania, we explore whether exposure to media messages promoting conspiracy theories about vaccination versus media messages debunking such conspiracy narratives could influence people’s intention to either support or argue against vaccination in front of their friends and family (interpersonal influence). We also analyze the moderation effects of (...) education and critical thinking. Main results show that both conspiracy and counter-conspiracy media content about vaccination negatively affect people’s willingness to discuss the topic with others, which offers support for a silencing effect. Education and critical thinking moderate the main effects, but only to some extent and in certain experimental conditions. (shrink)

Economic diplomacy is known as a symbol of the European Union and represents its primary function. With the development of science and new ways of communication, the European Union can organize a new approach for its economic diplomacy. The main advantage of the European Union as a soft power is that its economic and diplomatic interests are represented in a manner that is based not on confrontation but economic collaboration with other states. The disadvantage is that this domain is presently (...) not used enough to represent EU interests. This paper describes economic diplomacy in general and the economic diplomacy of the EU in particular. Divided into three parts, the goal of this study is to outline the importance of economic diplomacy, its evolution, the influence of this domain on the creation of previous economic treaties, and its possible future impact on the development of new agreements between the European Union and its neighbor countries. The main methodology used is descriptive, presenting the evolution of this field and the new business strategies that can be used to improve cooperation at the eastern border of the European Union. Therefore we present here the historical background of EU economic diplomacy, its present issues and future challenges. The quantitative data used in this research paper are based on information from EU websites and on the actual events concerning debates about economic diplomacy and its future. The research questions presented herein follow the general evolution of this domain and its mutual influence with EU’s businesses strategies. (shrink)

In contrast with the progressive dilution of religions predicted by traditional liberal and Marxist approaches, religions remain important for many people, even in Europe, the most secularised continent. In the context of increasingly culturally diverse societies, this calls for a reinterpretation of the secular legacy of the Enlightenment and also for an updating of democratic institutions. This book focuses on a central question: are the classical secularist arrangements well equipped to tackle the challenge of fast-growing religious pluralism? Or should we (...) move to new post-secular arrangements when dealing with pluralism in Europe? Offering an interdisciplinary approach that combines political theory and legal analysis, the authors tackle two interrelated facets of this controversial question. They begin by exploring the theoretical perspective, asking what post-secularism is and looking at its relation to secularism. The practical consequences of this debate are then examined, focusing on case-law through four empirical case studies. This book will be of interest to students and scholars of political theory, philosophy, religion and politics, European law, human rights, legal theory and socio-legal studies. (shrink)

Cette étude se propose d’envisager les effets du mouvement husserlien de génétisation de l’ego pur transcendantal sur l’identité de cet ego même. L’habitus, la passivité , l’instinct sont les moments génétiques qu’augmentent la tension entre la facticité et la transcendantalité de l’auto-constitution de l’ego. L’identité semble échapper à tout acte d’identification pour s’enfouir dans dans la vie même de l’ego.

The young generation of the ’80s was born and entirely educated under communist ideology. And yet indoctrination failed for some of these young people, who saw the West as a symbol of a better society to aspire to. In order to escape from S.R. Romania, some of them risked their lives in the “adventure” of crossing the border illegally. The main opponents of the fugitives, the border guards, were part of the same age group. In many cases, they behaved brutally (...) toward the fugitives. Did they come to see them as traitors, or was it just the context in which this adversity manifested itself mixed with the soldiers’ fear of their superiors’ punishments? The study is part of a more extensive research regarding the phenomenon of illegal border crossing during Ceaușescu`s dictatorship. Through this study, I aim to analyse the two situations in which some of the young people of the ’80s could find themselves: opponents of the regime (when fleeing to the West was a form of protest) and involuntary “servants” of the system, such as border soldiers, respectively. Also, I focused on identifying the reasons for the conflict between the two categories of young people belonging to the same generation. (shrink)

What is the place of religion in a pluralist democracy? The continuous presence of religion in the public sphere has raised anew normative and practical issues related to the role of religion in a democratic polity, generating spirited political debates in Western and non-Western contexts. Contemporary Political Philosophy and Religion provides an advanced introduction to, and a critical appraisal of, the major schools of political thought with a focus on the relationship between democracy and religion. Key features of this book (...) include: -/- - Analyses of different political traditions: liberalism, republicanism, deliberative democracy, feminism, postmodernism, multiculturalism, and interculturalism; -/- - Critical discussions of key contemporary philosophers, such as John Rawls, Jürgen Habermas, Richard Rorty, Charles Taylor, Susan Moller Okin, Martha Nussbaum, Will Kymlicka, Chandran Kukathas, and Bhiku Parekh; -/- - A pluralist approach that questions the strict divide between analytical and continental political philosophy; -/- - Discussion on the place of religion in politics from multiple perspectives by drawing on a plurality of political contexts, both Western and non-Western; -/- - Analyses of legal and political cases related to different religious traditions, for example, Islam, Confucianism, Buddhism, Christianity, and Hinduism. -/- This comprehensive text will be of great use to students of religion and politics in the fields of political and legal theory, and religious and theological studies, while also offering critical insights and arguments that will be of interest to the experts in the field. (shrink)

