In this article, we examine how the U.N. Convention on the Rights of the Child can be useful in pediatric bioethics. Adopted in 1989, the CRC reflects norms that have been deliberated upon for a long period of time and endorsed by most nations. The United States is now the only country that has not ratified the CRC.1 International human rights law shares many key moral concepts with clinical pediatric bioethics, and the CRC provides a considered language common to many (...) jurisdictions that can assist bioethicists in their daily practice and help health-care organizations in their policy development and international interactions. There may, however, be practical challenges with using the CRC in the practice of.. (shrink)

The focus of this paper is one of James Prescott Joule’s scientific contributions: the laws of heat production by electric currents in conductors. In 1841, the 22 years old Joule published a paper with the title “On the heat evolved by metallic conductors of electricity, and in the cells of a battery during electrolysis” where he presented an experimental study of that phenomenon and proposed two laws that were allegedly supported by his trials. On closer inspection, both his laboratory work (...) and his inferences can be challenged. The emphasis of this article is an attempt to understand Joule’s experimental undertaking, its highpoints and shortcomings, by a detailed analysis of this specific episode and by studying the precedents of his work and subsequent advancements. It is possible to point out several serious deficiencies of that investigation, and Joule’s contemporaries, such as Edmond Becquerel and Heinrich Lenz, did criticize some of his flaws and undertook new experiments to provide a sound basis for those laws. Besides providing a historical examination of that specific episode, this article uses this case study to tackle some features of the nature of science that may contribute to scientific education. (shrink)

The project review as outlined in this article explores the questions: What is transformative research and what is transformation as far as the community stakeholders are concerned? To what extent has the transformative research achieved its intended outcomes? The Bokamoso project is an integrated development project designed to create employment and to enable the community to learn while they make a living through a diverse range of farming activities. The participatory research as discussed here is part of the University of (...) South Africa’s research and community engagement programme, and is set in a remote, arid zone. This research coupled with community engagement aims to transform lives and create opportunities by enhancing their participation in education, training and employment creation. The project supports indigenous ways of being, knowing and doing and has succeeded in enabling the farmers trained through Bokamoso to be less dependent on social benefits. (shrink)

Working memory--the ability to keep important information in mind while comprehending, thinking, and acting--varies considerably from person to person and changes dramatically during each person's life. Understanding such individual and developmental differences is crucial because working memory is a major contributor to general intellectual functioning. This volume offers a state-of-the-art, integrative, and comprehensive approach to understanding variation in working memory by presenting explicit, detailed comparisons of the leading theories. It incorporates views from the different research groups that operate on each (...) side of the Atlantic, and covers working-memory research on a wide variety of populations, including healthy adults, children with and without learning difficulties, older adults, and adults and children with neurological disorders. A particular strength of this volume is that each research group explicitly addresses the same set of theoretical questions, from the perspective of both their own theoretical and experimental work and from the perspective of relevant alternative approaches. Through these questions, each research group considers their overarching theory of working memory, specifies the critical sources of working memory variation according to their theory, reflects on the compatibility of their approach with other approaches, and assesses their contribution to general working memory theory. This shared focus across chapters unifies the volume and highlights the similarities and differences among the various theories. Each chapter includes both a summary of research positions and a detailed discussion of each position. Variation in Working Memory achieves coherence across its chapters, while presenting the entire range of current theoretical and experimental approaches to variation in working memory. (shrink)

This paper proposes a biosemiotic conception of theories, as non-intentional organic theories, which is based on an analysis and comparison of philosopher Norwood Russell Hanson’s account of theories and zoologist Jakob von Uexküll’s theory of organisms. It is argued that Hanson’s proposals about scientific theories and their relation to observation are semiotic in nature and that there exists a correspondence between Hanson’s depiction of the relationship between theories, observation, and reality and von Uexküll’s views on the relationship between organisms and (...) their environments. This correspondence supports an account of theories that depicts them as organic extensions of our perceptual physiology. Among the epistemological consequences of this account are the following: The kind of correspondence that is established through theories between a subject and reality is related rather to a subject’s actions than to a faithful representation of every aspect of the world, it suggests a strong emphasis on the creative aspects of knowledge acquisition, and it urges a reassessment of the evolutionary epistemology of theories. (shrink)

Вследствие общности и широты своих законов физика всегда оказывала определяющее воздействие на развитие всех естественных наук, включая их теоретические основы, методологию.

We study the global properties of [Formula: see text], the Turing degrees of the n-r.e. sets. In Theorem 1.5, we show that the first order of [Formula: see text] is not decidable. In Theorem 1.6, we show that for any two n and m with n < m, [Formula: see text] is not a Σ1-substructure of [Formula: see text].

