Neil E. Williams develops a systematic metaphysics centred on the idea of powers, as a rival to neo-Humeanism, the dominant systematic metaphysics in philosophy today. Williams takes powers to be inherently causal properties and uses them as the foundation of his explanations of causation, persistence, laws, and modality.

Powers theorists frequently assert that their neo-Aristotelian frameworks are dynamic, and that this gives them a theoretical advantage over their neo-Humean rivals. But recently it’s been claimed that activity can also be used to divide powers theories themselves. Dynamism is here understood primarily in terms of activity: a metaphysic counts as dynamic according to the place activity is given within the system. Activists treat activity as fundamental or irreducible, and claim to have the philosophical high ground over those ‘passivist’ powers (...) theories wherein activity is reducible or nonfundamental. In this paper I take a closer look at dynamism within powers theories, with a particular focus on how the activism/passivism distinction might be made. I then consider the broader ontological impact that the various commitments to activity might carry, along with an assessment as to who appears to be better off. Despite what’s been claimed, I find no reason to think that activists have any serious theoretical advantage in this debate. In fact, as things presently stand, I am not convinced that powers and activity make for a good pairing at all, as there’s presently no good model for powers like this. (shrink)

I raise a puzzle case for “cluster” accounts of natural kinds—the homeostatic property cluster and stable property cluster accounts, especially—on the basis of their expected treatment of the metaphysics of certain disease kinds. Some kinds, I argue, fail to exhibit the co-instantiated property clusters these cluster views take to be constitutive of natural kinds. Some genetic diseases, for example, have archetypical instances with few or none of the pathological processes or symptoms associated with the kind: their instances are typified by (...) a single dispositional property. I dub such kinds ‘amorphic’, owing to their limited morphology, and try out a number of ways in which these kinds might be treated in terms of property clusters, adapting responses cluster theorists have offered to the problem of polymorphic species. Finding these responses wanting, I conclude that cluster accounts are unlikely to be the best account of the metaphysics of amorphic kinds. (shrink)

This paper offers an original solution to the problem of the many, built on a foundation of powers-based causation. At its most basic, the solution should be understood as a type of maximality response, and on those grounds its originality might be questioned. However, it is argued that novelty of the solution owes as much to the meta-metaphysical context in which the solution is framed as it does the model of causal powers. A discussion of paradigms in metaphysics is included.

Central to the debate between Humean and anti-Humean metaphysics is the question of whether dispositions can exist in the absence of categorical properties that ground them (that is, where the causal burden is shifted on to categorical properties on which the dispositions would therefore supervene). Dispositional essentialists claim that they can; categoricalists reject the possibility of such ?baseless? dispositions, requiring that all dispositions must ultimately have categorical bases. One popular argument, recently dubbed the ?Argument from Science?, has appeared in one (...) or another form over much of the last century and purports to win the day for the dispositional essentialist. Taking its cue from physical theory, the Argument from Science treats the exclusively dispositional characterizations of the fundamental particles one finds in physical theory as providing a key premise in what has been called a ?decisive? argument for baseless dispositions. Despite sharing the intuition that dispositions can be baseless, I argue that the force and significance of the Argument from Science have been greatly overestimated: no version of the argument is close to decisive, and only one version succeeds in scoring points against the categoricalist. Not only is physical theory more ontologically innocent than defenders of baseless dispositions seem to appreciate, most versions of the Argument from Science neglect important ways that dispositions could be grounded by categorical properties. (shrink)

Recently, several philosophers have defended what might be called `neo-essentialism' about natural kinds. Their views purport to improve upon the traditional essentialism of Kripke and Putnam by rejecting the claim that essences must be comprised of intrinsic properties. I argue that this so-called break from traditional essentialism is not a break at all, because the widespread interpretation of Putnam according to which he takes essences to be intrinsic is mistaken. Putnam makes no claim to the effect that essences of natural (...) kinds must be intrinsic, and offers at least one example of a natural kind whose essence is non-intrinsic. I conclude that his traditional essentialism has been misinterpreted, and consequently that neo-essentialism is not so `neo' after all. (shrink)