The religious landscape in Europe is changing dramatically. While the authority of institutional religion has weakened, a growing number of people now desire individualized religious and spiritual experiences, finding the self-complacency of secularism unfulfilling. The "crisis of religion" is itself a form of religious life. A sense of complex, subterraneous interaction between religious, heterodox, secular and atheistic experiences has thus emerged, which makes the phenomenon all the more fascinating to study, and this is what Religion in Contemporary European Cinema does. (...) The book explores the mutual influences, structural analogies, shared dilemmas, as well as the historical roots of such a "post-secular constellation" as seen through the lens of European cinema. Bringing together scholars from film theory and political science, ethics and philosophy of religion, philosophy of film and theology, this volume casts new light on the relationship between the religious and secular experience after the death of the death of God. (shrink)

The interest in data anonymization is exponentially growing, motivated by the will of the governments to open their data. The main challenge of data anonymization is to find a balance between data utility and the amount of disclosure risk. One of the most known frameworks of data anonymization is k-anonymity, this method assumes that a dataset is anonymous if and only if for each element of the dataset, there exist at least k − 1 elements identical to it. In this (...) paper, we propose two techniques to achieve k-anonymity through microaggregation: k-CMVM and Constrained-CMVM. Both, use topological collaborative clustering to obtain k-anonymous data. The first one determines the k levels automatically and the second defines it by exploration. We also improved the results of these two approaches by using pLVQ2 as a weighted vector quantization method. The four methods proposed were proven to be efficient using two data utility measures, the separability utility and the structural utility. The experimental results have shown a very promising performance. (shrink)

Dentro del mundo tan complejo, las sociedades tan diversas que lo componen y la situación tan delicada que las personas junto a la naturaleza están viviendo, actualmente, la creatividad y su aplicación en todos los ámbitos, y más en la construcción de la paz, es un claro desafío para la sociedad del siglo XXI. En este contexto, el monográfico La creatividad en la filosofía para hacer las paces: Nuevos horizontes interdisciplinarios es una recopilación de nueve artículos en los que autores (...) y doctores internacionales han reflexionado sobre la importancia de la creatividad en la construcción de la cultura de paz, cada uno y cada una de ellas enfocando su teoría hacía ejemplos de edificación creactiva que parten de problemas cotidianos. Son aportaciones que abogan por una creatividad como competencia de dar un paso más para superar lo ordinario, yendo más allá de lo familiar y de lo habituado, orientando siempre la mirada hacia la paz. En estos casos se debe hablar de la voluntad de arriesgar y de la motivación impulsada por la pasión, como motores para el devenir creativo y constructor. (shrink)

The Covid-19 pandemic is a global threat that affects a large part of the population, but the risks associated with it are higher for some people compared with others. Previous studies show that lower socioeconomic status is associated with more chronic stress and less marital satisfaction. Thus, the uncertainty caused by the pandemic might greatly affect those who were already vulnerable. This longitudinal study explores the extent to which stress originated outside and inside the relationship is associated with marital satisfaction (...) during the Covid-19 pandemic and whether the associations are different based on the socioeconomic status of the participants. The study was conducted at two points in time with a sample of 144 married Romanian couples. We used the Actor-Partner Interdependence Model with Mediation and multi-group SEM analysis. Higher levels of external stress were associated with subsequent lower marital satisfaction for women with higher SES. For the couples with lower SES, men's level of internal stress during the first assessment mediated the relationship between their higher level of external stress at the first time point and their partner's lower marital satisfaction during the second assessment. Our results show that men and women respond differently during a crisis and that couples with lower SES are more prone to greater stress and lower levels of marital satisfaction. We finally suggest that the therapists, health professionals, policy makers, and researchers should take into account the existing vulnerabilities of a couple when offering psychological and health services during the Covid-19 pandemic. (shrink)

