The assessment of nanotechnology applications such as nanocarrier-based targeted drug delivery has historically been based mostly on toxicological and safety aspects. The use of nanocarriers for TDD, a leading-edge nanomedical application, has received little study from the angle of experts’ perceptions and acceptability, which may be reflected in how TDD applications are developed. In recent years, numerous authors have maintained that TDD assessment should also take into account impacts on ethical, environmental, economic, legal, and social issues in order to lead (...) to socially responsible innovation. Semi-structured interviews were conducted with French and Canadian researchers and research trainees with diverse disciplinary backgrounds and involved in research related to emerging technologies. The interviews focussed on scenarios presenting two types of TDD nanocarriers in two contexts of use. Content and inductive analyses of interviews showed how facets of perceived impacts such as health, environment, social cohabitation, economy, life and death, representations of the human being and nature, and technoscience were weighed in acceptability judgments. The analyses also revealed that contextual factors related to device, to use, and to user influenced the weighting assigned to perceived impacts and thus contributed to variability in interviewees’ judgments of acceptability. Giving consideration to researchers’ perspective could accompany first steps of implementation and development of nanomedicine by producing a first, but wide, picture of the acceptability of nanocarrier-based TDD. (shrink)

A Study of the History and Philosophy of Category Theory Jean-Pierre Marquis. to say that objects are dispensable in geometry. What is claimed is that the specific nature of the objects used is irrelevant. To use the terminology already ...

Jean-Pierre Vernant delineates a compelling new vision of ancient Greece that takesus far from the calm and familiar images of Polykleitos and the Parthenon, and reveals a culture ofslavery, of blood sacrifice, of perpetual and ritualized warfare, of ceremonial hunting andecstasies.In his provocative discussions of various institutions and practices including war,marriage, and the city state, Vernant unveils a complex and previously unexplored intersection ofthe religious, social, and political structures of ancient Greece. He concludes with a genealogy ofthe study (...) of myth from antiquity to the present, and offers a critique of structuralism.Jean-PierreVernant is Professor Emeritus of Comparative Study of Ancient Religions at the College de France inParis. (shrink)

Here Jean-Pierre Changeux elucidates our current knowledge of the human brain, taking an interdisciplinary approach and explaining in layman's terms the complex theories and scientific breakthroughs that have significantly improved our ...

Jean Pierre-Vernant and Pierre Vidal-Naquet are leaders in a contemporary French classical scholarship that has produced a a stunning reconfiguration of Greek thought and literature. In this work, published here as a single volume, the authors present a disturbing and decidedly non-classical reading of Greek tragedy that insists on its radical discontinuity with our own outlook and with our social, aesthetic, and psychological categories. Originally published in French in two volumes, this new single-volume edition includes revised essays (...) from volume one and is the first English translation of both volumes.Pierre Vidal-Naquet is Director of Studies and Professor of Sociology at the Ecole Pratique des Hautes Etudes in Paris. Jean Pierre-Vernant is Professor Emeritus of Comparative Study of Ancient Religions at the Coll?ge de France. Janet Lloyd is a translator and writer living in England. Distributed for Zone Books. (shrink)

Jean-Paul Sartre: Mind and Body, Word and Deed celebrates Sartre's polyvalence with an examination of Sartrean philosophy, literature, and politics. In four distinct yet related sections, twelve scholars from three continents examine Sartre's thought, writing and action over his long career. "Sartre and the Body" reappraises Sartre's work in dialogue with other philosophers past and present, including Maine de Biran, Maurice Merleau-Ponty and Didier Anzieu. "Sartre and Time" offers a first-hand account by Michel Contat of Sartre and Beauvoir working (...) together, and a "philosophy in practice" analysis by François Noudelmann. "Ideology and Politics" uses Sartrean notions of commitment and engagement to address modern and contemporary politics, including insights into Castro, De Gaulle, Sarkozy and Obama. Finally, an important but neglected episode of Sartre's life the visit that he and Beauvoir made to Japan in 1966 is narrated with verve and humour by Professor Suzuki Michihiko, who first met Sartre during that visit and remained in touch subsequently. Taken together, these twelve chapters make a strong case for the continued relevance of Sartre today. (shrink)

