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Manfred D. Laubichler [54]Manfred Dietrich Laubichler [1]
  1.  13
    Evolutionary developmental biology offers a significant challenge to the neo-Darwinian paradigm.Manfred D. Laubichler - 2010 - In Francisco José Ayala & Robert Arp (eds.), Contemporary debates in philosophy of biology. Malden, MA: Wiley-Blackwell. pp. 199–212.
    This chapter contains sections titled: Introduction A Brief History of Developmental Explanations of Phenotypic Evolution Research Questions of Evo‐Devo Unifying Themes of the Conceptual Basis of Evo‐Devo Conclusion: A Mechanistic Theory of Evo‐Devo Challenges the Modern Synthesis Postscript: Counterpoint References.
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  2.  28
    Quantitative Perspectives on Fifty Years of the Journal of the History of Biology.B. R. Erick Peirson, Erin Bottino, Julia L. Damerow & Manfred D. Laubichler - 2017 - Journal of the History of Biology 50 (4):695-751.
    Journal of the History of Biology provides a fifty-year long record for examining the evolution of the history of biology as a scholarly discipline. In this paper, we present a new dataset and preliminary quantitative analysis of the thematic content of JHB from the perspectives of geography, organisms, and thematic fields. The geographic diversity of authors whose work appears in JHB has increased steadily since 1968, but the geographic coverage of the content of JHB articles remains strongly lopsided toward the (...)
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  3.  35
    Computational Perspectives in the History of Science: To the Memory of Peter Damerow.Manfred D. Laubichler, Jane Maienschein & Jürgen Renn - 2013 - Isis 104 (1):119-130.
    Computational methods and perspectives can transform the history of science by enabling the pursuit of novel types of questions, dramatically expanding the scale of analysis , and offering novel forms of publication that greatly enhance access and transparency. This essay presents a brief summary of a computational research system for the history of science, discussing its implications for research, education, and publication practices and its connections to the open-access movement and similar transformations in the natural and social sciences that emphasize (...)
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  4.  34
    Form and function in Evo Devo: historical and conceptual reflections.Manfred D. Laubichler - 2009 - In Manfred D. Laubichler & Jane Maienschein (eds.), Form and Function in Developmental Evolution. Cambridge University Press. pp. 10.
  5.  31
    Character identification: The role of the organism.Gunter P. Wagner & Manfred D. Laubichler - 2000 - In Günter P. Wagner (ed.), The Character Concept in Evolutionary Biology. Academic Press. pp. 143--165.
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  6.  48
    COVID-19 heralds a new epistemology of science for the public good.Manfred D. Laubichler, Peter Schlosser, Jürgen Renn, Federica Russo, Gerald Steiner, Eva Schernhammer, Carlo Jaeger & Guido Caniglia - 2021 - History and Philosophy of the Life Sciences 43 (2):1-6.
    COVID-19 has revealed that science needs to learn how to better deal with the irreducible uncertainty that comes with global systemic risks as well as with the social responsibility of science towards the public good. Further developing the epistemological principles of new theories and experimental practices, alternative investigative pathways and communication, and diverse voices can be an important contribution of history and philosophy of science and of science studies to ongoing transformations of the scientific enterprise.
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  7.  31
    The varied lives of organisms: variation in the historiography of the biological sciences.Gerald L. Geison & Manfred D. Laubichler - 2001 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 32 (1):1-29.
  8.  34
    The varied lives of organisms: variation in the historiography of the biological sciences.Gerald L. Geison & Manfred D. Laubichler - 2001 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 32 (1):1-29.
    This paper emphasizes the crucial role of variation, at several different levels, for a detailed historical understanding of the development of the biomedical sciences. Going beyond valuable recent studies that focus on model organisms, experimental systems and instruments, we argue that all of these categories can be accommodated within our approach, which pays special attention to organismal and cultural variation. Our empirical examples are drawn in particular from recent historical studies of nineteenth- and early twentieth-century genetics and physiology. Based on (...)
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  9.  94
    Organism and character decomposition: Steps towards an integrative theory of biology.Manfred D. Laubichler & Günter P. Wagner - 2000 - Philosophy of Science 67 (3):300.
