Based on our empirical research on global meaning in people with spinal cord injury and people with stroke, we formulated ‘inner posture’ as a concept in rehabilitation. Inner posture, as we concluded from our empirical data, refers to the way in which people bear what cannot be changed. It helps them to live with their injury. Considering that much has already been written about meaning from a variety of disciplines, the question arises whether the concept of inner posture adds something (...) new to the existing literature, or is just another name for a phenomenon that has already been described before in different terms. In this paper, we aim to investigate this and to clarify our conceptualization, by comparing the concept of inner posture with influential concepts in healthcare literature which seem to be more or less related. In the work of Puchalski regarding spirituality, Pargament regarding religion, Eliott regarding hope and Frankl regarding attitude, we found definitions and descriptions that seemed to come close to the phenomenon we refer to as inner posture. Because these concepts have various theoretical backgrounds, the comparison can help to better understand our concept of inner posture, through a process of dialogue between traditions, following Gadamer’s notion of dialogue as fusion of horizons of understanding. We conclude that inner posture differs from the other concepts in several ways. Some of these differences are more fundamental, other are partial. This suggests that we identified a new perspective on a phenomenon partially described earlier. The comparison also inspired us to slightly adjust our definition and to formulate new research questions. (shrink)

This study examines an important aspect of energy history and policy: the intertwinement of energy technologies with ideals. Ideals play an important role in energy visions and innovation pathways. Aspirations to realize technical, social, and political ideals indicate a long-term commitment in the design of energy systems, distinguishable from commitment to other abstract goals, such as values. This study offers an analytical scheme that could help to conceptualize these differences and their impact on energy policy. In the proposed model, two (...) spheres of interaction are highlighted: a material sphere in which values and technologies co-evolve, and an imaginary sphere in which ideals interact with idealized technologies. Furthermore, the relation between these two spheres can be understood in different ways. This study examines three cases that are illustrative of the different roles of ideals in the development of energy technologies and visions: (1) the evolution of safety in nuclear reactor design; (2) visions of atomic power in France; (3) the political idealization of a tidal power scheme in the Severn Estuary. Finally, the developed model implies more general insights for the development of sociotechnical systems. Amongst others, it shows why certain projects and technologies remain a political, but not a techno–economic option. (shrink)

In the social world, multiple sensory channels are used concurrently to facilitate communication. Among human and nonhuman pri- mates, faces and voices are the primary means of transmitting social signals (Adolphs, 2003; Ghazanfar and Santos, 2004). Primates recognize the correspondence between species-specific facial and vocal expressions (Massaro, 1998; Ghazanfar and Logothetis, 2003; Izumi and Kojima, 2004), and these visual and auditory channels can be integrated into unified percepts to enhance detection and discrimination. Where and how such communication signals are integrated (...) at the neural level are poorly understood. In particular, it is unclear what role “unimodal” sensory areas, such as the auditory cortex, may play. We recorded local field potential activity, the signal that best correlates with human imaging and event-related potential signals, in both the core and lateral belt regions of the auditory cortex in awake behaving rhesus monkeys while they viewed vocalizing conspecifics. We demonstrate unequivocally that the primate auditory cortex integrates facial and vocal signals through enhancement and suppression of field potentials in both the core and lateral belt regions. The majority of these multisensory responses were specific to face/voice integration, and the lateral belt region shows a greater frequency of multisensory integration than the core region. These multisensory processes in the auditory cortex likely occur via recip- rocal interactions with the superior temporal sulcus. (shrink)

We conducted an integrative data analysis to examine the hedonic character of nostalgia. We combined positive and negative affect measures from 41 experiments manipulating nostalgia. Overall, nostalgia inductions increased positive and ambivalent affect, but did not significantly alter negative affect. The magnitude of nostalgia’s effects varied markedly across different experimental inductions of the emotion. The hedonic character of nostalgia, then, depends on how the emotion is elicited and the benchmark to which it is compared. We discuss implications for theory and (...) research on nostalgia and emotions in general. (shrink)

