Evidence-based medicine (EBM), the dominant approach to assessing the effectiveness of clinical and public health interventions, focuses on the results of association studies. EBM+ is a development of EBM that systematically considers mechanistic studies alongside association studies. In this paper we provide several examples of the importance of mechanistic evidence to coronavirus research. (i) Assessment of combination therapy for MERS highlights the need for systematic assessment of mechanistic evidence. (ii) That hypertension is a risk factor for severe disease in the (...) case of SARS-CoV-2 suggests that altering hypertension treatment might alleviate disease, but the mechanisms are complex, and it is essential to consider and evaluate multiple mechanistic hypotheses. (iii) To be confident that public health interventions will be effective requires a detailed assessment of social and psychological components of the mechanisms of their action, in addition to mechanisms of disease. (iv) In particular, if vaccination programmes are to be effective, they must be carefully tailored to the social context; again, mechanistic evidence is crucial. We conclude that coronavirus research is best situated within the EBM+ evaluation framework. (shrink)

The role of mechanistic evidence tends to be under-appreciated in current evidencebased medicine (EBM), which focusses on clinical studies, tending to restrict attention to randomized controlled studies (RCTs) when they are available. The EBM+ programme seeks to redress this imbalance, by suggesting methods for evaluating mechanistic studies alongside clinical studies. Drug approval is a problematic case for the view that mechanistic evidence should be taken into account, because RCTs are almost always available. Nevertheless, we argue that mechanistic evidence is central (...) to all the key tasks in the drug approval process: in drug discovery and development; assessing pharmaceutical quality; devising dosage regimens; assessing efficacy, harms, external validity, and cost-effectiveness; evaluating adherence; and extending product licences. We recommend that, when preparing for meetings in which any aspect of drug approval is to be discussed, mechanistic evidence should be systematically analysed and presented to the committee members alongside analyses of clinical studies. (shrink)

Proponents of evidence-based medicine and some philosophers of science seem to agree that knowledge of mechanisms can help solve the problem of applying results of controlled studies to target populations (‘the problem of extrapolation’). We describe the problem of extrapolation, characterize mechanisms, and outline how mechanistic knowledge might be used to solve the problem. Our main thesis is that there are four often overlooked problems with using mechanistic knowledge to solve the problem of extrapolation. First, our understanding of mechanisms is (...) often (and arguably, likely to remain) incomplete. Secondly, knowledge of mechanisms is not always applicable outside the tightly controlled laboratory conditions in which it is gained. Thirdly, mechanisms can behave paradoxically. Fourthly, as Daniel Steel points out, using mechanistic knowledge faces the problem of the ‘extrapolator’s circle’. At the same time, when the problems with mechanistic knowledge have been addressed, such knowledge can and should be used to mitigate (nothing can entirely solve) the problem of extrapolation. (shrink)

BackgroundResearch Ethics Boards, or Institutional Review Boards, protect the safety and welfare of human research participants. These bodies are responsible for providing an independent evaluation of proposed research studies, ultimately ensuring that the research does not proceed unless standards and regulations are met.Main bodyConcurrent with the growing volume of human participant research, the workload and responsibilities of Research Ethics Boards (REBs) have continued to increase. Dissatisfaction with the review process, particularly the time interval from submission to decision, is common within (...) the research community, but there has been little systematic effort to examine REB processes that may contribute to inefficiencies. We offer a model illustrating REB workflow, stakeholders, and accountabilities.ConclusionBetter understanding of the components of the research ethics review will allow performance targets to be set, problems identified, and solutions developed, ultimately improving the process. (shrink)

Publication de deux poèmes byzantins du 12ème s. attribués à Théodore Prodomos, qui fournissent un certain nombre de renseignements sur les tentes des camps d'hiver des Comnène, et en particulier sur celle de la maison d'Irène la Sevastokratorissa. Cette étude mène l'auteur à un commentaire historico-artistique des éléments décrits: il compare d'abord ceux-ci avec l'art des 11ème et et 12ème s., et particulièrement avec l'art profane, puis il s'interroge sur l'authenticité des descriptions par rapport aux figures de rhétorique employées dans (...) ces textes. (shrink)

