The enrolment of children and adolescents in health research requires that attention to be paid to specific assent and consent requirements such as the age range for seeking assent; conditions for parental consent (and waivers); the age group required to provide written assent; content of assent forms; if separate assent and parental consent forms should be used, consent from emancipated young adults; reconsent at the age of adulthood when a waiver of assent requirements may be appropriate and the conditions for (...) waiving assent requirements. There is however very little available information for researchers and ethics committees on how to navigate these different issues. To provide guidance to research initiatives, the SickleInAfrica consortium conducted a thematic analysis of a sample of research ethics guidelines and procedures in African countries, to identify guidance for assent requirements in health research. The thematic analysis revealed that 12 of 24 African countries specified the age group for which assent is required. The minimum age for written assent varied across the countries. Five countries, Algeria, Botswana, Cameroon, Nigeria and The Democratic Republic of Congo require consent from both parents/family council in certain circumstances. Botswana, Nigeria, South Africa and Uganda have specific assent/consent requirements for research with emancipated minors. South Africa and Algeria requires re-consent at onset of adulthood. Five countries (Botswana, Cameroon, Nigeria, South Africa and Tanzania) specified conditions for waiving assent requirements. The CIOMS and the ICH-GCP guidelines had the most comprehensive information on assent requirements compared to other international guidelines. An interactive map with assent requirements for different African countries is provided. The results show a major gap in national regulations for the inclusion of minors in health research. The SickleInAfrica experience in setting up a multi-country SCD registry in Africa highlights the need for developing and harmonising national and international guidelines on assent and consent requirements for research involving minors. Harmonisation of assent requirements will help facilitate collaborative research across countries. (shrink)

This paper discusses justice as an inherent aspect of life in traditional African societies. It further examines the degree to which constitutions of African countries recognise and promote the traditions and customary practices. It is noted that of late, in the desire to contextualise justice, human rights has to a large extent become the yardstick. This universal idea often creates conflicts with African customary practices which indeed represent the expectations of individuals or groups within such customary traditions. It is therefore (...) possible in the modern context to have customary practices that are at variance with the contents of human rights. The paper cautions that any effort therefore to transform customary practices to fall in line with the universal human rights imbued idea of justice could result in a situation where traditional societies are forced to conform to standards of justice that become impositions. (shrink)

This paper contributes to the discussion on methodological decolonisation in business ethics research by illustrating how local epistemologies can shape methodology. Historically, business ethics research has been dominated by Western methodologies, which have been argued to be restrictive and limit contextually relevant theorising in non-Western contexts. Over the past decade, scholarship has called for more diversity in research methods and epistemologies. This paper regards arguments founded along neatly divided universalist versus contextualised methodologies as a false dilemma. Instead, we explore how (...) _ubuntu_, a sub-Saharan African epistemology, can contribute as a complementary epistemology and methodology to interpretivism when conducting business ethics research in sub-Saharan Africa. The paper discusses four aspects—research agenda, access, power relations, and context-sensitive methods—that highlight practical ways in which _ubuntu_ epistemology, with its communitarian and relational underpinnings, can enhance business ethics research. We illustrate that methodological decolonisation can be achieved by fusing relevant elements of local epistemologies and methodologies and conventional methodologies to generate context-relevant research approaches. (shrink)

This book examines the labour standards provisions in a number of Regional and Bilateral Trade Agreements, and assesses the potential of using the relevant clauses in these trade agreements as a benchmark for a multilateral approach. Based on the lessons learned from the Regional model, the book proposes a Global Labour and Trade Framework Agreement (GLTFA) combined with a joint ILO/WTO enforcement mechanism to resolve the contentious issue of the link between the CLS and international trade. The history of the (...) linkage between the Core Labour Standards (CLS) and international trade dates back roughly 150 years, and has recently become one of the most vexing issues facing policy-makers. At the heart of the debate is the question whether or not trade sanctions should be imposed on countries that do not respect the CLS as embodied in multilateral conventions administered by the International Labour Organization (ILO). Concretely, this would entail inserting a social clause in the World Trade Organization (WTO) rules, and would trigger the imposition of sanctions on those countries that do not adhere to the CLS. Kofi Addo is a policy advisor to the Board of Governors of the International Baccalaureate Organisation. He holds a PhD in law from the University of Bern, Switzerland.. (shrink)