Rosa Menkman proposed that the concept of glitch should be considered a tipping point, a momentum, that can be seized, in which the power of subjectivity and the collaborative efforts of creators and the active spectators take centre stage. This article will discuss how in the last decades the glitch as noise and techne has shifted towards glitch as precarious aesthetics and how it has become associated with decolonial and feminist modes of critique. While the glitch is still seen as (...) a material, a techne, there is a resistant aesthetics of mutiny, a tactical revolt of the material that is confronting systemic standardization, bias and institutionalization. As presented in the exhibition VJ Um Amel, Beit Um Amel (2020), the technologically induced phenomena are analogous with the crises and states of emergency in various global infrastructures, systems and information channels. (shrink)

In this article some of the presuppositions that underly the current ideas about decision making capacity, autonomy and independence are critically examined. The focus is on chronic disorders, especially on chronic physical disorders. First, it is argued that the concepts of decision making competence and autonomy, as they are usually applied to the problem of legal (in)competence in the mentally ill, need to be modified and adapted to the situation of the chronically (physically) ill. Second, it is argued that autonomy (...) and dependence must not be considered as two mutually exclusive categories. It is suggested that decision making may take on the form of a more or less conscious decision not to be involved in making all kinds of explicit and deliberate decisions. Elaborating on Agich's distinction between ideal and actual autonomy, the concept of Socratic autonomy is introduced. (shrink)

Sentences containing pronouns and indefinite noun phrases can be said toexpress open propositions, propositions which display gaps to be filled.This paper addresses the question what is the linguistic content ofthese expressions, what information they can be said to provide to ahearer, and in what sense the information of a speaker can be said tosupport their utterance. We present and motivate first order notions ofcontent, update and support. The three notions are each defined in acompositional fashion and brought together within a (...) single and coherentframework. (shrink)

The semantics of directional prepositions is investigated from the perspective of aspect. What distinguishes telic PPs (like to the house) from atelic PPs (like towards the house), taken as denoting sets of paths, is their algebraic structure: atelic PPs are cumulative, closed under the operation of concatenation, telic PPs are not. Not only does this allow for a natural and compositional account of how PPs contribute to the aspect of a sentence, but it also guides our understanding of the lexical (...) semantics of prepositions in important ways. Semantically, prepositions turn out to be quite similar to nouns and verbs. Nominal distinctions (like singular and plural, mass and count) and verbal classes (like semelfactives and degree achievements) have their prepositional counterparts. (shrink)

We approach the semantics of prepositions from the perspective of conceptual spaces. Focusing on purely spatial locative and directional prepositions, we analyze both types of prepositions in terms of polar coordinates instead of Cartesian coordinates. This makes it possible to demonstrate that the property of convexity holds quite generally in the domain of prepositions of location and direction, supporting the important role that this property plays in conceptual spaces.

What is the right thing to do? -- "You have nothing to fear if you've done nothing wrong" -- Between culpable and blameless -- Are all mistakes equal? -- Report, disclose, protect, learn -- A just culture in your organization -- The criminalization of human error -- Is criminalization bad for safety? -- Without prosecutors, there would be no crime -- Three questions for your just culture -- Why do we blame?

This article identifies the structural and conceptual aspects of a visual construction often used in advertisements to establish a metaphoric or associative relation, that is, symmetric object alignment (SOA). It offers an account of the formal ingredients of SOA, which fall into two groups: object-constitutive factors (like size, shape, and color) and object-depictment factors (like perspective, orientation, and distance from viewing point). Both factors allow us to treat SOA as a visual rhetorical scheme. We also discuss how SOA relates to (...) conceptual structure, metaphoric or otherwise. Four types of relations are distinguished, based on the way in which perceptual and conceptual characteristics interact. Finally, we discuss the way in which these characteristics relate to the processing of such visual messages. One depictment factor will be focused on in particular: one-to-one versus one-to-many alignments. An attempt is made to connect these 2 patterns to the much-discussed topic in verbal metaphor theory, object comparison versus categorization. (shrink)