    In this paper we argue that an operational organism concept can help to overcome the structural deficiency of mathematical models in biology. In our opinion, the structural deficiency of mathematical models lies mainly in our inability to identify functionally relevant biological characters in biological systems, and not so much in a lack of adequate mathematical representations of biological processes. We argue that the problem of character identification in biological systems is linked to the question of a properly formulated organism concept. (...)
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  10.  59
    The Organism is dead. Long live the organism!Manfred D. Laubichler - 2000 - Perspectives on Science 8 (3):286-315.
  11. Evolutionary developmental biology.Manfred D. Laubichler - 2007 - In David L. Hull & Michael Ruse (eds.), The Cambridge Companion to the Philosophy of Biology. New York: Cambridge University Press.
  12.  66
    Systems bioethics and stem cell biology.Jason Scott Robert, Jane Maienschein & Manfred D. Laubichler - 2006 - Journal of Bioethical Inquiry 3 (1-2):19-31.
    The complexities of modern science are not adequately reflected in many bioethical discussions. This is especially problematic in highly contested cases where there is significant pressure to generate clinical applications fast, as in stem cell research. In those cases a more integrated approach to bioethics, which we call systems bioethics, can provide a useful framework to address ethical and policy issues. Much as systems biology brings together different experimental and methodological approaches in an integrative way, systems bioethics integrates aspects of (...)
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  13.  50
    Biocomplexity as a Challenge for Biological Theory.Werner Callebaut & Manfred D. Laubichler - 2007 - Biological Theory 2 (1):1-2.
  14.  17
    Form and Function in Developmental Evolution.Manfred D. Laubichler & Jane Maienschein (eds.) - 2009 - Cambridge University Press.
    This book represents an effort to understand very old questions about biological form, function, and the relationships between them. The essays collected here reflect the diversity of approaches in evolutionary developmental biology, including not only studies by prominent scientists whose research focuses on topics concerned with evolution and development, but also historically and conceptually oriented studies that place the scientific work within a larger framework and ask how it can be pushed further. Topics under discussion range from the use of (...)
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  15.  33
    The Specter of the Past: What the History of Theoretical Biology Means Today.Manfred D. Laubichler - 2007 - Biological Theory 2 (2):131-133.
  16.  45
    The diversity of experimental organisms in biomedical research may be influenced by biomedical funding.B. R. Erick Peirson, Heather Kropp, Julia Damerow & Manfred D. Laubichler - 2017 - Bioessays 39 (5):1600258.
    Contrary to concerns of some critics, we present evidence that biomedical research is not dominated by a small handful of model organisms. An exhaustive analysis of research literature suggests that the diversity of experimental organisms in biomedical research has increased substantially since 1975. There has been a longstanding worry that organism‐centric funding policies can lead to biases in experimental organism choice, and thus negatively impact the direction of research and the interpretation of results. Critics have argued that a focus on (...)
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  17.  37
    Genetic= Heritable (Genetic# DNA).Root Gorelick & Manfred D. Laubichler - 2008 - Biological Theory 3 (1):79-84.
  18.  20
    Introduction.Abraham Gibson, Manfred D. Laubichler & Jane Maienschein - 2019 - Isis 110 (3):497-501.
    Digital technologies have transformed both the historical record and the historical profession. This Focus section examines how computational methods have influenced, and will influence, the history of science. The essays discuss the new types of questions and narratives that computational methods enable and the need for better data management in the history and philosophy of science (HPS) community. They showcase various methodological approaches, including textual and network analyses, and they place the computational turn in historiographical and societal context. Rather than (...)
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  19.  24
    Computational History of Knowledge: Challenges and Opportunities.Manfred D. Laubichler, Jane Maienschein & Jürgen Renn - 2019 - Isis 110 (3):502-512.
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  20.  12
    Philosophy of Biology, Psychology, and Neuroscience-The Organism in Philosophical Focus-Organism and Character Decomposition: Steps Towards an Integrative Theory of Biology.Manfred D. Laubichier, Manfred D. Laubichler & Gunter P. Wagner - 2000 - Philosophy of Science 67 (3):S289-S300.
