In this paper, we propose a framework for searching information through both the WWW and a human group. Though information retrieval using a searc engine in the WWW is very useful, we can not acquire local information owned by persons and not explicitly described in text. A user knows neither where target information is in the WWW nor who knows in a human group. Thus we integrate the information retrieval in the WWW with that in a human group, develop a (...) heterogeneous information search system HERIS as a multi-agent system. We develop this framework as multi-agent system consisting of user agents and search engine agents, and use contract net protocol to communication among the agents. A user agent and a search engine agent are assigned to a user and a search engine. Each of the agents maintains a user profile and a search engine profile. When a user gives a query to a system, it selectively searches information resources consisting the WWW and user group. Finally a user acquires integrated results of a hit list from the WWW and a audio/video connection to a user who can answer the query. It was found through experimental evaluation that information retrieval using a human group as an information resource is valid and a search with HERIS has a different character from conventional search engines. (shrink)

Platforms for sharing genomic and phenotype data have been developed to promote genomic research, while maximizing the utility of existing datasets and minimizing the burden on participants. The value of genomic analysis of trios or family members has increased, especially in rare diseases and cancers. This article aims to argue the necessity of protection when sharing data from both patients and family members. Sharing patients’ and family members’ data collectively raises an ethical tension between the value of datasets and the (...) rights of participants, and increases the risk of re-identification. However, current data-sharing policies have no specific safeguards or provisions for familial data sharing. A quantitative survey conducted on 10,881 general adults in Japan indicated that they expected stronger protection mechanisms when their family members’ clinical and/or genomic data were shared together, as compared to when only their data were shared. A framework that respects decision-making and the right of withdrawal of participants, including family members, along with ensuring usefulness and security of data is needed. To enable this, we propose recommendations on ancillary safeguards for familial data sharing according to the stakeholders, namely, initial researchers, genomic researchers, data submitters, database operators, institutional review boards, and the public and participants. Families have played significant roles in genetic research, and its value is re-illuminated in the era of genomic medicine. It is important to make progress in data sharing while simultaneously protecting the privacy and interests of patients and families, and return its benefits to them. (shrink)

This paper has three tasks. First, I offer an interpretation of Jeremy Bentham’s theory of language which I hope can conciliate or integrate the three rival interpretations of its epistemological implication: reductionist realist, pragmatist, and fictionalist. It is accompanied by an interpretation of Bentham’s strategy for improving the state of language, which characterizes it as a “two-level” strategy. Second, by focusing on the linguistic thoughts of three philosophers, Locke, Condillac, and Tooke, I inquire into the sources of Bentham’s theory of (...) language, and then try to evaluate the originality of Bentham’s theory in the context of the empiricist tradition of linguistic thought of the age of the Enlightenment. The inquiry also enables us to understand how Bentham’s theory came to have such a complex structure as is revealed in the first part of this paper. Third, I ask the question as to why Bentham, after about a thirty-year hiatus, suddenly resumed writing on the problems of language and logic around 1811. Through exhibiting the outline of my answer to this question, I argue that his discovery of “delusion” led him to fight the “war of words” in various fields of society, and his awareness of the strong force of delusion for aggravating the state of language made him realize the urgent necessity to develop at length “an entirely new system of Logic, in which shall be comprehended a theory of language, considered in the most general point of view.”. (shrink)

In their comprehensive review article, De Bie et al., using some references, discreetly point out that pregnant women’s decision in Domain III to undergo fetal extraction via C-section should conti...

Nanometre-sized ! '-martensites , a few nanometres in cross-sectional diameter, formed at intersections of deformation twins, have been found in a heavily deformed 316-type austenitic stainless steel and examined by high-resolution transmission electron microscopy . An orientation relationship was found to be close to the Kurdjumov-Sachs relationship, that is , . HRTEM observations were conducted with a beam direction parallel to . The observed nanometre-sized ! '-martensites exhibited a habit plane and the cross-section of the nanometre-sized ! '-martensites were elongated (...) along [545] % . It has been revealed that the nanometre-sized ! '-martensites of a few nanometres diameter formed at the intersections of deformation twins have a typical habit plane of , which is identical with that reported for a fully grown plate such as ! '-martensite. The origin of the observed habit plane is discussed on the basis of the d 112 ¢ {111} ! shear displacements assisting the % M ! ' transformation. (shrink)

Improving public understanding and acceptance are critical for promoting coronavirus vaccination. However, how to promote COVID-19 vaccine programs remains controversial due to various ethical issues. This study, thus, aimed to survey the acceptance of COVID-19 vaccines among Japanese citizens and discuss relevant ethical issues. A cross-sectional survey was conducted via an online platform. An anonymous, quantitative, self-administered online questionnaire was sent to 6965 registered Japanese residents, which included questions regarding the respondent’s general knowledge, experience, and opinions of vaccines, vaccine development, (...) COVID-19, and COVID-19 vaccines. Of the 1569 respondents, 730 and 839 were categorized into the younger and older groups, respectively. Most of the respondents possessed general knowledge of COVID-19 vaccines and their features. Of the respondents, 57.8% definitely agreed or somewhat agreed to receive COVID-19 vaccines. The older group showed significantly greater willingness to receive vaccines and higher literacy regarding vaccines in general. Possible reasons for the older group’s greater willingness to receive COVID-19 vaccines are a high risk of severe COVID-19 infection and their past accumulated experience of receiving various vaccinations. Although active public intervention could increase vaccination rates, most of the respondents did not agree with mandatory vaccination. Furthermore, a gap between the participants in the COVID-19 vaccine trials and the prioritized population in real-world vaccination should be adjusted in future vaccine development. (shrink)

