An alternative antigen receptor, named the variable lymphocyte receptor (VLR), was first identified in lampreys in 2004. Since then, the mechanism of VLR diversification via somatic gene assembly and the function of VLR‐expressing lymphocytes have been the subject of much research. VLRs comprise leucine‐rich repeat (LRR) motifs and are found only in the most phylogenetically distant vertebrates from mammals, lampreys, and hagfish. Previous reports showed that VLRA and VLRB are reciprocally expressed by lymphocytes that resemble T‐ and B cells; however, (...) more recent reports show that another VLR, VLRC, is expressed on a third lymphocyte lineage, which may be equivalent to γδ T cells. The existence of three major lymphocyte lineages – one B‐cell‐like and two T‐cell‐like – and their development in lampreys, parallels the mammalian adaptive immune system. This suggests that these three cell lineages were present in the common vertebrate ancestor approximately 500 million years ago. (shrink)

Innovative verbs in Japanese are formed from nouns of various sources including loanwords, Sino-Japanese nouns, mimetics, and proper names. Regardless of their different origin, these innovative denominal verbs exhibit a collection of intriguing properties, ranging from phonological, morphological, to semantic and pragmatic. These properties are not strictly predictable from the component parts including the nature of the parent noun and verbal morphology. Such an unpredictable nature is suggestive of a constructional analysis. The form-meaning-function complex takes a templatic representation, which expresses (...) the phonological and morphological characteristics, and associated with it are semantic and pragmatic properties. These phonological, morphological, semantic, and pragmatic properties combine to capture the nature of innovative denominal verbs as a construction. The analysis supports the idea of applying construction grammar to morphology along the lines of the developing field of construction morphology (e.g., Booij, Compounding and derivation: Evidence for construction morphology, John Benjamins, 2005, Construction morphology and the lexicon: 34–44, Cascadilla Press, 2007, Linguistische Berichte 19: 1–14, 2009a, Compounding and construction morphology, Oxford University Press, 2009b). We further show how insights from templatic (or prosodic) morphology (e.g., McCarthy and Prince, Prosodic morphology, University of Massachusetts and Brandeis University, 1986, Natural Language and Linguistic Theory 8: 209–282, 1990) can be conceptualized in terms of construction grammar. (shrink)

Situationists (e.g., Doris in Lack of character: personality and moral behavior, Cambridge University Press, Cambridge, 2002; Harman in Proc Aristot Soc 99:315–331, 1999. 10.2307/4545312), with reference to empirical work in psychology, have called into question the predictive and explanatory power of character traits and on this basis have criticized the empirical adequacy of moral virtue. More recently, Alfano (Philos Q 62(247):223–249, 2012; Character as moral fiction, Cambridge University Press, Cambridge, 2013) has extended the situationist critique from virtue ethics to virtue (...) epistemology. On the line he advances, virtue responsibilism—the view that intellectual character traits play an important part in traditional and untraditional epistemological inquiries—is criticized as empirically inadequate in light of the extent to which individuals are shown to be susceptible to seemingly trivial and epistemically irrelevant situational influences. Alfano’s attempted redeployment of the situationist challenge to virtue responsibilism is on closer inspection not as straightforward as he claims. It is granted that the empirical adequacy of virtue responsibilism will be eventually threatened if it can be shown that virtuous motivation is, in light of situational factors, causally ineffective. As it turns out, various psychological studies which situationists have overlooked, suggest that virtuous motivation is causally efficacious in a way that favours the position of the virtue responsibilist over the situationist. In the first part of this paper, I outline the hard core of virtue theory: both a rich motivation requirement, and a commitment to the inherent relation between virtue and a good life; then I assess whether these are undermined by situationist criticism. I address the confusion of the existing debate, and the conclusion drawn is that virtue theory ultimately remains unscathed. In the second part of my paper I defend the empirical adequacy of virtue theory based on self-determination theory. When we afford closer attention to studies on the orientation of our motivation, it becomes clear how the dynamics of our motivation have a tremendous influence on desirable behavioural outcomes: a good life. (shrink)

