A central reason that undergirds the significance of evo-devo is the claim that development was left out of the Modern synthesis. This claim turns out to be quite complicated, both in terms of whether development was genuinely excluded and how to understand the different kinds of embryological research that might have contributed. The present paper reevaluates this central claim by focusing on the practice of model organism choice. Through a survey of examples utilized in the literature of (...) the Modern synthesis, I identify a previously overlooked feature: exclusion of research on marine invertebrates. Understanding the import of this pattern requires interpreting it in terms of two epistemic values operating in biological research: theoretical generality and explanatory completeness. In tandem, these values clarify and enhance the significance of this exclusion. The absence of marine invertebrates implied both a lack of generality in the resulting theory and a lack of completeness with respect to particular evolutionary problems, such as evolvability and the origin of novelty. These problems were salient to embryological researchers aware of the variation and diversity of larval forms in marine invertebrates. In closing, I apply this analysis to model organism choice in evo-devo and discuss its relevance for an extended evolutionary synthesis. (shrink)

Huxley coined the phrase, the “evolutionary synthesis” to refer to the acceptance by a vast majority of biologists in the mid-20th Century of a “synthetic” view of evolution. According to this view, natural selection acting on minor hereditary variation was the primary cause of both adaptive change within populations and major changes, such as speciation and the evolution of higher taxa, such as families and genera. This was, roughly, a synthesis of Mendelian genetics and Darwinian evolutionary theory; it (...) was a demonstration that prior barriers to understanding between various subdisciplines in the life sciences could be removed. The relevance of different domains in biology to one another was established under a common research program. The evolutionary synthesis may be broken down into two periods, the “early” synthesis from 1918 through 1932, and what is more often called the “modern synthesis” from 1936-1947. The authors most commonly associated with the early synthesis are J.B.S. Haldane, R.A. Fisher, and S. Wright. These three figures authored a number of important synthetic advances; first, they demonstrated the compatibility of a Mendelian, particulate theory of inheritance with the results of Biometry, a study of the correlations of measures of traits between relatives. Second, they developed the theoretical framework for evolutionary biology, classical population genetics. This is a family of mathematical models representing evolution as change in genotype frequencies, from one generation to the next, as a product of selection, mutation, migration, and drift, or chance. Third, there was a broader synthesis of population genetics with cytology, genetics, and biochemistry, as well as both empirical and mathematical demonstrations to the effect that very small selective forces acting over a relatively long time were able to generate substantial evolutionary change, a novel and surprising result to many skeptics of Darwinian gradualist views. The later “modern” synthesis is most often identified with the work of Mayr, Dobzhansky and Simpson. There was a major institutional change in biology at this stage, insofar as different subdisciplines formerly housed in different departments, and with different methodologies were united under the same institutional umbrella of “evolutionary biology.” Mayr played an important role as a community architect, in founding the Society for the Study of Evolution, and the journal Evolution, which drew together work in systematics, biogeography, paleontology, and theoretical population genetics. (shrink)

In this paper, I present an argument that quantitative behavioural analysis can be used in zoosemiotic studies to advance the field of biosemiotics. The premise is that signs and signals form patterns in space and time, which can be measured and analysed mathematically. Whole organism sign processing is an important component of the semiosphere, with individual organisms in their Umwelten deriving signs from, and contributing to, the semiosphere, and vice versa. Moreover, there is a wealth of data available in the (...) traditional ethology literature which can be reinterpreted semiotically and drawn together to make a cohesive biosemiotic whole. For example, isolated signals, such as structural elements of birdsong, are attributed meaning by an interpreter, thus generating new ideas and hypotheses in both biology and semiotics. Furthermore, animal behaviour science has developed numerous test paradigms that with careful adaptation, could be suitable for use within a Peircean tripartite model, and thus give valuable insights into Umwelten of other species. In my conclusion, I suggest that by bringing together traditional ethology and biosemiotics, it is possible to use the Modern Synthesis to provide context to biosemiosis, thus pragmatic meaning to animal signals. On this basis, I propose updating the Modern Synthesis to a Semiotic Modern Synthesis, which focuses on whole-organism signals and their contexts, the latter being derived from neo-Darwinian theory and the ‘Umwelt’. Thus, there need be no dichotomy; the Modern Synthesis can successfully be integrated with biosemiotics. (shrink)

In this paper, I will conduct three interrelated analyses. First, I will develop an analysis of various concepts in the history of biology that used to refer to individual-level phenomena but were then reinterpreted by the Modern Synthesis in terms of populations. Second, I argue that a similar situation can be found in contemporary biological theory. While different approaches reflect on the causal role of developing organisms in evolution, proponents of the Modern Synthesis avoid any substantial (...) change by reinterpreting and explaining individual-level phenomena from a population perspective. Finally, I will approach this debate by advocating the statistical reading of natural selection, which holds that explanations by natural selection are statistical. I will argue that the above historical conceptual reinterpretations belong to a new explanatory strategy developed by the Modern Synthesis based on population thinking. The reinterpretation of concepts at the individual level is part of the explanatory framework of the Modern Synthesis and the empty role of development within this framework. Moreover, the statistical perspective adopted here allows for the integration of two explanatory models: population-statistical and individual-causal. Finally, I will argue that this pluralistic framework can help to define the explanatory scope of the different biological approaches in order to achieve a coherent integration of development into evolution without rejecting population thinking. (shrink)

Epistasis plays an important role in the genetic architecture of common human diseases and can be viewed from two perspectives, biological and statistical, each derived from and leading to different assumptions and research strategies. Biological epistasis is the result of physical interactions among biomolecules within gene regulatory networks and biochemical pathways in an individual such that the effect of a gene on a phenotype is dependent on one or more other genes. In contrast, statistical epistasis is defined as deviation from (...) additivity in a mathematical model summarizing the relationship between multilocus genotypes and phenotypic variation in a population. The goal of this essay is to review definitions and examples of biological and statistical epistasis and to explore the relationship between the two. Specifically, we present and discuss the following two questions in the context of human health and disease. First, when does statistical evidence of epistasis in human populations imply underlying biomolecular interactions in the etiology of disease? Second, when do biomolecular interactions produce patterns of statistical epistasis in human populations?Answers to these two reciprocal questions will provide an important framework for using genetic information to improve our ability to diagnose, prevent and treat common human diseases. We propose that systems biology will provide the necessary information for addressing these questions and that model systems such as bacteria, yeast and digital organisms will be a useful place to start. BioEssays 27:637–646, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

Aristotle is oftentimes viewed through a strictly philosophical lens as heir to Plato and has having introduced logical rigor where an emphasis on the theory of Forms formerly prevailed. It must be appreciated that Aristotle was the son of a physician, and that his inculcation of the thought of other Greek philosophers addressing health and the natural elements led to an extremely broad set of biologically- and medically-related writings. As this article proposes, Aristotle deepened the fourfold theory of the elements (...) with anatomic and physiologic observations. In books like History of Animals, Parts of Animals, and the lost Anatomai, he actively dissected organisms and recorded his findings. The corpus of medically-related literature Aristotle developed had a direct influence on subsequent Greek thinkers, including Galen, and on Medieval Islamic and modern Western practitioners such as William Harvey. Aristotle's ideas continue to influence modern medical thinkers in Europe and America through both his interpretation by European philosophers gaining the attention of medical humanists, and his writings' enduring impact on medical researchers balancing scientific with more personalistic approaches to medicine. (shrink)