Jean-Pierre Dupuy, prophet of what he calls "enlightened doomsaying," has long warned that modern society is on a path to self-destruction. In this book, he pleads for a subversion of this crisis from within, arguing that it is our lopsided view of religion and reason that has set us on this course. In denial of our sacred origins and hubristically convinced of the powers of human reason, we cease to know our own limits: our disenchanted world leaves us (...) defenseless against a headlong rush into the abyss of global warming, nuclear holocaust, and the other catastrophes that loom on our horizon. Reviving the religious anthropology of Max Weber, Emile Durkheim, and Marcel Mauss and in dialogue with the work of René Girard, Dupuy shows that we must remember the world's sacredness in order to keep human violence in check. A metaphysical and theological detective, he tracks the sacred in the very fields where human reason considers itself most free from everything it judges irrational: science, technology, economics, political and strategic thought. In making such claims, The Mark of the Sacred takes on religion bashers, secularists, and fundamentalists at once. Written by one of the deepest and most versatile thinkers of our time, it militates for a world where reason is no longer an enemy of faith. (shrink)

An examination of the fundamental role cybernetics played in the birth of cognitive science and the light this sheds on current controversies. The conceptual history of cognitive science remains for the most part unwritten. In this groundbreaking book, Jean-Pierre Dupuy—one of the principal architects of cognitive science in France—provides an important chapter: the legacy of cybernetics. Contrary to popular belief, Dupuy argues, cybernetics represented not the anthropomorphization of the machine but the mechanization of the human. The founding fathers (...) of cybernetics—some of the greatest minds of the twentieth century, including John von Neumann, Norbert Wiener, Warren McCulloch, and Walter Pitts—intended to construct a materialist and mechanistic science of mental behavior that would make it possible at last to resolve the ancient philosophical problem of mind and matter. The importance of cybernetics to cognitive science, Dupuy argues, lies not in its daring conception of the human mind in terms of the functioning of a machine but in the way the strengths and weaknesses of the cybernetics approach can illuminate controversies that rage today—between cognitivists and connectionists, eliminative materialists and Wittgensteinians, functionalists and anti-reductionists. Dupuy brings to life the intellectual excitement that attended the birth of cognitive science sixty years ago. He separates the promise of cybernetic ideas from the disappointment that followed as cybernetics was rejected and consigned to intellectual oblivion. The mechanization of the mind has reemerged today as an all-encompassing paradigm in the convergence of nanotechnology, biotechnology, information technology, and cognitive science. The tensions, contradictions, paradoxes, and confusions Dupuy discerns in cybernetics offer a cautionary tale for future developments in cognitive science. (shrink)

This volume is about searching for fundamental theory in physics which has become somewhat elusive in recent decades. Like a group of blind men investigating an elephant, one physicist postulates the trunk as a hose, another a leg as a tree, the body a wall or barrier, the tail a rope and the ears as a fan. The organizers of the Vigier series symposia strongly believe cross polination by exploring many avenues of seemingly disparate research is key to breakthrough discovery (...) and solicited papers on all areas of physics deemed pertinent in Astrophysics, Cosmology, nuclear physics, quantum theory, electromagnetism, thermodynamics, vacuum field theory and topology. (shrink)

There were three such assumptions required, one explicitly stated, and two not made explicit until Bayle. The explicit one was a certain commonly accepted double understanding of ‘destruction’: a ‘natural’ version, which made it no more than a change in a particular arrangement or ‘organization’ of particles through which an aggregate was destroyed by losing its identity, and a metaphysical version, which entailed the actual annihilation of a substance. It was assumed that the latter could be accomplished only by miraculous (...) supra-natural means available only to God. Thus, if it could be shown that the soul was ‘without parts,’ it followed that the soul was ‘naturally’ indestructible and thus immortal. Bayle summarized the Cartesian argument to immortality as follows. (shrink)

An eminent neurobiologist reflects on the human brain, connecting recent scientific findings with ideas from an array of other disciplines.

Self-deception is one of the topics that lends itself best to the task of exploring the possibilities of cross-fertilization between 'continental philosophy' and 'analytic philosophy'. Fifty years ago, in Being and Nothingness, Sartre defined the core notion of 'Bad Faith' as lying to oneself. On the other side of the Atlantic, self-deception has become one of the most exciting puzzles in the philosophy of mind, and a number of paradoxes encountered by the theory of rational choice involve that very same (...) notion. One of the objectives is to show that bridges can be thrown over the gap between the two traditions, but also that both of them make self-deception too intrapsychic and suffer from a serious individualistic bias. The conference was intended to explore the intersubjective and social dimensions of self-deception. (shrink)

