OBJECTIVE: Pilot study to characterize treatment differences between patients treated in clinical trials and those treated in a clinical setting. Previous studies have shown higher survival rates for participants in trials of cancer therapy. This difference is observed even after rates are adjusted for important covariates such as age and stage of disease. DESIGN: Retrospective chart review. SETTING: Oncology outpatient department in a tertiary care hospital. PATIENTS: Ninety women 18 to 70 years of age with early-stage breast cancer who were (...) diagnosed in 1990. Fifty-one of the women were treated through clinical trials and 39 were treated outside of clinical trials. OUTCOME MEASURES: Number of blood tests, telephone calls, clinic visits and imaging procedures as well as intensity of chemotherapy and use of radiation therapy. The age of the patient and the stage of disease were important covariates. RESULTS: After the analysis was controlled for patient age and stage of disease, patients treated through a clinical trial were more likely to receive standard-dose chemotherapy (p = 0.020, 95% confidence interval 1.20 to 200.73) and more frequent blood tests (p < 0.001, 95% confidence interval 1.02 to 1.13) than other patients treated in the clinic. CONCLUSIONS: Our results provide a plausible mechanism for the observed survival advantage for participants in clinical trials in oncology. Further study is called for. If these results are confirmed, they have important implications for informed consent to participate in clinical trials and for clinical practice. (shrink)

The organizers of the 1992 Highlands Institute seminar were kind enough to invite me to comment as a neo-pragmatist on John E. Smith's keynote paper "Experience, God, and Classical American Philosophy." It is my pleasure to do so. I read portions of both GOD AND EXPERIENCE and THE ANALOGY OF EXPERIENCE when they were published. I was impressed then, and continue to be impressed, with Professor Smith's intellectually responsible and powerful defense of Christianity, carried out, as it was, in a (...) philosophical environment where that was not the most popular thing to do. More recently, in preparation for this event, I have profited from reading THE SPIRIT OF AMERICAN PHILOSOPHY, particularly the chapters on James and Dewey. And, I can only second his presidential call in "The New Need for a Recovery of Philosophy" for a live-and-let-live attitude amongst the cacophonous multitude of those of us who call ourselves "philosophers.". (shrink)

William Dean is a tireless proponent of a public role for religion in American society, most recently in his American Academy of Religion award winning book The Religious Critic in American Culture . He writes there about the importance of, and need for, both a common American spiritual culture and public intellectuals who would understand, criticize, and innovatively rework that shared American religion. Dean represents a metaphysical strand of American pragmatism. His thought is rooted in William James’s radical empiricism, (...) Bernard Meland’s and Bernard Loomer’s empirical theology, and Alfred North Whitehead’s process metaphysics. He takes seriously what I will call the problem of cosmic estrangement. The American public religion that he advocates, among other things, is supposed to resolve that problem. Its theoretical core is Dean’s version of Whiteheadian panpsychism, which he calls ontological conventionalism. (shrink)

Pragmatism is first and foremost an intellectual self-image. It is a unique way of understanding the mental abilities that distinguish we humans from other living things on earth. The pragmatist description of our mind and its relationship to the rest of the world is a relatively new one. It has its roots in the late nineteenth and early twentieth century work of Charles Sanders Peirce, William James, and John Dewey. These philosophers, influenced by Darwinian biology among other things, redefined (...) the human mind. (shrink)

We Americans put a lot of stock in ingenuity. We admire people who come up with better mousetraps or with better ways to predict economic cycles. William James, in his early essay "Great Men and Their Environment," was the first American pragmatist to suggest that there are interesting analogies between the roles that ingenious people play in social change and bearers of genetic variations play in biological evolution.(1) He proposed that the categories in terms of which we conduct various (...) cultural activities start as idiosyncratic "brainstorms" in the heads of individual human beings, much as Darwin theorized that species start as genetic variations in ancestral organisms. When these mental variations occur in a suitable environment, they may end as new forms of science, morality, art, or religion. Such new ideas enable their bearers to cope with the world differently, and perhaps more profitably, than their ancestors did before them. Social progress when it occurs is a function of the meliorative power of this fortuitous human creativity, not of anything preprogrammed with its own logic or method. (shrink)

