Results for 'Lawrence I. Golbe'

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  1.  89
    Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.Günter U. Höglinger, Nadine M. Melhem, Dennis W. Dickson, Patrick M. A. Sleiman, Li-San Wang, Lambertus Klei, Rosa Rademakers, Rohan de Silva, Irene Litvan, David E. Riley, John C. van Swieten, Peter Heutink, Zbigniew K. Wszolek, Ryan J. Uitti, Jana Vandrovcova, Howard I. Hurtig, Rachel G. Gross, Walter Maetzler, Stefano Goldwurm, Eduardo Tolosa, Barbara Borroni, Pau Pastor, P. S. P. Genetics Study Group, Laura B. Cantwell, Mi Ryung Han, Allissa Dillman, Marcel P. van der Brug, J. Raphael Gibbs, Mark R. Cookson, Dena G. Hernandez, Andrew B. Singleton, Matthew J. Farrer, Chang-En Yu, Lawrence I. Golbe, Tamas Revesz, John Hardy, Andrew J. Lees, Bernie Devlin, Hakon Hakonarson, Ulrich Müller & Gerard D. Schellenberg - unknown
    Progressive supranuclear palsy is a movement disorder with prominent tau neuropathology. Brain diseases with abnormal tau deposits are called tauopathies, the most common of which is Alzheimer's disease. Environmental causes of tauopathies include repetitive head trauma associated with some sports. To identify common genetic variation contributing to risk for tauopathies, we carried out a genome-wide association study of 1,114 individuals with PSP and 3,247 controls followed by a second stage in which we genotyped 1,051 cases and 3,560 controls for the (...)
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  2.  87
    Ansāb al-ashrāf by Aḥmad B. Yaḥyā B. Jābir al-Balādhurī, Vol. VIBAnsab al-ashraf by Ahmad B. Yahya B. Jabir al-Baladhuri, Vol. VIB. [REVIEW]Lawrence I. Conrad, Aḥmad B. Yaḥyā B. Jābir al-Balādhurī, Khalil Athamina & Ahmad B. Yahya B. Jabir al-Baladhuri - 1995 - Journal of the American Oriental Society 115 (4):733.
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  3. An Andalusian physician at the Court of the Muwahhids: some notes on the public career of Ibn Tufayl.Lawrence I. Conrad - 1995 - Al-Qantara 16 (1):3-14.
     
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  4.  15
    Arabic Legal and Administrative Documents in the Cambridge Genizah Collections.Lawrence I. Conrad & Geoffrey Khan - 1996 - Journal of the American Oriental Society 116 (1):153.
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  5.  5
    Catalogue of the Arabic Manuscripts in the Hellmut Ritter Microfilm Collection of the Uppsala University Library.Lawrence I. Conrad, Bernhard Lewin, Oscar Löfgren, Mikael Persenius & Oscar Lofgren - 1996 - Journal of the American Oriental Society 116 (1):152.
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  6.  10
    El legado cientifico andalusi. Juan Vernet, Julio Samso.Lawrence I. Conrad - 1996 - Isis 87 (2):347-348.
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  7.  26
    Islam and the sea: paradigms and problematics.Lawrence I. Conrad - 2002 - Al-Qantara 23 (1):123-154.
    El nuevo libro de Xavier de Planhol, L'Islam et la mer es el primer intento, por parte de un especialista occidental, de evaluar el papel del mar en el mundo islámico. No es un libro que se dedique a describir acontecimientos sino a establecer paradigmas culturales e intelectuales, llegando a la conclusión de que «el islam es incompatible con el mar». En consecuencia, explora las implicaciones de esta antipatía a lo largo de la historia islámica desde tiempos pre-islámicos hasta el (...)
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  8.  20
    Recovering Lost Texts: Some Methodological IssuesThe Making of the Last Prophet: A Reconstruction of the Earliest Biography of MuḥammadThe Making of the Last Prophet: A Reconstruction of the Earliest Biography of Muhammad.Lawrence I. Conrad & Gordon Darnell Newby - 1993 - Journal of the American Oriental Society 113 (2):258.
