This volume introduces the major classical Arabic philosophers through substantial selections from the key works (many of which appear in translation for the first time here) in each of the fields—including logic, philosophy of science, natural philosophy, metaphysics, ethics, and politics—to which they made significant contributions. -/- An extensive Introduction situating the works within their historical, cultural, and philosophical contexts offers support to students approaching the subject for the first time, as well as to instructors with little or no formal (...) training in Arabic thought. A glossary, select bibliography, and index are also included. (shrink)

An exploratory model is presented as a heuristic to indicate how individual perceptions of corporate reputation (before joining) and corporate ethical values (after joining) generate specific individual organizational senses of fit. The paper suggests that an ethical dimension of person-organization fit may go some way in explaining superior acquisition and retention of staff by those who are attracted to specific organizations by levels of corporate social performance consonant with their ethical expectations, or who remain with them by virtue of better (...) personal ethical fits with extant organizational ethical values. Specifically, the model suggests that individual misfits that arise from ethical expectations that either exceed or fall short of perceived organizational ethical performances lead to problematic acquisition and retention behavioural outcomes. (shrink)

An exploratory model is presented as a heuristic to indicate how individual perceptions of corporate reputation (before joining) and corporate ethical values (after joining) generate specific individual organizational senses of fit. The paper suggests that an ethical dimension of person-organization fit may go some way in explaining superior acquisition and retention of staff by those who are attracted to specific organizations by levels of corporate social performance consonant with their ethical expectations, or who remain with them by virtue of better (...) personal ethical fits with extant organizational ethical values. Specifically, the model suggests that individual misfits that arise from ethical expectations that either exceed or fall short of perceived organizational ethical performances lead to problematic acquisition and retention behavioural outcomes. (shrink)

The volume includes important criticisms of Bayesian reasoning and also gives an insight into some of the points of disagreement amongst advocates of the ...

Resilience is increasingly discussed as a key concept across many fields of international policymaking from sustainable development and climate change, insecurity, conflict and terrorism to urban and rural planning, international aid provision and the prevention of and responses to natural and man-made disasters. Edited by leading academic authorities from a number of disciplines, this is the first handbook to deal with resilience as a new conceptual approach to understanding and addressing a range of interdependent global challenges. The Handbook is divided (...) into nine sections: Introduction: contested paradigms of resilience; the challenges of resilience; governing uncertainty; resilience and neoliberalism; environmental concerns and climate change adaptation; urban planning; disaster risk reduction and response; international security and insecurity; the policy and practices of international development. Highlighting how resilience-thinking is increasingly transforming international policy-making and government and institutional practices, this book will be an indispensable source of information for students, academics and the wider public interested in resilience, international relations and international security. (shrink)

The increasing application of artificial intelligence (AI) to healthcare raises both hope and ethical concerns. Some advanced machine learning methods provide accurate clinical predictions at the expense of a significant lack of explainability. Alex John London has defended that accuracy is a more important value than explainability in AI medicine. In this article, we locate the trade-off between accurate performance and explainable algorithms in the context of distributive justice. We acknowledge that accuracy is cardinal from outcome-oriented justice because it helps (...) to maximize patients’ benefits and optimizes limited resources. However, we claim that the opaqueness of the algorithmic black box and its absence of explainability threatens core commitments of procedural fairness such as accountability, avoidance of bias, and transparency. To illustrate this, we discuss liver transplantation as a case of critical medical resources in which the lack of explainability in AI-based allocation algorithms is procedurally unfair. Finally, we provide a number of ethical recommendations for when considering the use of unexplainable algorithms in the distribution of health-related resources. (shrink)

The elaborated intrusion (EI) theory of desire (Kavanagh, Andrade, & May, 2005) attributes the motivational force of cravings to cognitive elaboration, including imagery, of apparently spontaneous thoughts that intrude into awareness. We report a questionnaire study in which respondents rated a craving for food or drink. Questionnaire items derived from EI theory formed a single factor alongside factors for anticipated reward/relief, resistance, and opportunity. In a multiple regression predicting strength of craving, the first three factors accounted for 36% of the (...) variance. Opportunity did not enter the model. In a second study, the difference between individuals' strong and weak cravings to take part in a sporting activity was shown to be related to visual, auditory, and general imagery, and to anticipated reward or relief from engaging in the activity. Implications for treatment of craving-related disorders are discussed in the light of these results and of other research indicating that interference with imagery can reduce the strength of craving. (shrink)