Achieving a high quality of life is dependent upon how individuals face adversity. Positive psychological interventions are well-suited to support coping efforts; however, experimental research is limited. The purpose of the current research was to examine whether different savoring interventions could increase important coping resources in response to a social-evaluative hassle. We completed an experimental mixed subject design study with a university student sample. All participants completed a hassle induction task and were then randomly assigned into different intervention groups. Positive (...) emotion ratings were collected at three points in time. Results revealed a significant time x intervention interaction effect, such that individuals in the savoring the moment intervention reported higher levels of positive emotions compared to individuals assigned to the true control group, guided imagery control group, and savoring through reminiscence intervention. Such findings represent a significant extension to savoring theory and offer support for savoring the moment exercises as a primary prevention strategy to bolster effective responses to social-evaluative hassles. (shrink)

This chapter looks at approaches developed by philosophers of science that may be useful to those working in religion, theology, and the philosophy of religion. Philosophers of science have spent a lot of time thinking about how theories change, what to do with surprising data and conflicting explanations, and what to say when we need more categories than true and false. Sometimes, all this is hidden behind terms such as antirealism, paradigm, verisimilitude, and inference to the best explanation. The author (...) unpacks a bit of jargon from the philosophy of science and considers some analogies and applications to matters of religion. The chapter also presents some of the tools developed in the philosophy of science. Finally, it discusses what is supposed to be the fundamental divide between religion and science: the former is based on faith, while the latter is based on reason. (shrink)

The proposal that the criminal justice system should focus on rehabilitation – rather than retribution, deterrence, or expressive denunciation – is among the least popular ideas in legal philosophy. Foremost among rehabilitation’s alleged weaknesses is that it views criminals as blameless patients to be treated, rather than culpable moral agents to be held accountable. This article offers a new interpretation of the rehabilitative approach that is immune to this objection and that furnishes the moral foundation that this approach has lacked. (...) The view rests on the principle that moral agents owe it to one another to maintain the dependability of their moral capacities. Agents who culpably commit criminal wrongs, however, betray an unacceptable degree of moral unreliability. Punishment, on this theory, consists in the enforcement of the duties that offenders have to reduce their own likelihood of recidivism. (shrink)

Tonkens has issued a seemingly impossible challenge, to articulate a comprehensive ethical framework within which artificial moral agents satisfy a Kantian inspired recipe—"rational" and "free"—while also satisfying perceived prerogatives of machine ethicists to facilitate the creation of AMAs that are perfectly and not merely reliably ethical. Challenges for machine ethicists have also been presented by Anthony Beavers and Wendell Wallach. Beavers pushes for the reinvention of traditional ethics to avoid "ethical nihilism" due to the reduction of morality to mechanical causation. (...) Wallach pushes for redoubled efforts toward a comprehensive account of ethics to guide machine ethicists on the issue of artificial moral agency. Options, thus, present themselves: reinterpret traditional ethics in a way that affords a comprehensive account of moral agency inclusive of both artificial and natural agents, or give up on the possibility and “muddle through” regardless. This series of papers pursues the first option, meets Tonkens' "challenge" and pursues Wallach's ends through Beavers’ proposed means, by "landscaping" traditional moral theory in resolution of a comprehensive account of moral agency. This first paper sets out the challenge and establishes the tradition that Kant had inherited from Aristotle, briefly entertains an Aristotelian AMA, fields objections, and ends with unanswered questions. The next paper in this series responds to the challenge in Kantian terms, and argues that a Kantian AMA is not only a possibility for Machine ethics research, but a necessary one. (shrink)