    In this paper we argue that an operational organism concept can help to overcome the structural deficiency of mathematical models in biology. In our opinion, the structural deficiency of mathematical models lies mainly in our inability to identify functionally relevant biological characters in biological systems, and not so much in a lack of adequate mathematical representations of biological processes. We argue that the problem of character identification in biological systems is linked to the question of a properly formulated organism concept. (...)
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  21.  26
    Conrad Hal Waddington: Forefather of Theoretical EvoDevo.Brian K. Hall & Manfred D. Laubichler - 2008 - Biological Theory 3 (3):185-187.
  22.  36
    August Weismann and Theoretical Biology.Manfred D. Laubichler & Hans-Jörg Rheinberger - 2006 - Biological Theory 1 (2):195-198.
  23.  70
    The strategy concept and John Maynard Smith’s influence on theoretical biology.Manfred D. Laubichler, Edward H. Hagen & Peter Hammerstein - 2005 - Biology and Philosophy 20 (5):1041-1050.
    Here we argue that the concept of strategies, as it was introduced into biology by John Maynard Smith, is a prime illustration of the four dimensions of theoretical biology in the post-genomic era. These four dimensions are: data analysis and management, mathematical and computational model building and simulation, concept formation and analysis, and theory integration. We argue that all four dimensions of theoretical biology are crucial to future interactions between theoretical and empirical biologists as well as with philosophers of biology.
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  24.  35
    A semiotic perspective on biological objects and biological functions.Manfred D. Laubichler - 1999 - Semiotica 127 (1-4):415-432.
  25.  53
    Symposium “The Organism in Philosophical Focus”—An Introduction.Manfred D. Laubichler - 2000 - Philosophy of Science 67 (3):259.
  26.  31
    Formalizing Biology.Werner Callebaut & Manfred D. Laubichler - 2008 - Biological Theory 3 (1):1-2.
    Ioannidis [Why most published research findings are false. PLoS Med 2: e124 ] identifies six factors that contribute to explaining why most of the current published research findings are more likely to be false than true, and argues that for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias. In this article, we argue that three “hot” areas in current biological research, viz., agent-based modeling, evolutionary developmental biology, and systems biology, are especially (...)
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  27.  18
    The Moody’s Virus Attacks the U.S. National Science Board.Werner Callebaut & Manfred D. Laubichler - 2010 - Biological Theory 5 (1):1-2.
  28.  74
    Conrad H. Waddington: Towards a Theoretical Biology.Brian K. Hall & Manfred D. Laubichler - 2008 - Biological Theory 3 (3):233-237.
  29.  34
    Relatedness: Capturing Cohesion in Biological Systems.Jürgen Gadau & Manfred D. Laubichler - 2006 - Biological Theory 1 (4):414-417.
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  30.  23
    Biology Integrating Scientific Fundamentals: Contributions to the History of Interrelations between Biology, Chemistry, and Physics from the Eighteenth to the Twentieth Centuries. Brigitte Hoppe.Manfred D. Laubichler - 2001 - Isis 92 (4):761-762.
  31.  39
    Does EvoDevo Equal Regulatory Evolution?Manfred D. Laubichler - 2006 - Biological Theory 1 (1):102-103.
  32. Essay Review-How Constructive is Deconstruction?Manfred D. Laubichler & Angela N. H. Creager - 1999 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 30 (1):129.
     
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  33.  25
    “General Biology” Old and New: The Challenges Facing Biological Explanation.Manfred D. Laubichler & Werner Callebaut - 2007 - Biological Theory 2 (4):329-331.
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  34.  8
    Homo Cerebralis: Der Wandel vom Seelenorgan zum Gehirn. Michael Hagner.Manfred D. Laubichler - 2000 - Isis 91 (1):140-141.
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  35.  25
    The Camel's Nose: Memoirs of a Curious Scientist. Knut Schmidt-Nielsen.Manfred D. Laubichler - 1999 - Isis 90 (3):622-624.
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  36.  16
    The regulatory genome: Eric Davidson at 70.Manfred D. Laubichler - 2007 - Bioessays 29 (9):937-939.
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  37. Wider den Revolutionszwang!Manfred D. Laubichler - 1995 - Ethik Und Sozialwissenschaften 6 (3):333.
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  38.  25
    Where is Theoretical Biology Heading?Manfred D. Laubichler - 2007 - Biological Theory 2 (2):210-212.
