Abstract. We argue that all human beings have a special type of dignity which is the basis for (1) the obligation all of us have not to kill them, (2) the obligation to take their well-being into account when we act, and (3) even the obligation to treat them as we would have them treat us, and indeed, that all human beings are equal in fundamental dignity. We give reasons to oppose the position that only some human beings, because of (...) their possession of certain characteristics in addition to their humanity (for example, an immediately exercisable capacity for self-consciousness, or for rational deliberation), have full moral worth. What distinguishes human beings from other animals, what makes human beings persons rather than things, is their rational nature, and human beings are rational creatures by virtue of possessing natural capacities for conceptual thought, deliberation, and free choice, that is, the natural capacity to shape their own lives. (shrink)

ABSTRACT In this article, I reply to criticisms of Dean Stretton of the pro‐life argument from substantial identity. When the criterion for the right to life proposed by most proponents of the pro‐life position is rightly understood – being a person, a distinct substance of a rational nature – this position does not lead to the difficulties Stretton claims it does.

This paper considers the revolutionary developments occurring in the field of genetic mapping and the genetic identification of disease propensities. These breakthroughs are discussed relative to the ethical and economic implications for the insurance industry. Individual's privacy rights and rights to employment must be weighed against the insurers desire for better estimates of future loss costs associated with health, life and other insurances. These are in turn related to the fundamental conception of insurance as a financial intermediary versus insurance as (...) a vehicle for social policy. (shrink)

L'économie politique, qui ose se constituer en science vers le milieu du XVIIIe siècle, n'a cessé de passionner Voltaire. S'il n'est pas un théoricien de l'économie, il en est un observateur attentif et critique, et un acteur même de l'économie pratique: financier avisé, il construit, au fil de sa longue vie, l'une des grandes fortunes du royaume. Patrick Neiertz présente ici la première étude d'ensemble des idées économiques de Voltaire en analysant l'application expérimentale qu'il fait des théories de son (...) temps (Melon, Quesnay, Turgot, Adam Smith...) dans sa propre pratique de consommateur, de gestionnaire de ses biens, enfin, d'entrepreneur. Se font jour les réactions du patriarche de Ferney aux conceptualisations économiques en formation: sur les finances publiques, sur la consommation des biens superflus, sur l'agriculture, sur l'avenir de l'industrie, sur la liberté du commerce. Il entretient auprès de ses correspondants ou lecteurs ce flux d'influence à sa manière d'écrivain, faite d'érudition et d'ironie, et à sa manière d'intellectuel engagé, en faveur de la liberté de faire comme de dire. Les idées de Voltaire sur la dette publique, sur l'assiette fiscale, sur le plein emploi, et sur le rôle de l'Etat ont une singulière modernité au siècle actuel. Son autorité n'est pas seulement celle d'un philosophe des Lumières. Elle est aussi celle d'un praticien de l'économie appliquée, 'chose qui n'est pas ordinaire aux gens de lettres'. (shrink)

En Belgique, l’enseignement de la religion et de la morale est toujours organisé sur base du pacte scolaire de 1958. Or, le paysage convictionnel s’est profondément modifié, sous le double impact de la sécularisation et de l’immigration. L’idée d’une réforme s’impose de plus en plus comme une évidence, mais elle se heurte à des obstacles juridiques et politiques. Ce livre constitue un plaidoyer en faveur de l’organisation d’un cours commun d’éthique, de citoyenneté et de culture religieuse et philosophique (ECCR). Il (...) met en évidence l’impérieuse nécessité d’introduire ce cours indispensable à l’apprentissage du vivre ensemble. (shrink)

Les cinq penseurs présentés ici par Patrick Chastenet partagent le même amour de la liberté et de la nature. Trois se réclament de l'anarchisme, deux en sont proches, tous ont profondément enrichi le terreau libertaire de l'écologie politique. L'auteur s'est lié d'amitié avec Jacques Ellul, dont il est un spécialiste reconnu. Il a sympathisé avec Ivan Illich et Bernard Charbonneau avant de découvrir les oeuvres d'Élisée Reclus et de Murray Bookchin. Son livre, rigoureux et vivant, nous introduit aux pensées (...) de ces précurseurs encore trop méconnues mais dont l'actualité n'a pas fini de nous étonner"--Page 4 of cover. (shrink)

