The framework proposed by Dupras and Bunnik was developed in response to their recognition that standard regulations are increasingly inadequate to address the complex privacy issues created by the...

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

The generalizability crisis is compounded, or even partially caused, by a lack of specificity in psychological theories. Expanding the use of mechanistic models among psychologists is therefore important, but faces numerous hurdles. A cultural evolutionary approach can help guide and evaluate interventions to improve modeling efforts in psychology, such as developing standards and implementing them at the institutional level.

This article reflects on the relative silence of African farmers within debates around the potential for genetically modified crops to transform agriculture on the continent. It proposes two strategies for amplifying these voices—one focused on research methodologies, the other on outreach—in order to transform the conversation around GM’s potential in Africa into one that revolves around farmer preferences and priorities.

AbstractIntegrity is considered an important corporate value. Yet recent global events have highlighted the challenges firms face at living up to their stated values, especially when extended supply chain partners are involved. The concept of Supply Chain Integrity (SCI) can help firms shift focus beyond internal corporate integrity, toward supply chain integrity. Researchers and managers will benefit from an understanding of the SCI concept toward implementing SCI to better align supply chain partners with stated corporate values. This research fully develops (...) and empirically grounds the firm-level, inter-firm-oriented SCI concept. The thematic analysis of six firms’ archival and website content elaborated empirical descriptions of SCI themes and enabled the development of a process model for SCI, presenting a novel view of the underlying process by which firms can assess, develop, and maintain SCI across their supply chains. We propose the SCI model as an evolutionary process to improve a firm’s supply chain sustainability, rather than a dichotomous end state where firms either “have” integrity or they don’t. The SCI model could be used as a tool to help leaders create necessary change to better align values and supporting statements with culture, while influencing and affecting stakeholders across the supply chain. This is particularly important in today’s world, where business leaders must consider all stakeholders and address important stakeholder-driven issues such as supply chain sustainability, resilience, and security, which are now at the forefront in the ever-changing environment. (shrink)

In the covariant Hamiltonian mechanics with action-at-a-distance, we compare the proper time and dynamical time representations of the coordinate space world line using the differential geometry of nongeodesic curves in 3+1 Minkowski spacetime. The covariant generalization of the Serret-Frenet equations for the point particle with interaction are derived using the arc length representation. A set of invariant point particle kinematical properties are derived which are equivalent to the solutions of the equations of motion in coordinate space and which are functions (...) of either the proper time or the dynamical time. Expressions for the quantities are given for the example of the covariant harmonic oscillator and comments are offered regarding the measurability of the dynamical time. (shrink)

The extended Church-Turing thesis posits that any computable function can be calculated efficiently by a probabilistic Turing machine. If this thesis held true, the global effort to build quantum computers might ultimately be unnecessary. The thesis would however be strongly contradicted by a physical device that efficiently performs a task believed to be intractable for classical computers. BosonSampling - the sampling from a distribution of n photons undergoing some linear-optical process - is a recently developed, and experimentally accessible example of (...) such a task [1]. (shrink)

We consider a quaternionic quantum formalism for the description of quantum states and quantum dynamics. We prove that generalized quantum measurements on physical systems in quaternionic quantum theory can be simulated by usual quantum measurements with positive operator valued measures on complex Hilbert spaces. Furthermore, we prove that quaternionic quantum channels can be simulated by completely positive trace preserving maps on complex matrices. These novel results map all quaternionic quantum processes to algorithms in usual quantum information theory.

Epistemological questions about the significance of disagreement have advanced in concert with broader developments in social epistemology concerning testimony, the nature of expertise and epistemic authority, the role of institutions, group belief, and epistemic injustice (among others). During this period, related issues in the epistemology of religion have reemerged as worthy of new consideration, and available to be situated with new conceptual tools. This volume explores many of the issues at the intersection of the epistemology of disagreement and religious epistemology: (...) in particular, how to think carefully about religious diversity and disagreement, balancing epistemic humility with personal conviction, the place of religious belief in our social lives, and how best to think about truths concerning religion. (shrink)

