The heterogeneity of transcranial direct current stimulation protocols and clinical profiles may explain variable results in modulating excitability in the motor cortex after stroke. However, the cortical electrical effects induced by different tDCS protocols remain unclear. Here, we aimed to compare rhythm changes in electroencephalography induced by three tDCS position protocols and the association between tDCS effects and clinical factors in stroke. Nineteen patients with chronic ischemic stroke underwent four experimental sessions with three tDCS protocols [anodal, cathodal, and bilateral ] (...) and a sham protocol, according to a single-blind randomized crossover design. Resting-state EEG was acquired before and after each protocol. First, a paired-sample t-test was used to examine the difference in spectral power between pre- and post-stimulation. Then, linear and quadratic regression models were used separately to describe the association between the clinical factors of stroke and changes in spectral power which was significantly different between pre- and post-tDCS. Finally, repeated measures analysis of variance with lesion hemisphere, stimulation protocol, and the location was performed to investigate the effects of tDCS over time. The induced effect of tDCS was mainly reflected in the alpha rhythms. The alpha power was increased by atDCS, especially low-alpha, in localized areas of the central and distant areas of the frontal and parietal lobes. Bi-tDCS also affected alpha power but in a smaller area that mainly focused on high-alpha rhythms. However, ctDCS and sham had no significant effects on any EEG rhythm. The clinical factors of time since stroke and motor impairment level were related to the change in high-alpha induced by atDCS and bi-tDCS following quadratic regression models. The above-mentioned modulation effect lasted for 20 min without attenuation. In conclusion, our findings provide evidence that the alpha rhythm of EEG is modulated differently by different tDCS protocols and that high alpha is affected by clinical characteristics such as post-stroke time and motor deficits, which is of great significance for understanding the modulation effect of different tDCS protocols on stroke and the guidance of protocols to promote motor recovery following stroke. (shrink)

This article provides a method for estimating the bounds of transaction costs in horizontal mergers. Consider, for example, a completed monopoly merger in linear Cournot oligopolies with 10 symmetric firms. The method shows that its transaction costs are at most 25% (78%) of total premerger profits if there is zero (100%) excess capacity. Such estimations can be extended in a straightforward manner to other mergers and other oligopoly models. The estimation is based both on the profitability precondition, and on the (...) non-empty core precondition, which postulates that the split of a merger’s profits be in its core. The article shows that the core in linear Cournot oligopolies has a non-empty interior, and indicates that the non-empty core precondition also sheds new lights on understanding important issues such as the stylized fact that mergers are likely to occur in markets plagued by excess capacities; why profitable mergers might not be formed; and why completed mergers might break up in the future. (shrink)

China is located in the intersection area of two seismic zones. Due to this special geographical location, earthquake disasters occur frequently in China. Earthquake emergency rescue work is one of the key construction works of disaster prevention and mitigation in China. This paper mainly studies the earthquake disaster rescue model based on the complex adaptive system theory and establishes the earthquake disaster rescue model by analyzing the complex adaptive system theory and combining the earthquake rescue process. In this paper, through (...) the task allocation mechanism task, the disaster rescue task is divided into simple task and complex task, and the executive task subject is divided into single task subject and multitask subject. On the basis of considering the shortest emergency rescue time goal and the goal of maximizing the deployment utility of rescue team, the reasonable deployment of a rescue team is realized through a complex adaptive system, that is, the deployment utility of the rescue team is maximized. In this paper, the simulation experiment and comparison of the earthquake disaster rescue model based on the complex adaptive system theory are carried out. The experimental results show that the model used in this paper is better than the other two models in terms of algorithm convergence, rescue number, and overall score; in different scenarios, the relative survival probability of the model in this paper is 58.92%, 67.85%, and 77.46%, and the proportion of the wounded rescued is 66.31%, 76.45%, and 83.06%, which were higher than those of the other two models. The earthquake disaster rescue model based on the complex adaptive system theory proposed in this paper provides an effective theoretical basis and method system for postdisaster emergency rescue decision making and enhances and improves the emergency response ability to deal with large-scale geological disaster events. (shrink)

This volume aims to clarify the epistemic potential of applying evolutionary thinking outside biology, and provides a survey of the current state of the art in research on relevant topics in the life sciences, the philosophy of science, and the various areas of evolutionary research outside the life sciences. By bringing together chapters by evolutionary biologists, systematic biologists, philosophers of biology, philosophers of social science, complex systems modelers, psychologists, anthropologists, economists, linguists, historians, and educators, the volume examines evolutionary thinking within (...) and outside the life sciences from a multidisciplinary perspective. While the chapters written by biologists and philosophers of science address theoretical aspects of the guiding questions and aims of the volume, the chapters written by researchers from the other areas approach them from the perspective of applying evolutionary thinking to non-biological phenomena. Taken together, the chapters in this volume do not only show how evolutionary thinking can be fruitfully applied in various areas of investigation, but also highlight numerous open problems, unanswered questions, and issues on which more clarity is needed. As such, the volume can serve as a starting point for future research on the application of evolutionary thinking across disciplines. (shrink)

Ontology as presented in the Advaita works of Vācaspatimiśra, fl. 976-1000, Hindu philosopher.