In many animal species, the early development of the embryo follows a stereotypic pattern of cell cleavage, lineage allocation and generation of tissue asymmetry leading to delineation of the body plan with three primary embryonic axes. The mammalian embryo has been regarded as an exception and primary body axes of the mouse embryo were thought to develop after implantation. However, recent findings have challenged this view. Asymmetry in the fertilised oocyte, as defined by the position of the second polar body (...) and the sperm entry point, can be correlated with the orientation of the animal–vegetal and the embryonic–abembryonic axes in the preimplantation blastocyst. Studies of the pattern of morphogenetic movement of cells and genetic activity in the peri‐implantation embryo suggest that the animal–vegetal axis of the blastocyst might presage the orientation of the anterior–posterior axis of the gastrula. This suggests that the asymmetry of the zygote that is established at fertilisation and early cleavage has a lasting impact on the delineation of body axes during embryogenesis. BioEssays 23:508–517, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

Complexe, énigmatique car radicalement novatrice, la pensée nietzschéenne donne le sentiment d'être trop dispersée pour pouvoir être saisissable. Du reste, y a-t-il un ou plusieurs Nietzsche? Celui de L'Antéchris et d'Ecce Homo est-il le même que celui de La Naissance de la tragédie? Mais complexe ne signifie pas chaotique, et l'incertitude se dissipe si l'on repère les moments où se constituent ses positions fondamentales: quand la notion de pulsion se met-elle en place? Avec quel ouvrage la théorie des valeurs apparaît-elle? (...) À quel moment la logique du sentiment de puissance est-elle identifiée? Quand la philosophie est-elle comprise comme un dire-oui? Dans quel livre la tentative de lire la réalité tout entière comme volonté de puissance se fait-elle jour? Cet ouvrage apporte une réponse à ces questions. Il caractérise l'apport des principaux textes de Nietzsche, et montre que l'évolution de sa réflexion n'est pas faite de revirements ni d'abandons de thèses au profit de thèses nouvelles, mais d'un affinement progressif au sein d'une problématique invariante: conquête d'un mode de pensée réformé dont les grandes lignes sont dessinées dès son premier livre, La Naissance de la tragédie"--Page 4 of cover. (shrink)

PurposeEven low intensity exercise bouts of at least 15 min can improve feelings of energy and reduce systolic blood pressure. However, little is known about the psychological outcomes of briefer exercise bouts, particularly for modes of exercise that are more intense than level walking, and readily available to many working adults. This study assessed the effects of a 4-min bout of stair walking on FOE and feelings of fatigue.MethodsThirty-six young adult participants were randomized to either stair walking or seated control (...) groups. All participants walked on level-ground from a laboratory to a nearby stairwell and were seated for 4 min before beginning their experimental condition. Stair-walking participants walked up and down one flight of 16 stairs at their own pace for 4 min, while control participants remained seated during that time. Participants walked back to the laboratory for post-condition assessments. Measures of blood pressure, heart rate, rated perceived exertion, and the intensity of feelings of mental energy, mental fatigue, physical energy, and physical fatigue were assessed pre-and post-condition. Separate one-way ANOVAs were conducted on change scores for all variables.ResultsThe stair climbing group experienced significant increases in heart rate [F = 13.167, p < 0.001] and RPE [F = 93.844, p < 0.001] that were not observed in the seated control group. Four minutes of self-paced stair climbing resulted in small changes and non-significant differences within and between groups in blood pressure as well as FOE and FOF.ConclusionAlthough a 4-min self-paced exercise bout can convey short-term physiological health benefits, a 4-min bout of self-paced indoor stair walking in a stairwell was insufficient to lower blood pressure or change subjective FOE and fatigue in a sample that exhibited better than typical FOE and FOF at the pre-test. (shrink)

Que reste-t-il de l'esprit du 11 janvier? Y a-t-il une alternative à la peur et aux logiques sécuritaires? La réponse est venue des manifestations qui se sont levées partout dans le monde après les attentats meurtriers. Une autre voie est possible et porte un nom bien connu mais que nous feignons d'oublier : la Fraternité. Il est temps de redonner à l'oubliée de la République toute sa force. Non, la fraternité n'est pas cette vieille cousine que, selon l'expression de Régis (...) Debrav, nul ne songe à inviter à danser. Elle est plutôt cette jeune femme passionnée et passionnante qui nous permet de construire une alternative aux logiques de guerre et de repli identitaire. Entrons dans la danse avec elle. (shrink)

