In this article we shall attempt to show that despite the originality of Sartre's writings and the original philosophical views they contain, his reliance on Goethe's Faust in The Devil and the Good Lord proves that he was quite familiar with the components of the former and made intensive use of them in his own play. A comparative analysis of the two texts will show that Sartre exploited any ethical problem, human act, historical name and fact which he was able (...) to fit into his own philosophical and social positions and which could contribute to his dramatic art. (shrink)

Research ethics review is a critical aspect of the research governance framework for human subjects research. This usually requires that research protocols be submitted to a research ethics committee for review and approval. This has led to very rapid developments in the domain of research ethics, as RECs proliferate all over the globe in rhyme with the explosion in human subjects research. The work of RECs has increasingly become elaborate, complex, and in many cases urgent, necessitating supporting rules and procedures (...) of operation. Guidelines for elaborating standard operating procedures for the functioning of RECs have also been proposed. The SOPs of well-placed and well-resourced RECs have tended to pay much attention to details, resulting, as a consequence, in generally long, elaborate, intricate and complex SOPs; a model that can hardly be replicated by other committees, equally under ethics review pressures, but working under much more constraining conditions in resource-destitute environments. In this paper, we looked at the content and length of SOPs from African RECs and compared them to the World Health Organization ’s guidelines as the gold standard. We also looked at the SOPs from the Ethics Review and Consultancy Committee of the Cameroon Bioethics Initiative that we elaborated in a simplified way in 2013, and compared them to the WHO’s guidelines and to the other SOPs. Sixteen SOPs from 14 African countries were collected from various sources. Their average length was of 30 pages. By comparison to the guidance of the WHO, only six of them were found acceptable with more than 70 % of the criteria from the gold standard that were fully described. Among those six, two of them were very long and detailed, while the four remaining SOPs ranged from 16 to 24 pages. The ERCC SOPs are seven pages long but maintain all that is of essence for the rigorous, efficient and timely review of protocols. We are convinced that, because of their brevity, simplicity, clarity and user-friendliness, the ERCC SOPs recommend themselves as a model template to, at least, committees similarly situated and/or circumstanced as the ERCC of the Cameroon Bioethics Initiative is. In fact, brevity, clarity, simplicity and user-friendliness are recognized values. Whatever is brief and clear is better than what is not and saves time. What is simple and user-friendly is better than what is not even though the two have the same aims because it saves both time and mental energy. And if this be true in general, it is even truer of the context and its peculiar constraints that we are addressing. (shrink)

The introduction of genomics and biobanking methodologies to the African research context has also introduced novel ways of doing science, based on values of sharing and reuse of data and samples. This shift raises ethical challenges that need to be considered when research is reviewed by ethics committees, relating for instance to broad consent, the feedback of individual genetic findings, and regulation of secondary sample access and use. Yet existing ethics guidelines and regulations in Africa do not successfully regulate research (...) based on sharing, causing confusion about what is allowed, where and when. In order to understand better the ethics regulatory landscape around genomic research and biobanking, we conducted a comprehensive analysis of existing ethics guidelines, policies and other similar sources. We sourced 30 ethics regulatory documents from 22 African countries. We used software that assists with qualitative data analysis to conduct a thematic analysis of these documents. Surprisingly considering how contentious broad consent is in Africa, we found that most countries allow the use of this consent model, with its use banned in only three of the countries we investigated. In a likely response to fears about exploitation, the export of samples outside of the continent is strictly regulated, sometimes in conjunction with regulations around international collaboration. We also found that whilst an essential and critical component of ensuring ethical best practice in genomics research relates to the governance framework that accompanies sample and data sharing, this was most sparingly covered in the guidelines. There is a need for ethics guidelines in African countries to be adapted to the changing science policy landscape, which increasingly supports principles of openness, storage, sharing and secondary use. Current guidelines are not pertinent to the ethical challenges that such a new orientation raises, and therefore fail to provide accurate guidance to ethics committees and researchers. (shrink)