Written exclusively in the third-person by a narrator who repeatedly refers to “Henry Adams” as “passive,” “submissive,” and “a helpless victim” in relation to the “forces” in the world that form him, The Education of Henry Adams attenuates both author and subject by valuing environment over eponym. The critical literature on the text has focused primarily on the formal or psychological bases of such practice in order to argue that Adams is behind, and thus exempt from, the book's paradoxical self-effacements. (...) But for Adams the rationale for the impersonal, evacuated form of The Education is more ontological than personal, the necessary consequence of his quietistic belief in a materialist determinism so absolute as to reduce persons and history alike to “sum[s].... of the forces” of “nature.” This belief, one shared by many of his contemporaries and most fully evolved in Adams's “dynamic theory of history,” entails, in the context of The Education, making the distinction between auto-biography and autobiography, between a text generated by an “automaton” and one written by a person. Routed through a discussion of de Man's and Kierkegaard's conceptions of irony, this essay explores the relevance of such a distinction to both the humanism of Adams's age and the posthumanism of our own. (shrink)

A great deal of ink has been spilt debating the relative merits of foundationalism and coherentism in contemporary epistemology. In this dissertation, I argue that the debate itself, lively as it's been, rides atop a fundamental mistake. Careful examination of the defenses of these views indicates that both sides rest on a set of problematic presuppositions about justification and the nature of mind. More specifically, they all assume, in one form or another, that epistemic dependence must be inferential, and, as (...) a result, that direct access to the world could only be understood as resting on a class of entities which asymmetrically convey justification to other beliefs without receiving support from them. Revealing these assumptions promises to show that there is a much larger range of options for explaining our knowledge of the world than we can see when we are in the grips of an approach to epistemology and the philosophy of mind which requires us to choose between foundationalism and coherentism. (shrink)

I explicate and defend Kant's analysis of “skepticism” as a single, metaphilosophically unified rational phenomenon (at A756–764/B784–797, for instance). Kant anticipates one of the defining trends of contemporary epistemology's approach to radical philosophical skepticism: the thought that skepticism cannot be directly refuted, by demonstrating its falsity, but must be diagnosed, to show that its premises are unnatural, and consequently fail to be rationally compelling from within our own nonskeptical standpoint. Kant's most ambitious claim here is that he will develop this (...) diagnosis in a unitary fashion, by demonstrating that Cartesian, Humean, Pyrrhonian, and Agrippan skepticism are essentially interrelated as so many means to “the skeptic's” defining philosophical end. This “unity thesis” comes in both weak and strong variations. First, and more weakly, Kant argues that apparently distinct skeptical problematics share certain crucial metaphilosophical assumptions about the nature of reason, and the role of philosophical self-knowledge. More strongly, he also claims that the four problematics just mentioned are related hierarchically, in that the more fundamental skeptical worries constitute the essential dialectical context for the less fundamental ones, such that the more superficial problematics only arise if a logically prior worry is first acceded to. By showing how deeply these two unity theses structure Kant's Critical methodology, I argue that the Kantian view of philosophy as a “doctrine of wisdom” incorporates, and arguably surpasses, a number of key insights found in more recent work. The final result is that the transcendental philosopher may hope to co-opt the attractions of skepticism without making any unnecessary concessions along the way. (shrink)

For many decades, researchers have explored the true potential of human achievement. The expertise field has come a long way since the early works of de Groot (1965) and Chase and Simon (1973). Since then, this inquiry has expanded into the areas of music, science, technology, sport, academia and art. Despite the vast amount of research to date, the capability of study methodologies to truly capture the nature of expertise remains questionable. Some considerations include (i) the individual bias in the (...) retrospective recall of developmental activities, (ii) the ability to develop ecologically valid tasks, and (iii) difficulties capturing the influence of confounding factors on expertise. This article proposes that expertise research in electronic sports (esports) presents an opportunity to overcome some of these considerations. Esports involves individuals or teams of players that compete in video game competitions via human-computer interaction. Advantages of applying the expert performance approach in esports include (i) developmental activities are objectively tracked and automatically logged online, (ii) the constraints of representative tasks correspond with the real-world environment of esports performance, and (iii) expertise has emerged without the influence of guided systematic training environments. Therefore, this article argues that esports research provides an ideal opportunity to further advance research on the development and assessment of human expertise. (shrink)

Resources the virtue of humility as an essential divine attribute through the works of Augustine, Barth, and Katherine Sonderegger.