This paper tries to show that the naturalistic view of addiction is mired in contradictions that stem from reducing the addict to a weak-willed subject who loses control over his or her body. From a phenomenological perspective, addiction reveals itself to be a habit which eventually becomes harmful, but has its primary sources in the embodied needs of a worldly subject. The aim of this paper is to uncover the dimensions of the lived addiction that are neglected in the contemporary (...) naturalistic discourse: the lived-body and the worldly context of the addict. Firstly, we try to do justice to the variety of addictions by underlying that their new and surprising forms are determined by the intersubjective tissue wherein the subject operates. Secondly, the loss of control in addiction, how the subject deals with the tendency to satisfy a need, is experienced as powerlessness, as expressed in the accounts of ecstasy addicts regarding altered states of mind. The last section of this paper will argue that this sense of powerlessness cannot be equated with a weakness of the will because a strong, forceful will engenders the same vertigo of being prey to strange powers. The embodied aspect of addiction and the spontaneous, bodily need it saturates will clarify further this claim. (shrink)

This essay explores both the appeal and the difficulties of Derrida’s “democratic Romanticism.” Derrida’s broader philosophical project seeks to make explicit the paradoxes or aporias that are embedded in practical experience. In unveiling these aporias, Derrida pleads, particularly in his later writings, for a transformation of democracy and religion so as to make them hospitable to difference. However, I will argue that Derrida’s reduction of the great variety of moral-political and religious situations to one aporetic logic runs into conceptual problems (...) and risks undoing the moral tissue that makes hospitality possible in the first place. (shrink)

IntroductionIn the coronavirus disease 2019 pandemic, Romanian universities switched to emergency relocation and online education, with students experiencing a sense of isolation, which affected their well-being, pace and normal learning style, relationships with other colleagues, and Professors. Beyond the technological obstacles that have arisen in learning, the aim of this study is to highlight the psychological variables that are associated and that explain the self-perceived well-being of students, in university, in the pandemic. The psychological variables studied were the following: the (...) level of openness and personal autonomy, as personality traits of students but also the mechanisms for regulating their academic motivation.MethodWe used a questionnaire-based survey, wherein all four research instruments had been validated and adapted to the investigated population. The subjects were BA and MA students at the University of Oradea, Romania, the majority being females with the age range of 27 years old. Pearson Correlation and Multiple Linear Regression were used to test the two hypotheses.ResultsResearch data obtained in the correlation analysis, point out association relationships with moderate and high effects size, between positive attitude toward self, others and student life and: openness to learning, openness to aesthetics, behavioral autonomy, cognitive autonomy, intrinsic motivation, and identification motivation. Furthermore, in regression analysis, it was revealed that regarding the variance of results concerning students’ self-perceived well-being in university, it contributes both of students’ personality traits and their intrinsic motivation and identification motivation.ConclusionThe fundamental conclusion of the research is that, although the personality traits of students explain in a higher percentage the variability of results in students’ self-perceived well-being, motivation regulation mechanisms play an important role, especially in the conditions of online activities. The results have direct implications for the work carried out in universities. The educational policies developed by specialists and government will have to emphasize the ways of forming resilient student communities in periods of sudden transition and adaptation to change which take place in education and society. (shrink)

This study examined the influence of the executive board of directors’ gender diversity on the financial performance of listed companies on the Bucharest Stock Exchange, for the period 2011 to 2019. The analysis of the composition and different characteristics of the board and the executive directors proved to be effective tools for corporate governance in countries with an emerging capital market. Therefore, a disclosure index on directors’ characteristics was used to moderate the interaction between gender diversity and financial performance, based (...) on the theoretical framework provided by upper echelon theory. The study contributes to the enrichment of the literature both by using the composite indicator built by applying the multiway PCA method on panel data to express financial performance and by designing the ten EGLS panel models involving five financial indicators and two proxies for gender diversity. The results showed that there is a positive impact of the proportion of women on the executive board of directors on financial performance, measured through the composite index, ROA, ROE, and SOL. A statistically significant impact of gender diversity on financial performance was found only for SOL, in the case of the Blau index. Also, using the random-effects model to perform the panel data analysis, the results showed that a higher executive board size can be associated with better financial performance measured through the composite index, ROA, ROE, and EPS. Practical implications are significant for the board of executives’ composition, the complexity of the relationship with the board, and reshaping governance practices. (shrink)

Cinema has a long history of engaging with the theme of sacrifice. Given its capacity to stimulate the imagination and resonate across a wide spectrum of human experiences, sacrifice has always attracted filmmakers. It is on screen that the new grand narratives are sketched, the new myths rehearsed, and the old ones recycled. Sacrifice can provide stories of loss and mourning, betrayal and redemption, death and renewal, destruction and re-creation, apocalypses and the birth of new worlds. The contributors to this (...) volume are not just scholars of film but also students of religion and literature, philosophers, ethicists, and political scientists, thus offering a comprehensive and interdisciplinary approach to the relationship between cinema and sacrifice. They explore how cinema engages with sacrifice in its many forms and under different guises, and examine how the filmic constructions, reconstructions and misconstructions of sacrifice affect society, including its sacrificial practices. This book was originally published as a special issue of Angelaki: journal of the theoretical humanities. (shrink)