Informed consent is considered by many to be a moral imperative in medical research. However, it is increasingly acknowledged that in many actual instances of consent to participation in medical research, participants do not employ the provided information in their decision to consent, but rather consent based on the trust they hold in the researcher or research enterprise. In this article we explore whether trust-based consent is morally inferior to information-based consent. We analyse the moral values essential to valid consent (...) – autonomy, voluntariness, non-manipulation, and non-exploitation – and assess whether these values are less protected and promoted by consent based on trust than they are by consent based on information. We find that this is not the case, and thus conclude that trust-based consent if not morally inferior to information-based consent. (shrink)

Prepublication peer review should be abolished. We consider the effects that such a change will have on the social structure of science, paying particular attention to the changed incentive structure and the likely effects on the behaviour of individual scientists. We evaluate these changes from the perspective of epistemic consequentialism. We find that where the effects of abolishing prepublication peer review can be evaluated with a reasonable level of confidence based on presently available evidence, they are either positive or neutral. (...) We conclude that on present evidence abolishing peer review weakly dominates the status quo. (shrink)

Background There are several psychosocial and ethical issues surrounding the decision to be a living kidney donor. The present study aimed to determine the perceptions of psychosocial and ethical issues that living kidney donors may have, and analyze their psychological characteristics.Methods Face-to-face semi-structured interviews were conducted with 15 donors. Thematic analysis was then performed to categorize the thematic elements of the transcripts. All procedures were approved by the relevant review board.Results Four main categories were identified: Awareness of family dynamics, barriers (...) to a proper understanding, contrasting psychological effects of recipient presence in clinical practice, insufficient information explained in informed consent.Conclusion Donors felt that they took on the “role as a care giver” for the recipient and were less aware of themselves as patients. This is a new concept that has not been shown in previous studies. Donors exist within the recipient and family, and the range of their autonomy may go beyond the traditional concept of autonomy and be rooted in relational autonomy. This study suggested that medical treatment in the presence of the recipient promotes the relational autonomy of the donor. (shrink)

Critical race theorists and standpoint epistemologists argue that agents who are members of dominant social groups are often in a state of ignorance about the extent of their social dominance, where this ignorance is explained by these agents' membership in a socially dominant group (e.g., Mills 2007). To illustrate this claim bluntly, it is argued: 1) that many white men do not know the extent of their social dominance, 2) that they remain ignorant as to the extent of their dominant (...) social position even where this information is freely attainable, and 3) that this ignorance is due in part to the fact that they are white men. We argue that on Buchak's (2010, 2013) model of risk averse instrumental rationality, ignorance of one's privileges can be rational. This argument yields a new account of elite-group ignorance, why it may occur, and how it might be alleviated. (shrink)

Given the importance of scientific research in shaping our perception of the world, and our senses of what policies will and won’t succeed in altering that world, it is of great practical, political, and moral importance that we carry out scientific research with integrity. The phenomenon of scientific fraud stands in the way of that, as scientists may knowingly enter claims they take to be false into the scientific literature, often knowingly doing so in defiance of norms they profess allegiance (...) to. In this chapter we take a look at some of the causes of scientific fraud, and how it might be manifested in large-scale research teams and situations of anonymous authorship. We find that such cases make trouble for what might seem like intuitive answers to the question “who should be held responsible for this fraud?”, and we argue that in such cases it would be better to hold the entire community responsible for seeing to it that there is less fraud. (shrink)