Appartient-il au philosophe de fixer strictement la compréhension de notre concept d'art, ou doit-il limiter sa tâche à celle d'une clarification de ses usages? À cette question, les textes de Jean-Pierre Cometti réunis dans ce volume répondent en choisissant la voie d'une esthétique « minimale », qui renonce aux vertiges de l'ontologie et aux ambitions définitionnelle de la philosophie analytique de l'art, tout en prenant acte du caractère caduc des grands récits spéculatifs hérités de l'esthétique idéaliste ou des (...) mirages de la déconstruction. (shrink)

Erasme l'avançait : «On ne naît pas humain, on le devient.» Mais comment peut-on le devenir? Quelles évolutions, quelles contraintes doit-on accepter, dès l'enfance puis tout au long de son existence, pour pouvoir vivre véritablement comme un homme? Et en quoi la société dans laquelle nous vivons favorise-t-elle ou empêche-t-elle ce parcours vers l'humanisation? Autant de questions que Jean-Pierre Lebrun travaille à clarifier depuis de très nombreuses années. Refusant à la fois la nostalgie d'un passé idéalisé et d'être (...) aveuglé par les sirènes du «progrès», il se demande si nous sommes encore capables, voire soucieux, de désirer. Sachant que le désir, le propre de l'homme, a affaire au langage et au manque. Et qu'il se différencie de la jouissance, comblante et par là même mortifère. Or notre société dite néolibérale, imposant la recherche éperdue de ladite jouissance, confondant égalité et égalitarisme, affaiblissant la fonction paternelle au nom du rejet, certes légitime, du patriarcat, tend à dévaloriser tout ce qu'implique la condition humaine. Ce qui a des conséquences majeures, et très concrètes, qu'explore ici Jean-Pierre Lebrun, dans tous les domaines de la vie individuelle et collective : la politique, l'éducation, la culture, le psychisme et ses pathologies, mais aussi la vie conjugale ou les modes de consommation. Une réflexion profonde mais accessible, du point de vue de la psychanalyse, sur les problèmes cruciaux que doit affronter l'homme contemporain. (shrink)

A monster stalks the earth—a sluggish, craven, dumb beast that takes fright at the slightest noise and starts at the sight of its own shadow. This monster is the market. The shadow it fears is cast by a light that comes from the future: the Keynesian crisis of expectations. It is this same light that causes the world’s leaders to tremble before the beast. They tremble, Jean-Pierre Dupuy says, because they have lost faith in the future. What Dupuy (...) calls Economy has degenerated today into a mad spectacle of unrestrained consumption and speculation. But in its positive form—a truly political economy in which politics, not economics, is predominant—Economy creates not only a sense of trust and confidence but also a belief in the open-endedness of the future without which capitalism cannot function. In this devastating and counterintuitive indictment of the hegemonic pretensions of neoclassical economic theory, Dupuy argues that the immutable and eternal decision of God has been replaced with the unpredictable and capricious judgment of the crowd. The future of mankind will therefore depend on whether it can see through the blindness of orthodox economic thinking. (shrink)

"This wonderfully eloquent and playful colloquy of two brilliant minds gives new life to the old notion of Dialogue, a sadly forgotten form now.... I "love" this book!

This book is an attempt to redress this balance and reopen the dialogue between Beauvoir's writings and film studies.

In a remarkable exchange between neuroscientist Jean-Pierre Changeux and philosopher Paul Ricoeur, this book explores the vexed territory between these...

The infant prodigy (1905-1917) -- Violence and counter-violence (1917-1920) -- Intellectual and emotional mastery (1920-1929) -- Melancholia: masculinity challenges (1929-1939) -- The Phoney War (September 1939-May 1940): stoicism/authenticity -- Sartre's war (June 1940-1945): the individual and the collective -- Sartre and Beauvoir -- Sartre's relationships: to be or not to be intimate.

L'intériorité et l'expression de l'intériorité occupent une place significative en philosophie. Au cours des dix dernières années de sa vie, Wittgenstein leur a consacré une large part de ses réflexions en s'engageant dans des voies inattendues qui rompent avec les présupposés ordinaires et s'ouvrent sur des perspectives inédites dont ses remarques sur la " philosophie de la psychologie " constituent le centre. Mais l'intérêt de Wittgenstein pour l'intériorité vise moins à en prononcer la liquidation qu'à la débarrasser des confusions qui (...) en obscurcissent le sens et à mieux en dessiner le visage. L intériorité, qui peut être une sorte de maladie, douce ou terrible, insidieuse, attrayante ou repoussante, est comme la face visible de notre langage et de notre vie dans ce qui les fait nôtres, les soustrayant ainsi à l'indifférence, à la monotonie et par conséquent à la mort. Cet essai sur Wittgenstein et la philosophie de la psychologie explore cette partie de son œuvre en s'efforçant d'en saisir la portée pour une partie des questions qui se posent aujourd'hui en esthétique, voire en éthique, ainsi qu'en philosophie du langage et de l'esprit. (shrink)

