We use a creature construction to show that consistently $$\begin{aligned} \mathfrak d=\aleph _1= {{\mathrm{cov}}}< {{\mathrm{non}}}< {{\mathrm{non}}}< {{\mathrm{cof}}} < 2^{\aleph _0}. \end{aligned}$$The same method shows the consistency of $$\begin{aligned} \mathfrak d=\aleph _1= {{\mathrm{cov}}}< {{\mathrm{non}}}< {{\mathrm{non}}}< {{\mathrm{cof}}} < 2^{\aleph _0}. \end{aligned}$$.

Aworkshop was held August 26–28, 2015, by the Earth- Life Science Institute (ELSI) Origins Network (EON, see Appendix I) at the Tokyo Institute of Technology. This meeting gathered a diverse group of around 40 scholars researching the origins of life (OoL) from various perspectives with the intent to find common ground, identify key questions and investigations for progress, and guide EON by suggesting a roadmap of activities. Specific challenges that the attendees were encouraged to address included the following: What key (...) questions, ideas, and investigations should the OoL research community address in the near and long term? How can this community better organize itself and prioritize its efforts? What roles can particular subfields play, and what can ELSI and EON do to facilitate research progress? (See also Appendix II.) The present document is a product of that workshop; a white paper that serves as a record of the discussion that took place and a guide and stimulus to the solution of the most urgent and important issues in the study of the OoL. This paper is not intended to be comprehensive or a balanced representation of the opinions of the entire OoL research community. It is intended to present a number of important position statements that contain many aspirational goals and suggestions as to how progress can be made in understanding the OoL. The key role played in the field by current societies and recurring meetings over the past many decades is fully acknowledged, including the International Society for the Study of the Origin of Life (ISSOL) and its official journal Origins of Life and Evolution of Biospheres, as well as the International Society for Artificial Life (ISAL). (shrink)

Converse in the Spirit is a comparative study of the writings of William Blake and the German visionary philosopher Jacob Boehme. It argues that the relationship between Blake and Boehme was a meeting of like minds that transcended place and time, that each regarded himself as part of a community of vision, and aspiration, and believed that any predominant form ofthought and understanding was only partial.

Geist und Natur im Widerspruch und in der Übereinstimmung.--Das Menschenbild im Lichte der Heilkunde.--Roger Bacon (1214[?]-1292) und Nicolaus Cusanus (1401-1464) als Begründer chemischer und physikalisch-chemischer Methoden in der Medizin.--Leonardo da Vinci als Physiologe.--Die kosmologische Anthropologie des Paracelsus als Grundlage seiner Medizin.--Konrad Gessner (1516-1567).--Johann Jakob Scheuchzer (1672-1733).--Goethe und die wissenschaftliche Medizin seiner Zeit.--Die Krankheitsauffassung Friedrich von Hardenbergs (Novalis).--Rudolf Kassner.--Anmerkungen (p. [285]).

Jakob Friedrich Fries (1773–1843) was a nineteenth-century German philosopher, contemporaneous with so-called “German Idealism,” who is best known for his main work, New Critique of Reason (1807/1828–1831).¹ Fries regards Kant’s philosophy as incomplete and tries to revise and renew it. Since he adopts Kant’s spirit of criticism, he emphasises the finitude of human cognition and in this respect he criticises his contemporaneous opponents: Reinhold, Fichte, and Schelling. Fries criticises Kant’s conception of transcendental cognition as follows: Although transcendental cognition concerns (...) cognitions a priori, transcendental cognition itself can be acquired only in an empirical way because human cognition always begins with experience. Hence Kant was in error to regard it as a priori. German Idealists elaborated on Kant’s mistake and interpreted mere inner perception as cognition a priori, which led them to adopt the “synthetic method” as a means of philosophising. Fries corrects them by assuming the “analytical method,” whereby he starts from the standpoint of ordinary experience by analysing “the ordinary opinions (Beurtheilungen) in daily life” in order to reveal the philosophical cognitions constructing the general presuppositions of opinions. He calls such a project “Critique of Reason.” Kuno Fischer (1824–1907), however, contradicts Fries’s approach by defending German Idealists, arguing that the cognition a priori can never be acquired in an empirical way. Otto Liebmann (1840 –1912) also follows Fischer and criticises Fries’s approach as a “retrogression to Locke.” In this article I deal with Fries’s conception of the “Critique of Reason” and respond to the objections above. Fries’s method is an analysis of opinions, which are neither mere experience nor logical judging (urtheilen). The philosophical cognitions constructing the presuppositions of opinions belong to “reason,” which is to be distinguished from “understanding,” which conducts the “analysing” operation by relying on arbitrary reflection. (shrink)