Journal of Human Values, Volume 28, Issue 3, Page 181-199, September 2022. The study addresses the challenging crisis of sustainable consumption. It explores the philosophy of Samkhya, which is based on nature and spirit, also found in Vedantic knowledge, and synthesizes it with the knowledge of spiritual well-being found in modern literature to conceptualize the roles of the direct, mediating and moderated mediation relationships of different Vedantic personality types, spiritual well-being and family structure with consciousness for sustainable consumption and (...) its three dimensions of environment, society and economy. Based on the conceptualized roles, different models have been proposed. (shrink)

The Modern Synthesis (MS) gene-centered population model of evolution is currently being challenged by the Extended Evolutionary Synthesis (ESS) organism-centered developmental model of evolution. The predictions of the EES are here examined with respect to the arguments of Edward Drinker Cope (1840–1897) for an organism-centered evolutionary process in which organisms both shape and are shaped by their environments such that the activities of the organisms themselves play a role in their own evolution.

The Extended Evolutionary Synthesis (EES) debate is gaining ground in contemporary evolutionary biology. In parallel, a number of philosophical standpoints have emerged in an attempt to clarify what exactly is represented by the EES. For Massimo Pigliucci, we are in the wake of the newest instantiation of a persisting Kuhnian paradigm; in contrast, Telmo Pievani has contended that the transition to an EES could be best represented as a progressive reformation of a prior Lakatosian scientific research program, with the (...) extension of its Neo-Darwinian core and the addition of a brand-new protective belt of assumptions and auxiliary hypotheses. Here, we argue that those philosophical vantage points are not the only ways to interpret what current proposals to ‘extend’ the Modern Synthesis-derived ‘standard evolutionary theory’ (SET) entail in terms of theoretical change in evolutionary biology. We specifically propose the image of the emergent EES as a vast network of models and interweaved representations that, instantiated in diverse practices, are connected and related in multiple ways. Under that assumption, the EES could be articulated around a paraconsistent network of evolutionary theories (including some elements of the SET), as well as models, practices and representation systems of contemporary evolutionary biology, with edges and nodes that change their position and centrality as a consequence of the co-construction and stabilization of facts and historical discussions revolving around the epistemic goals of this area of the life sciences. We then critically examine the purported structure of the EES—published by Laland and collaborators in 2015—in light of our own network-based proposal. Finally, we consider which epistemic units of Evo-Devo are present or still missing from the EES, in preparation for further analyses of the topic of explanatory integration in this conceptual framework. (shrink)

Over the past fifteen years there has been a considerable amount of debate concerning what theoretical population dynamic models tell us about the nature of natural selection and drift. On the causal interpretation, these models describe the causes of population change. On the statistical interpretation, the models of population dynamics models specify statistical parameters that explain, predict, and quantify changes in population structure, without identifying the causes of those changes. Selection and drift are part of a statistical description of population (...) change; they are not discrete, apportionable causes. Our objective here is to provide a definitive statement of the statistical position, so as to allay some confusions in the current literature. We outline four commitments that are central to statisticalism. They are: 1. Natural Selection is a higher order effect; 2. Trait fitness is primitive; 3. Modern Synthesis (MS)-models are substrate neutral; 4. MS-selection and drift are model-relative. (shrink)

Recent debates between proponents of the modern evolutionary synthesis (the standard model in evolutionary biology) and those of a possible extended synthesis are a good example of the fascinating tangle among empirical, theoretical, and conceptual or philosophical matters that is the practice of evolutionary biology. In this essay, we briefly discuss two case studies from this debate, highlighting the relevance of philosophical thinking to evolutionary biologists in the hope of spurring further constructive cross-pollination between the two (...) fields. (shrink)

The object of this paper is to reply to Morrison's ([2000]) claim that while ‘structural unity’ was achieved at the level of the mathematical models of population genetics in the early synthesis, there was explanatory disunity. I argue to the contrary, that the early synthesis effected by the founders of theoretical population genetics was unifying and explanatory both. Defending this requires a reconsideration of Morrison's notion of explanation. In Morrison's view, all and only answers to ‘why’ questions which (...) include the ‘cause or mechanism’ for some phenomenon count as explanatory. In my view, mathematical demonstrations that answer ‘how possibly’ and ‘why necessarily’ questions may also count as explanatory. The authors of the synthesis explained how evolution was possible on a Mendelian system of inheritance, answered skepticism about the sufficiency of selection, and thus explained why and how a Darwinian research program was warranted. While today we take many of these claims as obvious, they required argument, and part of the explanatory work of the formal sciences is providing such arguments. Surely, Fisher and Wright had competing views as to the optimal means of generating adaptation. Nevertheless, they had common opponents and a common unifying and explanatory goal that their mathematical demonstrations served. Introduction: Morrison's challenge Fisher v. Wright revisited The early synthesis Conclusion: unification and explanation reconciled. (shrink)

The argument that recent attempts to model technology studies on science studies have consequences for approaches to science studies as well is presented. In particular, the move to technology studies through science studies counts against the existing extreme pictures of science, "enlightenment rationalism," and "constructivisim," which are identified with modernism and postmodernism, respectively. Some components for a moderate "enlightened post-modern synthesis" in naturalism, interest theory, and systems theory are found.

The Reading Augustine series presents short, engaging books offering personal readings of St. Augustine of Hippo's contributions to western philosophical, literary, and religious life. This two-volume work provides a new understanding of Western subjectivity as theorized in the Augustinian Rule. A theopolitical synthesis of Antiquity, the Rule is a humble, yet extremely influential example of subjectivity production. In these volumes, Jodra argues that the Classical and Late-Ancient communitarian practices along the Mediterranean provide historical proof of a worldview in which (...) the self and the other are not disjunctive components, but mutually inclusive forces. The Augustinian Rule is a culmination of this process and also the beginning of something new: The paradigm of the monastic self as protagonist of the new, medieval worldview. Three main theoretical challenges leading to, and present in the Rule are tackled: What are the sources of our modern understanding of subjectivity? Can Ancient sources provide an alternative genealogy that resists the individualistic turn of Modernity? And can the commons be saved without suppressing individuality? Jodra seeks to prove that the synthesis-which is also an appropriation-of Greek and Judaic sources carried out by the first Christians allowed for two contrasting models of subjectivity, the self-less and the other-less, to 'take turns' to dominate our understanding of human nature. The Greek world provided the political dimension and the Jewish world established the key theological principles of a Mediterranean synthesis which took place in Rome. Coherently and progressively, Jodra emphasizes the theopolitical nature of our worldview even today, and claim that the subject of the primitive Church is its most visible incarnation. These volumes therefore restore the unity of the Hellenistic and Judaic world as found by the first Christians, proving that the self and the other are two essential pieces in the construction of our world. (shrink)

Charney's target article continues a critique of genetic blueprint models of development that suggests reconsideration of concepts of adaptation, inheritance, and environment, which can be well illustrated in current research on infant attachment. The concepts of development and adaptation are so heavily based on the model of genetics and inheritance forged in the modern synthesis that they will require reconsideration to accommodate epigenetic inheritance.

