Fecal microbiota transplantation has demonstrated efficacy and is increasingly being used in the treatment of patients with recurrent Clostridium difficile infection. Despite a lack of high-quality trials to provide more information on the long-term effects of FMT, there has been great enthusiasm about the potential for expanding its applications. However, FMT presents many serious ethical and social challenges that must be addressed as part of a successful regulatory policy response. In this article, we draw on a sample of the scientific (...) and bioethics literatures to examine clusters of ethical and social issues arising in five main areas: informed consent and the vulnerability of patients; determining what a “suitable healthy donor” is; safety and risk; commercialization and potential exploitation of vulnerable patients; and public health implications. We find that these issues are complex and worthy of careful consideration by health care professionals. Desperation of a patient should not be the basis for selecting treatment with FMT, and the patient's interests should always be of paramount concern. Authorities must prioritize development of appropriate and effective regulation of FMT to safeguard patients and donors, promote further research into safety and efficacy, and avoid abuse of the treatment. (shrink)

We prove that RCA₀ + RT $RT\begin{array}{*{20}{c}} 2 \\ 2 \\ \end{array} $ ̸͢ WKL₀ by showing that for any set C not of PA-degree and any set A, there exists an infinite subset G of A or ̅Α, such that G ⊕ C is also not of PA-degree.

Objective: Based on the theory of perceived organizational support (POS), conservation of resource (COR) and job demands-resources (JD-R) model, this study establishes a moderated mediation model to test the role of job satisfaction in mediating the relationship between perceived organizational support and job burnout, as well as the role of regulatory emotional self-efficacy in moderating the above mediating process. Method: A total of 784 police officers were surveyed with the Perceived Organizational Support Scale, the Job Burnout Questionnaire, the Regulatory Emotional (...) Self-Efficacy Scale, and the Minnesota Job Satisfaction Questionnaire. Results: (1) After controlling for gender, seniority, age, police classification, education, and marital status, regression analysis showed a significant negative correlation between perceived organizational support and burnout (r = -0.42, p < 0.01), and the former had a significant negative predictive effect on job burnout (β = -0.42, p < 0.001). (2) The mediating effect test shows that job satisfaction plays a partial role in mediating the relationship between perceived organizational support and job burnout. (3) Through the analysis of the moderated mediation model test, regulatory emotional self-efficacy moderates the first half of the path of “perceived organizational support → job satisfaction → job burnout". Conclusion: Perceived organizational support not only directly affects police job burnout but also indirectly affects police job burnout through job satisfaction. Regulatory emotional self-efficacy enhances the influence of organizational support on job satisfaction. This study indicates the combined effect of perceived organizational support, job satisfaction and regulatory emotional self-efficacy on job burnout and has certain guiding significance for alleviating police job burnout. Keywords: Perceived organizational support, Job burnout, Job satisfaction, Regulatory emotional self-efficacy, Moderated mediation. (shrink)

This study aimed to analyze the mediating effect of tolerance of uncertainty and trait anxiety on future self-continuity and intention to use Internet wealth management systems. A questionnaire survey was distributed online and a total of 388 participants completed questionnaire, The questionnaire included the following scales: Chinese version of the FSC, Intention to Use the Internet Wealth Management, TU, and TA. Pearson correlation was used to investigate the correlation coefficient between variables while the sequential regression method was used to analyze (...) relationship between variables. To analyze the collected data, the SPSS 26.0 was used. A two-step procedure was applied to analyze the mediation effect. Confirmatory factor analysis was conducted to test the measurement model. Afterward, the Maximum Likelihood method was used for path analysis, and the Bias-corrected Bootstrap method was used to investigate determine the estimated value and confidence interval of the mediating effect. To analyze the mediation effect, the Mplus 7.0 was used. The results showed that FSC positively predicted individuals’ Internet wealth management systems. Furthermore, TU and TA played complete serial multiple mediating roles between FSC and IUIWM. The role of TA and TU have negative impact on intention to use. This study provides a theoretical basis in personality psychology that Internet financial product suppliers can use to improve the attractiveness of their products. Product managers can subdivide users according to these personality traits to provide customized products. (shrink)

We apply to the art of calligraphy some of the semiotic concepts developed by Nelson Goodman. While this framework cannot describe everything that is interesting and valuable about specific calligraphic traditions, we argue that it can nonetheless elegantly capture some distinctive features of calligraphy and of its position among other major art forms.