John Rawls is widely regarded as one of the most influential philosophers of the twentieth century, and his work has permanently shaped the nature and terms of moral and political philosophy, deploying a robust and specialized vocabulary that reaches beyond philosophy to political science, economics, sociology, and law. This volume is a complete and accessible guide to Rawls' vocabulary, with over 200 alphabetical encyclopaedic entries written by the world's leading Rawls scholars. From 'basic structure' to 'burdened society', from 'Sidgwick' to (...) 'strains of commitment', and from 'Nash point' to 'natural duties', the volume covers the entirety of Rawls' central ideas and terminology, with illuminating detail and careful cross-referencing. It will be an essential resource for students and scholars of Rawls, as well as for other readers in political philosophy, ethics, political science, sociology, international relations and law. (shrink)

Volume 20, Issue 7, July 2020, Page 106-109.

This book taps the best American thinkers to answer the essential American question: How do we sustain our experiment in government of, by, and for the people? Authored by an extraordinary and politically diverse roster of public officials, scholars, and educators, these chapters describe our nation's civic education problem, assess its causes, offer an agenda for reform, and explain the high stakes at risk if we fail.

BackgroundFor over 35 years, Africa has continued to host HIV vaccine trials geared towards overturning the HIV/aids pandemic in the continent. However, the methods of sharing the vaccines, when available remain less certain. Therefore, the study aims to explore stakeholders’ perspectives in the global South, in this case, Tanzania, on how HIV vaccines ought to be fairly shared.MethodsThe study deployed a qualitative case study design. Data were collected through in-depth interviews and focus group discussions with a total of 37 purposively (...) selected participants. This included researchers, institutional review board members, a policymaker, HIV/aids advocates, and community advisory board members. The data obtained were inductively and deductively analyzed.Results Findings indicate that HIV vaccines can be shared fairly under the principles of distributive justice (contribution, need and equality). Thus, contribution-based sharing ought to be utilized upon the necessity to prioritize vaccine access or subsidized trial benefits to host communities. Need-based sharing ought to be considered for non-host communities that are at an increased risk of HIV infection. Lastly, equal-based sharing would be useful at later stages of vaccine distribution or when the aforementioned principles are deemed morally inappropriate. However, none of the benefit-sharing approaches is free of limitations and a counterbalancing sense of unfairness.ConclusionFair sharing of HIV vaccines, when available, ought to be informed by the contribution, need and equality principles of distributive justice. Countries in the global south including Tanzania are likely to be prioritized during the distribution of the HIV vaccines due to their participation in HIV vaccine trials and due to the disproportionate HIV burden evident in the region. (shrink)

Organisms and other biological entities are mistake-prone: they get things wrong. The entities of pure physics, such as atoms and inorganic molecules, do not make mistakes: they do what they do according to physical law, with no room for error except on the part of the physicist or their theory. We set out a novel framework for understanding biology and its demarcation from physics – that of mistake-making. We distinguish biological mistakes from mere failures. We then propose a rigorous definition (...) of mistakes that, although invoking the concept of function, is compatible with various views about what functions are. The definition of mistake-making is agential, since mistakes do not just happen ¬– at least in the sense analysed here – but are made. This requires, then, a notion of biological agency which we set out as a definition of the Minimal Biological Agent. The paper then considers a series of objections to the theory presented here, along with our replies. Two key features of our theory of mistakes are, first, that it is a supplement to, not a replacement for, existing general frameworks within which biology is understood and practised. Secondly, it is designed to be experimentally productive. Hence we end with a series of case studies where mistake theory can be shown to be useful in the potential generation of research questions and novel hypotheses of interest to the working biologist. (shrink)

This paper is a critical, and fairly detailed, engagement with Lyotard's account of 'postmodern' science as it is found in his _The Postmodern Condition: A Report on Knowledge_.