Historians of science and religion usually trace the origins of the “conflict thesis,” the notion that science and religion have been in perennial “conflict” or “warfare,” to the late nineteenth century, particularly to the narratives of New York chemist John William Draper and historian Andrew Dickson White. In this essay, I argue against that convention. Their narratives should not be read as stories to debunk, but rather as primary sources reflecting themes and changes in religious thought during the late nineteenth (...) century. I contend that Draper and White were part of a long liberal Protestant heritage that emphasized history, reason, and religious emancipation against ecclesiastical authority. As an alternative source of origins, however, I suggest that the real “conflict thesis” is to be found in the fledgling discipline of the history of science as it emerged during the late nineteenth and first half of the twentieth century. The real origin of the “conflict thesis” is found in the very discipline that now seeks to condemn it. (shrink)

The European Legacy, Volume 17, Issue 3, Page 417-418, June 2012.

The European Legacy, Volume 17, Issue 4, Page 553-554, July 2012.

Economic activities are always supposed to carry with them the risk of market. Our area of research is concerned with what is known as the model of risk decisions at the level of economic activity; a model that can be valuable at any point of economic development. In our research, we present important aspects of risk in taking decisions in the previous and current dynamics of the market. The conditions of taking decisions with potential risks provide decision-makers with the possibility (...) to analyze and calculate risk in order to know what can be gained and lost. In our paper, we present a short description of a different model of risk in economic activity and of decision-making risk, providing examples that have been offered by various authors. For example, Friedman and Savage present the utility function of an economic agent and its availability to accept the risk, while Markowitz defines utility in terms of winning or losing. Our paper starts with a presentation of the quantification of risk in economic activity. In the second part, we present a model of decision-making risk that is applied in economic activities and the difference between risk and uncertainty. (shrink)

:This article revisits Michael Haneke's Caché as a filmic transformation of the traditional bond between sacrificial violence, morality and community building. By drawing mainly on striking correspondences with Jacques Derrida's view of the “mystical” origin of authority and of the limits of moral representation, the article aims to probe into Haneke's strategies of concealment. In so doing, the article proposes a “postsecular” interpretation of the symbolic meaning of the enigmas of the “ghost director” within the film, and of Majid's theatrical (...) self-sacrifice. (shrink)

Place-based policies tackle grand socio-economic challenges through differentiated, context-sensitive interventions. However, they often run the risk of under- or mis-performing. This work studies how grand challenges translate from policy to cross-sector partnerships through place. By focusing on the place-based policy of regional smart specialization (RIS3), I investigate how the setup of science and technology parks mediates the practices of the actors in the translation chain: a transnational policymaker (macro), a regional broker (meso), and a local partnership which served as prototype (...) for the regional policy (micro level). I document two types of practices—emplacement and space configuration—enacted at each level, and show how their interplay transformed the grand challenge from a cautious ideal at the macro level which balances risk and responsibility, to an optimistic and risk-prone approach at the partnership level. The study contributes to the policy and cross-sector partnerships literatures by documenting a two-sided effect of place-based policy and a consequent risk of ethical reversal, from an early attractor bringing partners together to a later accomplice keeping the partners together despite evident signs of failure. By adopting a strong multimodal approach, I also distinguish four types of multimodal outcomes—ideal type, prototype, virtual model, and lived artifact—which perform the two-sided effect and bring about the risk of reversal. Practical implications include a redistribution of the burden of failure from the CSPs implementing the grand challenges to the institutional fields in which these are bred. (shrink)

Collective intelligence in organizational teams has been predominantly understood and explained in terms of the quality of the outcomes that the team produces. This manuscript aims to extend the understanding of CI in teams, by disentangling the core of actual collective intelligent team behavior that unfolds over time during a collaboration period. We posit that outcomes do support the presence of CI, but that collective intelligence itself resides in the interaction processes within the team. Teams behave collectively intelligent when the (...) collective behaviors during the collaboration period are in line with the requirements of the tasks the team is assigned to and the environment. This perspective results in a challenging, but promising research agenda armed with new research questions that call for unraveling longitudinal fine-grained interactional processes over time. We conclude with exploring methodological considerations that assist researchers to align concept and methodology. In sum, this manuscript proposes a more direct, thorough, and nuanced understanding of collective intelligence in teams, by disentangling micro-level team behaviors over the course of a collaboration period. With this in mind, the field of CI will get a more fine-grained understanding of what really happens at what point in time: when teams behave more or less intelligently. Additionally, when we understand collectively intelligent processes in teams, we can organize targeted interventions to improve or maintain collective intelligence in teams. (shrink)