Chance has been a focus of attention ever since the beginning of population genetics, but neutrality has not, as natural selection once appeared to be the only worthwhile issue. Neutral change became a major source of interest during the neutralist–selectionist debate, 1970–1980. It retained interest beyond this period for two reasons that contributed to its becoming foundational for evolutionary reasoning. On the one hand, neutral evolution was the first mathematical prediction to emerge from Mendelian inheritance: until then evolution by natural (...) selection was considered the alternative to the fixity of species; now it appears to be the alternative to continuous change. Second, neutral change generated a set of clear predictions on standing variation. These could be used as a reference for detecting more elusive alternative mechanisms of evolution including natural selection. In the wake of the transition from Mendelism to genomics, the combination of coalescent theory, DNA sequence variation, and numerical analysis made it possible to integrate contingent aspects of the history of species into a new null model, thus opening a new dimension in the concept of population that the Modern Synthesis formerly considered as a mere gene pool. (shrink)

Research in science studies supports a vision of the world as an endlessly lively and emergent place. This essay briefly notes a range of philosophical and scientific positions that elaborate cognate ontologies, but I dwell at greater length on a variety of objects and practices that, in contrast to the modern sciences, thematise, foreground and stage emergence for us. Drawn from the history of cybernetics these span the fields of robotics, organisations and management, the arts and architecture. Noting the (...) eruption of cybernetics into many different fields, I suggest that its history offers a model for an antidisciplinary synthesis that dissolves conventional boundaries within and beyond the academic sphere. I characterise the political valence of this synthetic assemblage in terms of Martin Heidegger's contrast between projects of enframing and revealing. (shrink)

There is a conceptual crisis in the biomedical sciences that is particularly salient in psychopathology research. Underlying the crisis is a controversy that pertains to the current medical model of disease that largely draws from causal-mechanistic explanations. The bedrock of this model is the analysis of biological part-dysfunctions that aims at unequivocally defining a pathological condition and demarcating it from its neighboring entities. This endeavor has led to a quest for physiological, biochemical, and genetic signatures. Yet, so far (...) there is little evidence for reliable biomarkers for any mental disorder. The contemporary biomedical paradigm largely ignores historical, dynamic, and system-level aspects—a view that has contributed much to the conceptual disjunction of the patient as a person from his/her disease. Notwithstanding the impressive progress in the biomedical sciences, increasingly more critics question whether the constituting framework is sufficient to convey a comprehensive understanding of illnesses, especially mental illnesses. Thus, the medical model urgently requires an update. But rather than revamping it by methodological advancements, it will be necessary to critically review its philosophical roots. The most problematic issues that require reworking are: the preponderance of the biostatistical theory; the undue decoupling of physiological from evolutionary explanations of function; the clinging to the Modern Synthesis ; and the neglect of dynamic and system-level properties. The proposed overhaul requires the heeding of historical explanations that draw from the Extended Evolutionary Synthesis as well as systems biology approaches for tackling multilevel and dynamic phenomena of complex systems. (shrink)

In this book, Nicolas Laos studies the meaning of the terms "world" and "order," the moral dimensions of each world order model, and wider issues of meaning and interpretation generated by humanity's attempt to live in a meaningful world and to find the logos of the beings and things in the world. The aim of this book is to propose a unified theory of world order (i.e., a theory that combines philosophy, theology, and political theory). In this context, the (...) author provides a thought-provoking (re)interpretation of classical philosophy (placing particular emphasis on Platonism), an in-depth inquiry into medieval philosophy and spirituality (placing particular emphasis on the cultural differences between the Greek East and the Latino-Frankish West), and an intellectually challenging review and evaluation of modern Western philosophy (including Descartes, Spinoza, Leibniz, Locke, Berkeley, Hume, Rousseau, Kant, Hegel, Kierkegaard, Husserl, and Heidegger) and of Nietzsche's and the postmodernists' revolt against modernity. He then elucidates the philosophical foundations and "pedigree" of each of the three basic political theories of modernity (i.e., Liberalism, Communism, and Fascism), and he studies the basic theoretical debates in International Relations, Geopolitics, and Noopolitics. Finally, Laos proposes a new, "fourth," political theory which he calls "metaphysical republicanism.". (shrink)

The theory of constructive (recursive) models follows from works of Froehlich, Shepherdson, Mal'tsev, Kuznetsov, Rabin, and Vaught in the 50s. Within the framework of this theory, algorithmic properties of abstract models are investigated by constructing representations on the set of natural numbers and studying relations between algorithmic and structural properties of these models. This book is a very readable exposition of the modern theory of constructive models and describes methods and approaches developed by representatives of the Siberian school of (...) algebra and logic and some other researchers (in particular, Nerode and his colleagues). The main themes are the existence of recursive models and applications to fields, algebras, and ordered sets (Ershov), the existence of decidable prime models (Goncharov, Harrington), the existence of decidable saturated models (Morley), the existence of decidable homogeneous models (Goncharov and Peretyat'kin), properties of the Ehrenfeucht theories (Millar, Ash, and Reed), the theory of algorithmic dimension and conditions of autostability (Goncharov, Ash, Shore, Khusainov, Ventsov, and others), and the theory of computable classes of models with various properties. Future perspectives of the theory of constructive models are also discussed. Most of the results in the book are presented in monograph form for the first time. The theory of constructive models serves as a basis for recursive mathematics. It is also useful in computer science, in particular, in the study of programming languages, higher level languages of specification, abstract data types, and problems of synthesis and verification of programs. Therefore, the book will be useful for not only specialists in mathematical logic and the theory of algorithms but also for scientists interested in the mathematical fundamentals of computer science. The authors are eminent specialists in mathematical logic. They have established fundamental results on elementary theories, model theory, the theory of algorithms, field theory, group theory, applied logic, computable numberings, the theory of constructive models, and the theoretical computer science. (shrink)

The subject of the research is a modern graphic and communicative design, in the context of changing existing and forming new roles of communicators, transforming the communication model, forming a semiotic communication format. The object of the research is modern graphic and communicative design, as well as their traditional, digital and generative subdirections. Design beginning to have digital, semiotic-interactive and artificially intelligent characteristics. The author examines in detail such aspects of the topic as: dialogical, semiotic-interactive qualities of (...) design solutions; digital, semiotic-interactive design-software expressive means; features of semiotic-deconstructivity (analyticity) and semiotic-synthetics (constructiveness) of design solutions in the context of design activity; the influence of technical and technological features of tools and design-environments (design systems) for the formation of automated and artificially intelligent qualities of design solutions. The study of the conceptual model of a semiotic-interactive design is carried out in the context of a semiotic-interactive methodology (a set of principles and strategies of design activity). The main conclusions of the study are the description of the conceptual model of a semiotic-interactive design solution, in the context of a semiotic-interactive methodology implemented in the conceptual-generative subdirection of modern graphic and communicative design. The author's main contribution to the research of the topic is to identify the main components of the conceptual model of a semiotic-interactive design solution and demonstrate their relationship with each other in the form of a holistic model. The novelty of the research lies in the description of the characteristics of the components, the conceptual model of a semiotic-interactive design solution: a dialogical semiotic-interactive format for creating invariant concepts and design solutions; versioning of design solutions based on the semiotic synthesis of design programs; semiotic deconstruction of design solutions at the macro and micro levels; semiotic synthesis of design and artistic design programs; application of design programs as decision tools; use of hyperconnected capabilities of the design environment: the history of actions, integrity and continuous change and development. (shrink)