  39.  24
    D-618.Gerd B. Müller, Manfred D. Laubichler, Peter Hammerstein, Linnda R. Caporael & Werner Callebaut - 2006 - Biological Theory 1 (4):331-332.
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  40.  24
    The Problem of Origins.Gerd B. Müller, Manfred D. Laubichler, Peter Hammerstein, Linnda R. Caporael & Werner Callebaut - 2006 - Biological Theory 1 (2):111-111.
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  41.  75
    The Strategic View of Biological Agents.Peter Hammerstein, Edward H. Hagen & Manfred D. Laubichler - 2006 - Biological Theory 1 (2):191-194.
  42.  34
    From Cells to Systems: Conceptual Abstractions of Biological Building Blocks.Werner Callebaut & Manfred D. Laubichler - 2007 - Biological Theory 2 (2):117-118.
  43.  46
    Risking Deeper Integration.Werner Callebaut, Linnda R. Caporael, Peter Hammerstein, Manfred D. Laubichler & Gerd B. Müller - 2006 - Biological Theory 1 (1):1-3.
  44.  55
    Agents, Modeling Processes, and the Allure of Prophecy.William A. Griffin, Manfred D. Laubichler & Werner Callebaut - 2008 - Biological Theory 3 (1):73-78.
    Ioannidis [Why most published research findings are false. PLoS Med 2: e124 ] identifies six factors that contribute to explaining why most of the current published research findings are more likely to be false than true, and argues that for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias. In this article, we argue that three “hot” areas in current biological research, viz., agent-based modeling, evolutionary developmental biology , and systems biology, are (...)
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  45. How molecular is molecular developmental biology? A reply to Alex Rosenberg's reductionism redux: Computing the embryo. [REVIEW]Manfred D. Laubichler & Günter P. Wagner - 2001 - Biology and Philosophy 16 (1):53-68.
    This paper argues in defense of theanti-reductionist consensus in the philosophy ofbiology. More specifically, it takes issues with AlexRosenberg's recent challenge of this position. Weargue that the results of modern developmentalgenetics rather than eliminating the need forfunctional kinds in explanations of developmentactually reinforce their importance.
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  46.  39
    The Embryo Project: An Integrated Approach to History, Practices, and Social Contexts of Embryo Research. [REVIEW]Jane Maienschein & Manfred D. Laubichler - 2010 - Journal of the History of Biology 43 (1):1 - 16.
    This essay describes the approach and early results of the collaborative Embryo Project and its on-line encyclopedia. The project is based on a relational database that allows federated searches and inclusion of multiple types of objects targeted for multiple user groups. The emphasis is on the history and varied contexts of developmental biology, focusing on people, places, institutions, techniques, literature, images, and other aspects of study of embryos. This essay introduces the ways of working as well as the long-term goals (...)
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  47.  23
    Die Geschichte der genetisch orientierten Hirnforschung von Cecile und Oskar Vogt in der Zeit von 1895 bis ca. 1927. Helga Satzinger. [REVIEW]Manfred D. Laubichler - 1999 - Isis 90 (2):394-395.
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  48.  15
    Frederick B. Churchill. August Weismann: Development, Heredity, and Evolution. xii + 700 pp., illus., app., index. Cambridge, Mass.: Harvard University Press, 2015. $49.95 . ISBN 9780674736894. [REVIEW]Manfred D. Laubichler - 2019 - Isis 110 (3):620-621.
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  49.  19
    Matthias Dörries . Michael Frayn’s Copenhagen in Debate: Historical Essays and Documents on the 1941 Meeting between Niels Bohr and Werner Heisenberg. viii + 195 pp., illus., bibl., index. Berkeley: Office for History of Science and Technology, University of California, Berkeley, 2005. $12. [REVIEW]Manfred D. Laubichler - 2007 - Isis 98 (2):401-402.
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  50.  3
    Maurizio Meloni. Political Biology: Science and Social Values in Human Heredity from Eugenics to Epigenetics. xi + 284 pp., tables, bibl., index. New York: Palgrave Macmillan, 2016. $105 . ISBN 9781137377722. [REVIEW]Manfred D. Laubichler - 2019 - Isis 110 (3):645-646.
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