Our understanding of neuronal migration has been advanced by multidisciplinary approaches. At the cellular level, tangential and radial modes of neuronal migration contribute to different populations of neurons and have differential dependence on glial cells. At the molecular level, extracellular guidance cues have been identified and intracellular signal transduction pathways are beginning to be revealed. Interestingly, mechanisms guiding axon projection and neuronal migration appear to be conserved with those for chemotactic leukocytes. BioEssays 24:821–827, 2002. © 2002 Wiley Periodicals, Inc.

‘Representing Race and Gender’ was the first course in the undergraduate curriculum of the Department of Gender and Cultural Studies at the University of Sydney to foreground race. This paper provi...

The COVID-19 pandemic has witnessed an increase and amplification of anti-Asian racism and violence across the globe. Stop AAPI Hate1 in the United States and the COVID-19 Racism Incident Report2 i...

In recent decades conservation biology has achieved a high position among the sciences. This is certainly true of South Africa, a small country, but the third most biodiverse in the world. This article traces some aspects of the transformation of South African wildlife management during the 1930s to the 1960s from game reserves based on custodianship and the "balance of nature" into scientifically managed national parks with a philosophy of "command and control" or "management by intervention." In 1910 the four (...) British colonies had formed the Union of South Africa, and by the 1920s there was wide acceptance of national parks, a development influenced by their success in the United States. It was not, however, until after the Second World War, that management of the expanding conservation estate altered from a rather unsystematic laissez faire variety, into more scientifically informed management practices with an efficient bureaucracy in charge. This was achieved by modifications in organizational structures and institutional cultures initiated by a change of government in 1948 which, this article argues, impacted in turn on wildlife management and shaped and professionalized many aspects of that field science. "Management by intervention" was the hallmark of South African wildlife and conservation biology from the 1960s until recently, when there have been shifts towards "adaptive resource management" in a period of further change in the country's politics. (shrink)

In recent decades conservation biology has achieved a high position among the sciences. This is certainly true of South Africa, a small country, but the third most biodiverse in the world. This article traces some aspects of the transformation of South African wildlife management during the 1930s to the 1960s from game reserves based on custodianship and the "balance of nature" into scientifically managed national parks with a philosophy of "command and control" or "management by intervention." In 1910 the four (...) British colonies had formed the Union of South Africa, and by the 1920s there was wide acceptance of national parks, a development influenced by their success in the United States. It was not, however, until after the Second World War, that management of the expanding conservation estate altered from a rather unsystematic laissez faire variety, into more scientifically informed management practices with an efficient bureaucracy in charge. This was achieved by modifications in organizational structures and institutional cultures initiated by a change of government in 1948 which, this article argues, impacted in turn on wildlife management and shaped and professionalized many aspects of that field science. "Management by intervention" was the hallmark of South African wildlife and conservation biology from the 1960s until recently, when there have been shifts towards "adaptive resource management" in a period of further change in the country's politics. (shrink)

This article uses a core group of three arguments to support the contention that Yellowstone National Park's thermal sites deserve special efforts to preserve them, and that this goes above and beyond the general spirit motivating the national parks. It considers arguments having to do with educational value and rarity, and an argument that relies on aesthetic constructs. For purposes of evaluating the notion of rarity, comparison is made to work on the rare saline water preserve of Mono Lake. (...) Part and parcel of this line of debate has to do with the notion that there has been a general lack of commentary on the value of geothermal areas. The work of William J. Fritz and Robert C. Thomas, Marc Hendrix, and others is cited. (shrink)

Eliminating pain is problematic when it comes to caring for people with disabilities or chronic pain. This paper locates the drive to completely eliminate pain as a project of the Enlightenment and contrasts it with the tradition of interpreting suffering throughout the Christian tradition. I introduce Jane Austen’s novel Mansfield Park as a way to continue the tradition of interpretative suffering after the Enlightenment. Using textual analysis of Jane Austen’s Mansfield Park, I demonstrate how the novel’s (...) heroine, Fanny Price, is able to resist the drive to eliminate pain through her contemplative reflection on suffering which allows her to participate in right relationships with others and God. Finally, I offer twenty-first century applications of Mansfield Park by addressing changes we can make in the church and the clinic to understand better the role pain plays in Christian life and community. (shrink)

Call the norms of inquiry zetetic norms. How are zetetic norms related to epistemic norms? At first glance, they seem quite closely connected. Aren't epistemic norms norms that bind inquirers qua inquirers? And isn't epistemology the place to look for a normative theory of inquiry? While much of this thought seems right, this paper argues that the relationship between the epistemic and the zetetic is not as harmonious as one might have thought and liked. In particular, this paper argues that (...) some familiar contemporary epistemic norms are in tension with, and even in conflict with, central zetetic norms. (shrink)