The rapprochement between critical social theory and liberal political theory raises the question of whether Critical Theory remains adequately equipped to respond to contemporary global crises such as nationalism and ecological devastation. Recent Critical Theory---represented by the 2nd generation Frankfurt School writings of Jurgen Habermas and his U.S. reception---has neglected the original program of critical theory as an oppositional methodology oriented to liberation. This liberatory spirit has been replaced by an internal debate whose boundaries are set by current discourses within (...) the philosophy of language and moral/political philosophy, and by the one-sided response of Critical Theorists to the influx of postmodernism to the academy. ;Habermas's procedural framework for democratic legitimation, in which meeting formal conditions legitimates the outcome of discursively-based decisions, implies minimal background conditions which, when met by existing institutions and mechanisms of consent-generation, lead Habermas to tacitly legitimate both anti-democratic practices and geo-political calamities. This brings Habermas's theory quite close to the uncritical Enlightenment discourse of John Rawls. While Habermas argues he is the bearer of a "counter-discourse of modernity," his theory, like Rawls's excludes the margins of opposition in which hope for liberation from existing institutions is most clearly found. ;I thus recommend a return to first-generation critical theory, reread as a philosophy of praxis. I argue against recent post-Marxist social theory that the mere proliferation of discourses is inadequate to respond to the demands of liberation articulated by the disenfranchised and oppressed. I also argue against neo0Heideggerian "politics of thought." These discourses are replaced by a New Critical Theory which refuses abstract polarization between modern and postmodern thought, and seeks to displace both current discourses of legitimation and the regimes they support. New Critical Theory is exemplified by recent developments in feminist theory and postmodern social theory . ;Though ongoing pathologies of modernity resist global attempts at either remediation of radical change-and thus ope for liberation continues to appear impossible-I conclude that oppositional theory and oppositional movements have not yet exhausted all possibilities for mutual reinforcement. (shrink)

From the early 1960s until his death, French philosopher Gilles Deleuze wrote many influential works on philosophy, literature, film, and fine art. One of Deleuze's main philosophical projects was a systematic inversion of the traditional relationship between identity and difference. This Deleuzian philosophy of difference is the subject of Jeffrey A. Bell's Philosophy at the Edge of Chaos. Bell argues that Deleuze's efforts to develop a philosophy of difference are best understood by exploring both Deleuze's claim to be a (...) Spinozist, and Nietzsche's claim to have found in Spinoza an important precursor. Beginning with an analysis of these claims, Bell shows how Deleuze extends and transforms concepts at work in Spinoza and Nietzsche to produce a philosophy of difference that promotes and, in fact, exemplifies the notions of dynamic systems and complexity theory. With these concepts at work, Deleuze constructs a philosophical approach that avoids many of the difficulties that linger in other attempts to think about difference. Bell uses close readings of Plato, Aristotle, Spinoza, Nietzsche, Heidegger, Derrida, and Whitehead to illustrate how Deleuze's philosophy is successful in this regard and to demonstrate the importance of the historical tradition for Deleuze. Far from being a philosopher who turns his back on what is taken to be a mistaken metaphysical tradition, Bell argues that Deleuze is best understood as a thinker who endeavoured to continue the work of traditional metaphysics and philosophy. (shrink)

Cultural trauma occurs when members of a collectivity feel they have been subjected to a horrendous event that leaves indelible marks upon their group consciousness, marking their memories forever and changing their future identity in fundamental and irrevocable ways. While this new scientific concept clarifies causal relationships between previously unrelated events, structures, perceptions, and actions, it also illuminates a neglected domain of social responsibility and political action. By constructing cultural traumas, social groups, national societies, and sometimes even entire civilizations, not (...) only cognitively identify the existence and source of human suffering, but may also take on board some significant moral responsibility for it. Insofar as they identify the cause of trauma in a manner that assumes such moral responsibility, members of collectivities define their solidary relationships that allow them to share the suffering of others. Is the suffering of others also our own? In thinking that it might in fact be, societies expand the circle of the ‘we’ and create the possibility for repairing societies to prevent the trauma from happening again. By the same token, social groups can, and often do, refuse to recognize the existence of others’ suffering, or place the responsibility for it on people other than themselves. Empirically, this article extensively considers trauma construction in the case of the Holocaust – the mass murder of Jews by the German Nazis – but also examines trauma processes in relation to African-Americans, indigenous peoples, colonial victims of Western and Japanese imperialism, the Nanjing Massacre, and victims of the early communist regimes in Soviet Russia and Maoist China. (shrink)

This essay responds to Badiou's charge that Deleuze fails to set forth a philosophy that is “beyond Gategorical oppositions.” It is argued that this criticism of Deleuze is founded upon a misreading of the Deleuzean distinction between the virtual and the actual, a reading that carries forward Badiou's misreading of Spinoza and, hence, of Deleuze's Spinozism. With this corrected, we show how the virtual‐actual distinction operates within the experimental philosophy, or pragmatics, that Deleuze, and later Deleuze and Guattari, sets forth. (...) It is this pragmatics that is precisely the philosophy of difference that is beyond categorical oppositions. Through a comparison of Deleuzean pragmatics with the work of Hume and Peirce, we are able to respond to Badiou's further criticism that Deleuze's philosophy fails to understand the conditions for creativity in thought and culture. This criticism is itself resolved once one corrects for Badiou's misreading of Deleuze's virtual‐actual distinction. (shrink)