In this article we describe two core ontologies of law that specify knowledge that is common to all domains of law. The first one, FOLaw describes and explains dependencies between types of knowledge in legal reasoning; the second one, LRI-Core ontology, captures the main concepts in legal information processing. Although FOLaw has shown to be of high practical value in various applied European ICT projects, its reuse is rather limited as it is rather concerned with the structure of legal reasoning (...) than with legal knowledge itself: as many other “legal core ontologies”, FOLaw is therefore rather an epistemological framework than an ontology. Therefore, we also developed LRI-Core. As we argue here that legal knowledge is based to a large extend on common-sense knowledge, LRI-Core is particularly inspired by research on abstract common-sense concepts. The main categories of LRI-Core are: physical, mental and abstract concepts. Roles cover in particular social worlds. Another special category are occurrences; terms that denote events and situations. We illustrate the use of LRI-Core with an ontology for Dutch criminal law, developed in the e-Court European project. (shrink)

For a few decades, patients with Parkinson's disease have been treated with intracerebral transplantations of fetal mesencephalic tissue. The results of open trials have been variable. Double blind, placebo-controlled studies have recently been started in order to further investigate the efficacy of this new medical technique. In this paper we challenge the need for sham surgery in neurotransplantation research on PD patients. Considerations regarding the research subjects' informed consent, therapeutic misconception, the integrity of the human body, and the assessment of (...) risks and benefits argue against sham surgery for patients with PD. Moreover, there is an alternative, less harmful mode of research that can provide the same or comparable scientific evidence. A plea is made for intrapatient research based on quantitative measurements of the patient's pre- and post-operative condition combined with similar research on a reference group of patients who have received the standard treatment. (shrink)

This article examines the structure and processing of editorial cartoons appropriating Joe Rosenthal's famous Iwo Jima photograph in view of the theory of conceptual blending (Fauconnier & Turner, 2002 Fauconnier, G. and Turner, M. 2002. The way we think: Conceptual blending and the mind's hidden complexities, New York,, NY: Basic Books. [Google Scholar]). The main claim argued is that Blending theory accounts for complex processes of meaning constructing provoked by editorial cartoons that invoke several conceptual domains to define and evaluate (...) their topic, Iwo Jima cartoons being cases in point. The second section introduces the relevant aspects of Blending theory: mental spaces and types of blending networks. The third section addresses the Iwo Jima image as one particular input space; a moral criterion to which the selected sociopolitical topic of the cartoon is compared and judged. The fourth section isolates four types of graphic operations blending the Iwo Jima image with topical entities. The fifth section demonstrates how various kinds of blends give rise to either positive or negative evaluations. The final section argues that the study's scope of application extends to any kind of multi-domain cartoon, not just those addressed in this article. (shrink)

Medicine does not usually consider the human body from an aesthetic point of view. This article explores the notion of the lived body as aesthetic object in anthropological medicine, concentrating on the views of Buytendijk and Straus on human uprightness and gracefulness. It is argued that their insights constitute a counter-balance to the way the human body is predominantly approached in medicine and medical ethics. In particular, (1) the relationship between anthropological, aesthetic and ethical norms, (2) the possible danger of (...) a naturalistic fallacy, (3) the implications for the care of disabled people and (4) the intrinsic aesthetic quality of the human body are dealt with. (shrink)

This article focuses on the power of technological mediation from the point of view of autonomist Marxism. The first part of the article discusses the theories developed on technological mediation in postphenomenology and critical theory of technology with regard to their respective power perspectives and ways of coping with relations of power embedded in technical artifacts and systems. Rather than focusing on the clashes between the hermeneutic postphenomenological approach and the dialectics of critical theory, it is argued that in both (...) the category of resistance amidst power-relations is at least similar in one regard: resistance to the power of technology is conceptualized as a reactive force. The second part of the article reads technological mediation through the lens of the antagonistic power-perspective on class struggle developed in autonomist Marxism. The outline of a provisional autonomist philosophy of technology is developed using Foucauldian dispositifs of biopower in contrast to the hermeneutic and dialectical approach. It is thus argued that resistance should here be understood in terms of practice that subverts the technically mediated circuit of production itself. (shrink)