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  9.  10
    The Syriac Chronicle of Pseudo-Dionysus of Tel-Maḥrē: A Study in the History of HistoriographyThe Syriac Chronicle of Pseudo-Dionysus of Tel-Mahre: A Study in the History of Historiography.Lawrence I. Conrad & Witold Witakowski - 1990 - Journal of the American Oriental Society 110 (3):529.
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  10.  46
    The world of Ibn Ṭufayl: interdisciplinary perspectives on Ḥayy ibn Yaqẓān.Lawrence I. Conrad (ed.) - 1996 - New York: E.J. Brill.
    This collection of interdisciplinary essays on a unique work by a physician and political figure in 12th-century Spain and North Africa casts important light on the social and intellectual history of the period and breaks new ground in the critical assessment of medieval Arabic literary works.
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  11.  24
    Neuropeptides, second messengers and insect molting.Lawrence I. Gilbert, Wendell L. Combest, Wendy A. Smith, Victoria H. Meller & Dorothy B. Rountree - 1988 - Bioessays 8 (5):153-157.
    Insect molting is elicited by a class of polyhydroxylated steroids, ecdysteroids, that originate in the prothoracic glands. Ecdysteroid synthesis in the prothoracic glands is controlled in large measure by a peptide hormone from the brain, prothoracicotropic hormone (PTTH), which exists in two forms and is released into the general circulation as a result of environmental and developmental cues. The means by which PTTH activates the prothoracic glands has been examined at the cellular level and the data reveal the involvement of (...)
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  12.  8
    Mitochondrial genetics and human disease.Lawrence I. Grossman & Eric A. Shoubridge - 1996 - Bioessays 18 (12):983-991.
    Mitochondria contain a molecular genetic system to express the 13 protein components of the electron transport system encoded in the mitochondrial genome (mtDNA). Defects in the function of this system result in some diaseases, many of which are multisystem disorders, prominently involving highly aerobic, postmitotic tissues. These defects can be caused by large‐scale rearrangements of mtDNA, by point mutations, or by nuclear gene mutations resulting in abnormalities in mtDNA. Although any of these mutations would be expected to produce a similar (...)
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  13.  8
    Stem Cells, Embryos, and Casualties of War'Redux.I. Bonchek Lawrence - 2004 - Free Inquiry 24 (2):45.
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  14.  13
    Book Review: Earthquakes in the Middle East, the Seismicity of Egypt, Arabia and the Red SeaThe Seismicity of Egypt, Arabia and the Red Sea. AmbraseysN. N., MelvilleC. P. and AdamsR. D. . Pp. xx + 181. £60.00/$94.95. [REVIEW]Lawrence I. Conrad - 1995 - History of Science 33 (3):369-370.
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  15.  8
    Internal and external regulatory process and the ecology of motivation.Lawrence I. O'Kelly - 1979 - Behavioral and Brain Sciences 2 (1):112-113.
  16.  1
    Not just a pretty pair of wings.Robert Rybczynski & Lawrence I. Gilbert - 1997 - Bioessays 19 (2):183-184.
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  17.  9
    Not just a pretty pair of wings.Robert Rybczynski & Lawrence I. Gilbert - 1997 - Bioessays 19 (2):183-184.
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  18.  22
    The World of Ibn Ṭufayl: Interdisciplinary Perspectives on Ḥayy ibn YaqẓānThe World of Ibn Tufayl: Interdisciplinary Perspectives on Hayy ibn Yaqzan.Peter Heath & Lawrence I. Conrad - 1998 - Journal of the American Oriental Society 118 (3):413.
  19.  6
    The effect of response-contingent feedback stimuli under two types of avoidance extinction conditions.Cynthia Scheuer & Lawrence I. Schonfeld - 1979 - Bulletin of the Psychonomic Society 13 (6):383-386.
