The case study presented by Winch and Sinnott (2011) shows not only how difficult it is for clinicians and researchers to identify conflicts of interest (COI), but also how damaging it can be when there are unin- formed and uncoordinated policy responses by senior administrators.

Launched in 2007, the American Medical Students Association PharmFree Scorecard is an annual ranking of conflict of interest policies at American medical centres; it focuses on COIs that may occur when medical education seems likely to be influenced by university-industry relationships, especially those with the pharmaceutical and medical device industries. The PharmFree Scorecard has proven influential in stimulating changes in policy regarding the management of COI at American medical institutions, thus it provides a useful jumping off point for reflection on (...) how and why medical education institutions in other countries – and for our purposes, Canada – should pay more attention to the appropriate identification and management of COI. The PharmFree Scorecard methodology examines a diversity of factors and interests that could influence medical education; as such, it is an interesting approach to analysing the COI policies of medical schools. To test its utility or applicability outside the US, we decided to apply the PharmFree Scorecard to the COI policies of the 16 Canadian universities hosting medical schools. Overall, Canadian institutions rank very poorly, especially in ensuring that education and training tools are provided to staff, students and faculty members to enable the identification and management of COI. However, differences between the US and Canadian medical education contexts, e.g., with regards to the governance and funding of universities, limit to some extent the direct applicability of the AMSA ranking. Canadian medical schools – and their host universities – nonetheless have much to learn from insights provided by the AMSA PharmFree Scorecard ranking, although they can and should go further in developing their own COI policies and procedures. (shrink)

Research on research ethics—regarding both the governance and practice of the ethical review of human subjects research—has a tumultuous history in North America and Europe. Much of the academic literature focuses on issues to do with regulating the conduct and quality of ethics review of research protocols by ethics committees (research ethics boards (REBs) in Canada and institutional review boards (IRBs) in the United States). In addition, some of the literature attends to issues particular to the review of qualitative research, (...) and still other literature addresses the challenges posed by and the need for research on REBs/IRBs. It is this third group of literature within which our article is situated. (shrink)

Background Next Generation Sequencing (NGS) is expected to help find the elusive, causative genetic defects associated with Bipolar Disorder (BD). This article identifies the importance of NGS and further analyses the social and ethical implications of this approach when used in research projects studying BD, as well as other psychiatric ailments, with a view to ensuring the protection of research participants. Methods We performed a systematic review of studies through PubMed, followed by a manual search through the titles and abstracts (...) of original articles, including the reviews, commentaries and letters published in the last five years and dealing with the ethical and social issues raised by NGS technologies and genomics studies of mental disorders, especially BD. A total of 217 studies contributed to identify the themes discussed herein. Results The amount of information generated by NGS renders individuals suffering from BD particularly vulnerable, and increases the need for educational support throughout the consent process, and, subsequently, of genetic counselling, when communicating individual research results and incidental findings to them. Our results highlight the importance and difficulty of respecting participants’ autonomy while avoiding any therapeutic misconception. We also analysed the need for specific regulations on the use and communication of incidental findings, as well as the increasing influence of NGS in health care. Conclusions Shared efforts on the part of researchers and their institutions, Research Ethics Boards as well as participants’ representatives are needed to delineate a tailored consent process so as to better protect research participants. However, health care professionals involved in BD care and treatment need to first determine the scientific validity and clinical utility of NGS-generated findings, and thereafter their prevention and treatment significance. (shrink)

This article defends the principle of sufficient reason (PSR) from a simple and direct valid argument according to which PSR implies that there is a truth that explains every truth, namely an omni-explainer. Many proponents of PSR may be willing to bite the bullet and maintain that, if PSR is true, then there is an omni-explainer. I object to this strategy by defending the principle that explanation is irreflexive. Then I argue that proponents of PSR can resist the conclusion that (...) there is an omni-explainer by denying that explanation distributes over conjunction. In the final section, I consider a plausible revision of this assumption. I argue there that, given the revised assumption, PSR seems to yield a striking picture of the explanatory structure of the universe. I explain why the resulting model does not appear utterly implausible to me. (shrink)

Bringing Pierre Bourdieu to Science and Technology Studies Content Type Journal Article Pages 263-273 DOI 10.1007/s11024-011-9174-2 Authors Mathieu Albert, Wilson Centre and Department of Psychiatry, Faculty of Medicine, University of Toronto, 200 Elizabeth Street , Eaton-South 1-581, Toronto, ON M5G 2C4, Canada Daniel Lee Kleinman, Department of Community and Environmental Sociology, University of Wisconsin-Madison, 348 Agricultural Hall 1450 Linden Drive, Madison, WI 53706, USA Journal Minerva Online ISSN 1573-1871 Print ISSN 0026-4695 Journal Volume Volume 49 Journal Issue Volume 49, (...) Number 3. (shrink)