A graph’s entropy is a functional one, based on both the graph itself and the distribution of probability on its vertex set. In the theory of information, graph entropy has its origins. Hex-derived networks have a variety of important applications in medication store, hardware, and system administration. In this article, we discuss hex-derived network of type 1 and 2, written as HDN 1 n and HDN 2 n, respectively of order n. We also compute some degree-based entropies such as Randić, (...) ABC, and G A entropy of HDN 1 n and HDN 2 n. (shrink)

Gender roles are anti-dichotomous and malleable social constructs that should theoretically be constructed independently from biological sex. However, it is unclear whether and how the factor of sex is related to neural mechanisms involved in social constructions of gender roles. Thus, the present study aimed to investigate sex specificity in gender role constructions and the corresponding underlying neural mechanisms. We measured gender role orientation using the Bem Sex-Role Inventory, used a voxel-based global brain connectivity method based on resting-state functional magnetic (...) resonance imaging to characterize the within-network connectivity in the brain reward network, and analyzed how the integration of the reward network is related to gender role scores between sex groups. An omnibus analysis of voxel-wise global brain connectivity values within a two-level linear mixed model revealed that in female participants, femininity scores were positively associated with integration in the posterior orbitofrontal cortex and subcallosal cortex, whereas masculinity scores were positively associated with integration in the frontal pole. By contrast, in male participants, masculinity was negatively correlated with integration in the nucleus accumbens and subcallosal cortex. For the first time, the present study revealed the sex-specific neural mechanisms underlying distinct gender roles, which elucidates the process of gender construction from the perspective of the interaction between reward sensitivity and social reinforcement. (shrink)

With the increasing attention to climate change, air pollution, and related public health issues, China’s new energy vehicles industry has developed rapidly. However, few studies investigated the evolution of interorganizational collaborative innovation networks in the sector domain of NEVs and the influence of different drivers on the establishment of innovation relationships. In this context, this paper uses the joint invention patent of Shenzhen, a low-carbon pilot city of China, to investigate the dynamics of network influencing factors. The social network analysis (...) shows that the scale of coinvention network of NEVs is constantly increasing, which is featured with diversified cooperative entities, and collaboration depth is also expanding. The empirical results from the Exponential Random Graph Model demonstrate that, with the deepening of collaborative innovation, technological upgrading caused by knowledge exchange makes organizations in the network more inclined to cognitive proximity and less dependent on geographical proximity. In addition, organizational proximity and triadic closure contribute positively to the collaborative network, with their relevance remaining nearly the same, while the impeding effect of cultural/language difference is slightly decreasing with time. (shrink)

Personal review record, as a form of personally identifiable information, refers to the past review information of a reviewer. The disclosure of reviewers’ personal information on electronic commerce websites has been found to substantially impact consumers’ perception regarding the credibility of online reviews. However, personal review record has received little attention in prior research. The current study investigated whether the disclosure of personal review record influenced consumers’ information processing and decision making by adopting event-related potentials measures, as ERPs allow for (...) a nuanced examination of the neural mechanisms that underlie cognitive processes. At the behavioral level, we found that the purchase rate was higher and that the reaction time was shorter when the review record was disclosed, indicating that the disclosed condition was more favorable to the participants. Moreover, ERPs data showed that the disclosed condition induced an attenuated N400 component and an increased LPP component relative to the undisclosed condition, suggesting that the former condition gave rise to less cognitive and emotional conflict and to more positive evaluations. Thus, by elucidating potential cognitive and neural underpinnings, this study demonstrates the positive impact of reviewers’ disclosure of personal review record on consumers’ purchase decisions. (shrink)

Endosteal stem cells are a subclass of bone marrow skeletal stem cell populations that are particularly important for rapid bone formation occurring in growth and regeneration. These stem cells are strategically located near the bone surface in a specialized microenvironment of the endosteal niche. These stem cells are abundant in young stages but eventually depleted and replaced by other stem cell types residing in a non‐endosteal perisinusoidal niche. Single‐cell molecular profiling and in vivo cell lineage analyses play key roles in (...) discovering endosteal stem cells. Importantly, endosteal stem cells can transform into bone tumor‐making cells when deleterious mutations occur in tumor suppressor genes. The emerging hypothesis is that osteoblast‐chondrocyte transitional identities confer a special subset of endosteal stromal cells with stem cell‐like properties, which may make them susceptible for tumorigenic transformation. Endosteal stem cells are likely to represent an important therapeutic target of bone diseases caused by aberrant bone formation. (shrink)

