In this paper, we hypothesize that X chromosome‐associated mechanisms, which affect X‐linked genes and are behind the immunological advantage of females, may also affect X‐linked microRNAs. The human X chromosome contains 10% of all microRNAs detected so far in the human genome. Although the role of most of them has not yet been described, several X chromosome‐located microRNAs have important functions in immunity and cancer. We therefore provide a detailed map of all described microRNAs located on human and mouse X (...) chromosomes, and highlight the ones involved in immune functions and oncogenesis. The unique mode of inheritance of the X chromosome is ultimately the cause of the immune disadvantage of males and the enhanced survival of females following immunological challenges. How these aspects influence X‐linked microRNAs will be a challenge for researchers in the coming years, not only from an evolutionary point of view, but also from the perspective of disease etiology. (shrink)

In this paper, we hypothesize that X chromosome-associated mechanisms, which affect X-linked genes and are behind the immunological advantage of females, may also affect X-linked microRNAs. The human X chromosome contains 10% of all microRNAs detected so far in the human genome. Although the role of most of them has not yet been described, several X chromosome-located microRNAs have important functions in immunity and cancer. We therefore provide a detailed map of all described microRNAs located on human and mouse X (...) chromosomes, and highlight the ones involved in immune functions and oncogenesis. The unique mode of inheritance of the X chromosome is ultimately the cause of the immune disadvantage of males and the enhanced survival of females following immunological challenges. How these aspects influence X-linked microRNAs will be a challenge for researchers in the coming years, not only from an evolutionary point of view, but also from the perspective of disease etiology. (shrink)

This study is an attempt to construct a quantitative link for international regimes with global leadership. The country's willingness to lead in solving global issues as the first mover in the formation of an international regime is measured and characterized by analyzing their ratification behavior in multilateral conventions deposited to the United Nations which shape of the global community. For this purpose, a set of quantitative indicators, the Index of Global Leadership Willingness and the Global Support Index, was defined and (...) calculated for each country based on its actual ratification year data for 120 multilateral conventions covering global issues such as peace and security, environment, commerce, communication, intellectual property protection, human rights, and labor. By proposing a framework of global leadership analysis, the study seeks to provide an empirical testing of the transformation of global governance towards cooperation without hegemony paradigm. The paper analyses changes in the leadership willingness indices of selected country groups, such as the G3, G7/8, and G20, over the century and finds that the will to drive the international agenda of these groups of leaders is in decline. Moreover, our study provides evidence to argue that our current world is actually without consistent global leadership across domains of the world affairs. Although several countries still show visible leadership in specific policy domains, such as environment and intellectual property, neither the G7/8 nor the G20 was playing a comparable role to those performed by the G3 a hundred years ago. (shrink)

In order to usurp Party power and restore capitalism, the "gang of four" has deliberately confused Marxist theories and the people's thinking. "Bourgeois rights" under the socialist system is a question which has been greatly confused by the clique. Like [Max] Stirner who was denounced by Marx, they abused the concept of "bourgeois rights" "on any occasion" in the manner of "fleas hopping" and turned out their fantastic "rights economics.".

This article discusses how women’s travels in the early imperial period threatened the ‘natural’ socio-cultural hierarchy of the Roman upper-classes. In a first part, the main threads of the ideological discourse on female mobility will be mapped by means of an examination of a senatorial debate during the reign of Tiberius in Tacitus’ Annals, uncovering layers of meaning that have remained unnoticed. The second and third parts will be devoted to literary motifs that have shaped the characterizations of men and (...) women travellers to illustrate the extents to which Roman travel is gendered. Central to this examination is the Roman elite’s fear of the corrupting and disrupting power of the exotica of foreign nations and its effects on men’s and women’s Romanness. (shrink)

Ancient Chinese Encyclopedia of Technology: Translation and Annotation of the Kaogong ji. By Wenren Jun. Abingdon, UK: Routledge, 2018. Pp. xxviii + 525. $224 ; $49.95.

Volume 34, Issue 8, December 2020, Page 1591-1607.