In recent years, various European and UN documents have been advancing the idea of `open, transparent and regular' dialogue between religion and democracy. Is this the naïve rhetoric of the `Good European'? This article will discuss this issue starting from the debate between Habermas and Rawls on the role of religion in the public sphere. My approach presupposes a passage from deliberation to democratic rhetoric, the correlative abandonment of some of the tenets of Habermas's secularism, as well as a greater (...) concern with the question of the power asymmetries underpinning discursive exchanges. (shrink)

Islamism is a form of political and religious utopia, created by the Arab-Muslim world, as an ideological alternative to the invasion of modern western doctrines: communism, socialism, liberalism, capitalism etc. This political and ideological current appears to some as a substitute for nationalism, which lost its appealin many Muslim countries, due to the application of a „socialist" model, as well as due to the deception that emerges from the successive defeats in the fight with the Israeli enemy. The anti-Occidentalism of (...) this movement is seen as a side effect in the fight against laicization, against materialism and moral degradation. (shrink)

Review of Ronald Dworkin, Religion without God , (Harvard University Press, 2013), 180 pages.

“From Paideuma to Shari’a”. Paideuma, concept developed by Leo Frobenius at the beginning of the XXth century, seems to regain its proper actuality when we try to understand the Islamic civilization. Among the roots which define a paideuma, in the particular case of Islam we identified the shari’a as being the most significant one. Shari`a also brings with it a new dimension: the continuous extension of the paideuma, which overpasses frontiers and national identities. The famous sartrian expression “hell is the (...) other” may occur only if we don`t know the Other enough. (shrink)

Baudrillard interpreta el «nuevo terrorismo» como un intercambio simbólico de regalo y contra-regalo: la muerte del terrorista es un contra-regalo irrefutable que rompe el círculo coercitivo de las relaciones sociales «impuestas» por el sistema global. A su vez, la concepción de Derrida tiene dos dimensiones, explicativa y normativa: en primer lugar, Derrida considera el 11-S como un síntoma multifacético de una crisis autoinmune que tiene aspectos políticos, religiosos y tecno-capitalistas. En segundo lugar, Derrida arguye que existe un «momento» de terror, (...) violencia y sacrificio que es constitutivo en las decisiones y en la responsabilidad éticas. De forma crítica, argumentaré que la concepción de Baudrillard se basa en una noción extremada y partidista de un sistema que se interpreta como un inmenso mandato de un gobernante totalitario. Por su parte, Derrida convierte de forma innecesaria la observación de que las acciones humanas pueden tener consecuencias perversas en una ley de la autoinmumidad inspirada en la biología. Al considerar el terror como algo constitutivo incluso en las relaciones éticas más comunes, Derrida corre también el riesgo de convertir un fenómeno extremado en un concepto que lo abarca todo, y de perder contacto con la práctica ética corriente. Concluiré que las concepciones de Baudrillard y de Derrida sobre el terror y el terrorismo comparten un «gusto por lo extremado» que las hace en última instancia poco convincentes. (shrink)

I focus on Barry C. Smith’s investigations in the phenomenology of speech, and on his ambitious, unified theory of both sub-personal and first-personal linguistic knowledge (2008, 2009). I argue that empirical hypotheses about our awareness of word meaning challenge the starting points of his phenomenology of speech, as they require both (1) modifications of his proposed theory of speakers experiences of word meaning, and (2) clarifications of what the phenomenology of speech teaches us and why.

Historians of science and religion have given little attention to how historical‐critical scholarship influenced perceptions of the relationship between science and religion in the nineteenth century. However, the so‐called “cofounders” of the “conflict thesis,” the idea that science and religion are fundamentally and irrevocable at odds, were greatly affected by this literature. Indeed, in his two‐volume magnum opus, A History of the Warfare of Science with Theology in Christendom (1896), Andrew D. White, in his longest and final chapter of his (...) masterpiece, traced the development of the “scientific interpretation” of the Bible. In this article, I argue that developments in biblical criticism had a direct impact on how White constructed his historical understanding of the relationship between science and religion. By examining more carefully how biblical criticism played a significant role in the thought of White and other alleged cofounders of the conflict thesis, this article hopes to relocate the origins, development, and meaning of the science–religion debate at the end of the nineteenth century. (shrink)