Background The rise in genomic and biobanking research worldwide has led to the development of different informed consent models for use in such research. This study analyses consent documents used by investigators in the H3Africa (Human Heredity and Health in Africa) Consortium. Methods A qualitative method for text analysis was used to analyse consent documents used in the collection of samples and data in H3Africa projects. Thematic domains included type of consent model, explanations of genetics/genomics, data sharing and feedback of (...) test results. Results Informed consent documents for 13 of the 19 H3Africa projects were analysed. Seven projects used broad consent, five projects used tiered consent and one used specific consent. Genetics was mostly explained in terms of inherited characteristics, heredity and health, genes and disease causation, or disease susceptibility. Only one project made provisions for the feedback of individual genetic results. Conclusion H3Africa research makes use of three consent models—specific, tiered and broad consent. We outlined different strategies used by H3Africa investigators to explain concepts in genomics to potential research participants. To further ensure that the decision to participate in genomic research is informed and meaningful, we recommend that innovative approaches to the informed consent process be developed, preferably in consultation with research participants, research ethics committees and researchers in Africa. (shrink)

Many ethical concerns surrounding human genetics studies remain unresolved. We report here the situation in Cameroon.Objectives: To describe the profile of human genetic studies that used Cameroonian DNA samples, with specific focus on i) the research centres that were involved, ii) authorship, iii) population studied, iv) research topics and v) ethics disclosure, with the aim of raising ethical issues that emerged from these studies.Method: Bibliometric Studies; we conducted a PubMed-based systematic review of all the studies on human genetics that used (...) Cameroonian DNA samples from 1989 to 2009.Results and Discussion: Fifty articles were identified, involving predominantly research centres from Europe (64%) and America (32%). Only 7 (14%) Cameroonian institutions and 14 (28%) Cameroonian authors were associated with these publications.At least 52% of publications were devoted to population genetics (variation/migration patterns) amongst 30 Cameroonian ethnic groups. Very few studies concerned public health related genetic issues and only 5 (10%) references were found for hemoglobinopathies like sickle cell anaemia. Almost all DNA samples are ‘banked’ outside of the African continent.Capacity building, rights to the genetic information and benefits to the individuals, communities and populations who contribute to these studies are addressed.Conclusions: 1) Our data suggests the need for a wider debate towards building capacity and addressing ethical issues related to human genomic research in sub-Saharan Africa and specifically in Cameroon; 2) National ethical guidelines and regulations concerning the collection, use and storage of human DNA are urgently needed in Cameroon. (shrink)

Although the world has experienced remarkable progress in health care since the last half of the 20th century, global health inequalities still persist. In some poor countries life expectancy is between 37-40 years lower than in rich countries; furthermore, maternal and infant mortality is high and there is lack of access to basic preventive and life-saving medicines, as well a high prevalence of neglected diseases, HIV/AIDS, tuberculosis, and malaria. Moreover, globalization has made the world more connected than before such that (...) health challenges today are no longer limited within national or regional boundaries, making all persons equally vulnerable. Because of this, diseases in the most affluent countries are closely connected with diseases in the poorest countries. In this paper, we argue that, because of global health inequalities, in a situation of equal vulnerability, there is need for global solidarity not only as a means of reducing health inequalities, but also as a way of putting up a united force against global health challenges. We argue for an African approach to solidarity in which the humanity of a person is not determined by his/her being human or rational capacity, but by his/her capacity to live a virtuous life. According to this view of solidarity, because no one is self-sufficient, no individual can survive alone. If we are to collectively flourish in a world where no individual, nation or region has all the health resources or protection needed for survival, we must engage in solidarity where we remain compassionate and available to one another at all times. (shrink)