8 lectures plus extracts and notes (CW 286) This collection introduces Rudolf Steiner's vision of architecture as a culmination of the arts. Such architecture unites sculpture, painting, and engraving as well as drama, music and dance--a vital synthesis of all the arts working in cooperation through the common ideal of awakening us to our individuality and task in life. Unlike many of his contemporaries, Steiner's ideas did not remain abstract. Within his lifetime he was able to design and construct (...) a number of buildings, including his architectural masterpiece, the Goetheanum--a center for culture and arts near Basle, Switzerland. In these lectures Steiner describes, with reference to the Goetheanum, the importance of an architecturally coherent and integrated community, and how this in turn affects social unity and harmony. These lectures offer a panorama of the development of architecture in parallel with the emerging human soul in human evolution. This is a valuable collection for all students of architecture, the arts, social science, and those looking for a deeper spiritual understanding of the art of architecture. Includes eight color plates and 30 black & white illustrations. CONTENTS: Part One: The Temple Is the Human Being An Art & Architecture that Reveal the Underlying Wholeness of Creation The Task of Modern Art & Architecture Proposals for the Architecture of a Model Anthroposophical Community at Dornach Part Two: Ways to a New Style of Architecture True Artistic Creation Art As the Creation of Organs through which the Gods Speak to Us A New Concept of Architecture The Aesthetic Laws of Form The Creative World of Color Appendix: The Evolution of Architecture at the Turn of Each New Millennium Notes & Color Plates Architecture as a Synthesis of the Arts is a translation from German of Wege zu einem neuen Baustil. "Und der Bau wird Mensch". (shrink)

Three types of unification patterns in the history of physics are considered. The paradigmatic example of synthesis is chosen to be Maxwell’s fusion of electricity, magnetism and light. The analysis of Maxwell’s works enables to extract three hallmarks of any successful scientific unification. The hallmarks appear to be crucial since any violation of them inevitably leads to a radical decrease of the unifying theory’s predictive power. It is contended that classical (Maxwell) and modern (Einstein) milestones of physics growth (...) are in good agreement with the rules extracted. However, all the three basic stages of ‘post-modern’ physics – i.e. the electroweak theory of Weinberg and Salam, GUTs and SUSY approach culminating in the superstrings – can be described as violations of the synthesis rules. (shrink)

During the first decades of the 20th century, many anthropologists who had previously adhered to a linear view of human evolution, from an ape via Pithecanthropus erectus and Neanderthal to modern humans, began to change their outlook. A shift towards a branching model of human evolution began to take hold. Among the scientific factors motivating this trend was the insight that mammalian evolution in general was best represented by a branching tree, rather than by a straight line, and (...) that several new fossil hominids were discovered that differed significantly in their morphology but seemed to date from about the same period. The ideological and practical implications of imperialism and WWI have also been identified as formative of the new evolutionary scenarios in which racial conflict played a crucial role. The paper will illustrate this general shift in anthropological theory for one particular scientist, William Sollas. Sollas achieved a synthesis of human morphological and cultural evolution in what I will refer to as an imperialist model. In this theoretical framework, migration, conflict, and replacement became the main mechanisms for progress spurred by 'nature's tyrant,' natural selection. (shrink)

The paradox marking Spinoza’s reappearance in modernity is well known. If Mendelssohn wished to “give him new credence by bringing him closer to the philosophical orthodoxy of Leibniz and Wolff,” and Jacobi, “by presenting him as a heterodox figure in the literal sense of the term, wanted to do away with him definitively for modern Christianity”—well, “both failed in their goal, and it was the heterodox Spinoza who was rehabilitated.” The Mendelssohn-Jacobi debate can be grafted onto the crisis of (...) a specific philosophical model. It generates a figure of Spinoza capable of assuaging the exacerbated spiritual tension of that epoch, and of constituting the systematic preamble of the relation between power and substance—between subject and nature. Spinoza, the damned Spinoza, had a resurgence in modernity as a Romantic philosopher. Lessing won out by recognizing in Spinoza an idea of nature which was capable of balancing the relation between feeling and intellect, freedom and necessity, and history and reason. Herder and Goethe, against the subjective and revolutionary impatience of the Sturm und Drang, based themselves on this powerful image of synthesis and recomposed objectivity: Spinoza is not only the figure of Romanticism; he constitutes its grounding and its fulfillment. The omnipotence of nature was no longer to break off into the tragedy of feeling, but it was to triumph over it, by opposing it to a kingdom of completed forms. Spinoza’s first reception within Romanticism was thus an aesthetic reception, a perception of motion and perfection, of dynamism and forms. And it remained such, even when the general frame and the particular components of Romanticism were subjected to the labor of philosophical critique. Fichte, the real philosophical hero of Romanticism, considered both Spinoza’s and Kant’s systems to be “perfectly coherent,” in the incessant ontological movement of the I. For the Schelling of the 1790s, the assertion of a radical opposition between 1 critical philosophy and dogmatic philosophy—that is, between a philosophy of the absolute I founding itself on the critical philosophy and a dogmatic philosophy of the absolute object and Spinozism—was quickly resolved into an analysis of action which dialectically took on the weight of the objective. Far from becoming antinomial, the absolute position of the I composes itself into a necessary process which, above tragedy, exalts the “spiritual automatism” of the relation between subject and substance. The aesthetic dimension of this synthesis consists in ceaselessly and tirelessly bringing back power and substance, the productive element and the form of production, to perfection. Romanticism, according to Hegel, is characterized by a capacity to overcome the pure objectivity of the ideal and the natural as a true idea of beauty and truth, initially to destroy the union of the idea and its reality, and to locate the latter in the difference, so as then to bring to manifestation the inner world of absolute subjectivity and reconstruct its objectivity where the overcoming of sensibility is appeased in the absolute character of the result. The filiation of this process is still Lessingian, but the new dialectic expresses and articulates its motivations, while insisting on the propaedeutic of the beautiful along the path leading to the absolute. Spinoza, a certain Spinoza, becomes the central figure in this process. (shrink)