In contemporary philosophy of science, the no-miracles argument and the pessimistic induction are regarded as the strongest arguments for and against scientific realism, respectively. In this paper, I construct a new argument for scientific realism which I call the anti-induction for scientific realism. It holds that, since past theories were false, present theories are true. I provide an example from the history of science to show that anti-inductions sometimes work in science. The anti-induction for scientific realism has several advantages over (...) the no-miracles argument as a positive argument for scientific realism. (shrink)

The Aesthetics of Design offers the first full treatment of design in the field of philosophical aesthetics, challenging the discipline to broaden its scope to include the quotidian objects and experiences of our everyday lives and concerns ...

Localism is the view that the unit of evaluation in the scientific realism debate is a single scientific discipline, sub-discipline, or claim, whereas individualism is the view that the unit of evaluation is a single scientific theory. Localism is compatible, while individualism is not, with a local pessimistic induction and a local selective induction. Asay (2016) presents several arguments to support localism and undercut globalism, according to which the unit of evaluation is the set of all scientific disciplines. I argue (...) that some of his arguments clash with localism as well as with globalism and support individualism, and that individualism goes hand in hand, while localism does not, with the basic rule of how to evaluate an argument. (shrink)

In this paper I look at belief and degrees of belief through the lens of inquiry. I argue that belief and degrees of belief play different roles in inquiry. In particular I argue that belief is a “settling” attitude in a way that degrees of belief are not. Along the way I say more about what inquiring amounts to, argue for a central norm of inquiry connecting inquiry and belief and say more about just what it means to have an (...) inquiry or question settled. (shrink)

Localism is the view that the unit of evaluation in the scientific realism debate is a single scientific discipline, sub-discipline, or claim, whereas individualism is the view that the unit of evaluation is a single scientific theory. Localism is compatible, while individualism is not, with a local pessimistic induction and a local selective induction. Asay presents several arguments to support localism and undercut globalism, according to which the unit of evaluation is the set of all scientific disciplines. I argue that (...) some of his arguments clash with localism as well as with globalism and support individualism, and that individualism goes hand in hand, while localism does not, with the basic rule of how to evaluate an argument. (shrink)

In this paper I argue that there is a class of attitudes that have questions (rather than propositions or something else) as contents.

This book provides philosophers of science with new theoretical resources for making their own contributions to the scientific realism debate. Readers will encounter old and new arguments for and against scientific realism. They will also be given useful tips for how to provide influential formulations of scientific realism and antirealism. Finally, they will see how scientific realism relates to scientific progress, scientific understanding, mathematical realism, and scientific practice.

Philosophy and Phenomenological Research, EarlyView.

Postcolonialism offers challenging and provocative ways of thinking about colonial and neocolonial power, about self and other, and about the discourses that perpetuate postcolonial inequality and violence. Much of the seminal work in postcolonialism has been shaped by currents in philosophy, notably Marxism and ethics. "Understanding Postcolonialism" examines the philosophy of postcolonialism in order to reveal the often conflicting systems of thought which underpin it. In so doing, the book presents a reappraisal of the major postcolonial thinkers of the twentieth (...) century.Ranging beyond the narrow selection of theorists to which the field is often restricted, the book explores the work of Fanon and Sartre, Gandhi, Nandy, and the Subaltern Studies Group, Foucault and Said, Derrida and Bhabha, Khatibi and Glissant, and Spivak, Mbembe and Mudimbe. A clear and accessible introduction to the subject, "Understanding Postcolonialism" reveals how, almost half a century after decolonisation, the complex relation between politics and ethics continues to shape postcolonial thought. (shrink)

In 1814, Jane Austen published Mansfield Park, which, despite being one of her lesser-known works raised important discussions about the depiction of its historical context. Having one of the characters as a landowner in Antigua, the novel prompted readings from post-colonialist perspectives, such as Edward Said’s interpretation of the “dead silence” scene, and George Boulukos’ discussion about amelioration. These approaches to the text have probably led Patricia Rozema into using the slave-dependency as central to the Bertrams’ lives in (...) her 1999 adaptation of the book. From this point of view, this article intends to compare Jane Austen’s Mansfield Park and Patricia Rozema’s film taking into account their different approaches to slavery.Keywords: Slavery. Adaptation. Jane Austen. Patricia Rozema. Mansfield Park. ResumoEm 1814, Jane Austen publicou Mansfield Park que, apesar de ser uma de suas obras menos conhecidas, gerou importantes discussões acerca da representação de seu contexto histórico. O fato de uma das personagens ser um proprietário de terras na colônia britânica de Antigua levou a uma série de interpretações a partir de estudos pós-colonialistas, como Edward Said, em sua análise da cena do silêncio profundo, e George Boulukos, em sua discussão sobre amelioration. Essas leituras podem ter influenciado Patricia Rozema a fazer da dependência da escravidão uma marca da vida moral dos Bertram em sua adaptação do livro para o cinema. Nesse sentido, este artigo busca analisar as diferentes interpretações da escravidão no romance e no filme.Palavras-chave: Escravidão. Adaptação. Jane Austen. Patricia Rozema. Mansfield Park. (shrink)