In this commentary, we criticize the argument that allowing euthanasia for people with disabilities is ableist. We analyze the distinction between facts and values in medical assistance in dying, the expressivist objection, and the problem of crypwashing.

Bayesian theory now incorporates a vast body of mathematical, statistical and computational techniques that are widely applied in a panoply of disciplines, from artificial intelligence to zoology. Yet Bayesians rarely agree on the basics, even on the question of what Bayesianism actually is. This book is about the basics e about the opportunities, questions and problems that face Bayesianism today.

It is a matter of contention whether or not a general explanatory framework for the biological sciences would be of scientific value, or whether it is even achievable. In this paper we suggest that both are the case, and we outline proposals for a framework capable of generating new scientific questions. Starting with one clear characteristic of biological systems – that they all have the potential to make mistakes - we aim to describe the nature of this potential and the (...) common processes that lie behind it. Given that under most circumstances biological systems function effectively, an examination of different kinds of mistake-making provides pointers to mechanisms that must exist to make failure uncommon. This in turn informs a framework for systematic enquiry, which in this paper we apply to the haemostatic system, but which we believe could be applied to any system across biology. (shrink)

Neuroethological investigations of mammalian and avian auditory systems have documented species-specific specializations for processing complex acoustic signals that could, if viewed in abstract terms, have an intriguing and striking relevance for human speech sound categorization and representation. Each species forms biologically relevant categories based on combinatorial analysis of information-bearing parameters within the complex input signal. This target article uses known neural models from the mustached bat and barn owl to develop, by analogy, a conceptualization of human processing of consonant plus (...) vowel sequences that offers a partial solution to the noninvariance dilemma the locus equations orderly output constraint”) is hypothesized based on the notion of an evolutionarily conserved auditory-processing strategy. High correlation and linearity between critical parameters in the speech signal that help to cue place of articulation categories might have evolved to satisfy a preadaptation by mammalian auditory systems for representing tightly correlated, linearly related components of acoustic signals. (shrink)

"Law week 2005 highlights." Ethos: Official Publication of the Law Society of the Australian Capital Territory, (196), pp. 33.

The most frequent criticism of the target article is the lack of clear separability of human speech data relative to neuroethological data. A rationalization for this difference was sought in the tinkered nature of such new adaptations as human speech. Basic theoretical premises were defended, and new data were presented to support a claim that speakers maintain a low-noise relationship between F2 transition onset and offset frequencies for stops in pre-vocalic positions through articulatory choices. It remains a viable and testable (...) hypothesis that the phenomenon described by the locus equation is a functional adaptation of production mechanisms to processing preferences of the auditory system. (shrink)

Trade union leaders serve dual, seemingly contradictory roles. They must command militant organizations in conflicts with employers. Simultaneously, they must be accountable and democratically responsive to their members. Few unions possess the institutions or leadership to accomplish both. This article analyzes the practices of the International Longshore and Warehouse Union, in which effective contract negotiation and an informed, active rank-and-file democracy are mutually supportive. We offer an alternative to standard accounts of union democracy. While the claims are based on a (...) detailed case study, the theoretical model and its insights hold for labor unions and organizations more broadly. (shrink)

_Tarski’s World_ is an innovative and exciting method of introducing students to the language of first-order logic. Using the courseware package, students quickly master the meanings of connectives and qualifiers and soon become fluent in the symbolic language at the core of modern logic. The program allows students to build three-dimensional worlds and then describe them in first-order logic. The program, compatible with Macintosh and PC formats, also contains a unique and effective corrective tool in the form of a game, (...) which methodically leads students back through their errors if they wrongly evaluate the sentences in the constructed worlds. A brand new feature in this revised and expanded edition is student access to Grade Grinder, an innovative Internet-based grading service that provides accurate and timely feedback to students whenever they need it. Students can submit solutions for the program’s more than 100 exercises to the Grade Grinder for assessment, and the results are returned quickly to the students and optionally to the teacher as well. A web-based interface also allows instructors to manage assignments and grades for their classes. Intended as a supplement to a standard logic text, _Tarski’s World_ is an essential tool for helping students learn the language of logic. (shrink)

