Myelin oligodendrocyte glycoprotein antibody-associated disease is an immune-mediated demyelinating disease of the central nervous system that is present in both adults and children. The most common clinical manifestations are optic neuritis, myelitis, acute disseminated encephalomyelitis, and brainstem syndrome. Cerebral cortical encephalitis is a rare clinical phenotype of myelin oligodendrocyte glycoprotein antibody-associated disease, which usually begins with seizures, headaches, and fever, and may be misdiagnosed as viral encephalitis in the early stages. Herein, we report two typical MOG antibody -positive patients presenting (...) with CCE, both of whom presented with headache, fever, seizures, and who recovered completely after immunotherapy. In addition, we performed a systematic review of the present literature from the perspectives of population characteristics, clinical symptoms, MRI abnormalities, treatments, and prognosis. Among the patients reported in 25 articles, 33 met our inclusion criteria, with the age of onset ranging from 4 to 52 years. Most of the patients had seizures, headache, fever, and unilateral cortical lesions on brain MRI. For acute CCE, 30 patients were treated with high-dose intravenous methylprednisolone, and the symptoms of most patients were completely relieved after immunotherapy. This study reported our experience and lessons learned in the diagnosis and treatment of MOG-Ab-positive CCE and provides a systematic review of the literature to analyse this rare clinical phenotype. (shrink)

This paper investigates the vehicle platoon control problems with both velocity constraints and input saturation. Firstly, radial basis function neural networks are employed to approximate the unknown driving resistance of a vehicle’s dynamic model. Then, a bidirectional topology, where vehicles can only communicate with their direct preceding and following neighbors, is used to depict the relationship among the vehicles in the platoon. On this basis, a neural adaptive sliding-mode control algorithm with an anti-windup compensation technique is proposed to maintain the (...) vehicle platoon with desired distance. Moreover, the string stability and the strong string stability of the whole vehicle platoon are proven through the stability theorem. Finally, numerical simulations verify the feasibility and effectiveness of the proposed control method. (shrink)

Although big data analytics capability leads to competitive performance, the mechanism of the relationship is still unclear. To narrow the research gap, this paper investigates the mediating roles of two forms of resource integration in the relationship between two forms of BDAC [big data analytics management capability and BDA technology capability] and competitive performance. Supported by Partial Least Squares-Structural Equation Modeling and the cross-sectional survey data from 219 Chinese enterprises, the results show that the resource bricolage plays a significantly mediating (...) role in the relationships between BDA management capability and competitive performance as well as in the relationship between BDA technology capability and competitive performance. Furthermore, the mediating effect in the former relationship is stronger than that in the latter relationship. Additionally, BDA technology capability only has a direct effect on resource bricolage, while BDA management capability has a stronger effect on resource optimization than that on resource bricolage. Finally, resource bricolage has a stronger impact on competitive performance than resource optimization. These findings contribute to understanding how enterprises could apply different forms of BDAC to other kinds of resource integration to achieve outstanding competitive performance. (shrink)

Although lean search is seen as an important action in lean startup, previous studies have less knowledge on how to realize it, especially in the face of traditional plans that cannot cope with sudden changes in the environment. To fill the research gap, this study investigates the effects of improvisation on lean search. Meanwhile, this research also discusses the moderating effects of entrepreneurial team heterogeneity and the environmental uncertainty to identify the boundary conditions of this relationship. Supported by the cross-sectional (...) data from 203 Chinese startups, the results show that explorative and ambidextrous improvisation are positively associated with lean search. However, the effect of exploitative improvisation on lean search is unsupported. Additionally, technology uncertainty positively moderates the relationship between exploitative improvisation and lean search. Market uncertainty positively moderates the relationship between explorative improvisation and lean search. However, the entrepreneurial team heterogeneity negatively moderates the relationship between ambidextrous improvisation and lean search. These findings contribute to understanding how startups could conduct lean search in a rapidly changing environment, which provides theoretical guidance for improving the success rate of startups. (shrink)

Researches on science and social system theory.

全书分为“科教兴国”、“走向世界”、“弘扬科智”、“控制论与人口”、“断代工程”以及“师师仰贤”六个部分,共收入作品80余篇。.

In nature, gregarious animals, insects, or bacteria usually exhibit paradoxical behaviors in the form of group fission and fusion, which exerts an important influence on group’s pattern formation, information transfer, and epidemiology. However, the fission-fusion dynamics have received little attention compared to other flocking behavior. In this paper, an intermittent selective interaction based control algorithm for the self-organized fission-fusion behavior of flocking system is proposed, which bridges the gap between the two conflicting behaviors in a unified fashion. Specifically, a hybrid (...) velocity coordination strategy that includes both the egalitarian and selective interactions is proposed, where the egalitarian interaction is to maintain the flock’s order and achieve the fusion behavior while the selective interaction strategy is for the response to external stimulus information and generates the fission behavior. Numerical simulations demonstrate that the proposed control algorithm can realize the self-organized fission-fusion behavior of flocking system under a unified framework. The influences of the main control parameters on the performance of the fission-fusion behavior are also discussed. In particular, the trade-off parameterαbalances the exploration and exploitation behaviors of flocking system and significantly enhances its movement flexibility and environmental adaptivity. (shrink)