  20.  8
    The Byzantine and Early Islamic Near East, Vol. 1: Problems in the Literary Source Material.Robert Hoyland, Averil Cameron & Lawrence I. Conrad - 1994 - Journal of the American Oriental Society 114 (2):287.
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  21.  5
    Not just a pretty pair of wings.Marian R. Goldsmith, Adam S. Wilkins, Robert Rybczynski & Lawrence I. Gilbert - 1997 - Bioessays 19 (2):183-184.
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  22.  10
    Studies in Early Islamic History.Michael L. Bates, Martin Hinds, Jere Bacharach, Lawrence I. Conrad & Patricia Crone - 1998 - Journal of the American Oriental Society 118 (3):407.
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  23.  30
    Why decision making may not require awareness.I. P. L. McLaren, B. D. Dunn, N. S. Lawrence, F. N. Milton, F. Verbruggen, T. Stevens, A. McAndrew & F. Yeates - 2014 - Behavioral and Brain Sciences 37 (1):35-36.
  24. Tao Te Fa Chan Ti Che Hsüeh.Lawrence Kohlberg & Kuo Li Pien I. Kuan - 1986
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  25.  45
    The Relevance Thesis and the Trap of Mistakenly Strict Principles about Abortion.Lawrence Masek - manuscript
    I argue that physicians can save women from life-threatening pregnancies by performing a craniotomy, placentectomy, or salpingotomy without intending death or harm. To support this conclusion, I defend the relevance thesis about intentions (a person intends X only if X explains the action). I then criticize the identity thesis (if a person intends X and knows X is Y then the person intends Y) and three mistakenly strict moral principles: (1) one may not intend something that is a serious harm (...)
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  26. “Cultural Racism”: Biology and Culture in Racist Thought.Lawrence Blum - 2023 - Journal of Social Philosophy 54 (3):350-369.
    Observers have noted a decline (in the US) in attributions of genetically-based inferiority (e.g. in intelligence) to Blacks, and a rise in attributions of culturally-based inferiority. Is this "culturalism" merely warmed-over racism ("cultural racism") or a genuinely distinct way of thinking about racial groups? The question raises a larger one about the relative place of biology and culture in racist thought. I develop a typology of culturalisms as applied to race: (1) inherentist or essentialist culturalism (inferiorizing cultural characteristics wrongly but (...)
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  27.  34
    Lorentz Invariant Berry Phase for a Perturbed Relativistic Four Dimensional Harmonic Oscillator.Yossi Bachar, Rafael I. Arshansky, Lawrence P. Horwitz & Igal Aharonovich - 2014 - Foundations of Physics 44 (11):1156-1167.
    We show the existence of Lorentz invariant Berry phases generated, in the Stueckelberg–Horwitz–Piron manifestly covariant quantum theory (SHP), by a perturbed four dimensional harmonic oscillator. These phases are associated with a fractional perturbation of the azimuthal symmetry of the oscillator. They are computed numerically by using time independent perturbation theory and the definition of the Berry phase generalized to the framework of SHP relativistic quantum theory.
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  28. Nominalization, Specification, and Investigation.Richard Lawrence - 2017 - Dissertation, University of California, Berkeley
    Frege famously held that numbers play the role of objects in our language and thought, and that this role is on display when we use sentences like "The number of Jupiter's moons is four". I argue that this role is an example of a general pattern that also encompasses persons, times, locations, reasons, causes, and ways of appearing or acting. These things are 'objects' simply in the sense that they are answers to questions: they are the sort of thing we (...)
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  29.  26
    Logic and computation: interactive proof with Cambridge LCF.Lawrence C. Paulson - 1987 - New York: Cambridge University Press.
    Logic and Computation is concerned with techniques for formal theorem-proving, with particular reference to Cambridge LCF (Logic for Computable Functions). Cambridge LCF is a computer program for reasoning about computation. It combines methods of mathematical logic with domain theory, the basis of the denotational approach to specifying the meaning of statements in a programming language. This book consists of two parts. Part I outlines the mathematical preliminaries: elementary logic and domain theory. They are explained at an intuitive level, giving references (...)