Sheila Davaney’s Pragmatic Historicism provides yet another opportunity for us to discuss disagreements between two kinds of pragmatism. One, which I espouse, is a non-metaphysical pragmatism. It is rooted in James’s and Dewey’s appropriation of Darwinian biology for philosophical purposes and, more recently, Donald Davidson’s philosophy of language. Richard Rorty is its most influential contemporary spokesman. The other is a metaphysical pragmatism. It is rooted in James’s radical empiricism and Whitehead’s process philosophy. In the Highlands Institute, William Dean (...) and now Davaney, among others, advocate versions of metaphysical pragmatism. (shrink)

Richard Rorty is famous, maybe even infamous, for his philosophical nonchalance. His groundbreaking work not only rejects all theories of truth but also dismisses modern epistemology and its preoccupation with knowledge and representation. At the same time, the celebrated pragmatist believed there could be no universally valid answers to moral questions, which led him to a complex view of religion rarely expressed in his writings. In this posthumous publication, Rorty, a strict secularist, finds in the pragmatic thought of John Dewey, (...) John Stuart Mill, William James, and George Santayana, among others, a political imagination shared by religious traditions. His intent is not to promote belief over nonbelief or to blur the distinction between religious and public domains. Rorty seeks only to locate patterns of similarity and difference so an ethics of decency and a politics of solidarity can rise. He particularly responds to Pope Benedict XVI and his campaign against the relativist vision. Whether holding theologians, metaphysicians, or political ideologues to account, Rorty remains steadfast in his opposition to absolute uniformity and its exploitation of political strength. (shrink)

In a volume that traverses multiple disciplines, Michael Robbins proposes that the structures of the mind that distinguish us as uniquely human also incline us towards destructive behaviours on a personal and societal level. Psychoanalysis was created by Freud in an effort to understand neurosis and psychosis, the names he gave to individual human destructiveness. His understanding was limited and incorrect because the science of evolution and the disciplines of sociology and cultural anthropology were in their infancy when he (...) formulated his ideas. He did not comprehend that destructiveness is qualitatively different in humans than in other species and he ignored the problem of how biological instincts become mental processes. These limitations left psychoanalysis with one of its most perplexing unsolved problems, the mysterious leap from mind to body. The book explains how neoteny, the prolonged period of post-natal immaturity that distinguishes humans from other animals, requires and enables complex learning from caregivers. It is the knowledge acquired from this learning and its intergenerational transmission that links the biological theory of evolution with the psychosocial theory of psychoanalysis and explains how the human species is unique. The book will be of interest to those who want to learn about how integrating the findings of evolutionary science, primatology, sociology and cultural anthroplogy with the theory of psychoanalysis expands our understanding of what makes humans unique and its implications for the future of our species, and empowers us to influence the destiny of humankind. (shrink)

An indispensable collection that re-examines what it means to belong in the world. "Where are you from?" The word cosmopolitan was first used as a way of evading exactly this question, when Diogenes the Cynic declared himself a “kosmo-polites,” or citizen of the world. Cosmopolitanism displays two impulses—on the one hand, a detachment from one’s place of origin, while on the other, an assertion of membership in some larger, more compelling collective. Cosmopolitanisms works from the premise that there is more (...) than one kind of cosmopolitanism, a plurality that insists cosmopolitanism can no longer stand as a single ideal against which all smaller loyalties and forms of belonging are judged. Rather, cosmopolitanism can be defined as one of many possible modes of life, thought, and sensibility that are produced when commitments and loyalties are multiple and overlapping. Featuring essays by major thinkers, including Homi Bhabha, Jean Bethke Elshtain, Thomas Bender, Leela Gandhi, Ato Quayson, and David Hollinger, among others, this collection asks what these plural cosmopolitanisms have in common, and how the cosmopolitanisms of the underprivileged might serve the ethical values and political causes that matter to their members. In addition to exploring the philosophy of Kant and the space of the city, this volume focuses on global justice, which asks what cosmopolitanism is good for, and on the global south, which has often been assumed to be an object of cosmopolitan scrutiny, not itself a source or origin of cosmopolitanism. This book gives a new meaning to belonging and its ground-breaking arguments call for deep and necessary discussion and discourse. (shrink)

Structural realism is considered by many realists and antirealists alike as the most defensible form of scientific realism. There are now many forms of structural realism and an extensive literature about them. There are interesting connections with debates in metaphysics, philosophy of physics and philosophy of mathematics. This entry is intended to be a comprehensive survey of the field.

