BackgroundMulti-centre studies generally cost more than single-centre studies because of larger sample sizes and the need for multiple ethical approvals. Multi-centre studies include clinical trials, clinical quality registries, observational studies and implementation studies. We examined the costs of two large Australian multi-centre studies in obtaining ethical and site-specific approvals.MethodsWe collected data on staff time spent on approvals and expressed the overall cost as a percent of the total budget.ResultsThe total costs of gaining approval were 38 % of the budget for (...) a study of 50 centres (mean cost AUD $6960 per site) and 2 % for a study of 11 centres (mean cost AUD $2300 per site). Seventy-five and 90 % of time was spent on repeated tasks, respectively, and many time-consuming tasks, such as reformatting documents, did nothing to improve the study design or participant safety.ConclusionsImprovements have been made to the ethical approval application system, but more gains could be made without increasing risks of harm to research participants. We propose that ethical review bodies and individual sites publish statistics on how long they take to process approvals which could then be nationally benchmarked. (shrink)

The choice to undertake a PhD is essentially the choice of an individual to complete an individual task that carries the name of the researcher as the cognitive authority and reinforces the place of their respective University within the western academy, with all of the structure of power and authority that comes along with that. But what happens when the research itself takes place in an intercultural space, and the rules and values of the academic space stand in contrast to (...) the rules and values of the cultural space that is being inhabited? How does a PhD student fulfill their contract with the University while still embarking on morally responsible work with the research participants that has at its core existing relationships and a collective concern? How might an exploration of these issues open a window to new ways of doing research in culturally complex spaces? This article explores how one non-Indigenous PhD candidate working in an intercultural space with Indigenous research participants is unpac.. (shrink)

Donald Davidson has posed the problem of first-person authority and provided his own solution to it. He has argued that no epistemic theory of first-person authority can resolve the problem, but that a theory that appeals to constraints on interpreting speech can. We argue that Davidson is wrong about epistemic theories and that his own theory of first-person authority is inadequate. We propose an alternative based on the epistemic constraints associated with embodiment and argue that recognition of these constraints undermines (...) Davidson's position. (shrink)