This chapter contains sections titled: Introduction Philosophy Pitfalls, and What Is Needed to Avoid Them Institutional History at Cambridge Cambridge Philosophy Reference.

Neuroeconomics has the potential to fundamentally change the way economics is done. This article identifies the ways in which this will occur, pitfalls of this approach, and areas where progress has already been made. The value of neuroeconomics studies for social policy lies in the quality, replicability, and relevance of the research produced. While most economists will not contribute to the neuroeconomics literature, we contend that most economists should be reading these studies.

This volume tracks the evolution of Mansbridge's key contributions to democratic theory in participatory, institutional and feminist contexts through articles that span her entire career to date.

Adventures in cutting-edge ideas about consciousness, from bestselling non-fiction writer Tim Parks. Hardly a day goes by without some discussion about whether computers can be conscious, whether our universe is some kind of simulation, whether mind is a unique quality of human beings or spread out across the universe like butter on bread. Most philosophers believe that our experience is locked inside our skulls, an unreliable representation of a quite different reality outside. Colour, smell and sound, they tell us, occur (...) only in our heads. Yet when neuroscientists look inside our brains to see what's going on, they find only billions of neurons exchanging electrical impulses and releasing chemical substances. Five years ago, in a chance conversation, Tim Parks came across a radical new theory of consciousness that undercut this interpretation. This set him off on a quest to discover more about this fascinating topic and also led him to observe his own experience with immense attention. Out of My Head tells the gripping, highly personal, often surprisingly funny, story of Tim Parks' quest to discover more about this fascinating topic. It frames complex metaphysical considerations and technical laboratory experiments in terms we can all understand. Above all, it invites us to see space, time, colour and smell, sounds and sensations in an entirely new way. The world will feel more real after reading it. (shrink)

In Western political philosophy, democracy is generally the dominant view regarding what the best form of government is, and this holds even in respect to promoting minority rights. However, I argue that there is a better theory for satisfying minority interests and rights. I amass numerous studies from the social sciences demonstrating how democracy does poorly in accounting for minority interests. I then contend that a particular hybrid view that fuses a meritocracy with democracy can do a better job than (...) democracy in accounting for minority interests and in having more equal rights and fair policies coming from the legislative and executive branches. Finally, I defend this thesis from numerous counters. (shrink)

Biobanks are proliferating rapidly worldwide because they are powerful tools and organisational structures for undertaking medical research. By linking samples to data on the health of individuals, it is anticipated that biobanks will be used to explore the relationship between genes, environment and lifestyle for many diseases, as well as the potential of individually-tailored drug treatments based on genetic predisposition. However, they also raise considerable challenges for existing legal frameworks and research governance structures. This book critically examines the current governance (...) structures in place for biobanks in England and Wales. It shows that the technologies, techniques and practices involved in biobanking do not always conform neatly to existing legal principles and frameworks that apply to other areas of medical research. Using a socio-legal approach, including interview data gathered from the scientific community, this book provides unique insights and makes recommendations about appropriate governance mechanisms for biobanking in the future. It also explores the issues around the secondary use of information, such as consent and how to protect privacy, when biobanks are accessed by a number of different third parties. These issues have relevance both within England and Wales and to a wide international audience, as well as for other areas where large datasets are used.--Back cover. (shrink)

Challenges the idea held by many prominent twentieth-century Sinologists that early China experienced a “language crisis.” Jane Geaney argues that early Chinese conceptions of speech and naming cannot be properly understood if viewed through the dominant Western philosophical tradition in which language is framed through dualisms that are based on hierarchies of speech and writing, such as reality/appearance and one/many. Instead, early Chinese texts repeatedly create pairings of sounds and various visible things. This aural/visual polarity suggests that texts from (...) early China treat speech as a bodily practice that is not detachable from its use in everyday experience. Firmly grounded in ideas about bodies from the early texts themselves, Geaney’s interpretation offers new insights into three key themes in these texts: the notion of speakers’ intentions (yi), the physical process of emulating exemplary people, and Confucius’s proposal to rectify names (zhengming). Jane Geaney is Professor of Religious Studies at the University of Richmond and the author of On the Epistemology of the Senses in Early Chinese Thought. (shrink)

The importance of ethical listening -- The power of difference and values that unite -- Take off your armor and bring down the walls: adopting a listening posture -- Dolls and cages: listening as investment and care -- Deep listening: remembering and responding with intentional focus -- Hyenas and chickens: listening as invitation -- Hope for sustainable hospitality -- References -- About the author.