Background Universities in Cameroon are playing an active part in HIV/AIDS research and much of this research is carried out by students, usually for the purpose of a dissertation/thesis. Student theses/dissertations present research findings in a much more comprehensive manner and have been described as the stepping-stone of a budding scientist’s potential in becoming an independent researcher. It is therefore important to verify how students handle issues of research ethics. Method Theses/dissertations on HIV/AIDS that described research studies involving the use (...) of human research participants were screened to verify if research ethics approval and informed consent were obtained and documented. The contents of the consent forms were also qualitatively analyzed. Results Of 174 theses/dissertations on HIV, ethics approval was documented in 17 and informed consent in 77. Research ethics approval was first mentioned at all in 2002 and highly reported in the year 2007. Evidence of ethics approval was found for the first time in 2005 and informed consent first observed and evidenced in 1997. Ethics approval was mostly reported by students studying for an MD and was not reported in any Bachelors’ degree dissertation. Informed consent was also highly reported in MD theses followed by undergraduate theses. Voluntary participation and potential benefits of the study were some of the common aspects dealt with in most of the consent forms. The right to discontinue participation in the study and management of residual samples were scarcely ever mentioned. Conclusions Overall, and given the current state of the art of research ethics around the world, student-scientists in Cameroon would seem to be merely kidding with research ethics. It is thus essential that training in health research ethics be incorporated in the curriculum of universities in Cameroon in order that the next generation of scientists may be better equipped with thorough knowledge and practice of HRE. This, we believe, would be one way of fighting the occurrence of research scandals, which have not yet abated significantly, especially those arising from negligence or inexcusable ignorance. (shrink)

"To some people, life is very simple . . . no shadings and grays, all blacks and whites. . . . Now, others of us find that good, bad, right, wrong, are many-sided, complex things. We try to see every side; but the more we see, the less sure we are." —Sir John Talbot, The Wolf Man (Universal Pictures, 1941).

"To some people, life is very simple . . . no shadings and grays, all blacks and whites. . . . Now, others of us find that good, bad, right, wrong, are many-sided, complex things. We try to see every side; but the more we see, the less sure we are.".

Universiteiten hebben tegenwoordig een missie. Die missie verwoorden zij in hun strategische plannen en hun jaarverslagen. Tot de missie van de universiteit waarvoor ik werk, de Rijksuniversiteit Groningen, behoort nadrukkelijk dat zij de publieke rol en relevantie van de wetenschap en van de wetenschappers die haar beoefenen wil bevorderen. Daarmee bevestigt de universiteit een lange traditie waarin van wetenschappers als vanzelfsprekend wordt verwacht dat zij naast het geven van wetenschappelijk onderwijs en het verrichten van wetenschappelijk onderzoek tevens een intellectuele taak (...) hebben. Die taak delen zij met andere professionals, van kunstenaars tot journalisten, schrijvers en essayisten. Een intellectueel is iemand die zijn kennis of professionele vaardigheden op actieve wijze inzet ten bate van het algemeen belang, of beter: van de publieke zaak. Ik kom nog terug op intellectuelen en hun publieke rol. Hier gaat het me om die missie. (shrink)

Exhibition catalogue for the exhibition of drawings and paintings held as part of the Wilderness and Inner Space conference at the University of Kent, Canterbury 2008. The concept of Territorialization from Deleuze and Guattari is linked to ideas of wilderness to both describe the psychotherapeutic relationship and to critique the proposed state regulation of the psychotherapies. The transference and counter transference relation between client and psychotherapist is described as a process of territorialization and deterritorialization in which a dream of the (...) client led to the production of art works by the psychotherapist. This at work led to the production of imagery based around the therapeutic relationship involving key images of wild animals. The animal imagery is linked to Deleuze and Guattari's re-interpretation of Freud’s interpretation of the Wolfman dream, emphasizing the social and historical determinants of dream imagery. The interrelationships between Wilderness, Territorialization and the personal and the political in dream imagery suggest the psychotherapeutic space as located on the borders between the social and a wild or wilderness space. The need to recognise the wild dimension of psychotherapy highlights the necessity to resist the imposition of monocultures of therapeutic practice through possible state regulation. (shrink)