The main aim of this article is to reflect on the impact of biases related to artificial intelligence (AI) systems developed to tackle issues arising from the COVID-19 pandemic, with special focus on those developed for triage and risk prediction. A secondary aim is to review assessment tools that have been developed to prevent biases in AI systems. In addition, we provide a conceptual clarification for some terms related to biases in this particular context. We focus mainly on nonracial biases (...) that may be less considered when addressing biases in AI systems in the existing literature. In the manuscript, we found that the existence of bias in AI systems used for COVID-19 can result in algorithmic justice and that the legal frameworks and strategies developed to prevent the apparition of bias have failed to adequately consider social determinants of health. Finally, we make some recommendations on how to include more diverse professional profiles in order to develop AI systems that increase the epistemic diversity needed to tackle AI biases during the COVID-19 pandemic and beyond. (shrink)

To analyze which ethically relevant biases have been identified by academic literature in artificial intelligence algorithms developed either for patient risk prediction and triage, or for contact tracing to deal with the COVID-19 pandemic. Additionally, to specifically investigate whether the role of social determinants of health have been considered in these AI developments or not. We conducted a scoping review of the literature, which covered publications from March 2020 to April 2021. ​Studies mentioning biases on AI algorithms developed for contact (...) tracing and medical triage or risk prediction regarding COVID-19 were included. From 1054 identified articles, 20 studies were finally included. We propose a typology of biases identified in the literature based on bias, limitations and other ethical issues in both areas of analysis. Results on health disparities and SDOH were classified into five categories: racial disparities, biased data, socio-economic disparities, unequal accessibility and workforce, and information communication. SDOH needs to be considered in the clinical context, where they still seem underestimated. Epidemiological conditions depend on geographic location, so the use of local data in studies to develop international solutions may increase some biases. Gender bias was not specifically addressed in the articles included. The main biases are related to data collection and management. Ethical problems related to privacy, consent, and lack of regulation have been identified in contact tracing while some bias-related health inequalities have been highlighted. There is a need for further research focusing on SDOH and these specific AI apps. (shrink)

The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

Rare copy number variants have a prominent role in the aetiology of schizophrenia and other neuropsychiatric disorders. Substantial risk for schizophrenia is conferred by large CNVs at several loci, including microdeletions at 1q21.1, 3q29, 15q13.3 and 22q11.2 and microduplication at 16p11.2. However, these CNVs collectively account for a small fraction of cases, and the relevant genes and neurobiological mechanisms are not well understood. Here we performed a large two-stage genome-wide scan of rare CNVs and report the significant association of copy (...) number gains at chromosome 7q36.3 with schizophrenia. Microduplications with variable breakpoints occurred within a 362-kilobase region and were detected in 29 of 8,290 patients versus 2 of 7,431 controls in the combined sample. All duplications overlapped or were located within 89 kilobases upstream of the vasoactive intestinal peptide receptor gene VIPR2. VIPR2 transcription and cyclic-AMP signalling were significantly increased in cultured lymphocytes from patients with microduplications of 7q36.3. These findings implicate altered vasoactive intestinal peptide signalling in the pathogenesis of schizophrenia and indicate the VPAC2 receptor as a potential target for the development of new antipsychotic drugs. © 2011 Macmillan Publishers Limited. All rights reserved. (shrink)

‘Internalism’ is used in metaethics for a cluster of claims which bear a family resemblance. They tend to link, in some distinctive way—typically modal, mereological, or causal—different parts of the normative realm, or the normative and the psychological. The thesis of this paper is that much metaethical mischief has resulted from philosophers’ neglect of the distinction between two different features of such claims. The first is the modality of the entire claim. The second is the relation between the items specified (...) in the claim. In part one I explain this distinction and the problems neglecting it may cause. In part two I show that it has been neglected, and has caused those problems, at least with respect to one version of internalism. That is judgment internalism, which claims that moral beliefs are necessarily related to pro- or con-attitudes; e.g., that if you believe you ought to x you must have some motivation to x. The considerations standardly adduced in favor of judgment internalism support only a version which lacks the metaethical implications typically attributed to it, at least so far as anyone has shown. Proponents and opponents of judgment internalism fail to realize this because of their neglect of the modality/relation distinction. I illustrate by considering discussions of judgment internalism by Russ Shafer-Landau, Simon Blackburn, James Dreier, David Brink, and others. (shrink)