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  30.  5
    Salomon Maimon, Gesamtausgabe. Band I,1: Aufsätze 1789–1790, ›Versuch über die Transscendentalphilosophie‹.Nicholas Lawrence - forthcoming - Journal of Transcendental Philosophy.
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  31.  8
    "I'm Not a Racist, But...".Lawrence Blum - 2002 - Ithaca: Cornell University Press.
    Media, politicians, and individuals often use the term "racism" casually and inaccurately, threatening to strip the concept of its meaning and moral force, argues Blum in "'I'm Not a Racist, But...': The Moral Quandary of Race". Not all racial incidents are racist incidents. Blum asserts that only "certain especially serious moral failings and violations" merit the designation "racism." Discussing various scholarly perspectives on the construction of racial categories, Blum calls for a balance between "ridding ourselves of the myth of race" (...)
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  32. Latinos on race and ethnicity : Alcoff, Corlett, and Gracia.Lawrence Blum - 2009 - In Susana Nuccetelli, Ofelia Schutte & Otávio Bueno (eds.), A Companion to Latin American Philosophy. Malden, MA: Wiley-Blackwell. pp. 269-282.
    This article explicates the views on both race and ethnicity of these three prominent Latinx philosophers, compares them (somewhat), and offers some criticisms. Corlett jettisons race as a categorization of groups, but accepts a form of racialization somewhat at odds with this jettisoning. Gracia adopts as a general principle that an account of both ethnicity and race should help us see aspects of reality that would otherwise be obscured; but this is at odds with his regarding the Latin American view (...)
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  33.  6
    Heidegger, Buber and Levinas: Must We Give Priority to Authenticity or Mutuality or Holiness?Lawrence Vogel - 2016 - In Lisa Foran & Rozemund Uljée (eds.), Heidegger, Levinas, Derrida: The Question of Difference. Cham: Springer Verlag.
    After considering Buber’s and Levinas’s critiques of Heidegger and of each other, I propose that we should acknowledge authenticity, “essential relations” of love and friendship, and holiness as aspects of a good life, though they pull in different directions. We should resist the temptation to take sides in a battle between different approaches to the complex nature of our social being.
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  34.  6
    Two religious critiques of liberal democracy: a comparison of the political theories of Mohandas Karamchand Gandhi and Franklin I. Gamwell.Johnson Lawrence - 2015 - Lampeter, Ceredigion, Wales, United Kingdom: Edwin Mellen Press. Edited by Anthony Parel.
    To underscore the moral crisis that plagues liberal democracy, the author seeks answers by drawing from both Western and Asian thought in this outstanding analysis in political ethics. Starting with Gamwell's theory, which is grounded on God and offers a common goal for political community and establishes a firm ground for morality and political ethics the author advances and reformulates Gamwell's theory, using the insights and resources provided by Gandhi bringing a global dimension to this original critique.
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  35.  5
    'Black Lives Matter': Moral Frames for Understanding the Police Killings of Black Males.Lawrence Blum - 2020 - In Amalia Amaya & Maksymilian Del Mar (eds.), Virtue, Emotion and Imagination in Law and Legal Reasoning. Chicago: Hart Publishing. pp. 121-138.
    The Black Lives Matter movement calls attention to the injustice involved in police killings of blacks and implicitly proposes that a particular emotional attitude--caring about the life of a human being not known personally to oneself--should have been, but was not, present in the police officers involves in these killings. I examine five prominent such killings, but especially Michael Brown, Eric Garner, and Tamir Rice [the article was written before the killing of George Floyd] for the character of the moral (...)
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  36. I'm glad you asked me that question.Lawrence Zalcam - 1988 - Analysis 48 (3):160.
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  37.  2
    I'm glad you asked me that question.Lawrence Zalcman - 1988 - Analysis 48 (3):160-160.
