IntroductionWind instrument players sometimes suffer from erosion of the mucous membrane of the lip. This is caused by the action and pressure of the mouthpiece of the wind instrument against teeth. To address this problem, a lip shield is fitted over the dental arch to prevent direct contact between the lips and teeth. However, there are a few studies on the influence of the lip shield on the acoustics of wind instruments. The purpose of this study was to analyze the (...) psychoacoustics of a clarinet performance with the player wearing a custom-made soft lip shield to prevent mucosal erosion of the lower lip.Case DescriptionA lip shield was custom-made with a soft thermoplastic material for a female clarinetist who complained of mucosal erosion and pain of the lower lip. The psychoacoustics of her musical performance played in different dynamics, fortissimo, mezzo forte and pianissimo were analyzed, including loudness and sharpness. A self-evaluation questionnaire with items rated on a 10-point scale was administered. After wearing the lip shield, the patient reported that the mucosal erosion and pain of her lower lip when playing clarinet resolved. The lip shield had little effect on the loudness. There was a slight decrease in sharpness when the lip shield was worn compared to when it was not, describing the reduction of high frequencies. Furthermore, fewer variations in sharpness between the tones were observed.ConclusionThe results suggest that lip shields made of soft materials can eliminate mucosal erosion and pain of the lower lip while having little effect on performance, although, a slight change in timbre is possible. (shrink)

The discipline of nursing has long maintained that is has a unique contribution to make within the health care arena. This assertion of uniqueness lies in great part in the discipline's claim to a distinct body of knowledge. Nursing knowledge is characterized by diverse and multiple forms of knowing and underpins the work of all nurses, regardless of field of practice. Unfortunately, it has been challenging for the discipline to take full ownership of its epistemological diversity, largely due to factors (...) such as competing worldviews, and ideological and binary positioning. A philosophical middle ground stance is proposed as a way for the discipline to contemplate, discuss and develop nursing knowledge; a middle space that provides the freedom to consider competing worldviews while still allowing for the discipline to fully express itself in all of its epistemological diversity. In being able to enact its multiple forms of knowledge in a creative and open space that is open to different ideas and worldviews, not only can nursing take full ownership of its practice and its unique knowledge, it can also demonstrate how best to navigate an increasingly polarized world. In a world that is increasingly fixated on binary solutions and dualistic points of view, it is time for nursing to celebrate its epistemological diversity. (shrink)

七代目子孫が初めて語る...江戸時代、600以上の荒廃した農村を復興させた金次郎のとっておきの教え。運命を高める55の金言。.

This paper proposes a new method that can diagnose nodes which consist of a large scale structure system including intermitted fault and analyzes its capability through simulations for comparisons between our method and Adaptive DSD, one of on-line distributed diagnosis methods. Our method based on ideas of a disconnecter and token node. The disconnecter is a function to cope with an intermitted fault, while the token node can collect and exchange fault node informations from other token nodes. Our simulation results (...) have confirmed that an autonomous distributed diagnosis method with token node works well in many cases, however, in some cases where the length between normal nodes is more than two links, our method cannot diagnoses correctly. In addition to this result, the following advantages of our method are founded in comparison with the Adaptive DSD: (1) our method does not need global connections among nodes but need only two link connections; (2) our method can cope with intermitted fault; (3) our method require less information exchange than Adaptive DSD; and (4) our method can get a correct fault information faster than Adaptive DSD. (shrink)

A multimodal person representation contains information about what a person looks like and what a person sounds like. However, little is known about how children form these face-voice mappings. Here, we explored the possibility that two cognitive tools that guide word learning, a one-to-one mapping bias and fast mapping, also guide children’s learning about faces and voices. We taught 4- and 5-year-olds mappings between three individual faces and voices, then presented them with new faces and voices. In Experiment 1, we (...) found that children rapidly learned face-voice mappings from just a few exposures, and furthermore spontaneously mapped novel faces to novel voices using a one-to-one mapping bias (that each face can produce only one voice). In Experiment 2, we found that children’s face-voice representations are abstract, generalizing to novel tokens of a person. In Experiment 3, we found that children retained in memory the face-voice mappings that they had generated via inference (i.e., they showed evidence of fast mapping), and used these newly formed representations to generate further mappings between new faces and voices. These findings suggest that preschoolers’ rapid learning about faces and voices may be aided by biases that are similar to those that support word learning. (shrink)

This paper discusses verse 1074 of the Suttanipāta’s Upasīvamāṇavapucchā. While various interpretations of the verse are possible due to a lack of textual sources to draw from for interpretation, I attempt to understand this verse—which describes the state of nibbāna using the metaphor of an extinguished fire—through a philological examination of the text itself and other contemporary ones. Specifically, I focus on whether the verse implies that nibbāna takes place in the present life or at and after the end of (...) life by examining the compound nāmakāya and the phrase atthaṃ paleti that appear in it. Arguing that the former term is a dvandva meaning “name-and-body” and that the latter means “goes down”, I conclude that in this verse the Buddha is discussing nibbāna at and after the end of life. However, I do not deny that different interpretations are possible. When dealing with an ancient verse, the interpretation of one word can affect one’s understanding of the verse itself or the sutta overall, possibly leading to perspectives on early Buddhist thought completely different from the original meaning or original intention of the author of the sutta. Taking this into consideration, this paper adopts a meticulous approach to philologically examining early Pāli texts. (shrink)

A rare academic study on what John Rawls, Peter Singer, and Derek Parfit acknowledge as the finest book in ethics -- The Methods of Ethics. With a rather shocking conclusion that "none of us can match Sidgwick," Mariko Nakano-Okuno lucidly analyzes Henry Sidgwick's impacts on contemporary ethics.