In functional magnetic resonance imaging studies, object selectivity is defined as a higher neural response to an object category than other object categories. Importantly, object selectivity is widely considered as a neural signature of a functionally-specialized area in processing its preferred object category in the human brain. However, the behavioral significance of the object selectivity remains unclear. In the present study, we used the individual differences approach to correlate participants’ face selectivity in the face-selective regions with their behavioral performance in (...) face recognition measured outside the scanner in a large sample of healthy adults. Face selectivity was defined as the z score of activation with the contrast of faces versus non-face objects, and the face recognition ability was indexed as the normalized residual of the accuracy in recognizing previously-learned faces after regressing out that for non-face objects in an old/new memory task. We found that the participants with higher face selectivity in the fusiform face area (FFA) and the occipital face area (OFA), but not in the posterior part of the superior temporal sulcus (pSTS), possessed higher face recognition ability. Importantly, the association of face selectivity in the FFA and face recognition ability cannot be accounted for by FFA response to objects or behavioral performance in object recognition, suggesting that the association is domain-specific. Finally, the association is reliable, confirmed by the replication from another independent participant group. In sum, our finding provides empirical evidence on the validity of using object selectivity as a neural signature in defining object-selective regions in the human brain. (shrink)

Understanding the neural basis of schizophrenia (SZ) is important for shedding light on the neurobiological mechanisms underlying this mental disorder. Structural and functional alterations in the anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (DLPFC), hippocampus, and medial prefrontal cortex (MPFC) have been implicated in the neurobiology of SZ. However, the effective connectivity among them in SZ remains unclear. The current study investigated how neuronal pathways involving these regions were affected in first-episode SZ using functional magnetic resonance imaging (fMRI). Forty-nine patients (...) with a first-episode of psychosis and diagnosis of SZ—according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision—were studied. Fifty healthy controls (HCs) were included for comparison. All subjects underwent resting state fMRI. We used spectral dynamic causal modeling (DCM) to estimate directed connections among the bilateral ACC, DLPFC, hippocampus, and MPFC. We characterized the differences using Bayesian parameter averaging (BPA) in addition to classical inference (t-test). In addition to common effective connectivity in these two groups, HCs displayed widespread significant connections predominantly involved in ACC not detected in SZ patients, but SZ showed few connections. Based on BPA results, SZ patients exhibited anterior cingulate cortico-prefrontal-hippocampal hyperconnectivity, as well as ACC-related and hippocampal-dorsolateral prefrontal-medial prefrontal hypoconnectivity. In summary, spectral DCM revealed the pattern of effective connectivity involving ACC in patients with first-episode SZ. This study provides a potential link between SZ and dysfunction of ACC, creating an ideal situation to associate mechanisms behind SZ with aberrant connectivity among these cognition and emotion-related regions. (shrink)

Background Caring behaviour is critical for nursing quality, and the clinical internship environment is a crucial setting for preparing nursing students for caring behaviours. Evidence about how to develop nursing students’ caring behaviour in the clinical environment is still emerging. However, the mechanism between the clinical internship environment and caring behaviour remains unclear, especially the mediating role of moral sensitivity and the moderating effect of self-efficacy. Research objective This study aimed to examine the mediating effect of moral sensitivity and the (...) moderating function of self-efficacy on the association between the clinical internship environment and caring behaviours. Research design A cross-sectional design used acceptable validity scales. The hypothesised moderated mediation model was tested in the SPSS PROCESS macro. Participants and research context This survey collected data from 504 nursing students in an internship at a teaching hospital in Changsha, China. Ethical considerations This study was pre-approved by the ethics committee of the medical school (No. E2022210). Informed consent was obtained from all students. Results The clinical internship environment ( B = 0.450, 95% CI = [0.371, 0.530]) and moral sensitivity ( B = 1.352, 95% CI = [1.090, 1.615]) had positive direct effects on nursing students' caring behaviours. Clinical internship environment also indirectly influenced students’ caring behaviours via moral sensitivity ( B = 0.161, 95% CI = [0.115, 0.206]). In addition, self-efficacy played a moderating role between the clinical internship environment and caring behaviours ( B = 0.019, 95% CI = [0.007, 0.031]), as well as the relationship between the clinical internship environment and moral sensitivity ( B = 0.006, 95% CI = [0.003, 0.010]). Conclusion Moral sensitivity mediates the effect of the clinical internship environment on caring behaviour, and self-efficacy strengthens both direct and indirect effects. This study emphasises the importance of self-efficacy in developing moral sensitivity and caring behaviours in nursing students. (shrink)