On balance, Africa generally has made some progress in good governance under liberal, multiparty democracy in the past two or three decades. But there are well‐noted, wide‐ranging dysfunctions in governance, which inhibit human development and fulfilment. Several papers have been published, which propose various solutions to the dysfunctions. Among them are proposals for types of all‐inclusive democratic politics. I examine a couple of these proposals and conclude that they generate formidable feasibility challenges, even for the types of democracy they advocate. (...) This paper focuses on Ghana, but with a thrust intended to have import for the sustainability of democracy across Africa. The argument is basically that the operating democratic constitutions in Africa provide a normatively desirable liberal, multiparty democracy, which promises a reasonably good life for all without exception; but practice has resulted in enduring, multiple deprivations and low standards of living for millions of citizens. The reason for the undesirably wide gap between the ideal and the practice is not because multiparty democracy is inconsistent with African traditions or is otherwise not good for Africans, as some scholars claim, but because of those who tend to run it—their general incompetence, including or marked by their intellectual and ethical inability to rise above partisan limitations and failure to leverage the efficiencies of the free market system. The proposed solution for Ghana, intended to eliminate or significantly mitigate the dysfunctions just mentioned and to sustain the multiparty democracy, is to redesign the National Development Planning Commission (NPDC), a constitutional organ which serves the partisan executive, into a robust, non‐partisan, independent institution, anchored on the principles of separation of powers and checks and balances, to enable it to do at least the following two things: (a) to produce, with representation from key stakeholders, including political parties, technocratically objective, competent, efficient and accountable rolling and all‐inclusive National Development Plans (NDPs) in place of vote‐inspired and partisan manifestoes, with budgets approved by parliament; and (b) to monitor, evaluate and report on the governing party's implementation of the NDPs to parliament. Democracy will become sustainable as the general quality of lives grows steadily under the continuous implementation of all‐inclusive NDPs, which are to be crafted to efficiently and sustainably deliver public goods and services that serve district, regional and the common needs and interests of all Ghanaians rather than the interests of the few and powerful or, at best, of majorities. (shrink)

This paper investigates a distributed coordination control for a class of high-order uncertain multiagent systems. Under the framework of iterative learning control, a novel fully distributed learning protocol is devised for the coordination problem of MASs including time-varying parameter uncertainties as well as actuator saturations. Meanwhile, the learning updating laws of various parameters are proposed. Utilizing Lyapunov theory and combining with Graph theory, the proposed algorithm can make each follower track a leader completely over a limited time interval even though (...) each follower is without knowing the dynamics of the leader. Moreover, the extension to formation control is made. The validity and feasibility of the algorithm are verified conclusively by two examples. (shrink)

Social scientists use many different methods, and there are often substantial disagreements about which method is appropriate for a given research question. In response to this uncertainty about the relative merits of different methods, W. E. B. Du Bois advocated for and applied “methodological triangulation”. This is to use multiple methods simultaneously in the belief that, where one is uncertain about the reliability of any given method, if multiple methods yield the same answer that answer is confirmed more strongly than (...) it could have been by any single method. Against this, methodological purists believe that one should choose a single appropriate method and stick with it. Using tools from voting theory, we show Du Boisian methodological triangulation to be more likely to yield the correct answer than purism, assuming the scientist is subject to some degree of diffidence about the relative merits of the various methods. This holds even when in fact only one of the methods is appropriate for the given research question. (shrink)

We argue that the main results of scientific papers may appropriately be published even if they are false, unjustified, and not believed to be true or justified by their author. To defend this claim we draw upon the literature studying the norms of assertion, and consider how they would apply if one attempted to hold claims made in scientific papers to their strictures, as assertions and discovery claims in scientific papers seem naturally analogous. We first use a case study of (...) William H. Bragg’s early 20th century work in physics to demonstrate that successful science has in fact violated these norms. We then argue that features of the social epistemic arrangement of science which are necessary for its long run success require that we do not hold claims of scientific results to their standards. We end by making a suggestion about the norms that it would be appropriate to hold scientific claims to, along with an explanation of why the social epistemology of science—considered as an instance of collective inquiry—would require such apparently lax norms for claims to be put forward. (shrink)

How diverse is philosophy? In this paper we explore recent data on the racial, ethnic, and gender diversity of philosophy students and faculty in the United States. We have found that women are underrepresented in philosophy at all levels from first-year intention to major through senior faculty. The past four years have seen an increase in the percentage of women philosophy majors at the undergraduate level, but it remains to be seen if this recent increase in the percentage of women (...) will eventually also show at more advanced stages. Temporal trends since 2000 also show substantial increases in the racial and ethnic diversity of philosophy majors at all levels of education from first-year undergraduate through PhD, with substantial declines in the percentage of non-Hispanic White philosophy majors and substantial increases in all other commonly measured racial/ethnic groups except for Native American / Alaska Native. Despite generally increasing diversity, people who identify as Hispanic (any race), or non-Hispanic Native American, Alaska Native, or Black remain substantially underrepresented in philosophy at all levels compared to their presence in the U.S. population, and in some cases also as compared to other majors. (shrink)