During the Nazi era, physicians provided expertise and a veneer of legitimacy enabling crimes against humanity. In a creative educational initiative to address current ethical dilemmas in clinical medicine, we conduct ethics learning missions bringing senior physicians to relevant Nazi era sites in either Germany or Poland. The tours share a core curriculum contextualising history and medical ethics, with variations in emphasis. Tours to Germany provide an understanding of the theoretical origins of the ethical violations and crimes of Nazi physicians. (...) Tours to Poland address the magnitude of the Nazi physician’s atrocities as well as displays of heroism by Jewish and righteous among the nations' physicians. Exemplary as well as shameful physician behaviour is analysed from an ethical perspective. A combination of unique educational methodologies maximises learning and personal growth, enabling participants to examine ethically complex clinical situations with extrapolation to modern-day medical practice. Learning is designed with relevance to contemporary medical ethics dilemmas such as beginning and end-of-life issues, providing tenets from which participants can develop as more ethical and informed physicians. Participant feedback confirms efficacy and worth of these growth-promoting ethics learning tours which should be expanded to other international groups and settings. (shrink)

Since the 1980s, the mass media have changed the way they cover major political stories, like foreign policy crises. As a consequence, what the public learns about these events has changed. More media outlets cover major events than in the past, including the entertainment-oriented soft news media. When they do cover a political story, soft news outlets focus more on than traditional news media and less on the political or strategic context, or substantive nuances, of policy debates. Many Americans who (...) previously ignored most political news now attend to some information about major political events, like wars, via the soft news media. These changes have important implications for democratic politics. Most importantly, a large number of particularly persuadable potential voters are now tuning in to politics via soft news outlets. This gives politicians an incentive to develop strategies for reaching out to them. Such individuals care less about the nuances of policy and more about the personality of leaders and any sensational human drama that a policy, like a war, entails. Soft news consumers care less about geopolitics than about body bags. Politicians who want their votes are therefore likely to emphasize body bags more than geopolitics. In short, the media environment changes both the style and substance of politics in democracies. (shrink)

In examining Randy Cohen, an ethical advice giver for The New York Times Magazine, this article traces out special concerns of “applied philosophers” including: dissemination of ideas through a media, disparity of public understanding of philosophical (particularly ethical) issues and the contributions to these issues by specific people, and, of course, money. It skips the question of whether or not what Cohen does is philosophy in favor of examining how whatever he does is like the philosophy that philosophers often claim (...) to be doing. Cohen, then, is a doppelganger for philosophers, particularly those working in applied philosophy, that needs to be considered. The way he wades through a big-business format to discuss individual concerns may provide a model (even if it is of what not to do) for philosophers looking to actually affect change with their ethical pronouncements. (shrink)

What is it to know someone? Epistemologists rarely take up this question, though recent developments make such inquiry possible and desirable. This paper advances an account of how such interpersonal knowledge goes beyond mere propositional and qualitative knowledge about someone, giving a central place to second-personal treatment. It examines what such knowledge requires, and what makes it distinctive within epistemology as well as socially. It assesses its theoretic value for several issues in moral psychology, epistemic injustice, and philosophy of mind. (...) And it offers an account of the complex content in play if interpersonal knowledge is to be understood in terms of its mental states and their functions. (shrink)

Juslin & Vll's (J&V's) discussions of evaluative conditioning and episodic memory focus on circumstances in which music becomes associated with arbitrary life events. However, analyses of film music suggest that viewers experience consistent pairings between types of music and types of narrative content. Researchers have demonstrated that the emotional content of film music has a major impact on viewers' emotional experiences of a narrative.

The Knowledge Norm or Knowledge Account of Assertion (KAA) has received added support recently from data on prompting assertion (Turri 2010) and from a refinement suggesting that assertions ought to express knowledge (Turri 2011). This paper adds another argument from parenthetical positioning, and then argues that KAA’s unified explanation of some of the earliest data (from Moorean conjunctions) adduced in its favor recommends KAA over its rivals.

Artificial moral agents raise complex ethical questions both in terms of the potential decisions they may make as well as the inputs that create their cognitive architecture. There are multiple differences between human and artificial cognition which create potential barriers for artificial moral agency, at least as understood anthropocentrically and it is unclear that artificial moral agents should emulate human cognition and decision-making. It is conceptually possible for artificial moral agency to emerge that reflects alternative ethical methodologies without creating ontological (...) challenges or existential crises for human moral agents. (shrink)