Françios Viète was a geometer in search of better techniques for astronomical calculation. Through his theorem on angular sections he found a use for higher-dimensional geometric magnitudes which allowed him to create an algebra for geometry. We show that unlike traditional numerical algebra, the knowns and unknowns in Viète’s logistice speciosa are the relative sizes of non-arithmetized magnitudes in which the “calculations” must respect dimension. Along with this foundational shift Viète adopted a radically new notation based in Greek geometric equalities. (...) His letters stand for values rather than types, and his given values are undetermined. Where previously algebra was founded in polynomials as aggregations, Viète became the first modern algebraist in working with polynomials built from operations, and the notations reflect these conceptions. Viète’s innovations are situated in the context of sixteenth-century practice, and we examine the interpretation of Jacob Klein, the only historian to have conducted a serious inquiry into the ontology of Viète’s “species”. (shrink)

This volume of Social Philosophy Today contains a selection of papers presented at the 30th International Social Philosophy Conference (2013), an annual event sponsored by the North American Society for Social Philosophy. The theme of the conference was "Food". This volume invites wider discussion of the issues explored at the conference, including food production, distribution, and consumption. Contributors include Susan Dielman, Erinn Gilson, Joan McGregor, José Medina, Andrew Pierce, and Sally Scholz.

MacKay and Robinson (2016) provide a critical analysis of four organ donation registration options using an expanded conception of manipulation introduced by Jennifer Blumenthal-Barby (Blumenthal-B...

Two intertwined themes run through Kant’s last, unfinished work, known to us as the Opus postumum: the comprehensibility of physics as a science and of human freedom as a causal power.1 The two themes come together in Kant’s theory of self-positing. Although the Opus postumum has received substantial attention in recent decades, there has been an insufficient focus on human embodiment (self-positing) as the bridge between nature and freedom in Kant’s final period. In this paper, I contribute to remedying this (...) defect by showing the centrality of embodiment for Kant’s motivating project of a transition from the metaphysics of natural science to the actual science of physics. Many times in the disordered manuscripts, Kant characterizes this transition in terms of a schematism conceived of as parallel to—or as an extension of—the first Critique schematism. I argue here that Kant’s theory of self-positing places human embodiment in the role of serving as this schematism and making the needed transition. (shrink)

As social theorists seek to understand the contemporary challenges of radical populism, we would do well to reconsider the febrile insights of the psychoanalytic social theorist Erich Fromm. It was Fromm who, at the beginning of the 1930s, conceptualized the emotional and sociological roots of a new ‘authoritarian character’ who was meek in the face of great power above and ruthless to the powerless below. It was Fromm, in the 1950s, who argued that societies, not only individuals, could be sick. (...) This essay traces the intertwining of psychoanalytic and sociological methods that allowed Fromm to create such new ideas. At the same time, it highlights how Fromm’s sociology was hampered by an economistic Marxist approach to the institutions and culture of democratic capitalist societies. Such theoretical restriction prevented Fromm from conceptualizing how institutions like democracy, science, and psychotherapy can provide resources for widespread emotional recuperation and civil repair. (shrink)

I argue that a strong mind–body dualism is required of any formulation of quantum mechanics that satisfies a relatively weak set of explanatory constraints. Dropping one or more of these constraints may allow one to avoid the commitment to a mind–body dualism but may also require a commitment to a physical–physical dualism that is at least as objectionable. Ultimately, it is the preferred basis problem that pushes both collapse and no-collapse theories in the direction of a strong dualism in resolving (...) the quantum measurement problem. Addressing this problem illustrates how the construction and evaluation of explanatorily rich physical theories are inextricably tied to the evaluation of traditional philosophical issues. (shrink)

The History of Beyng belongs to a series of Martin Heidegger's reflections from the 1930s that concern how to think about being not merely as a series of occurrences, but as essentially historical or fundamentally as an event. Beginning with Contributions to Philosophy, these texts are important for their meditations on the oblivion and abandonment of being, politics, and race, and for their incisive critique of power, force, and violence. Originally published in 1998 as volume 69 of Heidegger's Complete Works, (...) this English translation opens new avenues for understanding the trajectory of Heidegger's thinking during this crucial time. (shrink)