The long-periodic/infinite discrete Gabor transform is more effective than the periodic/finite one in many applications. In this paper, a fast and effective approach is presented to efficiently compute the Gabor analysis window for arbitrary given synthesis window in DGT of long-periodic/infinite sequences, in which the new orthogonality constraint between analysis window and synthesis window in DGT for long-periodic/infinite sequences is derived and proved to be equivalent to the completeness condition of the long-periodic/infinite DGT. By using the property of delta function, (...) the original orthogonality can be expressed as a certain number of linear equation sets in both the critical sampling case and the oversampling case, which can be fast and efficiently calculated by fast discrete Fourier transform. The computational complexity of the proposed approach is analyzed and compared with that of the existing canonical algorithms. The numerical results indicate that the proposed approach is efficient and fast for computing Gabor analysis window in both the critical sampling case and the oversampling case in comparison to existing algorithms. (shrink)

Current deep neural networks (DNNs) are far from being able to model the rich landscape of human visual experience. Beyond visual recognition, we explore the neural substrates of visual mental imagery and other visual experiences. Rather than shared visual representations, temporal dynamics and functional connectivity of the process are essential. Generative adversarial networks may drive future developments in simulating human visual experience.

This paper challenges the colonial reading of Thomas Hobbes’s use of America. Firstly, by analysing all the references and allusions to America in Hobbes’s writings, I claim that Hobbes simply uses America to support his central theory of the state of nature, showing the fundamental significance of a large and lasting society to our being and well-being. Secondly, I argue that Hobbes’s use of America does not serve a second purpose that is similar to Locke’s justification of English land appropriation. (...) Even extending such a Lockean colonial theme from Hobbes’s theory would fail due to Hobbes’s unique property theory. Lastly, with a more nuanced contextual analysis of Hobbes’s involvement in the Virginia Company and relevant textual analysis, I propose that Hobbes is not only not a supporter of English colonialism, but rather an opponent of the Virginia Company, imperial expansion, and colonial conquest. I am not denying the fact that later thinkers like Locke develop Hobbes’s notion of the American state of nature to justify European colonization in America. However, the received history should not be confused with Hobbes’s own writing purpose. Nor should we ignore Hobbes’s opposition to imperial expansion. (shrink)

Objectives: The corona virus disease-2019 pandemic spread globally, and we aimed to investigate the psychosocial impact on healthcare workers in China during the pandemic.Methods: In this systematic review and meta-analysis, we searched seven electronic databases for cross-sectional studies on psychosocial impact on HWs in relation to COVID-19 from January 1, 2020 to October 7, 2020. We included primary studies involving Chinese HWs during the pandemic, and data were extracted from the published articles. Our primary outcome was prevalence of anxiety, depression, (...) and stress disorders. We pooled prevalence value with their 95% confidence interval using random effect models and assessed study quality on the basis of an 11-item checklist recommended by the Agency for Healthcare Research and Quality. The study protocol was registered in PROSPERO.Results: We identified 25 articles comprising a total of 30,841 completed questionnaires and 22 studies for meta-analysis. The prevalence of anxiety, depression, and stress disorders was 34.4%, 31.1%, and 29.1% for HWs. The pooled prevalence of anxiety disorders for HWs from late January to early February was 46.4%, significantly higher than those in mid-term February and after late February. The pooled prevalence of depression disorders for HWs from late January to early February was 46.5%, significantly higher than those in mid-term February and after late February. HWs working in Hubei Province had a higher prevalence of anxiety and a lower prevalence of depression than those working in other regions. Nurses had a higher prevalence of anxiety and depression than other HWs.Conclusions: About one-third of HWs in China suffered anxiety, depression, and stress at the early epidemic of COVID-19. HWs in Hubei Province, especially nurses, had a higher prevalence of psychological disorders. During the pandemic, a negative psychological state may persist in a proportion of Chinese HWs, fluctuating with the control of the pandemic. The long-term impact should continue to be observed. Attention should be paid to HWs for their psychological impact due to the pandemic.Systematic Review Registration: The study protocol was registered with PROSPERO. (shrink)