The child objection is a major challenge for reductionism, which requires hearers to have positive reasons for testimonial justification. However, it has been pointed out that anti-reductionism, which requires only the absence of negative reasons, or defeaters, suffers from the same kind of problem. The child objection presupposes the empirical thesis that “children do not have the capacity to consider reasons,” but the plausibility of this assumption may be revealed by developmental psychology research on selective trust. This paper uses recent (...) epistemological studies as a guide to narrow down the types of defeaters that children are required to consider, and then clarifies what kind of reasons various experiments can be said to test the ability to consider, and in what sense children who pass the test can be said to be “considering” reasons. In doing so, we clarify the scope and limits of the implications that selective trust studies can have for reductionism and anti-reductionism. We then suggest what future psychological research is desired from an epistemological interest to go beyond the current limitations. (shrink)

In the previous discussions of irrationality in philosophy and psychology, the focus has been on irrationality at the level of individuals, such as irrational reasoning, irrational judgment, irrati...

This paper offers an account of collective epistemic vices, which we call the “group identification account”. The group identification account attributes collective epistemic vices to the groups that are constituted by “group identification”, which is a primitive and non-doxastic self-understanding as a group member (Turner, 1982; Brewer, 1991; Brewer & Gardner, 1996; Pacherie, 2013; Salice & Miyazono, 2020). The distinctive feature of the group identification account is that it enables us to attribute epistemic vices not just to established social groups (...) (e.g. committees, research teams, juries) but also to loose social groups (e.g. loosely connected people in an echo chamber) when they are constituted by group identification. The group identification account is contrasted with Fricker’s (2010, 2020) influential account, the “joint commitment account”, which focuses on established social groups, and has difficulty in making sense of collective epistemic vices of loose social groups. The group identification account is motivated by the fact that collective epistemic vices can be useful to diagnose not only the epistemic performance of established groups but also that of loose groups in real-life cases, such as echo chamber (Nguyen, 2020), implicit bias (Holroyd, 2020), group polarization (Broncano-Berrocal & Carter, 2021), etc. (shrink)

In his book Bad Beliefs, Neil Levy defends the engineering of our epistemic environment by removing epistemic pollutions and by nudging people through second-order evidence. Although we agree with his core ideas, in this commentary, we aim at supplementing his approach in light of the participation of the general public in science. In the first part, we argue that the issue of participatory epistemic injustice in the scientific community remains unaddressed in Levy’s discussion and that addressing the issue is equal (...) to removing an epistemic pollution. In the second part, we address the issue of transparency in nudging. Here, we discuss the significance of public engagement in controlling the system of nudges to respect our rational and autonomous choices. (shrink)

Synthetic approaches to social interaction support the development of a second-person neuroscience. Agent-based models and psychological experiments can be related in a mutually informing manner. Models have the advantage of making the nonlinear brainenvironmentbrain system as a whole accessible to analysis by dynamical systems theory. We highlight some general principles of how social interaction can partially constitute an individual's behavior.

have extremely harmful impacts on an individual’s physical, social and mental health throughout their life-span. Recently, it has been reported that maternal ACEs increase the risk of developmental delay in the offspring across generations. This mini review focuses on the direct relationship between maternal ACEs and child developmental delay, and potential mediators/moderators that associate their relationship. Six studies were identified using three search engines. The results indicated that four out of six studies reported at least one significant direct association between (...) maternal ACEs and child development. Additionally, maternal biological, psychological, and social factors were identified as mediators or moderators. In summary, we identified that maternal ACEs increased the risk of developmental delay in children via biological and psychosocial pathways. Future research should examine potential buffering factors and identify when it is crucial to break the intergenerational transmission. (shrink)

Upshot: In the model simulation and the human experiment, we observed that attention shifted from a tool to a task. This was accompanied by bodily extension. However, our experiments lack a sense of bodily incorporation (the sense of ownership. Based on the valuable commentaries, we would like to discuss the necessary conditions for possible bodily incorporation in terms of redundant degrees of freedom, synchronous visual tactile stimulation, and 1/f noise.