There is one critical way we honor great tragedies: by never forgetting. Collective remembrance is as old as human society itself, serving as an important source of social cohesion, yet as Jeffrey Andrew Barash shows in this book, it has served novel roles in a modern era otherwise characterized by discontinuity and dislocation. Drawing on recent theoretical explorations of collective memory, he elaborates an important new philosophical basis for it, one that unveils profound limitations to its scope in relation (...) to the historical past. Crucial to Barash’s analysis is a look at the radical transformations that symbolic configurations of collective memory have undergone with the rise of new technologies of mass communication. He provocatively demonstrates how such technologies’ capacity to simulate direct experience—especially via the image—actually makes more palpable collective memory’s limitations and the opacity of the historical past, which always lies beyond the reach of living memory. Thwarting skepticism, however, he eventually looks to literature—specifically writers such as Walter Scott, Marcel Proust, and W. G. Sebald—to uncover subtle nuances of temporality that might offer inconspicuous emblems of a past historical reality. (shrink)

Optical media were instrumental in transforming the conception of facts, objectivity, and the »real.« This paper considers their role in structuring understandings of counterfactuals and states that could not be real. By returning to Ernst Mach’s photographic ballistics experiments, writing on thought experiments (a term he coined), and his dispute with Max Planck about the nature of the Weltbild, the article shows that, despite his legacy as a positivist, Mach’s epistemology of mechanical images opened a legitimate space of indeterminacy, contingency, (...) and counterfactuality. (shrink)

Intelligent design (ID) raises several challenges for the relation between science and religion. One's views on these matters ramify across the other sciences, including physics. Can design, especially supernatural design, play any legitimate role in science? Is the ID question just a matter of evidence? What is the proper role for naturalism in all this? These are important questions in the philosophy of science. Before taking them up, this chapter briefly looks at the core concepts used in ID today. There (...) is a less visible but equally menacing problem for the viability of ID. Methodological naturalism (MN) gets a lot of attention, but there is another methodological shaping principle to be contended with, namely, conservatism. Conservatism is also the reason ID attracts so many theists and few nontheists. If one already believes in an intelligence that can play the role of designer, then ID‐based science is not a radical move. (shrink)

It is generally accepted, following Landauer and Bennett, that the process of measurement involves no minimum entropy cost, but the erasure of information in resetting the memory register of a computer to zero requires dissipating heat into the environment. This thesis has been challenged recently in a two-part article by Earman and Norton. I review some relevant observations in the thermodynamics of computation and argue that Earman and Norton are mistaken: there is in principle no entropy cost to the acquisition (...) of information, but the destruction of information does involve an irreducible entropy cost. (shrink)

Joseph Margolis, a relativist with respect to aesthetic qualities, has argued that nonrelativists must produce a theory of perception capable of providing a basis for the distinction between an object’s actually possessing a specified aesthetic quality and an object’s only seeming to possess it. Although I think Margolis is probably right on the point, my concern is not with the need for the non relativist to produce such a theory; rather, it is with the need for the relativist to give (...) an account of the perception of aesthetic qualities. (shrink)

I elucidate a frame of mind that David Wiggins callsrespect for nature, which he understands as a special attitude toward asui generisobject, Natureas such. A person with this frame of mind takes nature to impose defeasible limits on her action, so that there are some courses of action that she will refuse even to entertain, except in circumstances of dire exigency. I defend the reasonableness of respect for nature, drawing upon considerations in Wiggins's work. But I argue that the natural (...) systems that comprise the proper object of respect for nature are notsui generis; they are kindred, for practical reason, to complex social, political, and economic systems that we inhabit. I argue that it is reasonable to treat all such valuable systems with a similar respect, and that this respect is continuous with the respect we owe to persons and to valuable objects more generally. In all of these cases, respect consists, in part, in a disposition to defeasible constraints on practical deliberation. (shrink)

Contributors consider the limits of our knowledge of a world of unlimited knowability by examining philosophical thought from the Classical Greeks to the present.