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  38. The Ethics of Inquiry, Scientific Belief, and Public Discourse.Lawrence Torcello - 2011 - Public Affairs Quarterly 25 (3):197-215.
    The scientific consensus regarding anthropogenic climate change is firmly established yet climate change denialism, a species of what I call pseudoskepticism, is on the rise in industrial nations most responsible for climate change. Such denialism suggests the need for a robust ethics of inquiry and public discourse. In this paper I argue: (1) that ethical obligations of inquiry extend to every voting citizen insofar as citizens are bound together as a political body. (2) It is morally condemnable for public officials (...)
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  39. The Ontological Status of Cartesian Natures.Lawrence Nolan - 1997 - Pacific Philosophical Quarterly 78 (2):169–194.
    In the Fifth Meditation, Descartes makes a remarkable claim about the ontological status of geometrical figures. He asserts that an object such as a triangle has a 'true and immutable nature' that does not depend on the mind, yet has being even if there are no triangles existing in the world. This statement has led many commentators to assume that Descartes is a Platonist regarding essences and in the philosophy of mathematics. One problem with this seemingly natural reading is that (...)
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  40.  13
    The Fragile "We": Ethical Implications of Heidegger's Being and Time.Lawrence Vogel - 1994 - Evanston, Ill.: Northwestern University Press.
    Critics have charged that Heidegger's account of authenticity is morally nihilistic, that his fundamental ontology is either egocentric or chauvinistic; and many see Heidegger's turn to Nazism in 1933 as following logically from an indifference, and even hostility, to "otherness" in the premises of his early philosophy. In_ The Fragile "We": Ethical Implications of Heidegger's "Being and Time,"_ Lawrence Vogel presents three interpretations of authentic existence--the existentialist, the historicist, and the cosmopolitan--each of which is a plausible version of the (...)
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  41. Fichte on Sex, Marriage, and Gender.Rory Lawrence Phillips - 2023 - British Journal for the History of Philosophy 31 (6):1168-1187.
    “I am only what I make myself to be”, Fichte tells us. In this paper, I outline Fichte’s views on sex, marriage and gender, with two aims. Firstly, to elucidate an aspect of his moral theory which has received little attention, and secondly to argue that Fichte’s distinctive stance on selfhood, freedom, and normativity lead to a revisionary account of gender expression and identity, where people can freely carve out their own identity, irrespective of “nature”. In this paper, I therefore (...)
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  42.  31
    The East Asian Family-Oriented Principle and the Concept of Autonomy.Lawrence Y. Y. Yung - 2015 - In Ruiping Fan (ed.), Family-Oriented Informed Consent: East Asian and American Perspectives. Cham: Springer Verlag. pp. 107-121.
    The East Asian family-oriented principle is defensible in theory as a shared decision making model and thus a viable alternative to individual-oriented decision making in bioethics. There are two crucial problems with the family-oriented principle, i.e., family-oriented paternalism and conflicts of interests between a patient and his family. These obstacles may appear formidable but they are not insurmountable in practice.
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  43. Intentions, motives and the doctrine of double effect.Lawrence Masek - 2010 - Philosophical Quarterly 60 (240):567-585.
    I defend the doctrine of double effect and a so-called ‘strict’ definition of intention: A intends an effect if and only if A has it as an end or believes that it is a state of affairs in the causal sequence that will result in A's end. Following Kamm's proposed ‘doctrine of triple effect’, I distinguish an intended effect from an effect that motivates an action, and show that this distinction is morally significant. I use several contrived cases as illustrations, (...)
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  44.  81
    The thalamic dynamic core theory of conscious experience.Lawrence M. Ward - 2011 - Consciousness and Cognition 20 (2):464-486.
    I propose that primary conscious awareness arises from synchronized activity in dendrites of neurons in dorsal thalamic nuclei, mediated particularly by inhibitory interactions with thalamic reticular neurons. In support, I offer four evidential pillars: consciousness is restricted to the results of cortical computations; thalamus is the common locus of action of brain injury in vegetative state and of general anesthetics; the anatomy and physiology of the thalamus imply a central role in consciousness; neural synchronization is a neural correlate of consciousness.