Le défi climatique appelle une mutation sans précédents de nos sociétés. Au Nord comme au Sud, il faudra bouleverser les modes de vie, changer les habitudes en matière de logement, de transport et d'alimentation. Ces changements, qui n'auront de sens qu'à l'échelle planétaire, remettent en cause notre mode de développement. Comment parvenir à réduire notre consommation d'énergie et nos émissions de gaz à effet de serre tout en répondant aux besoins essentiels de chacun? Comment au Nord inventer une économie sans (...) carbone tout en préservant les grands équilibres sociaux et économiques? Comment au Sud sortir de la pauvreté sans compromettre par un surcroît d'émissions de CO2 le bien-être des générations futures? Il est impossible de surmonter de telles difficultés sans innovations en termes de politiques publiques. Ce livre dresse un état des lieux international des nouveaux instruments et politiques possibles, touchant tant la fiscalité, les normes, les investissements, que la justice sociale, qui pourraient rythmer nos vies au cours du xxiè siècle. (shrink)

Nell’articolo l’Autore s’interroga sulla complessa questione della funzione e del significato che il diritto penale deve assumere all’interno dei sistemi costituzionali, chiedendosi, innanzitutto, se sia compito delle sue norme imporre la morale dominante nel gruppo sociale oppure se esse debbano mantenere un netto distacco rispetto a quella morale e agli umori della maggioranza sociale. A tal fine vengono analizzati due importanti dibattiti filosofici, quello ottocentesco tra John Stuart Mill e James Fitzjames Stephens e quello della metà del Novecento tra (...) class='Hi'>Patrick Devlin e H.L.A. Hart. Ciò consentirà di mettere in evidenza un chiaro legame tra il moralismo giuridico sostenuto in epoche diverse dai conservatori Stephens e Devlin ed il populismo penale dei nostri giorni, tentando, al contempo, di mettere in evidenza alcune specifiche peculiarità di quest’ultimo rispetto ai populismi del passato. (shrink)

Il s'agit d'un travail consacré à Heidegger en tant que ce dernier s'est donné pour tâche de frayer le chemin menant à une pensée post-métaphysique. C'est cette pensée qui est caractérisée comme "pensée en souffrance" au double sens de pensée à venir, qui n'est pas comme telle programmable et à laquelle il s'agit seulement de se préparer, et de pensée cherchant à répondre à l'attente d'une humanité soumise à la dévastation et en recherche de salut. Françoise Dastur a salué ce (...) texte en ces termes : "Ecrit dans une langue claire et élégante, et s'appuyant sur une lecture informée et approfondie de l'oeuvre entière de Heidegger, à laquelle on sent que l'auteur a consacré de longues années de méditation, cet essai se présente comme une tentative d'appropriation personnelle de sa pensée, et comme une mise en relief de ses axes principaux.". (shrink)

We present a one per cent measurement of the cosmic distance scale from the detections of the baryon acoustic oscillations in the clustering of galaxies from the Baryon Oscillation Spectroscopic Survey, which is part of the Sloan Digital Sky Survey III. Our results come from the Data Release 11 sample, containing nearly one million galaxies and covering approximately 8500 square degrees and the redshift range 0.2 < z < 0.7. We also compare these results with those from the publicly released (...) DR9 and DR10 samples. Assuming a concordance Λ cold dark matter cosmological model, the DR11 sample covers a volume of 13 Gpc3 and is the largest region of the Universe ever surveyed at this density. We measure the correlation function and power spectrum, including density-field reconstruction of the BAO feature. The acoustic features are detected at a significance of over 7σ in both the correlation function and power spectrum. Fitting for the position of the acoustic features measures the distance relative to the sound horizon at the drag epoch, rd, which has a value of rd,fid = 149.28 Mpc in our fiducial cosmology. We find DV = at z = 0.32 and DV = at z = 0.57. At 1.0 per cent, this latter measure is the most precise distance constraint ever obtained from a galaxy survey. Separating the clustering along and transverse to the line of sight yields measurements at z = 0.57 of DA = and H =. Our measurements of the distance scale are in good agreement with previous BAO measurements and with the predictions from cosmic microwave background data for a spatially flat CDM model with a cosmological constant. © 2014 The Author Published by Oxford University Press on behalf of the Royal Astronomical Society. (shrink)

Historically, Western philosophy has struggled to accommodate, or has simply denied, the moral value of spontaneous, non-reflective action. One important exception is in the work of K.E. Løgstrup, whose phenomenological ethics involves a claim that the ‘ethical demand’ of care for the other can only be realized through spontaneous assent to ‘sovereign expressions of life’ such as trust and mercy. Løgstrup attacks Kierkegaard for devaluing spontaneous moral action, but as I argue, Kierkegaard too offers an implicit view of spontaneous moral (...) response as a regulative ideal. In attempting to articulate the model of character-formation that such an ethics requires, we can see both Løgstrup and Kierkegaard as engaging with an ancient problematic, running from Classical Daoism to medieval mysticism, of achieving spontaneity through purgation rather than edification—not building the subject up, but demolishing personality in order to become a conduit for a transcendent normativity. (shrink)