Context: Our body schema is not restricted to biological body boundaries (such as the skin), as can be seen in the use of a cane by a person who is visually impaired or the “rubber hands” experiment. The tool becomes a part of the body schema when the focus of our attention is shifted from the tool to the task to be performed. Problem: A body schema is formed through interactions among brain, body, tool, and environment. Nevertheless, the dynamic mechanisms (...) underlying changes in the body schema are still not fully understood. Method: To study the changing conditions of the body schema (e.g., a shift of attention), a simulation model of object discrimination was extended to differentiate between two kinds of sensitivities – sensitivity to an object being directly manipulated and sensitivity to another object being manipulated by the first. The proposed model consisted of windmills with different numbers of vanes. A model agent was required to determine the number of vanes on a windmill by touching the vanes blindly with an arm controlled by a neural network. Placing a second windmill beside the first and gearing the two windmills to move associatively resulted in the agent using the first windmill as a tool with which to discern the number of vanes on the second windmill. In other words, an agent’s body schema can shift from its arm tip to the boundary between the first and second windmills. We then introduced an experiment with a real windmill model to test the hypothesis demonstrated by the theoretical model. Results: We demonstrated that even simple computational agents can have two different sensitivities to the windmills. One agent becomes sensitive to the first windmill and insensitive to the second one. Another agent becomes insensitive to the first windmill and sensitive to the second one by using the first one as a tool. Therefore, we concluded that the boundary of the body schema was extended to the first windmill in the case of the latter agent because paying attention to the task to be performed instead of the tool itself is essential for the tool to be considered as part of the body schema. Analysis of the experiments using a computational model and human experimentation revealed that a shift from an irregular to a regular movement of a windmill is an indication of extension of the body schema. Constructivist content: Our insights are beneficial for enactive cognitive science. This is because an extended body schema questions the Cartesian separation between subject and object, and the self and the environment. (shrink)

For the most part, the papers collected in this volume stern from presentations given at a conference held in Tucson over the weekend of May 31 through June 2, 1985. We wish to record our gratitude to the participants in that conference, as well as to the National Science Foundation and the University of Arizona SBS Research Institute for their financial support. The advice we received from Susan Steele on organizational matters proved invaluable and had many felicitous consequences for the (...) success of the con­ ference. We also would like to thank the staff of the Departments of Linguistics of the University of Arizona and the University of Massachusetts at Amherst for their help, as weIl as a number of individuals, including Lin Hall, Kathy Todd, and Jiazhen Hu, Sandra Fulmer, Maria Sandoval, Natsuko Tsujimura, Stuart Davis, Mark Lewis, Robin Schafer, Shi Zhang, Olivia Oehrle-Steele, and Paul Saka. Finally, we would like to express our gratitude to Martin Scrivener, our editor, for his patience and his encouragement. Vll INTRODUCTION The term 'categorial grammar' was introduced by Bar-Rillel as a handy way of grouping together some of his own earlier work and the work of the Polish logicians and philosophers Lesniewski and Ajdukiewicz, in contrast to approaches to linguistic analysis based on phrase structure grammars. (shrink)

Open peer commentary on the article “Investigating Extended Embodiment Using a Computational Model and Human Experimentation” by Yuki Sato, Hiroyuki Iizuka & Takashi Ikegami. Upshot: First, we comment on a potential weakness highlighted by the use of self-reporting in the human-coupled windmill experiment as described in the target article. Second, we suggest that the authors treat their windmill models as soft-assembled dynamical systems. This would allow them to investigate extended body schemes by looking for 1/f noise in the interface (...) between the agent and the windmills. (shrink)

Open peer commentary on the article “Investigating Extended Embodiment Using a Computational Model and Human Experimentation” by Yuki Sato, Hiroyuki Iizuka & Takashi Ikegami. Upshot: The target article’s findings on the focus of attention in extending an agent’s body schema are consistent with those in developmental psychology and neuroscience on goal-directed action. The consequences of these findings are that embodiment can be extended in a variety of ways, not all of which require direct physical manipulation.

Open peer commentary on the article “Investigating Extended Embodiment Using a Computational Model and Human Experimentation” by Yuki Sato, Hiroyuki Iizuka & Takashi Ikegami. Upshot: Sato and colleagues make use of an innovative method that combines robotics modeling and psychological experimentation to investigate how tool use affects our living and lived embodiment. I situate their approach in a general shift from robotics to human-computer interface studies in enactive cognitive science, and speculate about the necessary conditions for the bodily incorporation (...) of tools. (shrink)