Heterogeneity within MDD has hampered identification of biological markers (e.g., intermediate phenotypes, IPs) that might increase risk for the disorder or reflect closer links to the genes underlying the disease process. The newer characterizations of dimensions of MDD within Research Domain Criteria (RDoC) domains may align well with the goal of defining IPs. We compare a sample of 25 individuals with MDD compared to 29 age and education matched controls in multimodal assessment. The multimodal RDoC assessment included the primary IP (...) biomarker, positron emission tomography (PET) with a selective radiotracer for 5-HT1A ([11C]WAY-100635), as well as event-related functional MRI with a Go/No-go task targeting the Cognitive Control network, neuropsychological assessment of affective perception, negative memory bias and Cognitive Control domains. There was also an exploratory genetic analysis with the serotonin transporter (5-HTTLPR) and monamine oxidase A (MAO-A) genes. In regression analyses, lower 5-HT1A binding potential (BP) in the MDD group was related to diminished engagement of the Cognitive Control network, slowed resolution of interfering cognitive stimuli, one element of Cognitive Control. In contrast, higher/normative levels of 5-HT1A BP in MDD (only) was related to a substantial memory bias toward negative information, but intact resolution of interfering cognitive stimuli and greater engagement of Cognitive Control circuitry. The serotonin transporter risk allele was associated with lower 1a BP and the corresponding imaging and cognitive IPs in MDD. Lowered 5HT 1a BP was present in half of the MDD group relative to the control group. Lowered 5HT 1a BP may represent a subtype including decreased engagement of Cognitive Control network and impaired resolution of interfering cognitive stimuli. Future investigations might link lowered 1a BP to neurobiological pathways and markers, as well as probing subtype-specific treatment targets. (shrink)

The moral psychology of sympathy is the linchpin of the sentimentalist moral theories of both David Hume and Adam Smith. In this paper, I attempt to diagnose the critical differences between Hume's and Smith's respective accounts of sympathy in order to argue that Smithian sympathy is more properly suited to serve as a basis for impartial moral evaluations and judgments than is Humean sympathy. By way of arguing this claim, I take up the problem of overcoming sympathetic partiality in (...) the construction of a moral point of view, acknowledged by both writers, as my primary platform. My contention is that Humean sympathy is too mechanistic to actually deliver an impartial adjudicatory perspective, and that Smithian sympathy, with its evaluative, imaginative components, succeeds where Hume's account falls short. The paper is comprised of six sections: (i) introductory remarks, (ii) a discussion of Humean sympathy, (iii) a discussion of Smithian sympathy and its distinctness, (iv) a critical analysis of Hume's attempt to correct for sympathetic partiality in the construction of the judicial spectator's general point of view, (v) a critical discussion of sympathetic partiality in Smithian sympathy & (vi) a critical analysis of Smith's construction of the impartial spectator perspective as a moral point of view. (shrink)

In this paper I explore informationalism, a pragmatic theory of modality that seems to solve some serious problems in the familiar possible worlds accounts of modality. I view the theory as an elaboration of Stalnaker's moderate modal realism, though it also derives from Dretske's semantic theory of information. Informationalism is presented in Section 2 after the prerequisite stage setting in Section 1. Some applications are sketched in Section 3. Finally, a mathematical model of the theory is developed in Section 4.How (...) many times have I said to you that when you have eliminated the impossible, whatever remains, however improbable, must be the truth? (Arthur Conan Doyle)You've put me in an impossible situation. (Anonymous)[N]othing we imagine is absolutely impossible. (David Hume). (shrink)

We argue that David Lewis’s principal principle implies a version of the principle of indifference. The same is true for similar principles that need to appeal to the concept of admissibility. Such principles are thus in accord with objective Bayesianism, but in tension with subjective Bayesianism. 1 The Argument2 Some Objections Met.