Power theorists are divided on the question of whether individual powers are single-track (for a single manifestation type) or are multi-track (capable of producing distinct manifestation types for distinct stimuli). EJ Lowe has recently defended single-tracking, arguing that the multi-tracker can provide no adequate reason for treating powers as capable of having multiple manifestation types, and claiming that putative instances of multi-track powers are either single-track powers in need of unifying descriptions or are merely several single-track powers. I respond to (...) Lowe on behalf of the multi-tracker, first by arguing that he overlooks the extra-empirical features of the debate, then by posing a dilemma for any single-track account of powers concerning the single-tracker’s ability to appropriately deal with fine-grained manifestation types. Finally I provide the aforementioned reason for thinking that there are multi-track powers. (shrink)

This chapter focuses on the view that diseases comprise natural kinds and how this view is in conflict with the essentialist picture of natural kinds as championed by Kripke and Putnam. This essentialist depiction of natural kinds contends that in order for a class of entities to be a natural kind, it is required that all and only members of the class instantiate very specific properties that explain the presence of any other properties typically associated with being a member of (...) the kind; these privileged properties constitute the “essence” of the kind. The problem is that the essentialist picture provides only two options, none of which is desirable: satisfy the essentialist desiderata by locating some etiological feature both necessary and sufficient for kind membership, or reject the thought that similarity between disease instances can be understood in terms of natural kinds. (shrink)

The aim of the paper is to give an ontologically informed account of disease that can aid in the construction of disease ontologies. The paper begins by distinguishing cases of diseases from what are purely structural abnormalities, referred to as ‘disorders’. The paper then presents a causal model apt for the understanding of disease that distinguishes diseases from both their causes and their potential effects. The analysis of disease defended treats disease in terms of distortions of standard cellular network processes, (...) where those distortions are incapable of self remedy and produce biologically disadvantageous symptoms. (shrink)

– The paper defends a naturalistic version of modal actualism according to which what is metaphysically possible is determined by dispositions found in the actual world. We argue that there is just one world—this one—and that all genuine possibilities are anchored by the dispositions exemplified in this world. This is the case regardless of whether or not those dispositions are manifested. As long as the possibility is one that would obtain were the relevant disposition manifested, it is a genuine possibility. (...) Furthermore, by starting from actual dispositional properties and branching out, we are able to include possibilities that are quite far removed from any state of affairs that happens to obtain, while still providing a natural and actual grounding of possibility. Stressing the importance of ontological considerations in any theory of possibility, it is argued that the account of possibility in terms of dispositional properties provides a more palatable ontology than those of its competitors. Coming at it from the other direction, the dispositional account of possibility also provides motivation for taking an ontology of dispositions more seriously. As well as the relevant dispositional notions required to lay out the view, the paper discusses the dispositional realism needed as the basis for the account of possibility. (shrink)

John Heil’s From an Ontological Point of View (Heil 2003) is a tremendous philosophical work. The neo-Lockean ontology the reader finds within its 267 pages is a sensible and refreshing alternative to the neo-Humean ontologies which presently occupy the vast majority of the metaphysical literature. What Heil offers is a much needed change in perspective. Nor are the strengths of the book limited to Heil’s willingness to approach central metaphysical problems in largely untried and unpopular way; the book is very (...) clear in its presentation, accessible to wide readership, and tightly argued throughout. Heil’s efforts in this book are to be applauded, and the result is one that warrants serious consideration by all those interested in serious metaphysics. But the interest should not end there: the lessons of Heil’s book are ones that almost all philosophers ought to take seriously. Despite the criticism that follows, my overall position should not be taken as anything short of a whole-hearted endorsement of Heil’s book. Nonetheless, when philosophy is one’s trade, there is always going to be something to disagree about, however much one is amenable to a view. (shrink)

1 Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2 During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for (...) generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3 The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4 The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5 Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible. (shrink)