The paradox marking Spinoza’s reappearance in modernity is well known. If Mendelssohn wished to “give him new credence by bringing him closer to the philosophical orthodoxy of Leibniz and Wolff,” and Jacobi, “by presenting him as a heterodox figure in the literal sense of the term, wanted to do away with him definitively for modern Christianity”—well, “both failed in their goal, and it was the heterodox Spinoza who was rehabilitated.” The Mendelssohn-Jacobi debate can be grafted onto the crisis of (...) a specific philosophical model. It generates a figure of Spinoza capable of assuaging the exacerbated spiritual tension of that epoch, and of constituting the systematic preamble of the relation between power and substance—between subject and nature. Spinoza, the damned Spinoza, had a resurgence in modernity as a Romantic philosopher. Lessing won out by recognizing in Spinoza an idea of nature which was capable of balancing the relation between feeling and intellect, freedom and necessity, and history and reason. Herder and Goethe, against the subjective and revolutionary impatience of the Sturm und Drang, based themselves on this powerful image of synthesis and recomposed objectivity: Spinoza is not only the figure of Romanticism; he constitutes its grounding and its fulfillment. The omnipotence of nature was no longer to break off into the tragedy of feeling, but it was to triumph over it, by opposing it to a kingdom of completed forms. Spinoza’s first reception within Romanticism was thus an aesthetic reception, a perception of motion and perfection, of dynamism and forms. And it remained such, even when the general frame and the particular components of Romanticism were subjected to the labor of philosophical critique. Fichte, the real philosophical hero of Romanticism, considered both Spinoza’s and Kant’s systems to be “perfectly coherent,” in the incessant ontological movement of the I. For the Schelling of the 1790s, the assertion of a radical opposition between 1 critical philosophy and dogmatic philosophy—that is, between a philosophy of the absolute I founding itself on the critical philosophy and a dogmatic philosophy of the absolute object and Spinozism—was quickly resolved into an analysis of action which dialectically took on the weight of the objective. Far from becoming antinomial, the absolute position of the I composes itself into a necessary process which, above tragedy, exalts the “spiritual automatism” of the relation between subject and substance. The aesthetic dimension of this synthesis consists in ceaselessly and tirelessly bringing back power and substance, the productive element and the form of production, to perfection. Romanticism, according to Hegel, is characterized by a capacity to overcome the pure objectivity of the ideal and the natural as a true idea of beauty and truth, initially to destroy the union of the idea and its reality, and to locate the latter in the difference, so as then to bring to manifestation the inner world of absolute subjectivity and reconstruct its objectivity where the overcoming of sensibility is appeased in the absolute character of the result. The filiation of this process is still Lessingian, but the new dialectic expresses and articulates its motivations, while insisting on the propaedeutic of the beautiful along the path leading to the absolute. Spinoza, a certain Spinoza, becomes the central figure in this process. (shrink)

Ernst Mayr (1980) provided an influential picture of the nature of the Modern Evolutionary Synthesis and of the debate and changes occurring prior to its completion. Mayr intended his account to be applicable to comparable cases. Sociobiology should be evaluated both as a comparable case, an attempt to produce a synthesis which undergoes development of the sort Mayr described, and as an extension of the Modern Synthesis itself. Examination of what the explanatory goals and development (...) of the New Sociobiological Synthesis would be, if it is to achieve a fruitful synthesis which fits Mayr's account, undermines Richard Lewontin's critique of sociobiology. Although Lewontin speaks for many in viewing sociobiology as the latest historical manifestation of social Darwinism, genetic determinism, biological reductionism, and vulgar adaptationism, sociobiology's effort to produce a synthesis does not entail commitment to those positions. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Judgement and Sense in Modern French Philosophy: A New Reading of Six Thinkers by Henry Somers-HallClayton CrockettSOMERS-HALL, Henry. Judgement and Sense in Modern French Philosophy: A New Reading of Six Thinkers. Cambridge: Cambridge University Press, 2022. 264 pp. Cloth, $99.99Henry Somers-Hall's book examines how French philosophers in the twentieth century develop a logic of thinking based on sense that is both influenced by but also counters (...) Kant's paradigm of thinking, which is based on judgment. Beginning with Kant and German idealism, including the German responses to Kant in the work of Hölderlin, Fichte, Schelling, and Hegel, this book then carefully draws out the ways that Bergson, Sartre, Merleau-Ponty, Derrida, Foucault, and Deleuze all work against this understanding of thinking as judging by showing how our experience and our thought precede the categories of judgment.In chapter 1, Somers-Hall carefully sets out Kant's model of thinking and shows how the categories of philosophical thought are fundamentally based on how we judge our sensible intuitions. Judgment is at the center of Kant's thought, and this is apparent in the Critique of Pure Reason, including the famous Transcendental Deduction. Our knowledge has a legislative function in relation to objects, and conscious synthesis takes the form of a judgment. Despite their criticisms of Kant, later German idealists do not fundamentally depart from this modality of judgment that takes place at the center of their philosophy. Even though they put Kant's concepts in motion, it remains a structure of judgment that is understood as dynamic.Chapter 2 turns to Bergson, to show how his emphasis on immediate experience precedes categorical judgement. Bergson distinguishes between temporal and spatial multiplicities, and argues that temporal multiplicities that are expressed in terms of duration underlie the spatial ones that contribute to judgment. Duration is a deeper experience of time that is associated with life. Somers-Hall in chapter 3 examines Sartre's writings on imagination to show how consciousness is a pure relation and an affective mode of thinking that underlies the categorial mode of judgment.Most of these French philosophers develop their accounts of noncategorial sense in either explicit or implicit relation to Kant's philosophy. Merleau-Ponty is no exception, and in chapter 4 we see how it is the organization of perception that gives sense to the world, and this precedes and generates "our reflective categories of judgement." Judgment emerges out of perception, although Merleau-Ponty grounds perception in the embodied person. Derrida does not ground sense or [End Page 365] thinking in a body, but looks for noncategorial grounds that make possible "surface structures of thinking." In chapter 5, Somers-Hall elaborates Derrida's famous nonconcept of différance, which underlies and makes possible our concepts of voice and writing that appear to be oppositions but in fact are not because they rely on each other. Différance is not a concept; it is prior to conceptual determination, and it "operates as an 'origin' that has none of the traits of the structure of judgement."Foucault relies on Kant for his three epistemes of resemblance, representation, and the human being, modern man. Chapter 6 shows how Foucault is concerned in both his archaeology and his genealogy with opening up the structures of power that make any juridical ordering possible. Here a productive biopower works beneath what we recognize more explicitly as "juridico-discursive power" in both positive and negative ways that escape the grasp of a philosophy that is solely based on judgment.In chapter 7 Somers-Hall shows how Deleuze's concept of intensity underlies all forms of representational judgment. Intensity operates according to a process of differentiation that produces a logic of sense, which we miss when we grasp onto a "dogmatic image of thought" that "prevents a genuine encounter with the world [that] conditions us to understand it in terms of unified subjects who make sense of the world in terms of judgements." We think in response to a shock or an encounter with something in the world that forces us to think and to make sense. We form judgments retroactively, by reducing differences to... (shrink)

This paper surveys questions about the nature of the Modern Synthesis as a historical event : was it rather theoretical than institutional? When and where did it actually happen? Who was involved? It argues that all answers to these questions are interrelated, and that systematic sets of answers define specific perspectives on the Modern Synthesis that are all complementary.