© 2017. The American Astronomical Society. All rights reserved.We present new observations of the low-mass companion to HD 984 taken with the Gemini Planet Imager as a part of the GPI Exoplanet Survey campaign. Images of HD 984 B were obtained in the J and H bands. Combined with archival epochs from 2012 and 2014, we fit the first orbit to the companion to find an 18 au orbit with a 68% confidence interval between 14 and 28 au, an eccentricity (...) of 0.18 with a 68% confidence interval between 0.05 and 0.47, and an inclination of 119°with a 68% confidence interval between 114°and 125°. To address the considerable spectral covariance in both spectra, we present a method of splitting the spectra into low and high frequencies to analyze the spectral structure at different spatial frequencies with the proper spectral noise correlation. Using the split spectra, we compare them to known spectral types using field brown dwarf and low-mass star spectra and find a best-fit match of a field gravity M6.5 ±1.5 spectral type with a corresponding temperature of K. Photometry of the companion yields a luminosity of log=2.88 ± 0.07 dex with DUSTY models. Mass estimates, again from DUSTY models, find an age-dependent mass of 34 ±1 to 95 ±4 M Jup. These results are consistent with previous measurements of the object. (shrink)

Despite their many similarities, one apparent difference between the ethics of K.E. Løgstrup and Emmanuel Levinas concerns trust: Levinas does not analyse trust as a morally significant phenomenon, whereas Løgstrup makes it a central component of his moral phenomenology. This paper argues that an analysis of Løgstrupian trust nonetheless reveals at least three important commonalities between Levinas and Løgstrup’s moral projects: an understanding of war and ethics as metaphysical opposites; an emphasis on openness to the other as something that transcends (...) the prudential order of norms and laws; and a view of the ethical as that which breaks into and disrupts the order of human instrumental calculation. (shrink)

Psychiatry is rapidly adopting digital phenotyping and artificial intelligence/machine learning tools to study mental illness based on tracking participants’ locations, online activity, phone and text message usage, heart rate, sleep, physical activity, and more. Existing ethical frameworks for return of individual research results (IRRs) are inadequate to guide researchers for when, if, and how to return this unprecedented number of potentially sensitive results about each participant’s real-world behavior. To address this gap, we convened an interdisciplinary expert working group, supported by (...) a National Institute of Mental Health grant. Building on established guidelines and the emerging norm of returning results in participant-centered research, we present a novel framework specific to the ethical, legal, and social implications of returning IRRs in digital phenotyping research. Our framework offers researchers, clinicians, and Institutional Review Boards (IRBs) urgently needed guidance, and the principles developed here in the context of psychiatry will be readily adaptable to other therapeutic areas. (shrink)

L’objectif, éminemment politique, de cet ouvrage est de proposer pour 2012 une alternative aux programmes court-termistes et consensuels qui pourraient être développés par les candidats lors de la campagne officielle pour les élections présidentielles. Il vise à offrir une perspective de long terme de ce à quoi la société pourrait ressembler d’ici trente à cinquante ans si nous prenons un véritable virage écologique et humain et si nous opérons un changement concret de paradigme. Si, ces dernières années, un grand nombre (...) d’ouvrages et de films ont dénoncé les pires crises que traverse l’humanité, si d’autres se sont évertués à mettre en lumière des alternatives, force est de constater que très peu se sont attelés à la tâche d’offrir une vision articulée, écologique et positive de l’avenir. Loin des “yaka-fokon” et des déclarations d’intention pleines de bonne volonté, cet ouvrage met en lumière des solutions qui ont fait leur preuve, à petite comme à grande échelle, dans la plupart des domaines de la société. Pour chaque thématique, une personnalité “experte”, ayant développé une vision du sujet - voire souvent conduit ou observé une expérimentation -, propose en quelques pages des voies de transition concrètes, ainsi que les moyens à disposition de tous, qu’ils soient citoyens, élus ou entrepreneurs, pour les mettre en action. Chacune de ces propositions s’appuie sur un “cas pratique” : un exemple concluant mené à l’échelle d’un territoire européen (canton, département, région...). Au-delà d’une simple compilation, ces propositions sont mises en relation comme un véritable projet de société. (shrink)