Misophonia is a condition characterized by defensive motivational system emotional responding to repetitive and personally relevant sounds. Preliminary research suggests misophonia may be associated with a range of psychiatric disorders, including personality disorders. However, very little research has used clinician-rated psychometrically validated diagnostic interviews when assessing the relationship between misophonia and psychopathology. The purpose of this study was to extend the early research in this area by examining the relationship between symptoms of misophonia and psychiatric diagnoses in a sample of (...) community adults, using semi-structured diagnostic interviews. Results indicated higher misophonia symptoms were associated with more clinician-rated symptoms of personality disorders, but not other disorders. Anxiety partially mediated the relationship between personality disorder symptoms and misophonia. These results suggest misophonia may be associated with a range of psychiatric symptoms and highlight the role of anxiety in this poorly understood condition. (shrink)

Moral philosophy is the study of what morality is and what it requires of us. As Socrates said, it's about "how we ought to live"-and why. It would be helpful if we could begin with a simple, uncontroversial definition of what morality is. Unfortunately, we cannot. There are many rival theories, each expounding a different conception of what it means to live morally, and any definition that goes beyond Socrates's simple formula-tion is bound to offend at least one of them. (...) This should make us cautious, but it need not paralyze us. In this chapter, I will describe the "minimum conception" of morality. (shrink)

French social and philosophical thought has played a very significant role in the development of European and American social theory. This detailed, timely book provides a map of the production and reception of French social thought within a global sociological context. Critically comparing the work of five key theorists Derek Robbins examines how their ideas were produced and received before persuasively setting out the key differences between their philosophical and ideological positions. The book sensitively traces the cross-currents of social (...) theory and confidently leads the reader through the complex foundations of Western social thought. Each chapter represents a textual analysis of the production of a critical intellectual and focuses upon the work of: Althusser, Foucault, Aron, Lyotard, Bourdieu. This carefully crafted volume represents a significant contribution to the globalization of theory and will be essential reading for anyone interested in Western social theory and the foundations of sociological thought."--Publisher's website. (shrink)

In this chapter I discuss the role of mind perception in the categorization of individuals as moral agents and moral patients. Moral agents are defined as individuals that can commit morally wrong actions and deserve to be held accountable for those actions; moral patients are defined as individuals that can be morally wronged and whose interests are worthy of moral consideration. It is generally agreed that the attribution of moral agency and moral patiency is linked to the attribution of mental (...) capacities and traits. The chapter surveys a variety of models of mind perception, some of which focus on the representation of mental capacities, some of which focus on the representation of mental traits. The dominant model of mind perception in moral psychology is the experience-agency model (Gray et al., 2007), which divides the space of mindedness into experiential capacities like sentience and self-awareness, and agentic capacities like deliberative reasoning and self-control. Reviewing the empirical literature on moral categorization, I argue that neither the experience-agency model nor any of the major alternatives to it (i.e., the warmth-competence model, the agency-communion model, and the human nature–human uniqueness model), captures the full panoply of mental features to which everyday attributions of moral agency and moral patiency are sensitive. (shrink)

Cosmopolitanism, new and newer : Anthony Appiah -- Noam Chomsky's golden rule -- Blaming the system : Immanuel Wallerstein -- The sweatshop sublime -- Edward Said and effort -- Intellectuals in public, or elsewhere -- War without belief : Louis Menand's The Metaphysical Club -- Comparative national blaming : W.G. Sebald and the bombing of Germany.

"The lectures that follow were delivered at the Lowell Institute in Boston in November and December, 1906, and in January, 1907, at Columbia University, in New York."-Preface, pg. 3.

Current research in moral development suggests that there are two distinct modes of moral reasoning, one based on a morality of justice, the other based on a morality of care. The research presented here examines the kinds of moral reasoning used by managers in work-related conflicts. Twenty men and twenty women were randomly selected from the population of first level managers in a Fortune 100 industrial corporation. In open-ended interviews each participant was asked to describe a situation of moral conflict (...) in her or his work life. The results indicated a clearly preferred mode of moral reasoning among the participants who described moral conflicts. Nearly all of these predominated with a justice orientation. These findings suggest that a correlation between gender and preferred mode may be context specific. (shrink)

This article builds on feminist scholarship on new biologies and the body to describe the temporal politics of epigenetic research related to the human placenta. Drawing on interviews with scientists and observations at conferences and in laboratories, we argue that epigenetic research simultaneously positions placenta tissue as a way back into maternal and fetal bodies following birth, as a lens onto children’s future well-being, and as a bankable resource for ongoing research. Our findings reflect how developmental models of health have (...) helped recast the placenta as an agential organ that is uniquely responsive to environments during pregnancy and capable of embodying biological evidence about the effects of in utero experiences after birth. We develop the concept of ‘recursive embodiment’ to describe how placenta epigenetics is reimagining relationships between bodies and environments across developmental, epigenetic, and generational time, and the impacts this has for experiences of pregnancy and responsibilities related to children’s health. (shrink)

Introductory Chapter to the _Cambridge Handbook of Situated Cognition_ (CUP, 2009).