Previous work on the comprehension of agreement has shown that incorrectly inflected verbs do not trigger responses typically seen with fully ungrammatical verbs when the preceding sentential context furnishes a possibly matching distractor noun (i.e., agreement attraction). We report eight studies, three being direct replications, designed to assess the degree of similarity of these errors in the comprehension of subject-verb agreement along the dimensions of grammatical gender and number in Modern Standard Arabic. A meta-analysis of the results demonstrate the presence (...) of agreement attraction effects in reading comprehension for gender and number on verbs. Moreover, the meta-analysis demonstrates that these two features do not behave identically: gender effects are larger and occur later relative to number attraction effects. These results challenge models of agreement that predict agreement features to be equipotent and show that real-time models of agreement require modifications in the form of cue-weighting in order to account for these differential results. (shrink)

Assertion is governed by an epistemic norm requiring knowledge. This idea has been hotly debated in recent years, garnering attention in epistemology, philosophy of language, and linguistics. This chapter presents and extends the main arguments in favor of the knowledge norm, from faulty conjunctions, several conversational patterns, judgments of permission, excuse, and blame, and from showing how. (Paired with a chapter by Peter J. Graham and Nikolaj J. L. L. Pedersen, "Knowledge is Not Our Norm of Assertion.").

John N. Williams (1994) and Matthew Weiner (2005) invoke predictions in order to undermine the normative relevance of knowledge for assertions; in particular, Weiner argues, predictions are important counterexamples to the Knowledge Account of Assertion (KAA). I argue here that they are not true counterexamples at all, a point that can be agreed upon even by those who reject KAA.

Some philosophers oppose recent arguments for the Knowledge Norm of Assertion by claiming that assertion, being an act much like any other, will be subject to norms governing acts generally, such as those articulated by Grice for the purpose of successful, cooperative endeavours. But in fact, Grice is a traitor to their cause; or rather, they are his dissenters, not his disciples. Drawing on Grice's unpublished papers, I show that he thought of asserting as a special linguistic act in need (...) of its own norm, and he tied his maxim of Quality to knowledge. I also develop a simple Gricean-inspired argument showing that the Quality maxim is not dependent on the Cooperative Principle. If it is not thus dependent, then the Cooperative Principle cannot be the explanation of, or source of normativity for, the Quality maxim. Thus, leveraging the insights informing the maxim of Quality actually provides the resources for a distinctive positive case that knowledge is the constitutive norm of assertion. (shrink)

Locke’s commentators are divided about whether Locke thinks that the idea of a person is a substance-idea or a mode-idea. I use Locke’s theory of kinds to argue for an intermediate interpretation on which the idea of a person is a substance-idea that contains a mode-idea. As a result, while proponents of the substance interpretation correctly claim that ‘person’ designates a kind of substance, proponents of the mode interpretation are nonetheless correct in insisting that mode-ideas play an important role in (...) Locke’s account of persons and personal identity. (shrink)

In the past, Wonder Woman and Superman were depicted as good friends, but as of 2016, in New 52 Wonder Woman comic books, the Amazon princess and the man of steel are in a romantic relationship. The implication seems to be that romantically compatible people cannot be just friends. Thankfully, philosophy can help to debunk this notion and shed some light on the nature of friendship and romance as well. In consuming works of popular culture, people learn what is expected (...) of them in their interpersonal lives: cross‐gender relationships must be romantic, and friendship cannot be as important as romance. The loss of Wonder Woman and Superman as an example of a stable non‐romantic cross‐gender friendship therefore represents not just a change in the treatment of the characters, but a loss of support for the idea that such friendships are possible. (shrink)

In this paper we establish the - and -transfer principles for finitely decidable locally finite varieties, where a class of structures is finitely decidable if the first order theory of its finite members is recursive. The transfer principles deal with the local structure of finite algebras and have strong global consequences.

ABSTRACT In this paper we report the development of a scale measuring Christian ethical beliefs. Three studies refined the Christian Ethical Beliefs Scale from 63 expert-generated potential items. Studies 1 and 3 sampled undergraduate students at private, Christian colleges, and Study 2 utilized a diverse, online sample. Participants responded to an electronic survey of Likert scale items and demographic questions. Following careful assessment of reliability and validity, we present a 20-item scale divided across five factors: Divine Moral Authority, Privacy of (...) Faith, Moral Individualism, Cognition Essential to Personhood, and Value of all Human Beings. This brief scale offers a new way to measure ethical beliefs in religious or nonreligious populations. (shrink)

Encyclopedia entry covering the growing literature on the Knowledge Norm of Assertion (and its rivals), the Knowledge Norm of Action (and pragmatic encroachment), the Knowledge Norm of Belief, and the Knowledge Norm of Disagreement.