BackgroundSocial cognitive impairments adversely affect social functioning in patients with schizophrenia. Although pharmacological interventions have been suggested to provide some benefits on social cognition, little information is available on the comparative efficacy of pharmacotherapy. Thus, the aim of this planned systematic review and network meta-analysis is to perform a quantitative comparison of the effects of various psychotropic drugs, including supplements, on social cognition disturbances of schizophrenia.MethodsThe literature search will be carried out using the PubMed, Embase, Cochrane Central Register of Controlled (...) Trials, PsycINFO, ClinicalTrials.gov, and International Clinical Trials Registry Platform databases from inception onward. Randomized controlled trials that examined the efficacy of drugs in social cognitive disturbances will be included, based on the most recent studies and the broader literature than previously searched. This protocol defines a priori the methods that will be used for study selection, data collection, quality assessment, and statistical syntheses.DiscussionThe findings this work are expected to help promote the development of better therapeutics of social cognitive impairments in schizophrenia and related psychiatric conditions.Systematic Review Registration[www.crd.york.ac.uk/prospero], identifier [CRD42021293224]. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Buddhist-Christian Studies 23 (2003) 139 [Access article in PDF] Japan Society for Buddhist-Christian Studies James W. Heisig Nanzan Institute for Religion and Culture The twenty-first annual meeting of the Japan Society for Buddhist-Christian Studies was held from July 24 to 26, 2002 at the Palace Side Hotel in Kyoto. The theme for the year was "The Body and Religion."Yoritomi Motohiro delivered a paper on "The Shingon View of (...) the Body," with a response by Keta Masako. Kosaka Kunutsugu's paper on "The Question of the Body in Nishida" was responded to by Tsuruoka Yoshio. Finally, Yagi Seiichi spoke on "The Body as a Locus of 'Oneness': Towards a Symbolic Representation of Basho Theory," with a response by James Heisig. As is the custom of the Society, lengthy discussions followed the papers.The interest generated by the topic was considerable, and it was decided to continue with it for at least one more year.In the past, the papers and discussions of the annual meetings have been published in the pages of Daijo Zen. This year the Society launched the publication of its own journal, Kenkyujo Shoho (Journal of the Japan Society for Buddhist-Christian Studies). The inaugural issue includes the papers from the 2001 meeting on "Nature." This journal is available from the Nanzan Institute for Religion and Culture, and may be downloaded for free from the Internet. Go to and follow the links under "Publications." The site also contains other information related to the Society and its past annual meetings.... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Japan Unbound: A Volatile Nation's Quest for Pride and PurposeDaniel A. MetrauxJapan Unbound: A Volatile Nation's Quest for Pride and Purpose. By John Nathan. Boston: Houghton Mifflin Company, 2004.Immediately after my return from an eight-day visit to Japan in late March 2004, I happened upon a long article in the New York Times (March 27, 2004, p. A4) featuring Hitomi Kanehara, a twenty-year-old author of a novel about (...) her post-bubble generation. Her portrait of a radically changing society in Japan reflects what I learned from two dozen interviews with Japanese friends and colleagues over the course of my visit.The Times article praised Kanehara for the portrait of young people in Japan since the 1990 collapse of Japan's "bubble economy" of the 1970s and 1980s:It is a world of "freeters," young Japanese surviving on part-time jobs and unconcerned with their future; of unsentimental sex and a profound inability to communicate verbally; a world in which a killing is viewed with amorality. The institutions that built postwar Japan—the family, school and companies—are noticeable by their absence. In a nation known for its social cohesion, the characters have no interest in playing a role in society, but only in finding personal satisfaction among themselves. Unlike Japanese in, say, their 30s, the characters in the novel are not disillusioned at Japanese society, since they had few expectations to begin with. "There are many people who don't expect anything from society," Ms. Kanehara says. "That's precisely why they are looking inward or to people [End Page 678] closest to them. I never knew the bubble era, so my way of looking at things can't help being different. Since I was born, I've never experienced a time of prosperity. Without my being aware, it's possible that my writing reflects the era."The Japan that I observed ever so briefly in March 2004 after a four-year absence is a society that is undergoing revolutionary changes in values and behavior in every sphere of life from education and popular culture to business and government. The result is a process that is radically changing the Japanese cultural landscape, making it a place vastly different from its traditional and even recent past.This view of Japan is carefully chronicled in John Nathan's most recent work, Japan Unbound: A Volatile Nation's Quest for Pride and Purpose. Nathan, the Takashima Professor of Japanese Cultural Studies at the University of California at Santa Barbara and author of highly praised books on Mishima Yukio and Sony, explores many facets of contemporary Japanese society ranging from education and families to business, politics, and foreign relations.Nathan analyzes a nation experiencing dramatic change as Japan moves away from many of its traditional values toward a very uncertain future. A long and demeaning recession has weakened the foundations of the traditional family system and has contributed to the rapid rise of divorce and an increase in the physical abuse of children by their families. The recession has contributed to the weakening of the bond between Japan's corporations and their employees, who are losing their right to lifetime employment. More and more Japanese are growing skeptical of their nation's dependant relationship of over a half-century with the United States, and nationalistic and xenophobic books are climbing up the best-seller list.One matter that Nathan discusses brilliantly is the traumatic breakdown of order and cohesion in Japan's primary and secondary schools and the increasingly rebellious nature of Japanese youth. He writes about riotous conditions in classrooms in a country once famous for respectful children. His best chapter depicts chaos in the classroom, where teachers across the country have simply lost control of their students. Disruptive students rule the roost, bringing intolerable disorder and engaging in physical attacks on other students as well as teachers and administrators. Nathan writes:Classroom breakdown is only part of a larger crisis of anger and withdrawal that has bewildered parents and educators.... In the United States, suspension is a legal option; in Japan suspension and expulsion are taboo under any circumstances. Promotion is based... (shrink)