Women in Rock, Women in Romanticism is the first book-length work to explore the interrelationships between contemporary female musicians and eighteenth- and nineteenth-century art, music, and literature by women and men. The music and videos of contemporary musicians including Erykah Badu, Beyoncé, The Carters, Hélène Cixous, Missy Elliot, the Indigo Girls, Janet Jackson, Janis Joplin (and Big Brother and the Holding Company), Natalie Merchant, Joni Mitchell, Janelle Monáe, Alanis Morrisette, Siouxsie Sioux, Patti Smith, St. Vincent (Annie Clark), and Alice (...) Walker are explored through the lenses of pastoral and Afropresentism, Gothic, female Gothic, and the literature of William Blake, Beethoven, Arthur Schopenhauer, Samuel Taylor Coleridge, Charlotte Dacre, Ralph Waldo Emerson, E.T.A. Hoffmann, Ann Radcliffe, William Shakespeare, Mary Shelley, her husband Percy Shelley, Henry David Thoreau, Horace Walpole, Jane Williams, Mary Wollstonecraft, and William Wordsworth to explore how each sheds light on the other, and how women have appropriated, responded to, and been inspired by the work of authors from previous centuries. (shrink)

Balanceren. Dat is waar sociale ondernemers onderlegd moeten in zijn: balanceren tussen sociale en economische doelstellingen, tussen empathie en zakelijkheid, tussen bedrijfsstabiliteit en sociale meerwaarde, tussen flexibiliteit en rigiditeit, tussen idealisme en realiteitszin. Sociaal ondernemen is dan ook een complexe uitdaging. Dat mag alvast een conclusie zijn van dit boek en het onderzoek waarop het gebaseerd is. Een andere vaststelling is dat sociale ondernemers, ook in moeilijke omstandigheden, bijzonder gedreven blijven om hun sociale missie waar te maken.0Er bestaat onmiskenbaar een (...) groeiende interesse in sociale en maatschappelijk verantwoorde bedrijfsvoering, die zich vertaalt in aandacht voor het welzijn en de ontwikkeling van de medewerkers, milieubewustzijn, duurzame productieketens, en dergelijke. Dit boek tracht inzicht te geven in welke vlag de lading ‘sociaal ondernemerschap’ dekt, zonder in zwart-witdenken te vervallen.0Het boek bouwt voort op wetenschappelijk onderzoek van de Hogeschool Gent, een samenwerkingsproject tussen de Faculteit Bedrijf & Organisatie en de onderzoeksgroep Sociale innovatie en Ondernemerschap van de Geassocieerde Faculteit Handelswetenschappen en Bestuurskunde. (shrink)

When thinking about Frank M. Oppenheim’s legacy, one cannot help but think, first and foremost, about his many contributions to Royce scholarship. Yet I personally have had some difficulty imagining how to characterize Oppenheim’s contributions to Royce scholarship until late 2013. Prior to that time, the more I thought about how to characterize his contributions to Royce scholarship, the less I became able to imagine an appropriate characterization of them. Then, on an autumn afternoon in 2013, I stumbled across a (...) Tumblr post, written by Missy H. Dunaway, that caught my attention. The title of that post was “‘The Lonely’ Lighthouse Keeper.” Dunaway’s post was an entertaining yet sad account of her fascination with... (shrink)

"Your confidentiality will be respected. Information that discloses your identity will not be released without your consent unless required by law or regulation." I sat there with Missy, reading the consent form line by line. When I got to the section on confidentiality, I told her she could pick a nickname, or fake name, that I would use in my research notes and later when the research was written up. She wanted to use "Missy." It wasn't exactly a (...) pseudonym—this was the same name that a number of her friends in the neighborhood knew her by. I'd also heard a couple of nurses calling her Missy when I had gone to visit with her in the hospital earlier that winter. I asked her if she was sure she wanted to use that .. (shrink)