In contrast to the well-developed analysis of British feminism's implication in the late 19th-and early 20th-century reconstruction of the British national and imperial project, research into comparable areas of Dutch history are only just emerging. Taking as its starting point several conclusions drawn from postcolonial writing in the eld of British imperialism, this article investigates an important moment in the history of Dutch feminism, the Nationale Tentoonstelling van Vrouwenarbeid, to examine Dutch feminism's complicity in the Dutch imperial project. Simultaneously, it (...) examines the appropriation by colonial reformists of a `maternalist politics' to redene that project. In so doing, the article aims to focus attention on the interaction between metropolitan and colonial discourse and the place of maternalist politics in each. Further, the article briey reects on the signicance for Indonesian women of the operation of such discourses in the colonial context. (shrink)

Being more than mere passive objects used at human will, technologies co-determine the values and structures that shape the EU agricultural system. Technologies actively shape human interpretation, human action and co-shape our moral standards and routines. It is therefore important to account for the moral significance of agricultural technologies when characterising the structures in place within EU agriculture as well as when trying to understand why a particular agricultural technology is favoured or strongly opposed. From this perspective on technology, an (...) interesting question to pose, is how, within their current use context, genetically modified crops mediate human interpretation and human practice? This technology is of particular interest, because after more than 30 years, the debate on GM crops is still profound and highly polarised within EU society. Yet, too often, this debate is devalued as being irrational or irrelevant, while we show in this article, based on a technological mediation analysis, how ethical concerns about agricultural practices have co-evolved with the technological development of GM crops. This qualifies public debate on GM crops in the EU as both legitimate and relevant, as, from this perspective on technology, it can be seen as an important way to both characterise and discuss how EU agriculture is and should be organised. Analysing technology in terms of the myriad ways in which it mediates the relationship between humans and their world, further allows us to make some suggestions about how to broaden the ongoing EU discussion beyond the current dichotomous Yes/no framing. (shrink)

Although a large number of studies have explored the main causes of gender inequality in academia, less attention has been given to the processes underlying the failure of gender equality initiatives to enhance gender representation, especially at the professorial level. We offer a critical discourse analysis of recently promulgated gender policy documents of the five Flemish universities, and demonstrate that defensive institutional work is a fundamental process underlying resistance to gender equality in the academic profession. That is, powerful organizational actors (...) resist gender change by intentionally deploying a combination of discursive strategies that legitimate what we describe as non–time-bound gender equality initiatives: The expected outcomes are undetermined in time, and they delegitimate concrete, time-bound measures that define specific outcomes against well-defined deadlines. By explicitly bringing a temporal dimension into our analysis, we argue that defensive institutional work deflects questions regarding what ought to be achieved when, and contributes to the slow pace of gender change in academia. (shrink)

Publication in the biomedical literature is important because it is the major pathway by which new concepts and discoveries are disseminated amongst scientists. In the last 30 years there has been a dramatic increase, not only in the volume of publications but in the number of authors per article as well. This paper summarizes the current literature on authorship and its proliferation in medicine. From the literature it becomes clear that for biomedical articles, the mean number of authors increased from (...) 1.7 in 1960 to 3.1 in 1990, and there are indications that this trend is even greater in clinical medicine such that single authorship almost has disappeared. Formal guidelines of who should be considered an author have been set by the International Committee of Medical Journal Editors. There are studies suggesting that not all authors on multiauthor papers fulfill these criteria. Inappropriate multiple authorship leads to dilution of authorship responsibility and unjustified citation in curriculum vitae. Recommendations regarding the prevention of inappropriate authorship are given in this paper. (shrink)

Gaston Franssen’s essay touches on important medical and literary topics: the experience of patients with unexplained somatic complaints, the importance of giving their symptoms a name or diagnosis, the verbal representation of what bothers them, or the uncertainty all parties have to live with when an underlying cause of the symptoms is missing. A diagnosis or name such as chronic fatigue syndrome can be a relief for its sufferers, as is expressed by one of the patients in the article: “I (...) wept with relief at having a name for it.” Yet CFS is but a name for something that, medically speaking, has no substance except for the patients” complaints. CFS shares this lack of objective physical signs with other... (shrink)