Background: Individual, comprehensive, and written informed consent is broadly considered an ethical obligation in research involving the sampling of human material. In developing countries, however, local conditions, such as widespread illiteracy, low levels of education, and hierarchical social structures, complicate compliance with these standards. As a result, researchers may modify the consent process to secure participation. To evaluate the ethical status of such modified consent strategies it is necessary to assess the extent to which local practices accord with the values (...) underlying informed consent. Methods: Over a 2-week period in April 2014 we conducted semistructured interviews with researchers from a genetic research institute in rural Pakistan and families who had given blood samples for their research. Interviews with researchers focused on the institute’s requirements for consent, and the researchers’ strategies for and experiences with obtaining consent in the field. Interviews with donors focused on their motivation for donating samples, their experience of consent and donation, and what factors were central in their decisions to give consent. Results: Researchers often reported modifications to consent procedures suited to the local context, standardly employing oral and elder consent, and tailoring information to the social education level of donor families. Central themes in donors’ accounts of their decision to consent were the hope of getting something out of their participation and their remarkably high levels of trust in the researchers. Several donor accounts indicated a degree of confusion about participation and diagnosis, resulting in misconceived expectations of therapeutic benefits. Conclusions: We argue that while building and maintaining trusting relationships in research is important—not least in developing countries—strategies that serve this endeavor should be supplemented with efforts to ensure proper provision and understanding of relevant information, specifically about the nature of research and measures for individual consent and opt-out. (shrink)

Scientific advances in health care have been disproportionately distributed across social strata. Disease burden is also disproportionately distributed, with marginalized groups having the highest risk of poor health outcomes. Social determinants are thought to influence health care delivery and the management of chronic diseases among marginalized groups, but the current conceptualization of social determinants lacks a critical focus on the experiences of people within their environment. The purpose of this article was to integrate the literature on marginalization and situate the (...) concept in the framework of social determinants of health. We demonstrate that social position links marginalization and social determinants of health. This perspective provides a critical lens to assess the societal power dynamics that influence the construction of the socio‐environmental factors affecting health. Linking marginalization with social determinants of health can improve our understanding of the inequities in health care delivery and the disparities in chronic disease burden among vulnerable groups. (shrink)

I analyse the political, economic, and cultural circumstances that have given rise to persistent political disputes about race (known colloquially as “the culture war”) among a subset of Americans. I argue that they point to a deep tension between widely held normative aspirations and pervasive and readily observable material facts about our society. The characterological pathologies this gives rise to are discussed, and a normatively preferable path forward for an individual attempting to reconcile themselves to the current social order is (...) suggested. (shrink)

This paper looks at the metaphorical and metonymic expressions derived fromnsa, ‘hand’. I will analyse and discuss hand metaphoric and metonymic expressions in relation with the universal concept of the agility and versatility of the hand as an important aspect of the human being. The paper projects the concept of the hand in the Akan cultural system and looks at how it has expanded into compound words, idioms and proverbs. We will look at the cognitive, semantics, sociolinguistics and pragmatics ofnsa, (...) ‘hand’. The paper is discussed under the theory of conceptual metaphor as expounded by Lakoff and Johnson and followed by many scholars in the western world, Asia and Africa. (shrink)

This study examined the factors driving the public value of e-government from the viewpoint of the Chinese people. The usage of ICT through e-government systems must generate the adequate corresponding public value that can motivate the acceptance of e-government services. The sample 517 data generated from Chinese citizens were analyzed using AMOS 23 software by undertaking the structural equation model system of analysis. The results show that constructs such as information quality, service parameters, user orientation, efficiency, openness, and responsiveness were (...) significantly related to the public value of e-government. Additionally, the research validated that the public value of e-government has a direct influence on the behavioral intention to adopt e-government services. The managerial and practical implications of these research findings on the public value of e-government and the acceptance of e-government services are dissected meticulously. (shrink)