Many mental health clinicians participate in the use of social media in their professional and personal lives. There are a number of ethics issues and challenges associated with this social media use, particularly with regard to self-disclosure. In this comment, key issues relevant to social media use and self-disclosure are addressed including relevant ethics guidance for participating in social media; social media use, boundaries, and multiple relationships; informed consent and the social media policy; and preparation of our next generation for (...) working ethically and effectively in the digital world. These challenges are examined and recommendations for addressing each of them in a thoughtful and proactive manner are made with a focus on each mental health professional’s overarching ethics obligations to those we serve. (shrink)

A question dating to Mardešić and Prasolov’s 1988 work [S. Mardešić and A. V. Prasolov, Strong homology is not additive, Trans. Amer. Math. Soc. 307(2) (1988) 725–744], and motivating a considerable amount of set theoretic work in the years since, is that of whether it is consistent with the ZFC axioms for the higher derived limits [Formula: see text] [Formula: see text] of a certain inverse system [Formula: see text] indexed by [Formula: see text] to simultaneously vanish. An equivalent formulation (...) of this question is that of whether it is consistent for all [Formula: see text]-coherent families of functions indexed by [Formula: see text] to be trivial. In this paper, we prove that, in any forcing extension given by adjoining [Formula: see text]-many Cohen reals, [Formula: see text] vanishes for all [Formula: see text]. Our proof involves a detailed combinatorial analysis of the forcing extension and repeated applications of higher-dimensional [Formula: see text]-system lemmas. This work removes all large cardinal hypotheses from the main result of [J. Bergfalk and C. Lambie-Hanson, Simultaneously vanishing higher derived limits, Forum Math. Pi 9 (2021) e4] and substantially reduces the least value of the continuum known to be compatible with the simultaneous vanishing of [Formula: see text] for all [Formula: see text]. (shrink)

This article explores the influence of Winnicott’s conceptual constellation of early childhood, play, use, transitional phenomena, and transitional object upon Agamben’s thinking of contemporary historical exigency.

Schelling’s System of Transcendental Idealism is usually considered to be either (1) an early Fichtean-influenced work that gives little insight into Schelling’s philosophy or (2) a text focusing on self-consciousness and aesthetics. I argue that Schelling’s System develops a subtle conception of history which originates in a dialogue with Kant and Hegel (concerning the question of teleology) and concludes in proximity to an Idealist version of Spinoza. In this way, Schelling develops a philosophy of history which is, simultaneously, a dialectical (...) engagement with the history of philosophy. (shrink)

My analysis in the following paper will focus on a subtle develop­ment in Heidegger’s interpretation of the theme of memory, from the period of his early Freiburg lectures to Being and Time and then in the works of the late 1920s. There is in this period an apparent shift in Heidegger’s understanding of this theme, which comes to light above all in his way of examining memory in the 1921 Freiburg course lectures Augustine and Neo-Platonism, then in Being and Time (...) (1927) and finally in the 1928 lectures on the metaphysical foundations of logic (Metaphysische Anfangsgründe der Logik im Ausgang von Leibniz) and Kant and the Problem of Metaphysics (1929). This shift is of interest, as I will argue, not only in indicating an internal development of Heidegger’s thinking, but above all in regard to the problem of the finitude of memory which Heidegger brings into focus and which I will interpret in my concluding remarks. (shrink)

Despite anxieties about the growing power of neo-liberalism, the crisis of the EU and the upsurge of right-wing political movements, it is important to recognize that utopian movements on the left have also in recent years been symbolically revitalized and organizationally sustained. This article analyses three recent social upheavals as utopian civil society movements, placing the 2008 US presidential campaign of Barack Obama, the Egyptian uprising in Tahrir Square and the Occupy Movement in the USA inside the narrative arc that (...) began with the non-violent democratic uprisings against authoritarian governments four decades earlier. In this new utopian surge, however, there is an unprecedented connection of eastern and western impulses, demonstrating that the tide of democratic thought and action is hardly confined to Judeo-Christian civilizations. (shrink)

How shall we expand our appreciation of the beauties of nature? One set of resources for this project is the writings of John Muir (1838–1914). At the age of eleven, Muir came with family from Scotland to the United States, where, after working on family farms and taking a few science courses at the University of Wisconsin, he set forth on wide-ranging travels that led him to Yosemite in eastern California. My First Summer in the Sierra records his life-changing discovery. (...) He had long sought a soul-satisfying realization of divine beauty in nature, and his quest finally found fulfillment. Eventually, he was led into action to share and protect what had nourished him so deeply. He would crystallize his.. (shrink)