Stiff Person Syndrome is a rare autoimmune disorder associated with antibodies against glutamic acid decarboxylase, the key enzyme in γ -aminobutyric acid synthesis. In order to investigate the role of cerebral benzodiazepinereceptor binding in SPS, we performed [ 11 C]flumazenil positron emission tomography in a female patient with SPS compared to nine healthy controls. FMZ is a radioligand to the postsynaptic central benzodiazepine receptor which is co-localized with the GABA-A receptor. In the SPS patient, we found a global reduction of (...) cortical FMZ binding. In addition, distinct local clusters of reduced radiotracer binding were observed. These data provide first in vivo evidence for a reduced postsynaptic GABA-A receptor availability which may reflect the loss of GABAergic neuronal inhibition in SPS. (shrink)

This paper proposes an ethical framework for rationing publicly financed health care. We begin by classifying alternative rationing criteria according to their ethical basis. We then examine the ethical arguments for four rationing criteria. These alternatives include rationing high technology services, non-basic services, services to patients who receive the least medical benefit, and services that are not equally available to all. We submit that a just health care system will not limit basic health care to persons unable to pay for (...) it. Furthermore, justice in health care requires limiting publicly-financed non-basic health care, striving for equality in access to basic health care, and relying on medical benefit to ration non-basic health care. (shrink)

Originally published in 1963, this classic book is a rethinking of the history of Western political philosophy. Charles N. R. McCoy contrasts classical-medieval principles against the "hypotheses" at the root of modern liberalism and modern conservativism. In Part I, "The Classical Christian Tradition from Plato to Aquinas," the author lays the foundation for a philosophical "structure" capable of producing "constitutional liberty." Part II, "The Modern Theory of Politics from Machiavelli to Marx," attempts to show, beginning with Machiavelli, the reversal and (...) destruction of the pre-modern "structure" postulated in Part I. McCoy stresses the great contributions of Aristotle to political thought found in his more familiar Ethics and Politics, but also includes key insights drawn from Metaphysics and Physics. These contributions are developed and perfected, McCoy argues, by Augustine and Aquinas. Two other important features include McCoy's epistemological insights into Plato's work that will be new to many readers and the author's juxtaposition of traditional natural law with "the modernized theory of natural law." The modern account of autonomous natural law, in McCoy's view, helps explain the totalitarian direction of key aspects of modern political thought. This classic volume on the origins of modern philosophical thought remains a standard in the field. (shrink)

A detailed and profound discussion of the metaphysics of nature and morality as interpreted by Spinoza's philosophy. Especially interesting are the treatments of nature's status as created and as emanated, which are intended to save Spinoza from traditional criticisms. Although Hallett sometimes allows his defense of Spinoza to take precedence over his direct treatment of nature and morality, he clearly thinks Spinoza is generally right. Distinguished by its sober and courageous attack on unpopular issues.--R. C. N.

A project of the Gandhi Centennial Committee of Southern Illinois University, the book outlines the basic tenets of Gandhian philosophy as interpreted by Western thinkers, deals with problems of American education, and offers some reflec­tions on what kinds of solutions may be posed by educators, primarily at the university level. The Foreword and Epilogue are by two distinguished Indian educators, _K. L. Shrimali_, Vice-chancellor, and _N. A. Nikam_, former Vice-chancellor, University of Mysore.

Abstract Three recent books on public opinion attempt to map changes in the public's policy preferences over the last few decades. Such changes have clearly occurred, but a single, overriding ?public mood? remains elusive. Rather, different components of the public mood seem to move in different directions. Furthermore, it is unclear how much of the apparent change in public mood is real and how much is an artifact resulting from changes in public policies. Yet elite perceptions, or misperceptions, of public (...) opinion are important determinants of those very policies, raising questions about the coherence of opinion?led government. (shrink)

In this article, we draw upon the philosophy of critical realism to reflect upon issues concerning discovery processes and opportunity development. First, paradoxes in the relationship between opportunity discovery and creativity are identified and explained. Second, the question of how to investigate opportunities is discussed and a solution informed by critical realism presented whereby three new types of discovery are identified and defined for empirical investigation. Using critical realism to augment entrepreneurial opportunity theory, we propose that discovery processes have significance (...) beyond discovery theory and can be considered revealing for theories of opportunity development more generally. We conclude with conceptual and practical comment on the importance of ontological theorising for entrepreneurship. (shrink)

Os tempos contemporâneos evidenciamu ma a s s i n c r o n i a e n t r e a s c u l t u r a spart i cul ares e a nova const i t ui ção deestado global que se instaurou com as oci edade do conheci ment o. Quant omai or a e xpans ão de pos s i bi l i dade stécnico-científicas, menor a influênciaque as concepções morais dos gruposparticulares desempenham no (...) cenáriog l o b a l . To da s a s i nt ui ç õ e s na t ur a i sdo homo f aber são afetadas pel o fazertecnológico que responde muito maisrápida e satisfatoriamente aos anseiose necessi dades dos i ndi ví duos, t ant obi ol ógi c a quant o s oc i al ment e. Des t emodo, a atenção ao fator tecnol ógi coparece suplantar mandamentos moraisque desde outros tempos guiavam a açãoe a convivência social das pessoasContemporary ages showed an asynchronybe t we e n par t i c ul ar c ul t ur e s and t henew constitution of the global state thathas t aken pl ace wi t hi n t he soci et y ofknowledge. The more is the expansion oftechnical and scientific possibilities theless is the influence that moral conceptionsof particular groups play in the globalscene. All natural intuitions of homo faberare affected by technological making thatanswers most rapidly and satisfactorily tothe desires and needs of individuals, bothbiologically and sociologically. Thus, theattention to the technological feature seemsto supplant the moral commandments thatsince ancient times oriented the action andthe social life of persons. (shrink)