Periodic attacks of uncertain origin, where the clinical presentationresembles epilepsy but there is no evidence of a somatic disease, arecalled Pseudo-Epilepsy or Pseudo-Epileptic Attack Disorder (PEAD). PEADmay be called a `non-disease', i.e. a disorder on the fringes ofestablished disease patterns, because it lacks a rationalpathophysiological explanation. The first aim of this article is tocriticize the idea, common in medical science, that diseases are realentities which exist separately from the patient, waiting to bediscovered by the doctor. We argue that doctor and (...) patient construct adisease, and that the construction of the disease PEAD includes manynormative evaluations. The second aim is to provide insight into thesuffering of patients with PEAD. We focus on three aspects of thepatient, identity, autonomy and responsibility. We present somecharacteristic descriptions of (pseudo-)epileptic attacks by FjodorDostoevsky, Gustave Flaubert and Thomas Mann. We argue that diagnosingPEAD reduces a meaningful life event into an insignificant, thoughintriguing, medical phenomenon, and that the patient will not benefitfrom being diagnosed as having PEAD. (shrink)

As a member of the British Oxford Group, psychologist Richard Ryder marked the beginning of the modern animal rights and animal welfare movement in the seventies. By introducing the concept “speciesism.” Ryder contributed importantly to the expansion of this movement. Surprisingly little attention has been paid to Ryder’s moral theory, “painism”, that aims to resolve the conflict between the two predominant rival theories in animal ethics, the deontological of Tom Regan and the utilitarian of Peter Singer. First, this paper examines (...) the kernel and historical sources of Ryder’s painist theory, linking it to the work of John Rawls and Jean-Jacques Rousseau. Second, it examines Ryder’s critique of utilitarianism. It is argued that his critique of Singer’s use of the word “sentience” is unconvincing and that his critique of utilitarian aggregation as not taking a full account of the metaphysical separateness of persons, has already been countered and dealt with. Finally this paper looks at some of the counterintuitive implications of Ryder’s theory and argues that utilitarianism might have more resources for dealing with its own alleged counterintuitive implications than Ryder acknowledges. (shrink)

Turing progressions have been often used to measure the proof-theoretic strength of mathematical theories: iterate adding consistency of some weak base theory until you “hit” the target theory. Turing progressions based on n-consistency give rise to a \ proof-theoretic ordinal \ also denoted \. As such, to each theory U we can assign the sequence of corresponding \ ordinals \. We call this sequence a Turing-Taylor expansion or spectrum of a theory. In this paper, we relate Turing-Taylor expansions of sub-theories (...) of Peano Arithmetic to Ignatiev’s universal model for the closed fragment of the polymodal provability logic \. In particular, we observe that each point in the Ignatiev model can be seen as Turing-Taylor expansions of formal mathematical theories. Moreover, each sub-theory of Peano Arithmetic that allows for a Turing-Taylor expansion will define a unique point in Ignatiev’s model. (shrink)

This paper is a presentation of astatus quæstionis, to wit of the problemof the interpretability logic of all reasonablearithmetical theories.We present both the arithmetical side and themodal side of the question.Dedicated to Dick de Jongh on the occasion of his 60th birthday.

Small tandem DNA duplications in the range of 15 to 300 base‐pairs play an important role in the aetiology of human disease and contribute to genome diversity. Here, we discuss different proposed mechanisms for their occurrence and argue that this type of structural variation mainly results from mutagenic repair of chromosomal breaks. This hypothesis is supported by both bioinformatical analysis of insertions occurring in the genome of different species and disease alleles, as well as by CRISPR/Cas9‐based experimental data from different (...) model systems. Recent work points to fill‐in synthesis at double‐stranded DNA breaks with complementary sequences, regulated by end‐joining mechanisms, to account for small tandem duplications. We will review the prevalence of small tandem duplications in the population, and we will speculate on the potential sources of DNA damage that could give rise to this mutational signature. With the development of novel algorithms to analyse sequencing data, small tandem duplications are now more frequently detected in the human genome and identified as oncogenic gain‐of‐function mutations. Understanding their origin could lead to optimized treatment regimens to prevent therapy‐induced activation of oncogenes and might expose novel vulnerabilities in cancer. (shrink)