La référence à la norme spontanément admise et reconnue par tous, à l'idéal implicitement partagé, à la hiérarchie véhiculée par la tradition que les générations se donnent la charge de transmettre, autrement dit au Tiers, est aujourd'hui remise en cause. Nous voulons être une société pluraliste, évoquant des références diverses, prenant en compte différents modèles culturels et donnant place aux singularités. La coordination de l'action collective en est rendue d'autant plus complexe. Il faut désormais arriver à construire des normes à (...) plusieurs, en fonction des situations, avec les protagonistes eux-mêmes, au cas par cas. Dans le même mouvement, nous entendons de plus en plus qu'" il manque du tiers ", qu'" il faudrait davantage faire tiers ", qu'" il y a moyen de faire tiers autrement qu'en se référant au grand Tiers d'hier "! Mais en un mot comme en cent, la question se pose avec acuité : qu'est-ce encore que le Tiers, qu'un tiers? C'est cette interrogation qu'ont soutenue, pendant cinq ans, des psychanalystes, philosophes, sociologues..., au sein d'un groupe de travail dans le cadre du Département de communication de l'Université de Louvain. Ils font ici le point sur leurs débats. (shrink)

Il n'y a pas de " théorie leibnizienne du vivant " mais on peut, à l'aide de certains outils conceptuels et sur la base de certaines orientations du discours leibnizien, porter un regard sur le vivant qui le saisisse comme la continuité ...

t. 1. Le phénomène humain : contraction de texte et commentaires.

The development of a scientific theory of mind was thus significantly delayed."--BOOK JACKET.

It is commonly assumed across the language sciences that some semantic participant information is lexically encoded in the representation of verbs and some is not. In this paper, we propose that semantic obligatoriness and verb class specificity are criteria which influence whether semantic information is lexically encoded. We present a comprehensive survey of the English verbal lexicon, a sentence continuation study, and an on-line sentence processing study which confirm that both factors play a role in the lexical encoding of participant (...) information. (shrink)

This paper describes a comprehensive survey of English verbs that semantically allow or require an Instrument role. It sheds light on the nature of Instrument roles and instrumentality by examining the distribution in semantic space of those verbs. We show first that verbs that semantically require instruments are typically semantically more complex than predicted by current theories of the structural complexity of verb meanings. We also show that verbs that require or allow instruments constrain the end states of situations they (...) describe more than they constrain the agent's initial activity. Our survey further suggests that the causal role played by the instrument is more varied than suggested by previous studies and requires the introduction of a new subtype of causal relation, which we dub helping. Finally, our survey demonstrates that verbs that semantically require an instrument cluster together more closely in semantic space and constrain the instrument's role and properties more than verbs that merely allow the presence of an instrument. (shrink)

L'État actionnaire de la télévision publique est soucieux du rendement social de son investissement. Les programmes des chaînes publiques doivent être globalement vus par le plus grand nombre. Mais en même temps, chaque entité du service public doit respecter un cahier des charges et ne peut être une simple addition de «pièges à audience». Au programmateur de gérer ces paradoxes en forgeant une grille qui s'appuie sur ces contraintes et affirme la relation particulière de chaque chaîne avec le public. L'audience (...) est la récompense d'une programmation généreuse, qui prend des risques et produit du sens. La grille de France 3 s'est construite autour des concepts de proximité et de curiosité; France 2 doit être une grande chaîne de divertissement, d'information et de création; France 5 est une chaîne pédagogique qui tente d'apporter à certains publics qui en ont besoin , des clés pour mieux comprendre la réalité de tous les jours.As the main shareholder in public television, the State is of course concerned by the level of social profit in return for its investment. Overall, public channels' programme schedules should be seen by the largest audience possible. But at the same time, each public channel has to respect certain obligations and cannot be a simple accumulation of "audience traps". It is the programmer’s responsibility to manage these paradoxes when constructing a schedule which should be based on these very constraints while affirming each channel's particular relationship with its audience. High audience ratings are the reward for generous scheduling in which risks are taken and a certain meaning is produced. France 3's programming was built around the concepts of proximity and curiosity; France 2 is intended to be a major entertainment, information and creation channel; France 5 is an educational channel aiming to bring keys to better understand everyday reality to certain audiences who need it, particularly young people. (shrink)