W. H. Auden's dictum "poetry makes nothing happen" has an enduring currency in poetic criticism, quoted ad nauseam to support the view that poetic discourse must never fall subservient to political ends.1 Conventional wisdom would hold that Hugh MacDiarmid, a poet more often noted for his obstinate commitment to communism, patently failed to heed this dictum. Indeed, as Scott Lyall notes, MacDiarmid's political poems are almost never anthologized, suggesting that the poems in which MacDiarmid's political views are made explicit are (...) of inferior poetic quality.2Yet one must acknowledge that its subject matter cannot be taken as an... (shrink)

This paper explores food commoning through an ethnographic case study in Catalonia as our primary site while the Norwegian case is juxtaposed as a comparison, two agriculturally and economically different European countries. The ethnography analyses cooperation networks between organic food producers’ and consumers’ involving different nodes of community gardening initiatives, self-employed growers, local farmers and all of them under a unique cooperative integrating a community economy. The result it is a myriad of exchange practices ranging from reciprocity and barter to (...) market exchange without intermediaries through on-line platforms. Along these exchanges different options of currency intervene giving rise to novel social and cooperative relations. Similar initiatives in Norway show less variation and are less experimental regarding forms of payment but share similarities in relation to material articulations, concerns and forms of alternative practice. Although these novel forms do not represent a complete break from the more standardized supply chains, and hence from the oppositions/contradictions of production and consumption, the participants see themselves as contributing to a more general process of de-commodification of food. We explore the extent to which the meaning and moral values are mutually constituted in relation to socioeconomic exchanges and environmental caring that each person experiences based on different forms of cooperation and reciprocity. Food, we suggest, is more than a commodity on the market that we may influence through our role as consumers. It is a significant focal point connecting our lives to those of others that articulates one’s relations to society in a political manner. (shrink)

The paper attempts to construct a global model of a social contract using well-known metaphors of two great philosophers: Jean-Jacques Rousseau and John Locke. By modelling a global social contract, I mean the formulation of a social contract using two sets of data: one is global citizens' preferences about values and norms while the other is sovereign states' participation in multilateral treaties. Both Rousseau and Locke formulate their versions of social contract theories in the national context of eighteenth-century Europe. This (...) paper tries my hands on extending their theories to the global context. This paper attempts to link empirically the relationship between global citizens' preferences as gauged by the World Values Survey and sovereign states' participation in 120 multilateral treaties deposited to the United Nations. To see the link between citizens and treaties (quasi-legislative outcomes, sort of), dimensional similarities of the cosmos of citizens' preference and the cosmos of sovereign states' willingness to join multilateral treaties are examined. Once done, all the sovereign states are located in each of the two cosmoses, citizens and states, and the correlation coefficients between them are measured. Based on these empirical results, the nature of the global quasi-legislative process is clarified. Conclusions and implications are drawn. (shrink)

Presenting Descartes as a thinker who sought to reconcile his philosophical principles and Christianity, this work grasps this harmonization in terms of Eucharistic explanations, so as to identify the terms of articulation between his philosophy and the field of theology.

Penseur majeur de la gauche antitotalitaire, eclipsé partiellement par les grandes figures de Derrida, Barthes ou Lacan, Cornelius Castoriadis (1922-1997) est un penseur que l'on commence à peine à (re)découvrir, alors que ses écrits deviennent accessibles au public francophone. Tout à la fois philosophe, militant politique, économiste, psychanalyste, sociologue, anthropologue et connaisseur éclairé des arts et des mathématiques, il fournit des outils intellectuels pour appréhender certaines des questions brûlantes de notre époque (rôle de la religion dans la société, critique des (...) inégalités, place du biologique dans le comportement humain, etc.), tout en les restituant dans le fonctionnement social-historique des sociétés humaines en général. Son œuvre, partie du marxisme puis s'en détachant, tente de faire le lien entre la psyché individuelle et les significations imaginaires qui tiennent ensemble les groupes humains mais autorisent aussi, de ce fait, les ruptures et créations - rares certes, mais toujours possibles. (shrink)

Compositionality in Plant Fixed Expressions Shelley Ching-yu Hsieh, Chinfa Lien, Sebastian Meier Abstract This paper examines fixed expressions that contain plant names in Mandarin Chinese and German corpora. It aims to reveal the compositionality of the concepts of the vehicle flower by means of frame semantics, and then popular vehicles (plant names) and underlying conceits (the associations between vehicles and meanings) of plant fixed expressions in these two languages will be explored. The linguistic frames of flowers show that German (...) focuses on function by adopting usability and edibility of plants in their expressions, whereas Mandarin Chinese perceives outer appearance of plants and compile “visualized” Chinese expressions. People observe and perceive plants from different standpoints and thus compose different concepts in their minds and languages. Chinese vehicles fall mainly into the categories of trees and flowers, while German vehicles are fruits and divisions of plants such as seeds and roots. This confirms the functional and visual perspective of the respective languages and further suggests the individualism of the Germans as well as the holism of the Mandarin Chinese speakers. (shrink)