With aims to both increase organ supply and better reflect individual donation preferences, many nations worldwide have shifted from ‘opt‐in’ to ‘opt‐out’ systems for post‐mortem organ donation (PMOD). In such countries, while a prospective donor's willingness to donate their organs/tissues for PMOD was previously ascertained—at least partially—by their having recorded positive donation preferences on an official register prior to death, this willingness is now presumed or inferred—at least partially—from their not having recorded an objection to PMOD—on an official organ donation (...) register. Using evidence regarding the presence and prevalence of selective donation preferences, and via exploration of how appeals to donation preferences are used to both motivate and legitimate shifts to opt‐out frameworks, this paper draws attention to a set of previously unexplored problems for opt‐out organ donation arising in contexts where: (a) individuals demonstrate selective post‐mortem organ/tissue donation preferences, (b) legislation provides prospective donors with the opportunity to selectively permit/refuse the donation of certain organs/tissues in line with these preferences. While selective preferences pose few problems for opt‐in systems where a selective occasion is built into the process of signing the donor register, this is not the case for opt‐out systems. The loss of this selective occasion can cause significant problems where appeals to preferences motivate/legitimate shifts to opt‐out but evidence regarding variable preferences does not feed into determinations regarding organ/tissue exclusions. The nature of these problems depends on how the authorization aspect of ‘opt‐out’ systems is framed (e.g. as presumed consent, deemed consent or, given the role of familial consent in many jurisdictions as consent in name only). (shrink)

Although psychologist impairment has received attention from researchers, there is a paucity of empirical data aimed at determining the point at which such impairment necessitates action. The purpose of this study was to provide such empirical data. Members of Division 42 (n = 285) responded to vignettes describing a psychologist whose symptoms of either depression or substance abuse varied across five levels of severity. Results identified specific levels of impairment at which psychologists were deemed too impaired to practice psychotherapy, as (...) well as significant differences between ratings of increasingly severe impairment. Practical and ethical implications of these results are discussed. (shrink)

Volume 34, Issue 8, December 2020, Page 1632-1645.

Environmental actions require a willingness to act, which, in turn, is stimulated partially by the belief that an action will yield the desired consequences. In determining whether an actor was justified in exerting the will to act, therefore, it is essential to examine the nature of evidence offered by the actor in support of any beliefs about the environment. In this paper we explore the points in environmental risk analyses at which evidence is brought to bear in support of inferences (...) conceming environmental effects of regulatory actions. The intent is to provide a framework for discussing the manner in which evidence may provide a sufficient basis for ethically sound decisions for environmental actions. (shrink)

Globalization generates new structures of human interdependence and vulnerability while also posing challenges for models of democracy rooted in territorially bounded states. The diverse phenomena of globalization have stimulated two relatively new branches of political theory: theoretical accounts of the possibilities of democracy beyond the state; and comparative political theory, which aims at bringing non-Western political thought into conversation with the Western traditions that remain dominant in the political theory academy. This article links these two theoretical responses to globalization by (...) showing how comparative political theory can contribute to the emergence of new global “publics” around the common fates that globalization forges across borders. Building on the pragmatist foundations of deliberative democratic theory, it makes a democratic case for comparative political theory as an architecture of translation that helps deliberative publics grow across boundaries of culture. (shrink)

This collection is a festschrift prepared for Williams on his retirement from the White’s Professorship of Moral Philosophy at Oxford. The topics covered include equality, consistency, comparison between science and ethics, integrity, moral reasons, the moral system, and moral knowledge. Most of the chapters combine exegetical and critical ambitions. With contributions by J. E. J. Altham, Jon Elster, Nicholas Jardine, Ross Harrison, Christopher Hookway, John McDowell, Martin Hollis, Martha Nussbaum, Amartya Sen, and Charles Taylor, and replies by Bernard (...) class='Hi'>Williams. (shrink)