Within stakeholder literature, much attention has been given to which stakeholders "really count." This article strives to explain why organizational theorists should abandon the pursuit of "Who and What Really Counts" to challenge the assumption of a managerial perspective that defines stakeholder legitimacy. Reflecting on the paucity of employee rights and protections in marginalized work environments, I argue that as organizational researchers, we must recognize and take responsibility for the impact of our research models and visions. By confronting and rethinking (...) the foundational assumptions of stakeholder theory, business and society scholars can identify and pursue research questions that more effectively address contemporary social challenges. (shrink)

Through an integrated multi-disciplinary theory, Michael Robbins proposes that the human mind consists of two mental structures, the one we share with other animate creatures, and a capacity for reflective representational thought which is unique. As an alternative to Freud's model of the human mind as structured by the id, ego and superego, this book contends that the prolonged period of post-natal immaturity - otherwise known as neoteny - which is specific to humans, gives rise to reflective representational thought (...) that in turn allows for the acquisition of complex knowledge. Robbins examines how Freud's conception of the human mind was limited by his ignorance of the related disciplines of sociology, primatology, cultural anthropology and most notably evolution, which were then in their infancy, to explore the implications of the non-unitary nature of the human mind for us as individuals, as a society, and for our future as a species. Drawing on a broad range of influences from psychoanalysis to anthropology, biology, psychology, sociology and politics, this book will be of interest to students and scholars of these disciplines alike. (shrink)

There is widespread agreement that there should be a principle requiring that artificial intelligence be ‘explicable’. Microsoft, Google, the World Economic Forum, the draft AI ethics guidelines for the EU commission, etc. all include a principle for AI that falls under the umbrella of ‘explicability’. Roughly, the principle states that “for AI to promote and not constrain human autonomy, our ‘decision about who should decide’ must be informed by knowledge of how AI would act instead of us” :689–707, 2018). There (...) is a strong intuition that if an algorithm decides, for example, whether to give someone a loan, then that algorithm should be explicable. I argue here, however, that such a principle is misdirected. The property of requiring explicability should attach to a particular action or decision rather than the entity making that decision. It is the context and the potential harm resulting from decisions that drive the moral need for explicability—not the process by which decisions are reached. Related to this is the fact that AI is used for many low-risk purposes for which it would be unnecessary to require that it be explicable. A principle requiring explicability would prevent us from reaping the benefits of AI used in these situations. Finally, the explanations given by explicable AI are only fruitful if we already know which considerations are acceptable for the decision at hand. If we already have these considerations, then there is no need to use contemporary AI algorithms because standard automation would be available. In other words, a principle of explicability for AI makes the use of AI redundant. (shrink)

This response to Dobson and White’s call for a feminine firm argues that such a concept is based on amisinterpretation of Gilligan’s research. Moreover, virtue ethics and feminine ethics do not share a common approach to nurturing relationships or the moral orientation of care. Acknowledging the worthwhile goals of Dobson and White’s endeavor, the feminist firm is presented as offering greater potential to achieve these goals.

This paper reviews the paper by Kuzma, Najmaie, and Larson that looks at what can be learned from the experience with genetically engineered organisms for oversight of emerging technologies more generally. That paper identifies key attributes of a good oversight system: promoting innovation, ensuring safety, identifying benefits, assessing costs, and doing so all while building public confidence. In commenting on that analysis, this paper suggests that looking at “oversight” in three phases — research and development, regulatory review, and market acceptance (...) — can help to determine when certain of these attributes should take precedence over others and how to structure remedies when an error occurs. The result is an approach that is precautionary with respect to research and development, prudent and open to public input in the regulatory review stage, and purposefully persuasive once market acceptability is at stake, with remedies that are risk-containing in the first phase, risk-managing in the second, and risk-assuaging in the third. Combining the key attributes with the idea of three phases can help attune oversight to society's needs. (shrink)