This paper locates the contributions of Kauffman and Ayala to this symposium in the context of recent discussions of the adequacy of the Modern Synthesis. The neglect of morphology and development described by Kauffman is understandable in view of the belief that selection is the most powerful evolutionary force. His idea that properties of order may be explained by nonselective mechanisms is also examined. The paper subsequently takes up Ayala's criticism of S.J. Gould's view that macroevolution is a (...) process "decoupled" from microevolution. It is argued that the idea of species selection makes Gould's antireductionism ontological in character; this contrasts with Ayala's contention that the decoupling is merely epistemological. (shrink)

The Modern Synthesis has dominated biology for 80 years. It was formulated in 1942, a decade before the major achievements of molecular biology, including the Double Helix and the Central Dogma. When first formulated in the 1950s these discoveries and concepts seemed initially to completely justify the central genetic assumptions of the Modern Synthesis. The Double Helix provided the basis for highly accurate DNA replication, while the Central Dogma was viewed as supporting the Weismann Barrier, so (...) excluding the inheritance of acquired characteristics. This article examines the language of the Modern Synthesis and reveals that it is based on four important misinterpretations of what molecular biology had shown, so forming the basis of the four Illusions: 1. Natural Selection; 2. The Weismann Barrier; 3. The Rejection of Darwin’s Gemmules; 4. The Central Dogma. A multi-level organisation view of biology avoids these illusions through the principle of biological relativity. Molecular biology does not therefore confirm the assumptions of the Modern Synthesis. (shrink)

In 1937, just as Dobzhansky published the book that later generations would laud as the foundation of the modern synthesis, the American Naturnlist published a symposium on "supraspecific variation in nature and in classification." Alfred C. Kinsey, who later became one of America's most controversial intellectuals for his study of basic behaviors in another sort of WASP,1 led off the symposium with a summary of his extensive work on a family of gall wasps, the Cynipidae. In his article, (...) Kinsey strongly advocated the central theme of the developing synthesis: Evolution at all scales, particularly macroevolution, could be explained by the genetic mechanisms observed in laboratories and local populations. He first complained that some geneticists and naturalists were still impeding a synthesis with their insistence upon causal separation of levels: "Just as some of the geneticists have insisted that the laboratory genetics may explain the nature and origin of Mendelian races, but not of natural species, so others indicate that the qualities of higher categories must be explained on bases other than those involved in species" (1937, p. 208). He then defended the central postulate. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy of Music Education Review 13.1 (2005) 104-108 [Access article in PDF] A Response to Estelle R. Jorgensen, "Four Philosophical Models of the Relationship Between Theory and Practice" Randall Everett Allsup Teachers College, Columbia University Each of the four philosophical models that Estelle Jorgensen has put forth contests, adheres to, or adjusts the hierarchical relationships between dualities, specifically the theory and practice of musical learning. The dichotomy model (...) faces binary associations head on, splitting existence however defined into dualisms like "this/that," "us/them," and "mind/body." Models of polarity, according to Jorgensen, accommodate dualities by buffering edges, emphasizing the interconnectedness of binary relationships. The fusion metaphor is exemplified by Paulo Freire's notion of praxis in which action and reflection are welded together to create hope for a new world, one free of the oppression and conflict that is inherent in binary relationships. The dialectical model is contrapuntal by nature, Edward Said would say.1This relationship highlights our postmodern devotion to différence by embracing the tension created through inclusion so that "this is with that," "we are with them and they are with us," and "mind is with body, just as body is with mind."2Perhaps there is a fifth model, a new kind of relationship where the oppositional or hierarchical nature of binaries co-exists peacefully without tension. [End Page 104] Such an arrangement is, I think, an outgrowth of capitalist democracy—it is, most especially, representative of our global, information age. This type of relationship is problematic philosophically, we will see, lacking as Jorgensen has outlined "logic evidenced in principles," "internal consistency," and "coherence within a unity or whole." Likewise for Bennett Reimer, this new mind-set fails the test of philosophical scrutiny, unconcerned as it is with a "reasoned, structured set of propositions."3 Whether philosophy or mind-set, this new arrangement has as much to do with freedom and free markets as it does with the particular conditions of both modernity and postmodernity.In the novel, White Noise, by Don DeLillo, the postmodern condition is represented in part by an "Airborne Toxic Event," a cloud of gas, Nyodene D, which floats above a tranquil All-American college town.4 A sense of crisis is felt, but felt obliquely and no one knows exactly what harm has been done. In Albert Camus' The Plague, by contrast, the disease that infests the North African town of Oran acts to awaken its citizenry, confronting the populace with the moral imperatives to fight or flee.5 Perhaps the metaphor of quarantine symbolizes the hard boundaries of modernism.Capitalism seeks to dissolve conflict. It operates silently, in the realm of social production, like a cloud of gas. Denise, Jack Gladney's daughter in White Noise, mumbles over and over in her sleep, "Toyota Corolla, Toyota Celica, Toyota Cressida...."6 There is a sense of ontological change, that the expanding reach of media, information, and technology rewires the way we think, the way we dream. Tensions are willed away. The expansion and survival of market shares, after all, depend on the peaceful erosion of boundaries—boundaries that demarcate what we learn, what we buy, and who we are.Questions about what this new system means—this new mind-set—are explored in a book called Empire by Michael Hardt and Antonio Negri.7 These writers posit a global world of communication, cooperation, and affect, where an increase in hybrids creates a kind of "omniversality" where the virtual, natural, and ideological converge.8 In the dialectical relationship that Jorgensen shares with writers like Paulo Freire and Maxine Greene, there is no acceptable synthesis, no peaceful co-existence, between oppressors and oppressed. While according to Freire, the oppressed may internalize or house characteristics of the oppressor. In the global world of capital, the oppositional nature of the Other is replaced by niches or fragments, dissolving differences into marketing opportunities, really. That the avant-garde no longer exists is proof of this new state.As the essentialist nature of the Other fades away... (shrink)

This book compiles and reviews the most prominent linguistic theories into a single source that serves as an essential reference for future solutions to one of the most important challenges of our age.