Surprisingly little has been written about hedged assertion. Linguists often focus on semantic or syntactic theorizing about, for example, grammatical evidentials or epistemic modals, but pay far less attention to what hedging does at the level of action. By contrast, philosophers have focused extensively on normative issues regarding what epistemic position is required for proper assertion, yet they have almost exclusively considered unqualified declaratives. This essay considers the linguistic and normative issues side-by-side. We aim to bring some order and clarity (...) to thinking about hedging, so as to illuminate aspects of interest to both linguists and philosophers. In particular, we consider three broad questions. 1) The structural question: when one hedges, what is the speaker’s commitment weakened from? 2) The functional question: what is the best way to understand how a hedge weakens? And 3) the taxonomic question: are hedged assertions genuine assertions, another speech act, or what? (shrink)

The problem of evil is the most prominent argument against the existence of God. Skeptical theists contend that it is not a good argument. Their reasons for this contention vary widely, involving such notions as CORNEA, epistemic appearances, 'gratuitous' evils, 'levering' evidence, and the representativeness of goods. We aim to dispel some confusions about these notions, in particular by clarifying their roles within a probabilistic epistemology. In addition, we develop new responses to the problem of evil from both the phenomenal (...) conception of evidence and the knowledge-first view of evidence. (shrink)

Hope, in its propositional construction "I hope that p," is compatible with a stated chance for the speaker that not-p. On fallibilist construals of knowledge, knowledge is compatible with a chance of being wrong, such that one can know that p even though there is an epistemic chance for one that not-p. But self-ascriptions of propositional hope that p seem to be incompatible, in some sense, with self-ascriptions of knowing whether p. Data from conjoining hope self-ascription with outright assertions, with (...) first- and third-person knowledge ascriptions, and with factive predicates suggest a problem: when combined with a plausible principle on the rationality of hope, they suggest that fallibilism is false. By contrast, the infallibilist about knowledge can straightforwardly explain why knowledge would be incompatible with hope, and can offer a simple and unified explanation of all the linguistic data introduced here. This suggests that fallibilists bear an explanatory burden which has been hitherto overlooked. (shrink)

Recent epistemology has focused almost exclusively on propositional knowledge. This paper considers an underexplored area of epistemology, namely knowledge of persons: if propositional knowledge is a state of mind, consisting in a subject's attitude to a (true) proposition, the account developed here thinks of interpersonal knowledge as a state of minds, involving a subject's attitude to another (existing) subject. This kind of knowledge is distinct from propositional knowledge, but it exhibits a gradability characteristic of context-sensitivity, and admits of shifty thresholds. (...) It is supported by a wide range of unexplored linguistic data and intuitive cases; and it promises to illuminate debates within epistemology, philosophy of religion, and ethics. (shrink)

During the nineteenth and early twentieth centuries, a wide variety of American writers proposed the existence of energies connecting human beings to cosmic processes. From varying points of view--scientific, philosophical, religious, and literary--they suggested that such energies would eventually result in the perfection of individual and collective bodies, assuming that assimilation into larger networks of being meant the expansion of humanity's powers and potentialities--a belief that continues to inform much posthumanist theory today. Universes without Us explores a lesser-known countertradition in (...) American literature. As Matthew A. Taylor's incisive readings reveal, the heterodox cosmologies of Edgar Allan Poe, Henry Adams, Charles Chesnutt, and Zora Neale Hurston reject the anthropocentric fantasy that sees the universe as a kind of reservoir of self-realization. For these authors, the world can be made neither "other" nor "mirror." Instead, humans are enmeshed with "alien" processes that are both constitutive and destructive of "us." By envisioning universes no longer our own, these cosmologies picture a form of interconnectedness that denies any human ability to master it. Universes without Us demonstrates how the questions, possibilities, and dangers raised by the posthuman appeared nearly two centuries ago. Taylor finds in these works an untimely engagement with posthumanism, particularly in their imagining of universes in which humans are only one category of heterogeneous thing in a vast array of species, objects, and forces. He shows how posthumanist theory can illuminate American literary texts and how those texts might, in turn, prompt a reassessment of posthumanist theory. By understanding the posthuman as a materialist cosmology rather than a technological innovation, Taylor extends the range of thinkers who can be included in contemporary conversations about the posthuman. (shrink)