An accessible introduction to cultural theory and an original polemic about the purpose of criticism. What is criticism for? Over the past few decades, violent disagreements over that question in the academy have burst into the news media. These conflicts have renewed the Culture Wars over the legacy of the 1960s, becoming entangled in national politics and leading to a new set of questions. Does a concern with race, gender, and sexuality, with unacknowledged power and privilege, with identity, give present (...) critics the right to criticize the great works of the past? If we have learned to see those works in terms of historical differences rather than universal truths, how is it that they speak to us at all? In the study of the world's cultures, there is more than one way to avoid being Eurocentric; which way should we choose? Re-examining key thinkers since 1970, including Walter Benjamin, Michel Foucault, Judith Butler, Edward Said, Hortense Spillers, Fredric Jameson, and Stuart Hall, Criticism and Politics offers both a non-specialist introduction to recent cultural theory and a strong new interpretation of how this theory applies to the everyday issue of what cultural critics do and how they should feel about what they do. (shrink)

Many industry leaders and academics from the field of machine ethics would have us believe that the inevitability of robots coming to have a larger role in our lives demands that robots be endowed with moral reasoning capabilities. Robots endowed in this way may be referred to as artificial moral agents. Reasons often given for developing AMAs are: the prevention of harm, the necessity for public trust, the prevention of immoral use, such machines are better moral reasoners than humans, and (...) building these machines would lead to a better understanding of human morality. Although some scholars have challenged the very initiative to develop AMAs, what is currently missing from the debate is a closer examination of the reasons offered by machine ethicists to justify the development of AMAs. This closer examination is especially needed because of the amount of funding currently being allocated to the development of AMAs coupled with the amount of attention researchers and industry leaders receive in the media for their efforts in this direction. The stakes in this debate are high because moral robots would make demands on society; answers to a host of pending questions about what counts as an AMA and whether they are morally responsible for their behavior or not. This paper shifts the burden of proof back to the machine ethicists demanding that they give good reasons to build AMAs. The paper argues that until this is done, the development of commercially available AMAs should not proceed further. (shrink)

In discussion on consciousness and the hard problem, there is an unquestioned background assumption, namely, our experience is stored in the brain. Yet Bergson argued that this very question, “Is experience stored in the brain?” is the critical issue in the problem of consciousness. His examination of then-current memory research led him, save for motor or procedural memory, to a “no” answer. Others, for example Sheldrake, have continued this negative assessment of the research findings. So, has this assumption actually been (...) proven since Bergson? Do we know how experience is stored? Or that it is stored? Here, a recent review and model of memory is examined to see where this assumption actually stands. Again, the assessment will be that nothing has changed. The core of the problem, it will be argued, lies in two things: Firstly, the search for how/where experience is stored is motivated—rephrasing Bergson—in the classic metaphysic, a framework on space and time whose logic cannot be coherently, logically adhered to in attempting to explain how experience is stored. Secondly, the search generally assumes an inadequate theory of perception that is implicitly based in this classic metaphysic. If framed within Bergson’s model of perception and his temporal metaphysic, conjoined with J. J. Gibson’s model, the storage-search appears misguided from the start. (shrink)

Building on organizational justice research, we extended the study of classroom justice to management education. In the first study, we identified the criteria that business students use to define distributive, procedural, and interactional fairness. In a second study, we found that management students? perceptions of both procedural and interactional fairness were significant and unique predictors of their evaluations of instructional effectiveness. However, procedural justice was the only significant predictor of overall evaluations of the course. Results of this study will aid (...) management educators in implementing procedures and treatment that students perceive as fair and also to serve as ethical role models for managers of the future. (shrink)

For this 1897 publication, the American philosopher William James brought together ten essays, some of which were originally talks given to Ivy League societies. Accessible to a broader audience, these non-technical essays illustrate the author's pragmatic approach to belief and morality, arguing for faith and action in spite of uncertainty. James thought his audiences suffered 'paralysis of their native capacity for faith' while awaiting scientific grounds for belief. His response consisted in an attitude of 'radical empiricism', which deals (...) practically rather than ideologically with real-world phenomena. When facing a 'momentous' decision about belief, he says, we both can and must choose the best hypothesis. The first four essays apply this principle to religious faith, and the rest explore the pragmatic approach to such topics as determinism, ethics and individual achievement. James developed his ideas further in The Varieties of Religious Experience and Pragmatism, both of which are reissued in this series. (shrink)