The concept of emotion can be organized within a hypothetical space comprising a limited number of dimensions representing essential properties of emotion. The present study examined cultural influences on such conceptual structure by comparing the performance of emotion word classification between Japanese and Korean individuals. Two types of emotional words were used; central concepts, highly typical examples of emotion, and less typical peripheral concepts. Participants classified 30 words into groups based on conceptual similarity. MDS analyses revealed a three-dimensional structure with (...) valence, social engagement, and arousal dimensions for both cultures, with the valence dimension being the most salient one. The Japanese prioritized the social engagement over the arousal while the Koreans showed sensitivities to the arousal dimension. Although the conceptual structure was similar for the two countries, the weight of importance among the three dimensions seems to be different, reflecting each culture’s values and communication styles. (shrink)

In this article, 41 models of covariation detection from 2 × 2 contingency tables were evaluated against past data in the literature and against data from new experiments. A new model was also included based on a limiting case of the normative phi‐coefficient under an extreme rarity assumption, which has been shown to be an important factor in covariation detection (McKenzie & Mikkelsen, 2007) and data selection (Hattori, 2002; Oaksford & Chater, 1994, 2003). The results were supportive of the (...) new model. To investigate its explanatory adequacy, a rational analysis using two computer simulations was conducted. These simulations revealed the environmental conditions and the memory restrictions under which the new model best approximates the normative model of covariation detection in these tasks. They thus demonstrated the adaptive rationality of the new model. (shrink)

One of the concerns that citizen science shares with the evolving practice of precision medicine is how to approach oversight for N-of-1 or N-of-many-1’s research. In their target article, Wiggins...

This paper explores the theoretical basis of the third party’s duty of justice as to grave human rights violations, presenting role obligations as the best complement to the literature. It begins with discussions on agents of justice in duty-based theories, notably O’Neill’s account on global justice, and rights-based theories, which are both included in the institution-centred perspective. I claim that these studies have failed to consider an individual duty bearer’s motive, autonomous reasoning and integrity in relation to justice, all of (...) which constitute serious lacunae for the effective accomplishment of responsibility. To supplement, I introduce the distinction between responsibility and commitment, and acknowledge that combining the two is the desirable condition for recognising the duty of justice. Finally, I argue that the role obligations undertaken through personal acceptance of an institution-based role or a commitment-based role related to human rights norms adequately explain third parties’ duty to protect others from serious harm. (shrink)

Lysosomal positioning is an important factor in regulating cellular responses, including autophagy. Because proteins encoded by disease‐responsible genes are involved in lysosomal trafficking, proper intracellular lysosomal trafficking is thought to be essential for cellular homeostasis. In the past few years, the mechanisms of lysosomal trafficking have been elucidated with a focus on adapter proteins linking motor proteins to lysosomes. Here, we outline recent findings on the mechanisms of lysosomal trafficking by focusing on adapter protein c‐Jun NH2‐terminal kinase‐interacting protein (JIP) 4, (...) which plays a central role in this process, and other JIP4 functions and JIP family proteins. Additionally, we discuss neuronal diseases associated with aberrance in the JIP family protein. Accumulating evidence suggests that chemical manipulation of lysosomal positioning may be a therapeutic approach for these neuronal diseases. (shrink)

This study aims to investigate assortative mating based on mate value from male perspective. Male participants (132 Brazilian and 106 American) evaluated hypothetical “stimulus” males described in terms of physical attractiveness, social skills, and social status (each varied in high or low levels). Participants rated each stimulus and each stimulus' preferred mating partner on nine traits. The results showed that (1) positive assortative mating was expected in romantic relationships; (2) the stimulus ratings did not vary independently, suggesting that mate value (...) is the result of the interaction of the characteristics of individuals; and (3) that participants expected physically attractive and healthier female partners to pair with high-status male stimuli. The American and Brazilian mating expectations were similar, minor differences indicate that Brazilian participants considered men with high levels of social skills to be more ambitious and intelligent; American participants expected men of high status to be healthier; Brazilians expect men of high status to have more attractive faces, while Americans expected these men to possess more attractive bodies; and Brazilian participants assigned more attractive bodies to men of lower status. These differences reflect the influence of economic and cultural factors on the local environment. The study contributes to the understanding of the construction of market value and reveals that male expectations are in line with human mating preferences. The investigation of mating expectations can be a rich approach to investigate socio-cultural aspects that are related to mating in different cultures. (shrink)