This chapter is a response to the decades of Western skepticism and cynicism regarding the sustainability of democracy in Africa toward the end of the last century as most African countries experienced what political scientists term the third wave of democratization. Focusing on the human rights tradition in Africa, which is given as the main reason for the skepticism, this chapter argues to the contrary that not only is there a vibrant tradition of human rights in Africa with particular reference (...) to the Akan model, but that its existence offers one of the best explanations for the relative success of democracy in Africa from the last century to the recent. The chapter shows further that an objective analysis into the Akan culture will reveal that the Akan conception of human rights which compliments negative rights with positive rights in principle and practice is more relevant and heuristic within African contexts than dominant conceptions of human rights from the Global North. This is seen in its demonstrated potential for facilitating and sustaining African democracies to maturity, despite the pressures from the pandemic and global economic crises. (shrink)

Responses to the COVID-19 pandemic prompted people and institutions to turn to online virtual environments for a wide variety of social gatherings. In this perspectives article, we draw upon our previous work and interviews with Ghanaian Christian leaders to consider implications of this shift. Specifically, we propose that the shift from physical to virtual interactions mimics and amplifies the neoliberal individualist experience of abstraction from place associated with Eurocentric modernity. On the positive side, the shift from physical to virtual environments (...) liberates people to selectively pursue the most fulfilling interactions, free from constraints of physical distance. On the negative side, the move from physical to virtual space necessitates a shift from material care and tangible engagement with the local community to the psychologization of care and pursuit of emotional intimacy in relations of one’s choosing—a dynamic that further marginalizes people who are already on the margins. The disruptions of the pandemic provide an opportunity to re-set social relations, to design ways of being that better promote sustainable collective well-being rather than fleeting personal fulfillment. (shrink)

The existence of philosophy as an academic discipline in African universities has been jeopardized by a growing skepticism regarding the value of contemporary African philosophy. First, it is argued that the discipline is either a Western ideology or an instrument of that ideology for the entrenchment of Western imperialism in Africa. Further, it is argued that as a discipline philosophy is too removed from reality to be of any relevance towards development. In short, the discipline should be rejected from African (...) universities for being either counterproductive or nonproductive to the process of development. ;It is the conclusion of this dissertation that both skeptical arguments lack plausibility, and that contemporary African philosophy is neither an ideology, an instrument of any ideology, nor a luxury even for the poorest countries of Africa. The first argument is refuted by arguing that the characteristics of philosophy, such as its critical epistemological attitude, rigorous methodology, and open-ended conclusions, as well as its logical status as a second-order activity that reflects critically on all disciplines including itself, are too incompatible with the corresponding characteristics of the pejorative Marxist sense of ideology presupposed by the critics. ;The second argument is refuted by arguing that contemporary African philosophy, like its Western counterpart, cultivates critical thinking skills, creativity, problem-solving skills, and certain liberal attitudes, all of which promote morality, the democratic way of life, and scientific thinking. In support of this argument a formal representation of the dilemma of development, a new theory of development, and a new ideology for developing countries are projected and defended against their relevant alternatives as the best means for dissolving the dilemma and for achieving accelerated successful development in Africa. ;My counter-arguments are supported by showing how contemporary African philosophers are facilitating the process of development through their analyses and prescriptions for transcending cultural barriers to a general orientation to science. (shrink)