Given a countable model of set theory, we study the structure of its generic multiverse, the collection of its forcing extensions and ground models, ordered by inclusion. Mostowski showed that any finite poset embeds into the generic multiverse while preserving the nonexistence of upper bounds. We obtain several improvements of his result, using what we call the blockchain construction to build generic objects with varying degrees of mutual genericity. The method accommodates certain infinite posets, and we can realize these embeddings (...) via a wide variety of forcing notions, while providing control over lower bounds as well. We also give a generalization to class forcing in the context of second-order set theory, and exhibit some further structure in the generic multiverse, such as the existence of exact pairs. (shrink)

Background Journal editors are responsible for what they publish and therefore have a duty to correct the record if published work is found to be unreliable. One method for such correction is retraction of an article. Anecdotal evidence suggested a lack of consistency in journal policies and practices regarding retraction. In order to develop guidelines, we reviewed retractions in Medline to discover how and why articles were retracted. Methods We retrieved all available Medline retractions from 2005 to 2008 and a (...) one-in-three random selection of those from 1988 to 2004. This yielded 312 retractions (from a total of 870). Details of the retraction including the reason for retraction were recorded by two investigators. Results Medline retractions have increased sharply since 1980 and currently represent 0.02% of included articles. Retractions were issued by authors (63%), editors (21%), journals (6%), publishers (2%) and institutions (1%). Reasons for retraction included honest error or non-replicable findings (40%), research misconduct (28%), redundant publication (17%) and unstated/unclear (5%). Some of the stated reasons might have been addressed by corrections. Conclusions Journals' retraction practices are not uniform. Some retractions fail to state the reason, and therefore fail to distinguish error from misconduct. We have used our findings to inform guidelines on retractions. (shrink)

Using a two-part instrument consisting of eight vignettes and twenty character traits, the study sampled 141 employees of a mid-west financial firm regarding their predispositions to prefer utilitarian or formalist forms of ethical reasoning. In contrast with earlier studies, we found that these respondents did not prefer utilitarian reasoning. Several other hypotheses were tested involving the relationship between people's preferences for certain types of solutions to issues and the forms of reasoning they use to arrive at those solutions; the nature (...) of the relationship between utilitarian and formalist categories ; and the possibility of measuring ethical predispositions using different methods. (shrink)

Abstnn Eye movements were monitored while subjects performed parallel and serial sarah tasks. In Experiment la, subjects searched for an “O' among "X"s (parallel condition) and for a 'T" among "L"s (serial condition). In the parallel condition of Eqcriment lb, “q)" was the target and “O"s were distractors; in the serial condition, time..

Large-scale sequencing tests, including whole-exome and whole-genome sequencing, are rapidly moving into clinical use. Sequencing is already being used clinically to identify therapeutic opportunities for cancer patients who have run out of conventional treatment options, to help diagnose children with puzzling neurodevelopmental conditions, and to clarify appropriate drug choices and dosing in individuals. To evaluate and support clinical applications of these technologies, the National Human Genome Research Institute and National Cancer Institute have funded studies on clinical and research sequencing under (...) the Clinical Sequencing Exploratory Research program as well as studies on return of results. Most of these studies use sequencing in real-world clinical settings and collect data on both the application of sequencing and the impact of receiving genomic findings on study participants. They are occurring in the context of controversy over how to obtain consent for exome and genome sequencing. (shrink)

The present study applies a new method for investigating dynamic unconscious processes. The method consists of selection of words from patient interview and test protocols that in the clinicians' judgments capture the patients' conscious symptom experience and the hypothetical unconscious conflict related to the symptom, subliminal and supraliminal presentation of these words, signal analysis of event-related potentials obtained to the word presentations. Eight phobics and three patients suffering from pathological grief reactions served as subjects. A time-frequency ERP analysis revealed that (...) subjects' ERPs classified the unconscious conflict words better subliminally than supraliminally, while the reverse was true for the conscious symptom words = 2.82, p = .011). The relationship between frequency and latency revealed a similar mirror image pattern for the unconscious conflict and conscious symptom words . This method demonstrated that objective, brain-based evidence for unconscious conflict can be obtained. (shrink)