This chapter is concerned with the coextension difficulty for nominalist theories of properties that reject tropes alongside universals. After carefully explaining the coextension difficulty and describing the theories it targets, the chapter describes different solutions to the difficulty. These solutions differ with respect to how much involved they are into a dualist approach to coextension. A dualist approach to a case of coextension consists in agreeing with the realist that the relevant ascriptions of properties are numerically distinct. A monist approach (...) to a case of coextension consists in contending that the relevant ascriptions of properties are identical. In this chapter, I defend a monist approach to cases of coextension that appeals to a counterpart theory for propositions. (shrink)

This text presents and addresses the philosophical movement of antiphilosophy working thru the texts of Christian thinkers such as Pascal and Kierkegaard. The author as influenced by Alain Badiou, portrays these Christian thinkers as of a subjective dimension negating the possibility of an objective quest for truth. The claim here is that antiphilosophy is abundant in the eyes of these two thinkers who frame the thought event as represented by Christianity, ultimately resigning itself to more or less the opposite of (...) philosophy itself. Readers will discover why philosophical reason should never be convinced by that which denies its very authority. Subjecting faith to the perils of philosophical analysis, confronting the philosophical tradition with the truth of the Christian faith, and occupying the space between the two: such are the challenges facing an antiphilosophy of Christianity. This text will appeal to researchers and students working in continental philosophy, philosophy of religion and those in religious studies who want to investigate the links between Christianity and antiphilosophy. (shrink)

This book is the first of its kind to offer a new definition of contemporary management. It uses Michel Henry’s philosophy and takes the real, sensitive and pathetic subjectivity of individuals as the starting point of the analysis as opposed to the usual large categories of representations; resources; images; and discourses. This book thus proposes to rethink management by insisting on the dialectic of strength and vulnerability; its power of constraint, imitation and imagination; and finally its framework of action situated (...) in a fourfold concern for the self, for people, for institutions and for the environment. These different notions are useful in order to experience a deeper understanding of management that is free from the obsolescence of the distant recommendations of ancient protomanagement and the outdated and dubious prescriptions of the so-called “scientific management”. (shrink)

The culmination of three decades of studying and treating survivors of adult onset trauma, _Wounded by Reality_ is the first systematic attempt to differentiate adult onset trauma from childhood trauma, with which it is frequently confused. When catastrophic events overtake adult lives, they often scar the psyche in ways that psychodynamically oriented clinicians struggle to understand. For Ghislaine Boulanger, the enormous challenge of working with these patients is unsurprising. Survivors of major catastrophe, whether a natural disaster, a life-threatening assault, (...) a serious accident, or an act of terrorism, experience a near-fatal disruption of fundamental aspects of self experience. The sense of agency, of affectivity, of bodily integrity, the capacity for self-reflection, the sense of time, and the ability to relate to others - all are called into question. (shrink)

The influence of Jules Lequier on the development of continental philosophy is currently being revived. Ghislain Deslandes introduces Lequier's thought while highlighting its influence in the development, throughout the twentieth century, including in process thought, pragmatism, existentialism, and phenomenology.

Un temps de crise grave peut devenir un moment de grande espérance. Nous savons aujourd'hui que la civilisation du logos sous laquelle l'Occident vit depuis près de trois mille ans, dans une dialectique constante entre philosophie et christianisme, arrive à un point à la fois d'accomplissement et d'épuisement. Elle avait d'abord donné sa confiance à des explications englobantes. Celles-ci ont trouvé, dans l'Antiquité, leur forme quasi idéale : le logos avait pris alors un tour mystique et débouchait vers un Au-delà (...) de tout, qui n'a laissé indifférent ni l'islam ni le christianisme. Dans la modernité, il s'était organisé de manière parfaitement immanente ou soigneusement historique. A présent, il continue son chemin, mais devant l'épuisement des idées et des constructions qui lui donnaient corps et sens, il ne conserve que son armature essentiellement mathématique, dépouillée de toute réalité, sinon celle du nombre - ce que, dans notre langage actuel, nous appelons le " virtuel ". Nous pouvons recueillir aujourd'hui l'efficacité de ces pensées et pratiques pénétrées de la dynamique du Tout et du Rien. Mais, au point où nous en sommes actuellement, il y a une vraie menace que le Tout bascule vraiment dans le Rien et que nous allions à la catastrophe éthique, humaine, cosmique. Il a manqué sans doute à cette civilisation le respect du Quelque chose : ni tout, ni rien, mais substance, action, relation. Ici Aristote, dans l'Antiquité, et Thomas d'Aquin, au seuil de la modernité, peuvent venir à notre secours et nous aider à retrouver notre épaisseur d'homme, à ne pas fuir le jeu étrange en nous de la matière pénétrée de ce que nous appelons esprit, qui à la fois lui est immanent et la dépasse, à restituer par là un humanisme et une approche non aliénante du divin. Il y a sans doute là un motif d'espérance. Mais ce grand motif d'espérance réside surtout dans le tournant anthropologique contemporain : nous comprenons aujourd'hui que l'homme n'existe pas en réalité sans son frère qui lui parle. A la lumière de cette conversation essentielle, on doit pouvoir définir un humanisme et une politique ; une perspective s'ouvre aussi pour réinterpréter la religion et particulièrement le christianisme. À l'horizon apparaissent le symbole, la relation, la mort et la résurrection, l'amour. (shrink)