To understand how different types of cues in vaccine education messages affect attitude toward campaign messages and vaccination intention, this study examined the impact of the presence of social norm appeals and the presence of fear appeals in coronavirus disease 2019 vaccine campaign posters on perceived communication quality and vaccination intention. A 2 × 2 × 3 within-subject factorial design experiment was conducted in China. Findings demonstrated that the presence of fear appeals in COVID-19 vaccine campaign posters elicited lower levels (...) of perceived communication quality and vaccination intention than those without fear appeals. The interactive effect of fear appeals and social norm appeals was also found to be significant. Specifically, positive-framed messages with group cues and fear appeal messages with individual cues elicited higher perceived information quality and stronger vaccination intention than other types of messages. Understanding how these cues function jointly in COVID-19 vaccine campaign messages will help public health practitioners create more effective intervention strategies. (shrink)

Traditional spatial enabled grammars lack flexibility in specifying the spatial semantics of graphs. This paper describes a new graph grammar formalism called the multigranularity Coordinate Graph Grammar (mgCGG) for spatial graphs. Based on the Coordinate Graph Grammar (CGG), the mgCGG divides coordinates into two categories, physical coordinates and grammatical coordinates, where physical coordinates are the common coordinates in the real world, and grammatical coordinates describe the restrictions on the spatial semantics. In the derivation and reduction of the mgCGG, the spatial (...) matching conditions between nodes are evaluated on the basis of the grammatical coordinates, which can be obtained by the specified granularities. By adjusting the granularities, both qualitative and quantitative analyses for spatial semantics can be obtained, including the transition states between them. In addition, a new redex searching algorithm with polynomial time complexity is designed for the mgCGG. A running example of drawing a flowchart is given to illustrate a practical application of the mgCGG. Through a detailed comparison with related spatial-enabled grammars, it is found that the mgCGG has good performance in four critical aspects—the semantics processing mechanism, fault-tolerance, redex searching algorithm, and practical application—providing a flexible yet uniform way to specify spatial graphs and building a bridge between nonspatial and spatial grammars. (shrink)

This study examines the impact of non-executive employee stock ownership plans (ESOP) on corporate environmental engagement. We show that granting ESOPs to non-executive employees promotes greater corporate ecological engagement from the perspectives of environmental protection expenditures, environmental information disclosure quality, and environmental, social, and governance (ESG) ratings. ESOPs unite members in a common interest, empowering them to put pressure on management to reduce carbon emissions, which benefits their physical wellbeing and increases their residual interest in long-term corporate wealth. Further, our (...) analysis reveals that companies investing in environmental protection forgo short-term profit as a consequence of high initial costs, while increasing long-term firm value. These positive effects are attributable to ESOP schemes with higher employee subscription rates, those granted to a larger number of non-executive employees, and those with longer validity periods of ownership, whose incentive effect is sufficiently powerful to offset the free-rider problem. In addition, the impact of ESOPs is more pronounced in companies with greater media exposure, those confronting intense labor market competition, and those in heavily polluting industries. Fundamentally, our study provides novel evidence of the incentive effect of ESOPs on corporate environmental engagement and of stakeholder dynamics driving the implementation of carbon reduction strategies. (shrink)

In late 2019, the COVID-19 pandemic began to spread over the world, causing millions of deaths. In the first few months of the pandemic, several countries prevented the spread of the pandemic successfully. By contrast, the pandemic in many other countries was not controlled well. For example, India encountered a second serious outbreak of COVID-19 from April 2021 due to the poor resistance measures implemented by the government. To figure out the effective countermeasures to the pandemic, this research proposes a (...) COVID-19 pandemic and its response system, which consists of the infection subsystem, the quarantine subsystem, and the medical subsystem. On this basis, an improved SEIR-SD model is established which is utilized to analyze the response measures to the pandemic quantitatively. This model successfully simulates the actual epidemic scenarios in Wuhan, which verifies its effectiveness. Afterward, the impact of hospital administration rate, quarantine rate, average contact number, and contact infection rate on the cumulative number of infections and deaths are analyzed by simulation. The results show that both the medical and administrative efforts, especially in the early stage of the epidemic, are significant in reducing the number of infections and shortening the epidemic period. In the medical aspect, the more stringent quarantine brings the earlier inflection point of the epidemic; more importantly, improving the treatment rate significantly reduces the scale of the epidemic. In the administrative aspect, enforcing individual protection and strict community closure can effectively cut off the transmission of the virus and curb the spread of the epidemic. Finally, this research proposes several practical suggestions in response to the COVID-19 pandemic. The main contribution of this research is that the effects of different response measures on the number of new infections daily and the cumulative number of deaths of a country or region in the COVID-19 pandemic are estimated quantitatively based on modeling and simulation. (shrink)