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  45.  83
    Events.Lawrence Brian Lombard - 1979 - Canadian Journal of Philosophy 9 (3):425 - 460.
    In this paper, I want eventually to get around to proposing a criterion of identity for events which are changes in physical objects, where events are construed as comprising a distinct metaphysical category of thing. The proposal will be preceded by a discussion of what I take to be a mistaken suggestion for such a criterion; I will do that because I think that seeing what it takes to show why that suggestion fails helps to motivate a theory about what (...)
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  46.  87
    Confronting deep moral disagreement: The president's council on bioethics, moral status, and human embryos.Lawrence J. Nelson & Michael J. Meyer - 2005 - American Journal of Bioethics 5 (6):33 – 42.
    The report of the President's Council on Bioethics, Human Cloning and Human Dignity, addresses the central ethical, political, and policy issue in human embryonic stem cell research: the moral status of extracorporeal human embryos. The Council members were in sharp disagreement on this issue and essentially failed to adequately engage and respectfully acknowledge each others' deepest moral concerns, despite their stated commitment to do so. This essay provides a detailed critique of the two extreme views on the Council (i.e., embryos (...)
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  47. The Ontological Argument as an Exercise in Cartesian Therapy.Lawrence Nolan - 2005 - Canadian Journal of Philosophy 35 (4):521 - 562.
    I argue that Descartes intended the so-called ontological "argument" as a self-validating intuition, rather than as a formal proof. The textual evidence for this view is highly compelling, but the strongest support comes from understanding Descartes's diagnosis for why God's existence is not 'immediately' self-evident to everyone and the method of analysis that he develops for making it self-evident. The larger aim of the paper is to use the ontological argument as a case study of Descartes's nonformalist theory of deduction (...)
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  48.  17
    The Ethical Community in Kant’s Pure Rational System of Religion: Comments on Rossi’s The Ethical Commonwealth in History.Lawrence Pasternack - 2021 - Philosophia 49 (5):1901-1916.
    This commentary on Rossi’s The Ethical Commonwealth in History will address three points of interpretation related to Kant’s conception of the ethical community/commonwealth. First, I will raise a number of concerns related to Rossi’s use of Kant’s concept of the highest good. Second, I will examine the relevance of the overall project of Kant’s Religion within the Boundaries of Mere Reason to his discussion of the ethical community, a matter that Rossi does not take up. Third, I will challenge the (...)
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  49.  36
    Syllogistic Logic with Cardinality Comparisons, on Infinite Sets.Lawrence S. Moss & Selçuk Topal - 2020 - Review of Symbolic Logic 13 (1):1-22.
    This article enlarges classical syllogistic logic with assertions having to do with comparisons between the sizes of sets. So it concerns a logical system whose sentences are of the following forms: Allxareyand Somexarey, There are at least as manyxasy, and There are morexthany. Herexandyrange over subsets (not elements) of a giveninfiniteset. Moreover,xandymay appear complemented (i.e., as$\bar{x}$and$\bar{y}$), with the natural meaning. We formulate a logic for our language that is based on the classical syllogistic. The main result is a soundness/completeness theorem. (...)
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  50.  62
    The Doctrine of Double Effect, Deadly Drugs, and Business Ethics.Lawrence Masek - 2000 - Business Ethics Quarterly 10 (2):483-495.
    Manuel Velasquez and F. Neil Brady apply the doctrine of double effect to business ethics and conclude that the doctrine allows a pharmaceutical company to sell a drug with potentially fatal side effects only if it also has the good effect of saving lives. This forbidsthe sale of many common products, such as automobiles and alcohol. My account preserves the virtues of the doctrine of double effectwithout making it too restrictive. I apply the doctrine to a pharmaceutical company’s decision to (...)
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