"El libro que publicamos hoy no tiene otro fin que servir de guía a los espíritus deseosos de profundizar los problemas generales del Derecho; es una “Introducción” en el sentido más exacto del término. Se trata de orientar progresivamente al lector partiendo de las realidades más simples para llevarlo después hasta los problemas más abstractos. Hemos renunciado deliberadamente a dar a los primeros capítulos un rigor científico. Igualmente, hemos evitado de pronto los términos técnicos, esforzándonos por explicarlos y hacerlos asimilar (...) gradualmente en el curso de la obra". Claude Du Pasquier. (shrink)

The Great Synthesis of Wang Yangming Neo-Confucianism in Korea, a pioneering study of Chŏng Chedu (Hagok, 1649-1736) and Korean Yangming Neo-Confucianism, includes an annotated translation of the Chonŏn, Hagok's most important work on self-cultivation, and a comprehensive introduction to his life, scholarship, and thought.

It has often been claimed that without drastic conceptual innovations a genuine explanation of quantum interference effects and quantum randomness is impossible. This book concerns Bohmian mechanics, a simple particle theory that is a counterexample to such claims. The gentle introduction and other contributions collected here show how the phenomena of non-relativistic quantum mechanics, from Heisenberg's uncertainty principle to non-commuting observables, emerge from the Bohmian motion of particles, the natural particle motion associated with Schrödinger's equation. This book will be of (...) value to all students and researchers in physics with an interest in the meaning of quantum theory as well as to philosophers of science. (shrink)

Vincent du Bois est sculpteur sur pierre. Il a appris à tailler le marbre au pied des carrières de Carrare. Mais sa passion pour Michel-Ange ne l'empêche pas de se définir comme un artiste contemporain. De nos jours, le corps à corps avec la matière n'est plus une étape indispensable pour que l'oeuvre prenne forme. Le sculpteur peut programmer une machine pour se charger de ce travail. En tant qu'artiste, mais aussi en tant que penseur et citoyen, Vincent du Bois (...) interroge cette virtualisation de notre société qui contourne le rapport direct avec la matière et le sens du touché en donnant les pleins pouvoirs à la vue.0Il nous montre comment la révolution numérique, phénomène unique par son ampleur dans l'histoire humaine, signe le triomphe de l'abstraction sur la sensation. Vincent du Bois écrit en sculpteur. Il creuse l'essence des choses comme on taille un bloc, procédant par épanelages successifs jusqu'à ce que se révèle la forme sous-jacente. Elle prend ici les traits d'une question : quel pourra être le rôle du corps dans une société vouée aux écrans? (shrink)

Science is king. Every week, headlines announce new breakthroughs in our understanding of the universe, new technologies that will transform our environment, new medical advances that will extend our lives. Science is giving us unprecedented insight into some of the big questions that have challenged humanity ever since we've been able to formulate those questions. Where did we come from? What is the ultimate destiny of the universe? What are the building blocks of the physical world? What is consciousness? This (...) book asks us to rein in this unbridled enthusiasm for the power of science. Marcus du Sautoy explores the limits of human knowledge, to probe whether there is anything we truly cannot know. (shrink)

本书全面解读知行合一理念及其创始人王阳明.书中通过讲述王阳明的辉煌传奇,剖析知行合一.在蛮荒的龙场,王阳明悟出了"圣人之道,吾性自足",即人人皆有良知.而在血腥的沙场和险恶的朝堂,让龙场悟道实际发挥作 用的,是"知行合一",即遵循内心的良知,便能达到宁静于内,无敌于外的境界.在经历了无数磨难后,王阳明不但求得了内心的安宁,而且逐渐通过"知行合一"拥有了足以改变世界的力量.凭借知行合一的强大力量,王阳 明率文吏弱卒,荡平了江西数十年巨寇;以几封书信,一场火攻,三十五天内平定了宁王之乱;从根本上扫清了困扰明政府多年的广西部族匪患.