Is it possible for historical materialism to have a specific normative basis that allows the scientific aspects of Marx’s theory to be compatible with his political philosophy and ethics? No consensus has so far been reached on this question. The debate between the normative Marx and the non-normative Marx starts with an acknowledgement of a dichotomy between facts and value. In order to resolve this dichotomy, many studies tend to place value rather than facts at the heart of their arguments (...) – they attempt to demonstrate that Marx explored issues of justice, equality, and liberty at the normative level. However, by drawing on John R. Searle’s answer to the Humean question of ‘is’ and ‘ought’, we can adopt a different approach to the study that puts facts, rather than values, at the heart of the argument. Under this approach, Marx’s analysis of the facts of estrangement, surplus-value, and the like, does not consist of factual statements that exclude value and the scientific theories that result from them. Rather, it consists of the statement of institutional facts that contain values. In Marx’s case, a fact-sensitive normative theory is fully possible. (shrink)

The fire safety of industrial buildings has always been a great concern. An excellent evacuation indicator system can guide the personnel to escape quickly, thus reducing the casualties. In this study, we present a virtual simulation fire scene based on virtual reality to explore the impact of different colors, brightness values, and flashing frequencies on escape time in case of fire emergencies. The presented scene can help shorten the time required for evacuation in an industrial plant by identifying the escape (...) path under the fire and smoke environment and improve the escape efficiency. The results show that the green color is the most suitable color for evacuations; the escape efficiency increases with an increase in brightness, and there is no significant difference between the escape times under high and medium brightness; the evacuation time decreases with an increase in the flicker frequency. Based on these experimental results, the fire evacuation indicating system is designed. A virtual reality verification experiment is used to compare the escape efficiency of the improved design with an original factory’s indicating system. The verification results show that the improved scheme reduces the evacuation time and significantly improves the psychological stress on the evacuees. This work provides a theoretical basis for safe evacuation designs. (shrink)

The social facilitation of eating plays a significant role in influencing individuals’ eating decisions. However, how social eating cues are processed in health promotion messages is unclear. This study examined individuals’ food craving in response to social cues in images and emotional experiences, perceived threat, perceived efficacy, behavioral intentions, and motivational coactivation elicited by social eating cues in obesity prevention fear appeals. Results suggested that the presence of a group of people eating in an image facilitated food craving for the (...) presented foods. Moreover, fear appeals that presented obesity and its consequences with more social eating cues, versus individual eating cues, generated greater positive emotional responses, perceived threat severity, response and self-efficacy, and motivational coactivation indicating more attention and threat vigilance. However, these cues also generated fewer self-reported intentions to change unhealthy eating behaviors. Implications and suggestions for future research are discussed. (shrink)

The notion of superhigh computably enumerable (c.e.) degrees was first introduced by (Mohrherr in Z Math Logik Grundlag Math 32: 5–12, 1986) where she proved the existence of incomplete superhigh c.e. degrees, and high, but not superhigh, c.e. degrees. Recent research shows that the notion of superhighness is closely related to algorithmic randomness and effective measure theory. Jockusch and Mohrherr proved in (Proc Amer Math Soc 94:123–128, 1985) that the diamond lattice can be embedded into the c.e. tt-degrees preserving 0 (...) and 1 and that the two atoms can be low. In this paper, we prove that the two atoms in such embeddings can also be superhigh. (shrink)

This article studies the existence of positive periodic solutions for a class of strongly coupled differential systems. By applying the fixed point theory, several existence results are established. Our main findings generalize and complement those in the literature studies.

