Arguably, emotion is always valenced—either pleasant or unpleasant—and dependent on the pleasure system. This system serves adaptive evolutionary functions; relying on separable wanting, liking, and learning neural mechanisms mediated by mesocorticolimbic networks driving pleasure cycles with appetitive, consummatory, and satiation phases. Liking is generated in a small set of discrete hedonic hotspots and coldspots, while wanting is linked to dopamine and to larger distributed brain networks. Breakdown of the pleasure system can lead to anhedonia and other features of affective disorders. (...) Eudaimonia and well-being are difficult to study empirically, yet whole-brain computational models could offer novel insights potentially linking eudaimonia to optimal metastability in the pleasure system. (shrink)

This paper discusses J.S. Mill’s distinction between higher and lower pleasures, and suggests that recent neuroscientific evidence counts against it.

The pursuit of happiness is a preoccupation for many people — and probably has been ever since the emergence of Homo sapiens sapiens. The scientific understanding of the brain basis of happiness and its pursuit is, however, still in its infancy. Here we focus on recent scientific research on the closely related concepts of pleasure and desire, and discuss their underlying neural mechanisms and their roles in happiness. We also speculate on potential contributions of the brain's default networks to orchestrating (...) cognitive aspects of meaningfulness that are important to happiness. Finally, we discuss how the lack of pleasure, anhedonia, is a central feature of emotional disorders such as depression and thus perhaps the most important obstacle to happiness for many people. (shrink)

The pursuit of happiness is a preoccupation for many people — and probably has been ever since the emergence of Homo sapiens sapiens. The scientific understanding of the brain basis of happiness and its pursuit is, however, still in its infancy. Here we focus on recent scientific research on the closely related concepts of pleasure and desire, and discuss their underlying neural mechanisms and their roles in happiness. We also speculate on potential contributions of the brain's default networks to orchestrating (...) cognitive aspects of meaningfulness that are important to happiness. Finally, we discuss how the lack of pleasure, anhedonia, is a central feature of emotional disorders such as depression and thus perhaps the most important obstacle to happiness for many people. (shrink)

This article focuses on the substantial progress in understanding the psychology and neurobiology of sensory pleasure that has been made over the last decade. The link between pleasure and happiness has a long history in psychology. The growing evidence for the importance of affect in psychology and neuroscience shows a scientific account that involves hedonic pleasures and displeasures. A neurobiological understanding is required of how positive and negative effects are balanced in the brain. The article surveys developments in understanding brain (...) mechanisms of pleasure. It identifies a number of brain regions that are important in the brain's hedonic networks, and speculated on potential interaction with eudaimonic networks. The scientific study of pleasure and affect demonstrates the evolution of emotions and affective expressions, and suggests that these are adaptive responses to environmental situations. (shrink)