The modern synthesis in evolutionary biology is taken to be that period in which a consensus developed among biologists about the major causes of evolution, a consensus that informed research in evolutionary biology for at least a half century. As such, it is a particularly fruitful period to consider when reflecting on the meaning and role of chance in evolutionary explanation. Biologists of this period make reference to “chance” and loose cognates of “chance,” such as: “random,” “contingent,” “accidental,” (...) “haphazard,” or “stochastic.” Of course, what an author might mean by “chance” in any specific context varies. -/- In the following, we first offer a historiographical note on the synthesis. Second, we introduce five ways in which synthesis authors spoke about chance. We do not take these to be an exhaustive taxonomy of all possible ways in which chance meaningfully figures in explanations in evolutionary biology. These are simply five common uses of the term by biologists at this period. They will serve to organize our summary of the collected references to chance and the analysis and discussion of the following questions: • What did synthesis authors understand by chance? • How did these authors see chance operating in evolution? • Did their appeals to chance increase or decrease over time during the synthesis? That is, was there a “hardening” of the synthesis, as Gould claimed (1983)? (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy of Music Education Review 13.1 (2005) 104-108 [Access article in PDF] A Response to Estelle R. Jorgensen, "Four Philosophical Models of the Relationship Between Theory and Practice" Randall Everett Allsup Teachers College, Columbia University Each of the four philosophical models that Estelle Jorgensen has put forth contests, adheres to, or adjusts the hierarchical relationships between dualities, specifically the theory and practice of musical learning. The dichotomy model (...) faces binary associations head on, splitting existence however defined into dualisms like "this/that," "us/them," and "mind/body." Models of polarity, according to Jorgensen, accommodate dualities by buffering edges, emphasizing the interconnectedness of binary relationships. The fusion metaphor is exemplified by Paulo Freire's notion of praxis in which action and reflection are welded together to create hope for a new world, one free of the oppression and conflict that is inherent in binary relationships. The dialectical model is contrapuntal by nature, Edward Said would say.1This relationship highlights our postmodern devotion to différence by embracing the tension created through inclusion so that "this is with that," "we are with them and they are with us," and "mind is with body, just as body is with mind."2Perhaps there is a fifth model, a new kind of relationship where the oppositional or hierarchical nature of binaries co-exists peacefully without tension. [End Page 104] Such an arrangement is, I think, an outgrowth of capitalist democracy—it is, most especially, representative of our global, information age. This type of relationship is problematic philosophically, we will see, lacking as Jorgensen has outlined "logic evidenced in principles," "internal consistency," and "coherence within a unity or whole." Likewise for Bennett Reimer, this new mind-set fails the test of philosophical scrutiny, unconcerned as it is with a "reasoned, structured set of propositions."3 Whether philosophy or mind-set, this new arrangement has as much to do with freedom and free markets as it does with the particular conditions of both modernity and postmodernity.In the novel, White Noise, by Don DeLillo, the postmodern condition is represented in part by an "Airborne Toxic Event," a cloud of gas, Nyodene D, which floats above a tranquil All-American college town.4 A sense of crisis is felt, but felt obliquely and no one knows exactly what harm has been done. In Albert Camus' The Plague, by contrast, the disease that infests the North African town of Oran acts to awaken its citizenry, confronting the populace with the moral imperatives to fight or flee.5 Perhaps the metaphor of quarantine symbolizes the hard boundaries of modernism.Capitalism seeks to dissolve conflict. It operates silently, in the realm of social production, like a cloud of gas. Denise, Jack Gladney's daughter in White Noise, mumbles over and over in her sleep, "Toyota Corolla, Toyota Celica, Toyota Cressida...."6 There is a sense of ontological change, that the expanding reach of media, information, and technology rewires the way we think, the way we dream. Tensions are willed away. The expansion and survival of market shares, after all, depend on the peaceful erosion of boundaries—boundaries that demarcate what we learn, what we buy, and who we are.Questions about what this new system means—this new mind-set—are explored in a book called Empire by Michael Hardt and Antonio Negri.7 These writers posit a global world of communication, cooperation, and affect, where an increase in hybrids creates a kind of "omniversality" where the virtual, natural, and ideological converge.8 In the dialectical relationship that Jorgensen shares with writers like Paulo Freire and Maxine Greene, there is no acceptable synthesis, no peaceful co-existence, between oppressors and oppressed. While according to Freire, the oppressed may internalize or house characteristics of the oppressor. In the global world of capital, the oppositional nature of the Other is replaced by niches or fragments, dissolving differences into marketing opportunities, really. That the avant-garde no longer exists is proof of this new state.As the essentialist nature of the Other fades away... (shrink)

The paper discusses the Kantian legacy in modern views about scientific theories. The aim of this paper is to show how Einstein's philosophy of science, which was inspired by his physics, offers a specialized version of the Kantian synthesis of Empiricism and Rationalism. In modern physical theories Kant's a priori conditions become “constraints,” as shown in Einstein's use of principle theories. Einstein's use of principle theories shows how constraints are used to steer the mapping of the rational (...) onto the empirical elements of scientific theories. (shrink)

The paper discusses the Kantian legacy in modern views about scientific theories. The aim of this paper is to show how Einstein's philosophy of science, which was inspired by his physics, offers a specialized version of the Kantian synthesis of Empiricism and Rationalism. In modern physical theories Kant's a priori conditions become “constraints,” as shown in Einstein's use of principle theories. Einstein's use of principle theories shows how constraints are used to steer the mapping of the rational (...) onto the empirical elements of scientific theories. (shrink)

Since its origin in the early 20th century, the modern synthesis theory of evolution has grown to represent the orthodox view on the process of organic evolution. It is a powerful and successful theory. Its defining features include the prominence it accords to genes in the explanation of development and inheritance, and the role of natural selection as the cause of adaptation. Since the advent of the 21st century, however, the modern synthesis has been subject to (...) repeated and sustained challenges. In the last two decades, evolutionary biology has witnessed unprecedented growth in the understanding of those processes that underwrite the development of organisms and the inheritance of characters. The empirical advances usher in challenges to the conceptual foundations of evolutionary theory. Many current commentators charge that the new biology of the 21st century calls for a revision, extension, or wholesale rejection of the modern synthesis theory of evolution. Defenders of the modern synthesis maintain that the theory can accommodate the exciting new advances in biology, without forfeiting its central precepts. The original essays collected in this volume—by evolutionary biologists, philosophers of science, and historians of biology—survey and assess the various challenges to the modern synthesis arising from the new biology of the 21st century. Taken together, the essays cover a spectrum of views, from those that contend that the modern synthesis can rise to the challenges of the new biology, with little or no revision required, to those that call for the abandonment of the modern synthesis. (shrink)

Introduction. According to the well-established opinion of specialists in social sciences and humanities, a person diffracts his selves in the modern world: real spaces (professions, statuses) and virtual (accounts, profiles). In the diffraction of a person through spaces of different order, each “new” self acquires relative autonomy (a trace of the self in the network, which is present regardless of the attitude to it), and at the same time there remains the connection that, as it were, keeps the self (...) with his digital images and “prints”. The main questions of the article are: in what relation and in relation to what is it possible to talk about the identity of a modern person; what fundamentally significant do the researches on human identity give us today; what do those who ask questions about personal identity in the digital age focus their attention on? In order to answer these questions, let us turn to scientific articles from domestic and foreign journals. This article presents the analytics of publications from Scopus and RSCI databases, in which the problem of personal identity is posed. The purpose of the article is to analyze scientific publications on human identity and summarize the main ideas presented in those publications. Methods. The research is based on general scientific methods, analysis and synthesis, induction, deduction, and abstraction. The author analyzes scientific publications on the basis of the interpretation method and a systematic approach method. Content analysis was used as a method, but it was used within the scope of the purpose. The publications were selected on the basis of the authors’ research of various aspects of identity and the difference in interpreting the phenomenon. Results. Analysis of Scopus publications made it possible to assert that the problem of identity is moving out of the anthropological context and acquiring new technical and technological frameworks (for example, scholars are raising the problem of the digital data identity, digital identification in the context of online transactions). At the same time, the anthropological view of identity remains. It is found for instance in the context of narratives, texts of a person about self that are posted on the Internet. In this context, the concept of “Person Life View” (M. Schechtman) is presented as a variant of a person’s holistic view of the self. The analysis of domestic publications makes it possible to conclude that representatives of social sciences and humanities in their research strive to overcome the dynamic view of a person (dissolving of identity or an absent self), are in search of models of “stability” of identity. Conclusion. Posing the question about the personal identity of a modern person, it seems that the border between the directly human (consciousness and body, for example) and the technical and technological (the Internet and the objective world) is becoming more and more destabilized every day. This predetermines the direction of the research. Contemporary scholars, who publish the results of their work in journals included in scientific databases, are faced not only with the problem of substantiating human identity as a theoretical concept that reflects the modern situation, but also with the problem of finding models in which a person is able to embody the idea of “stability” of identity in the everyday life. (shrink)