The music in here--. Music as body ; Music as mind ; Music as heart ; Feeling mind, thinking heart -- --out there--. Music as life ; Music as story ; Music as mirror -- --and everywhere--. Music on the Zen elevator ; The enlightened listener ; Living the waves.

This book offers a comparative study of the management of legal pluralism. The authors describe and analyse the way state and non-state legal systems acknowledge legal pluralism - defined as the coexistence of a state and non-state legal systems in the same space in respect of the same subject matter for the same population - and determine its consequences for their own purposes. The book sheds light on the management processes deployed by legal systems in Africa, Canada, Central Europe and (...) the South Pacific, the multitudinous factors circumscribing the action of systems and individuals with respect to legal pluralism, and the effects of management strategies and processes on systems as well as on individuals. The book offers fresh practical and analytical insight on applied legal pluralism, a fast-growing field of scholarship and professional practice. Drawing from a wealth of original empirical data collected in several countries by a multilingual and multidisciplinary team, it provides a thorough account of the intricate patterns of state and non-state practices with respect to legal pluralism. As the book's non-prescriptive approach helps to uncover and evaluate several biases or assumptions on the part of policy makers, scholars and development agencies regarding the nature and the consequences of legal pluralism, it will appeal to a wide range of scholars and practitioners in law, development studies, political science and social sciences. (shrink)

Le devenir du Nombre c'est le nôtre. Dans ce qui s'énonce ici sous la forme du traité, le Nombre est la puissance d'abstraction, de quantification, d'uniformisation déployée par les nombres quand le genre humain les anime. La Technosmose, le Fonctionnement, la logosynthèse, le Bios, sont quelques-unes des notions inédites qui coordonnent cet avènement. Remonter le cours de l'évolution du Nombre permet de comprendre l'établissement et la nature de son hégémonie. Le Nombre est désormais actif bien au-delà du phénomène de la (...) numérisation technologique: le monde le métabolise, et ce processus innerve la mutation planétaire en cours. Le crépuscule s'envisage alors sous les latitudes où il est une aurore. (shrink)

Une présentation de l'intérêt accordé aux religions par le philosophe Bergson à la fin de sa vie et notamment au christianisme.

A Polish space is not always homeomorphic to a computably presented Polish space. In this article, we examine degrees of non-computability of presenting homeomorphic copies of compact Polish spaces. We show that there exists a $\mathbf {0}'$ -computable low $_3$ compact Polish space which is not homeomorphic to a computable one, and that, for any natural number $n\geq 2$, there exists a Polish space $X_n$ such that exactly the high $_{n}$ -degrees are required to present the homeomorphism type of $X_n$. (...) Along the way we investigate the computable aspects of Čech homology groups. We also show that no compact Polish space has a least presentation with respect to Turing reducibility. (shrink)

According to Clifford Geertz, the purpose of anthropology is not to explain culture but to explicate it. That should cause us to rethink our relationship with machine learning. It is, we contend, perfectly possible that machine learning algorithms, which are unable to explain, and could even be unexplainable themselves, can still be of critical use in a process of explication. Thus, we report on an experiment with anthropological AI. From a dataset of 175K Facebook comments, we trained a neural network (...) to predict the emoji reaction associated with a comment and asked a group of human players to compete against the machine. We show that a) the machine can reach the same accuracy as the players, b) it fails in roughly the same ways as the players, and c) easily predictable emoji reactions tend to reflect unambiguous situations where interpretation is easy. We therefore repurpose the failures of the neural network to point us to deeper and more ambiguous situations where interpretation is hard and explication becomes both necessary and interesting. We use this experiment as a point of departure for discussing how experiences from anthropology, and in particular the tension between formalist ethnoscience and interpretive thick description, might contribute to debates about explainable AI. (shrink)