Abstract ‘PLATO’S THEORY OF CHANGE: A POPPERIAN RECONSTRUCTION AND ITS SIGNIFICANCE FOR TRADITIONAL AND EMERGING DEMOCRACIES,’ The International Journal of Applied Philosophy, Vol 8 Winter/Spring 1994, No.2. -/- This paper argues that in the midst of the unprecedented actual and potential socio-political and economic changes and transformations in our world toward the end of the 20th Century, the need for some philosophical grounding and guidance has become an imperative if only to avoid a global disaster or change for its own (...) sake. The changes cited include the collapse of the Soviet hegemony and the emergence of pro-democracy movements throughout in Eastern Europe, Latin America, South East Asia, and Africa including the post-Apartheid South Africa. Other changes mentioned include the integration of EEC members into a political unit, the threats from international terrorism, the increasing socio-economic gap and anti-Black racism in the US, and the changes promised by the new US President, Bill Clinton. The paper initiates discussion about the prospect for such a philosophical grounding and guidance by focusing on Plato’s Theory of Change and the possibility of utilizing it as a fulcrum for the ongoing global changes. Following Karl Popper’s lead, (in The Open Society and Its Enemies Vol .I, The Spell of Plato) Plato’s Theory is critiqued on account of its inherent historicism, totalitarianism, and social injustice. Unlike Popper who stops at the criticism however, this paper proceeds with a reconstruction of Plato’s Theory of Change in the light of the criticism as well as the criticism of Popper’s own inaccurate representation of Plato’s Theory. The new theory of change, aptly called, The Plato-Popper Theory of Change is applied to analyzing and theoretically solving or minimizing some of the problems within traditional democracies like the US and Emerging democracies in the Third World. Finally, the paper also presents a challenge to professional philosophers, especially those skilled in ethics and socio-political philosophy, to shift their focus from solving the abstract problems in some possible worlds to solving the real problems of this world in which we live and die. [312 words] . (shrink)

In response to the rapid and global socio-economic and political transformations within traditional and emerging democracies toward the end of the 20th Century and the beginning of the 21st Century, the need for a credible philosophical theory providing some explanatory wisdom and guidance to avoid descent into chaos, this paper argues, has become an imperative. This paper examines the plausibility of utilizing Plato's Theory of Change for the purpose, and identifies with Karl Popper's criticism of the theory for its inherent (...) historicism and totalitarianism. However, unlike Popper who stops at the criticism of the theory, I proceed with a reconstruction of Plato's theory, partly based on Popper's criticism, and apply it to the ongoing global changes and transformations. The new Plato-Popperian Theory of Change is then tested and applied to traditional as well as emerging democracies. Finally, the paper ends with compelling recommendations for policy-makers as well as social and political philosophers. (shrink)

The limbus is a narrow band of tissue that encircles the cornea, the transparent ‘window’ into the eye. The outermost layer of the cornea is the epithelium, which is necessary for clear vision. The limbus acts as a ‘reservoir’ for limbal stem cells which maintain and regenerate the corneal epithelium. It also functions as a barrier to the conjunctiva and its blood vessels. Limbal stem cell deficiency is a general term for diseases which are characterised by the impairment of the (...) limbus, limbal stem cells and their ability to replenish the corneal epithelium through proliferation and differentiation. Consequently, sufferers experience chronic pain and progressive blindness. This paper will highlight the salient milestones of limbal stem cell biology and potential future treatments for limbal stem cell deficiency. (shrink)

Among the fields of music study, ethnomusicology has wrestled most self-consciously with matters of representation. Since its inception in the late nineteenth century as vergleischende Musikwissenschaft [comparative musicology] and throughout its turbulent history, ethnomusicology has been centrally and vitally concerned with at least three basic issues and their numerous ramifications. First is the problem of locating disciplinary boundaries: is ethnomusicology a subfield of musicology, does it belong under anthropology or ethnology, or is it an autonomous discipline?1 Second is the problem (...) of translation: what factors influence the attempt to translate the reality of other musical cultures into audio and visual recordings, verbal accounts, and transcriptions in musical notation? Is there a viable “theory of translatability”?2 Third is a network of political and ideological matters: what sorts of ethical issues constrain the practical effort to understand another culture? What is the relation between empire and ethnomusicological representation? Can we—that is, is it a good thing to—study any music without taking note of the social, economic, political, and technological circumstances of its producers? 1. A concise introduction to the field of ethnomusicology, its history, personalities, and method may be found in Barbara Krader, “Ethnomusicology,” in The New Grove Dictionary of Music and Musicians, ed. Stanley Sadie, 20 vols. , 6:275-82. The most comprehensive recent discussion of key issues in ethnomusicological research is Bruno Nettl, The Study of Ethnomusicology: Twenty-nine Issues and Concepts .2. See Johannes Fabian, Time and the Other: How Anthropology Makes Its Object , p. 43. Kofi Agawu teaches at Cornell University and is the author of Playing with Signs: A Semiotic Interpretation of Classic Music. (shrink)