Summary Sydney Chapman is unanimously considered to have played a founding role in modern geomagnetism and to have opened up new lines of research in geophysics generally. Nevertheless, Chapman's conviction regarding the synthesis of the explanatory mechanisms of the atmosphere has gone practically unnoticed in the historiography of geophysics. This paper examines Chapman's contribution to ionospheric physics. It aims to understand Chapman's theory of ionospheric layer formation, and particularly its link to his theory of ozone formation. It deals (...) first with the traits which characterized Chapman's personality, as a way of explaining—and even perhaps justifying— his quest for the integration and synthesis of geophysical knowledge. It then analyses Chapman's model of ionospheric layers and his suggestions regarding its use as an operational tool (without ontological connotations), before continuing with his account of the formation of the ozone layer, which seemed to constitute the missing link for understanding ionosphere layer formation. The paper concludes with Chapman's attempt to reconcile geomagnetic and radio evidence. (shrink)

This paper argues that humans possess unique cognitive abilities due to the presence of a functional system that exists in the human brain that is absent in the non-human brain. This system, the frontal feedback system, was born in the hominin brain when the great phylogenetic expansion of the prefrontal cortex relative to posterior sensory regions surpassed a critical threshold. Surpassing that threshold effectively reversed the preferred direction of information flow in the highest association regions of the neocortex, producing the (...) frontal feedback system. This reversal was from the caudo-rostral bias characteristic of non-human, or pre-human, brain dynamics to a rostro-caudal bias characteristic of modern human brain dynamics. The frontal feedback system works through frontal motor routines, or action schemes, manipulating the release and reconstruction of stored sensory memories in posterior sensory areas. As an obligatory feature of frontal feedback, a central character, or self, emerges within this cortical network that manifests itself as agent in these reconstructions as well as in the experience of sensory perceptions. Dynamical-systems modeling of cortical interactions is combined in the paper with recent neuroimaging studies of “resting-state” brain activity to bridge the gap between microscopic and macroscopic levels of cortical behavior. This synthesis is used to support the proposal of an information flow reversal occurring in the hominin brain and also to explain how such a reversal generates the wide variety of cognitive and experiential phenomena that many consider to be uniquely human. (shrink)

Ecology in principle is tied to evolution, since communities and ecosystems result from evolution and ecological conditions determine fitness values. Yet the two disciplines of evolution and ecology were not unified in the twentieth-century. The architects of the Modern Synthesis, and especially Julian Huxley, constantly pushed for such integration, but the major ideas of the Synthesis—namely, the privileged role of selection and the key role of gene frequencies in evolution—did not directly or immediately translate into ecological science. (...) In this paper I consider five stages through which the Synthesis was integrated into ecology and distinguish between various ways in which a possible integration was gained. I start with Elton’s animal ecology, then consider successively Ford’s ecological genetics in the 1940s, the major textbook Principles of animal ecology edited by Allee et al., and the debates over the role of competition in population regulation in the 1950s, ending with Hutchinson’s niche concept and McArthur and Wilson’s Principles of Island Biogeography viewed as a formal transposition of Modern Synthesis explanatory schemes. I will emphasize the key role of founders of the Synthesis at each stage of this very nonlinear history. (shrink)

The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense (Mossio et al., 2009).] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics (via the bridging abstractions of chemistry) and there are many new abstractions from advances in mathematics (incentivized by the need for more capable computational analyses). Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology (ICT) for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 (preamble, introduction, motivation and major biomathematical problems) are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems (GTLS) from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

This editorial introduces a series of review articles concerning the ways in which recent work on microbial evolution has both deepened and challenged the modern synthesis. The authors develop a framework for thinking about theory change in biology.

The Modern Synthesis has been receiving bad press for some time now. Back in 1983, in an article entitled “The Hardening of the Modern Synthesis” Stephen Jay Gould criticized the way the Modern Synthesis had developed since its inception in the 1930s and early 1940s (Gould 1983). Back then, those who would later become known as ‘architects’ of the synthesis were united in their call for explaining evolution at all levels in terms of (...) causation at one level: genetics. What drove changes in gene frequency remained an open question. It could be mainly selection, or drift, or some (other) form of constraint. But in the two decades that followed, the synthesis underwent a major change. By the late 1940s the synthesis had ‘hardened’ around adaptationism, according to Gould. Influential contributors like Dobzhansky, Simpson and Wright had increasingly expressed adaptationist views in the later editions of their landmark books. Not because evidence had piled up, showing that selection was in fact pervasive. Instead, Gould argued, adaptationist tendencies had been preserved by some kind of cultural inertia, and were now being revived. “Certain ‘national styles’ persisted from the eighteenth century, through Darwin’s era, and into our own time. Views on adaptation provide a good example” (Gould 1983). Gould did not just argue that some form of adaptationism had resurfaced. He became well-known for his efforts to intervene on this status quo by attempting to make evolutionary biology more ‘pluralistic’. In collaborative work with Richard Lewontin (Gould and Lewontin 1979), Elisabeth Vrba (Gould and Vrba 1982; Vrba and Gould 1986) and Niles Eldredge (Eldredge and Gould 1972; Gould and Eldredge 1977) he criticized the synthesis for its adaptationism and its lack of appreciation for hierarchical perspectives. Gould exerted his influence in a different way as well. Together with Eldredge, he had facsimiles reprinted of the first editions of two books that had shaped synthesis, but with their own critical introductions (Eldredge 1982; Gould 1982). Dobzhansky’s Genetics and the Origin of Species and Mayr’s Systematics and the Origin of Species appeared as reprints in the ‘Columbia Classics in Evolution’ series, sending an unambiguous message to the readers: these are foundational works, but they have been superseded. In the summer of 2008, some 25 years after Gould made his point about the hardening of the Modern Synthesis, a group of sixteen biologists and philosophers gathered at the Konrad Lorenz Institute for Evolution and Cognition Research (KLI) near Vienna, Austria, to discuss cutting-edge research that reaches beyond the synthesis framework. Before it even started, this workshop on the ‘Extended Synthesis’ had already attracted a fair share of attention in the blogosphere and had resulted in a news feature in Science (Pennisi 2008). After the meeting, Nature weighed in on the matter (Whitfield 2008). The results of over 3 days of presentations and extensive discussion have now been published as Evolution—The Extended Synthesis. 1 The publication of this collection of sixteen essays is accompanied by the republication of Julian Huxley’s Evolution: The Modern Synthesis; the book that introduced the term ‘Modern Synthesis’. Both books are introduced by the organizers of the KLI workshop, Massimo Pigliucci and Gerd Müller. Like Gould and Eldredge before them, Pigliucci and Müller did not reissue one of the canons of the Modern Synthesis without giving the readers some ‘guidance’. Starting with the cover, the editors proclaim boldly that this is ‘the definitive edition’ of Huxley’s book. In a new foreword, they sketch the context in which the book was written and assess some of its features. They voice some mild criticism of alleged ‘adaptationism’. But their tone is different from that of Gould and Eldredge. Pigliucci and Müller praise Huxley for his pluralistic outlook, which has again become essential in the forging of an Extended Synthesis. That makes Huxley’s book more than just an interesting but obsolete classic. Instead, it can teach valuable lessons about how to ‘soften up’ a synthesis that has become hardened over time. (shrink)