ObjectiveOverweight and obesity [body mass index ≥ 25 kg/m2] are associated with poorer prognosis among women with breast cancer, and weight gain is common during treatment. Symptoms of depression and anxiety are also highly prevalent in women with breast cancer and may be exacerbated by post-diagnosis weight gain. Altered brain function may underlie psychological distress. Thus, this secondary analysis examined the relationship between BMI, psychological health, and resting state functional connectivity among women with breast cancer.MethodsThe sample included 34 post-menopausal women (...) newly diagnosed with Stage 0-IIa breast cancer who were enrolled in a 6-month randomized controlled trial of aerobic exercise vs. usual care. At baseline prior to randomization, whole-brain analyses were conducted to evaluate the relationship between BMI and seed-to-voxel rsFC of the hippocampus and amygdala. Connectivity values from significant clusters were then extracted and examined as predictors of self-reported depression and anxiety.ResultsMean BMI was in the obese range. For both seeds examined, higher BMI was associated with lower rsFC with regions of prefrontal cortex, including ventrolateral PFC, dorsolateral PFC, and superior frontal gyrus. Hippocampal connectivity with the vlPFC was negatively correlated with self-reported anxiety.ConclusionHigher BMI was associated with lower hippocampal and amygdala connectivity to regions of PFC implicated in cognitive control and emotion regulation. BMI-related differences in hippocampal and amygdala connectivity following a recent breast cancer diagnosis may relate to future worsening of psychological functioning during treatment and remission. Additional longitudinal research exploring this hypothesis is warranted. (shrink)

Process philosophy is said by some to be the future of American philosophy. This collection of essays, ranging from studies of Whitehead to Camus and Sir Muhammad Iqbal, extends the discussion far beyond the boundaries of North America. Several of the essays are of a more systematic character. Donald Hanks analyzes the category of process as a pre-conceptual principle used to organize experience into an intelligible pattern. Andrew Reck provides an analysis of the meaning and justification of what he considers (...) to be the ten ideas or categories requisite for a system of process philosophy. Charles Schmidtke argues that process philosophy faces a fundamental decision regarding whether the character of reality as process is given as an ultimate datum or whether process philosophy structures reality in accordance with the characteristic of creative becoming. Other essays in the volume are concerned with the concept of process in the work of a variety of philosophers, some of whom are less directly in the process tradition. Ramona Cormier analyzes the relationship of the process of experience to its unchanging aspect in connection with Camus’ concern for the meaningfulness of life and the limitations of rational inquiry. Bertrand P. Helm provides a study of James’ concept of time and Patrick S. Madigan a study of the concept of space in Leibniz and Whitehead. Whitehead’s understanding of the interaction of things provides the basis for R. Kirby Godsey’s study of the categories of substance and relation in Whitehead, and Robert C. Whittemore provides an introduction to the process philosophy of Sir Muhammad Iqbal, the little known poet-philosopher and sometime student of James Ward. James Leroy Smith’s article on Whitehead and Marx is a critical comparison of their political philosophies.—E.T.L. (shrink)

La spettacolare invasione della parola “biodiversità” nelle sfere scientifiche e politiche così come nei media ha suggerito la possibile nascita di un nuovo campo d’indagine scientifica. Tuttavia, la diversità del mondo vivente è stata l’oggetto di studio della storia naturale sin dai primordi. Gli ecologi non hanno aspettato la pubblicazione di “Biodiversity” di Wilson e Peter, nel 1988, per prendere in esame la diversità delle specie all’interno degli ecosistemi e per occuparsi di questioni fondamentali come i processi di diversificazione e (...) il significato funzionale della diversità specifica. L’analisi degli articoli pubblicati a partire dagli anni Quaranta, fino al 1988, ci permette di comprendere di quali argomenti, relativi al tema della diversità, si sono occupati gli ecologi, e come le intuizioni, gli approcci teorici e la ricerca empirica abbiano interagito. La domanda che si pone è: l’invenzione della biodiversità ha promosso la ricerca? Uno sguardo alle pubblicazioni post-1988 consente di suggerire una risposta. (shrink)

THE emotive theory of ethics made its first brief and rather tentative appearance in The Meaning of Meaning by Ogden and Richards in 1922. It did not gain currency, however, nor receive anything like a complete formulation until it was adopted by Logical Positivism, and in particular by A J Ayer in Language, Truth and Logic. Ayer’s account was soon superseded by that of Charles L Stevenson, whose views were finally elaborated in Ethics and Language in 1942. This, the classic (...) statement of emotivism, is one of the great works of moral philosophy of this century, worthy to be ranked with the Principia Ethica of G E Moore. (shrink)