Background: The purpose of the current study was to assess the prevalence of sleep disturbances among Chinese people during the COVID-19 pandemic in a large national survey, analyze the relationship between sleep disturbances and mental health status, and explore the influencing factors of the relationship between sleep disturbances and mental health status.Methods: An online survey was accessed by 19,740 people throughout China from February 14 to 21, 2020. The survey included the Depression Anxiety Stress Scale-21 to measure psychological distress and (...) two questions about sleep disturbances. Logistic regression analyses and moderation analysis were performed.Results: Among the 14,505 respondents included in analyses, 3,783 reported sleep disturbances at least 3 days during the past week. Sleep disturbances increased the risk of depression, anxiety, and stress. Gender, age, education, occupation, frequency of attending to epidemic information, nervousness about supplies, receiving provisions of living necessities from the service department during the outbreak, number of correct responses to questions about the epidemic, and isolation/quarantine affected the risk of mental health problems among participants experiencing sleep disturbances. A moderation analysis found that sleep problems were more likely to affect depression, anxiety, and stress scores in men than women during the COVID-19 outbreak.Conclusion: During the COVID-19 outbreak, 26.08% people surveyed experienced sleep disturbances, and the presence of sleep disturbances was positively related to depression, anxiety, and stress, especially among front-line anti-epidemic workers, younger people, people living in isolation/quarantine, people with a college or greater education, and males. (shrink)

The remodeling of biological membranes is crucial for a vast number of cellular activities and is an inherently multiscale process in both time and space. Seminal work has provided important insights into nanometer‐scale membrane deformations, and highlighted the remarkable variation and complexity in the underlying molecular machineries and mechanisms. However, how membranes are remodeled at the micron‐scale, particularly in vivo, remains poorly understood. Here, we discuss how using regulated exocytosis of large (1.5–2.0 μm) membrane‐bound secretory granules in the salivary gland (...) of live mice as a model system, has provided evidence for the importance of the actomyosin cytoskeleton in micron‐scale membrane remodeling in physiological conditions. We highlight some of these advances, and present mechanistic hypotheses for how the various biochemical and biophysical properties of distinct actomyosin networks may drive this process. (shrink)

Sierpinski networks are networks of fractal nature having several applications in computer science, music, chemistry, and mathematics. These networks are commonly used in chaos, fractals, recursive sequences, and complex systems. In this article, we compute various connectivity polynomials such as M -polynomial, Zagreb polynomials, and forgotten polynomial of generalized Sierpinski networks S k n and recover some well-known degree-based topological indices from these. We also compute the most general Zagreb index known as α, β -Zagreb index and several other general (...) indices of similar nature for this network. Our results are the natural generalizations of already available results for particular classes of such type of networks. (shrink)

A connected graph is called Hamilton-connected if there exists a Hamiltonian path between any pair of its vertices. Determining whether a graph is Hamilton-connected is an NP-complete problem. Hamiltonian and Hamilton-connected graphs have diverse applications in computer science and electrical engineering. The detour index of a graph is defined to be the sum of lengths of detours between all the unordered pairs of vertices. The detour index has diverse applications in chemistry. Computing the detour index for a graph is also (...) an NP-complete problem. In this paper, we study the Hamilton-connectivity of convex polytopes. We construct three infinite families of convex polytopes and show that they are Hamilton-connected. An infinite family of non-Hamilton-connected convex polytopes is also constructed, which, in turn, shows that not all convex polytopes are Hamilton-connected. By using Hamilton connectivity of these families of graphs, we compute exact analytical formulas of their detour index. (shrink)

Previous studies have shown that smiling, fairness, intention and the results being openness to the proposer can influence the responses in ultimatum games respectively. But it is not clear that how the four factors might interact with each other in twos or in threes or in fours. This study examined the way that how the four factors work in resource distribution games by testing the differences between average rejection rates in different treatments. Two hundred and twenty healthy volunteers participated in (...) an intentional version of the ultimatum game(UG). The experiment used a 2×2×2×2 mixed design with "openness" as a between subjects factor and the other three as within subjects factors, and the participants were assigned as recipients. The results revealed that fairness or perceived good intention reduced the subject's average rejection rates. There was a significant interaction between facial expressions and openness. With fair offers, the average rejection rate for informed was lower than that of uninformed; but when unfair, no difference between the corresponding average rejection rates was found. The interaction effect of smiling and openness was also significant, the average rejection rate for informed offers was lower when the proposer was smiling and no rejection rate difference between uninformed offers and informed offers when no smiling. No other interaction effect was found. (shrink)

Based on the Chinese General Social Survey database, this article explores the relationship between income inequality and residents’ subjective well-being from the perspective of inequality of opportunity and inequality of effort. We find that inequality of opportunity has a negative impact on subjective well-being in China, where inequality of effort has a positive impact. Our empirical results are robust for changing the inequality indicators. In the sub-sample studies, consistent conclusions are obtained in rural areas, whereas in urban areas only inequality (...) of effort has a significant impact. The results of mechanism study show that inequality of opportunity decreases residents’ sense of fairness, and inequality of effort increases residents’ sense of fairness, thus affecting their subjective well-being. The results of this study provide a good response to the inconclusive research findings on the impact of income inequality on subjective well-being. (shrink)