Nominalism, which has its origins in the Middle Ages and continues into the Twenty-First Century, is the doctrine that there are no universals. This book is unique in bringing together essays on the history of nominalism and essays that present a systematic discussion of nominalism. It introduces the reader to the distinction between particulars and universals, to the difficulties posed by this distinction, and to the main motivations for the rejection of universals. It also describes the main varieties of nominalism (...) about properties and provides tools to understand how they developed in the history of Western Philosophy. All essays are new and are written by experts on the topic, and they advance the discussion about nominalism to a new level. (shrink)

Que serait une exposition qui, au lieu de prendre place dans un musée ou dans une galerie, prendrait place au cinéma? (un projet de Mathieu Copeland, avec Chantal Akerman, Peter Downsbrough, Liam Gillick, John Giorno, Philippe Grandrieux, Isidore Isou, Philippe-Alain Michaud, Meredith Monk, Lee Ranaldo, Susan Stenger, Alan Vega, Jacques Villeglé, Lawrence Weiner, Apichatpong Weerasethakul...).

The second German edition of Capital appeared in nine issues, from July 1872 to March 1873. Marx added an afterword in which he hoped to answer his western European critics, whom he felt did not grasp his work. To understand the afterword to the second German edition of Capital, one must take into account both what Marx wrote in his book and what Marx’s British, French, German and Russian critics said about his work between 1867 and 1872.

Cet article s’intéresse au marché de l’édition scientifique et à son évolution dans le cadre de l’Internet et du développement du libre accès. Il s’attache à montrer la diversité de ce marché en fonction des champs scientifiques, notamment par le type d’éditeurs impliqués, les lectorats concernés, les économies associées. Il met en exergue le nécessaire discernement de ces marchés face aux critiques générales de dysfonctionnement soulignées. Il pointe certains effets contrastés du numérique conduisant à certaines reconfigurations paradoxales. Enfin, la vision (...) prospective sur le devenir de ce marché insiste sur la pluralité des modalités de progression vers le libre accès, le poids de la dimension politique et celui des processus d’évaluation de la recherche. La voie d’un partenariat public-privé est privilégiée au regard de certaines valeurs centrales : indépendance, qualité, accessibilité et pérennité des publications scientifiques.This article investigates the scientific publishing market and how it is being transformed by the Internet and the development of open-access services. We illustrate the diversity of the market in terms of scientific fields, and especially in the types of publishers and readerships concerned, and of the associated economics. In view of the sweeping criticisms of dysfunctional practices illustrated in the article, we alert readers as to the need for discernment among these markets. The article points to a number of contrasting effects of digital publishing that are leading to various paradoxical reconfigurations. Finally, this forward-looking study of the publishing market’s future emphasises the multiple forms of the onward march towards open access and the influence exerted by the political dimension and the research evaluation process. Public-private partnerships are the preferred option to cater for the central values of independence, quality, accessibility and the enduring nature of scientific publications. (shrink)

This paper investigates whether accounting professionals’ ethical judgment is influenced by the disciplinary system established by the accounting profession in France and the United States. Our study first attempts to determine whether there is a link between the EJ of accounting professionals and the disciplinary context, in each country. It then performs a comparative analysis of the two nations. Our findings indicate that the judgment of American accounting professionals is correlated with the disciplinary decisions of the accountancy board. By contrast, (...) the judgment of French accounting professionals is independent of the disciplinary context. Whereas cross-national studies have thus far attributed differences among nations mainly to cultural distance, current research shows that non-cultural national factors should also be considered. In line with this perspective, our study suggests that institutional factors, in particular the disciplinary system, may also account for the differences between French and American accounting professionals’ ethical perceptions. We support these results by highlighting some characteristics of the countries’ respective legal systems, which may explain the divergences observed. We conclude by identifying implications for the independence of accounting professionals’ EJ and the risks associated with dissuasive disciplinary systems. (shrink)

I call anti-resemblism the thesis that independently of any contextual specification there is no determinate fact of the matter about the comparative overall similarity of things. Anti-resemblism plays crucial roles in the philosophy of David Lewis. For instance, Lewis has argued that his counterpart theory is anti-essentialist on the grounds that counterpart relations are relations of comparative overall similarity and that anti-resemblism is true. After Lewis committed himself to a form of realism about natural properties he maintained that anti-resemblism is (...) true about the relations of overall similarity that enter his counterpart theory and his analysis of counterfactuals. However, in this article I argue that Lewis’s account of degrees of naturalness for properties combined with his modal realism entails that anti-resemblism is false. The Lewisian must amend Lewis’s system if she aims to benefit from the alleged virtues of anti-resemblism. I consider two ways of amending it, neither of which is a free lunch. (shrink)