Causal platonism asserts that mathematical objects cause neural states in human brains. I raise the following four objections to it. (i) Quantum entanglement does not show that one object can causally affect another, although one is nontemporal, nonspatial, and unchanging. (ii) Causal platonism can neither be justified a posteriori nor a priori. (iii) To postulate mathematical media to flesh out mathematical causation is to multiply mysteries beyond necessity. (iv) To say that mathematical causation is unintelligible and inexplicable is not to (...) complain about causation in general. (shrink)

PREFATORY NOTE T may be well at the outset to say clearly what is the aim of the present volume. The title is Ancient Art and Ritual, but the reader will ...

Healthism and ableism intertwine through an imperative of normalcy and the ensuing devaluing of those who fail to meet societally dominant norms and expectations around “normal” health. This paper tracks the effect of that imperative of normalcy through current research into gut microbiome therapies, using therapies targeting fatness and autism as examples. The complexity of the gut microbiome ought to encourage us to rethink our conception of ourselves and our embeddedness in the world; instead, the microbiome is transformed into one (...) more tool for controlling unruly bodies and minds. (shrink)

The proposed new geological era, The Anthropocene (aka Age of Humans, Age of Man), marking human domination of the planet long called Mother Earth, is truly The Age of the Motherfucker. The ecocide of the Anthropocene comes from Man, the Western- and masculine- identified corporate, military, intellectual, and political class that masks itself as the exemplar of the civilized and the human. The word motherfucker was invented by the enslaved children of White slavemasters to name their mothers' rapist/owners. Man's strategic (...) motherfucking, from the personal to the planetary, is invasion, exploitation, spirit-breaking, extraction and toxic wasting of individuals, communities, and lands, for reasons of pleasure, plunder, and profit. Ecocide is attempted deicide of Mother Nature-Earth, reflecting Man's goal to come the god he first made in his own image. The motivational word Motherfucker further reveals the Anthropocene with a flip side signifying an outstanding, formidable, and inexorable force. Mother Nature-Earth is that "Mutha'" -- one defying translation into heteropatriarchal classifications of gender, one capable of overwhelming Man and not the other way around. Drawing upon Indigenous and African American scholarship, ecofeminism, ecowomanism, green activism, femme, queer, and gender non-binary philosophies, literature and arts, Afrofuturism, and popular culture, Call Your "Mutha'" contends that the Anthropocene is not evidence of Man's supremacy over nature, but that Mother Nature-Earth, faced with disrespect, is going away. It is imperative now to call the "Mutha'" by decolonizing land, bodies, and minds, ending rapism, feeding the green, renewing sustaining patterns and affirming devotion to Mother Nature-Earth. (shrink)

In _Vibrant Matter_ the political theorist Jane Bennett, renowned for her work on nature, ethics, and affect, shifts her focus from the human experience of things to things themselves. Bennett argues that political theory needs to do a better job of recognizing the active participation of nonhuman forces in events. Toward that end, she theorizes a “vital materiality” that runs through and across bodies, both human and nonhuman. Bennett explores how political analyses of public events might change were we (...) to acknowledge that agency always emerges as the_ _effect of ad hoc configurations of human and nonhuman forces. She suggests that recognizing that agency is distributed this way, and is not solely the province of humans, might spur the cultivation of a more responsible, ecologically sound politics: a politics less devoted to blaming and condemning individuals than to discerning the web of forces affecting situations and events. Bennett examines the political and theoretical implications of vital materialism through extended discussions of commonplace things and physical phenomena including stem cells, fish oils, electricity, metal, and trash. She reflects on the vital power of material formations such as landfills, which generate lively streams of chemicals, and omega-3 fatty acids, which can transform brain chemistry and mood. Along the way, she engages with the concepts and claims of Spinoza, Nietzsche, Thoreau, Darwin, Adorno, and Deleuze, disclosing a long history of thinking about vibrant matter in Western philosophy, including attempts by Kant, Bergson, and the embryologist Hans Driesch to name the “vital force” inherent in material forms. Bennett concludes by sketching the contours of a “green materialist” ecophilosophy. (shrink)