ObjectiveInvestigating the mental health status of Chinese resident physicians during the 2019 new coronavirus outbreak.MethodsA cluster sampling method was adopted to collect all China-wide resident physicians during the epidemic period as the research subjects. The Symptom Checklist-90 self-rating scale was used to assess mental health using WeChat electronic questionnaires.ResultsIn total, 511 electronic questionnaires were recovered, all of which were valid. The negative psychological detection rate was 93.9%. Among the symptoms on the self-rating scale, more than half of the Chinese resident (...) physicians had mild to moderate symptoms of mental unhealthiness, and a few had asymptomatic or severe unhealthy mental states. In particular, the detection rate of abnormality was 88.3%, obsessive-compulsive symptoms was 90.4%, the sensitive interpersonal relationship was 90.6%, depression abnormality was 90.8% /511), anxiety abnormality was 88.3%, hostility abnormality was 85.3%, terror abnormality was 84.9%, paranoia abnormality was 86.9%, psychotic abnormalities was 89.0%, and abnormal sleeping and eating status was 90.8%. The scores of various psychological symptoms of pediatric resident physicians were significantly lower than those of non-pediatrics.ConclusionThe new coronavirus epidemic has a greater impact on the mental health of Chinese resident physicians. (shrink)

In this paper, we initiate the study of Ehrenfeucht–Fraïssé games for some standard finite structures. Examples of such standard structures are equivalence relations, trees, unary relation structures, Boolean algebras, and some of their natural expansions. The paper concerns the following question that we call the Ehrenfeucht–Fraïssé problem. Given nω as a parameter, and two relational structures and from one of the classes of structures mentioned above, how efficient is it to decide if Duplicator wins the n-round EF game ? We (...) provide algorithms for solving the Ehrenfeucht–Fraïssé problem for the mentioned classes of structures. The running times of all the algorithms are bounded by constants. We obtain the values of these constants as functions of n. (shrink)

The main result of this paper states that the isomorphism problem for ω-automatic trees of finite height is at least has hard as second-order arithmetic and therefore not analytical. This strengthens a recent result by Hjorth, Khoussainov, Montalbán, and Nies showing that the isomorphism problem for ω-automatic structures is not in . Moreover, assuming the continuum hypothesis CH, we can show that the isomorphism problem for ω-automatic trees of finite height is recursively equivalent with second-order arithmetic. On the way to (...) our main results, we show lower and upper bounds for the isomorphism problem for ω-automatic trees of every finite height: It is decidable , for height 1 , -hard and in for height 3, and - and -hard and in for height . All proofs are elementary and do not rely on theorems from set theory. (shrink)

During the COVID-19 pandemic, organizations need to effectively manage changes, and employees need to proactively adapt to these changes. The present research investigated when and how individual employees’ narcissism was related to their change-oriented organizational citizenship behavior. Specifically, based on a trait activation perspective, this research proposed the hypotheses that individual employees’ narcissism and environmental uncertainty would interactively influence employees’ change-oriented organizational citizenship behavior via felt responsibility for constructive change; furthermore, the effect of narcissism on change-oriented organizational citizenship behavior via (...) felt responsibility for constructive change would be stronger when the environmental uncertainty prompted by the COVID-19 pandemic was high rather than low. Two studies were conducted to test these hypotheses: an online survey of 180 employees in mainland China and a field study of 167 leader–follower dyads at two Chinese companies. The current research reveals a bright side of narcissism, which has typically been recognized as a dark personality trait, and enriches the understanding of the antecedents of change-oriented organizational citizenship behavior. This research can also guide organizations that wish to stimulate employee proactivity. (shrink)

Individuals' capacity to participate in leisure activities is contingent upon their ability to overcome obstacles. It is worthwhile to investigate how individuals perceive constraints on their leisure activities participation during the COVID-19 pandemic. This study demonstrates that the connotation of leisure constraints during pandemic includes personal health concerns, shock on economic revenue, reduced freedom of travel, and inconvenience associated with epidemic prevention. Reduced travel freedom is the most influential factor on participation intentions, followed by personal health concerns. Significant differences in (...) perceptions of constraints are observed between groups with different characteristics. (shrink)