This paper first queries what type of concept of emergence, if any, could be connected with the different chemical activities subsumed under the label ‘quantum chemistry’. In line with Roald Hoffmann, we propose a ‘rotation to research laboratory’ in order to point out how practitioners hold a molecular whole, its parts, and the surroundings together within their various methods when exploring chemical transformation. We then identify some requisite contents that a concept of emergence must incorporate in order to be coherent (...) from the standpoint of the scientific practices involved. In this respect, we finally propose a relational form of emergence which pays attention to the constitutive role of the modes of intervention and to the co-definition of the levels of organization. No metaphysical distinction between the higher and basic levels of organization is supposed, but only a plurality of modes of access. Moreover, these modes of access are not construed as mere ways of revealing intrinsic patterns of organization but, on the contrary, are considered to be active elements on which the constitution of those patterns depends. What is at stake in this paper is therefore not an ontological form of emergence but an agnostic one which fits what chemists do in their daily work. (shrink)

1 INSERM-CEA Unit 562, Cognitive Neuroimaging, Service Hospitalier Fre´de´ric Joliot, Orsay, France, 2 CNRS URA2182 Re´cepteurs and Cognition, Institut Pasteur, Paris, France.

Le réalisme scientifique occupe une place centrale dans le système philosophique de Mario Bunge. Au cœur de cette thèse, on trouve l’affirmation selon laquelle nous pouvons connaître le monde partiellement. Il s’ensuit que les théories scientifiques ne sont pas totalement vraies ou totalement fausses, mais plutôt partiellement vraies et partiellement fausses. Ces énoncés sur la connaissance scientifique, à première vue plausible pour quiconque est familier avec la pratique scientifique, demandent néanmoins à être clarifiés, précisés et, ultimement, à être inclus dans (...) un cadre théorique plus large et rigoureux. Depuis ses toutes premières publications sur ces questions et jusqu’à récemment, Mario Bunge n’a cessé d’interpeller les philosophes afin qu’ils développent une théorie, au sens propre du terme, de la vérité partielle afin de clarifier les enjeux épistémologiques liés au réalisme scientifique. Bunge a lui-même proposé plusieurs parties de cette théorie au fil des années, mais aucune de ces propositions ne l’a satisfait pleinement et la construction de cette théorie demeure un problème entier. Dans ce texte, nous passerons rapidement en revue certaines des approches proposées par Bunge dans ses publications et nous esquisserons certaines pistes qui devraient servir à tout le moins de desiderata pour la construction d’une théorie de la vérité partielle. (shrink)

Fefermans argument is indeed convincing in a certain context, it can be dissolved entirely by modifying the context appropriately.

In this paper, we look at Bourbaki’s work as a case study for the notion of mathematical style. We argue that indeed Bourbaki exemplifies a mathematical style, namely the structuralist style.

If such a thing as nanoethics is possible, it can only develop by confronting the great questions of moral philosophy, thus avoiding the pitfalls so common to regional ethics. We identify and analyze some of these pitfalls: the restriction of ethics to prudence understood as rational risk management; the reduction of ethics to cost/benefit analysis; the confusion of technique with technology and of human nature with the human condition. Once these points have been clarified, it is possible to take up (...) some weighty philosophical and metaphysical questions which are not new, but which need to be raised anew with respect to nanotechnologies: the artificialization of nature; the question of limits; the role of religion; the finiteness of the human condition as something with a beginning and an end; the relationship between knowledge and know-how; the foundations of ethics. (shrink)

Mulliken proposed an Aufbauprinzip for the molecules on the basis of molecular spectroscopy while establishing, point by point, his concept of molecular orbit. It is the concept of electronic state which becomes the lever for his attribution of electronic configurations to a molecule. In 1932, the concept of orbit was transmuted into that of the molecular orbital to integrate the probabilistic approach of Born and to achieve quantitative accuracy. On the basis of the quantum works of Hund, Wigner, Lennard-Jones and (...) group theory, he suggested the fragment method to establish the characteristics of molecular orbital for polyatomic molecules. These developments make it possible to bring elements of thought on the relation between a molecular whole and its parts . An operational realism combined with the second law of thermodynamics can pave the way for interesting tracks in the mereological study of chemical systems. (shrink)