Jakob Friedrich Fries is one of the most important representatives of the Critical Philosophy, someone who built immediately on the original Kantian philosophy. -/- Fries was born in 1773 in Barby (on the Elbe). In 1805 he was extraordinary professor for philosophy in Jena and in the same year was ordinary professor for philosophy in Heidelberg. Returning to Jena in 1816, one year later he was compulsorily retired because of his participation at the nationalistic and republican Wartburg Festival. In (...) 1924 he obtained a professorship for physics and mathematics, and in 1838 he was given back a professorship for philosophy. He died in 1843 in Jena. -/- The book summarizes the research results of the DFG-Project "Jakob Friedrich Fries' Influence on the Sciences of the 19th Century". The research project was carried out by Dr. Kay Herrmann (Institute of Philosophy, Jena University) and Prof. Dr. Wolfram Hogrebe (Institute of Philosophy, Bonn University). Such a study has special importance. There is available a large amount of literature about the "speculative contemporaries" of Fries, like Fichte, Schelling, and Hegel. In contrast to the "speculative philosophy", there has been published only a few studies about the Friesian natural philosophy. Fries was, in his natural-philosophical studies, looking for a link between philosophy and modern sciences, wheras his "speculative philosophical" contemporaries felt obligated to stick primarily to a descriptive, phenomenal view of nature. So far the question "How was mathematical natural philosophy regarded by scientists and mathematicians of the 19th century?" has hardly been investigated. Archival studies showed that this gap in Fries-research can be filled. The Friesian correspondence turned out to be a rich gold mine. -/- The present publication is more than a research report. The monographic first part is intended to introduce the foundations of the Friesian theory of cognition, the Friesian methodology, and the Friesian natural philosophy. This should facilitate entry into Friesian philosophy. -/- The Friesian theory is analyzed from two points of view: •How did Fries suceed in continuing and improving the Kantian approach? Is Fries able to remove the weak points of Kantian philosophy? -/- •What is the current significance of the Friesian approach? There are some interesting similarities between the Friesian approach and modern philosophical theories (such like Chomsky's theory of "universal grammer"). The lasting core of the Friesian theory of cognition is: To use empirical studies for working on philosophical problems. -/- Chapters 3 and 4 are scientific-historically oriented. These chapters analyze the Friesian position in scientific and mathematical debates (debates about the a priori foundations of physics, the problem of the identification of physics as an independent discipline, the problem of the boundary between chemistry and physics, the problem of mathematization of the sciences, the theory of the imponderabilia, the systematics and structure of sciences and mathematics, problems of infinity, the differential calculus, the theory of parallel lines) and the relation between Fries and the scientists of the 19th century. The book contains the latest findings gained by evaluation of the Friesian unpublished work (for example the correspondence with W. Weber, C. F. Gauß, E. F. Apelt, O. Schlömilch, Ch. Reichel, B. A. v. Lindenau, L. Gmelin, E. G. Fischer, A. N. Scherer, J. S. C. Schweigger) -/- One result of the research project is that some important scientists took a favourable view of the Friesian theory, but the influence of the Friesian philosophy on the sciences of the 19th century was very limited. The causes are very complex: An anti-natural-philosophical spirit of age, the limits of the Kantian inspired philosophy and some unfavourable aspects in the biography of Fries. -/- For the first time the voluminous Fries-Reichel-correspondence was evaluated. The Fries-Reichel-correspondence contains the Friesian approach to prove the 11th Euclidean axiom, and the whole transcript of the Friesian attempt at proof is given. // Der erste Teil des Buches will in die Grundprobleme Fries’scher Erkenntnis­theorie, Methodenlehre und Naturphilosophie einführen, wobei das Hauptaugenmerk auf die Fortführung der kantischen Ansätze durch Fries sowie auf die aktuelle Interpretation der Fries’schen Lehre gerichtet ist. Der wissenschaftshistorisch ausgerichtete zweite Teil analysiert Fries’ Stellung zu naturwissenschaftlichen und mathematischen Diskussionsrichtungen (Probleme der Identifizierung der Physik als eigenständige Disziplin, der Grenzziehung zwischen Physik und Chemie, der Mathematisierung der Naturwissenschaften, der Imponderabilientheorie, der Systematik von Naturwissenschaft und Mathematik, des Unendlichen, der Parallelentheorie usw.) sowie sein Verhältnis zu Naturwissenschaftlern und Mathematikern seiner Zeit. Das Buch enthält neue Erkenntnisse, die aus der Auswertung zahlreicher Nachlassmaterialien gewonnen wurden. Erstmalig wird unter dem Blickwinkel „Fries als Naturwissenschaftler und Mathematiker“ auch der sehr umfangreiche Reichel-Briefwechsel ausgewertet. Dem Reichel-Briefwechsel entstammt auch Fries’ Versuch eines Beweises des Parallelenaxioms, der in diesem Buch erstmalig in transkribierter Form vollständig vorliegt. -/- . (shrink)

This article discusses the phenomenon of normative resilience, with a focus on evaluative resilience. An object can become more or less valuable. In addition to this change in an object's value, the object's value can become more or less resilient. If it is less resilient, it cannot withstand as much evaluative change without its degree of value changing, as compared to an object with more resilient value. The article consists of three parts. First, examples of resilience are presented to give (...) the reader an intuitive understanding of the phenomenon, Second, the Fitting Attitudes Analysis of value is invoked to provide a formal account of evaluative resilience. Third, the theoretical and practical advantages of acknowledging the existence of evaluative resilience are brought to light. (shrink)

Swedish beef and dairy farmers are currently facing a challenging financial situation. Simultaneously, beef farming contributes significant environmental impacts. To support farmers, actors from the whole value chain are now promoting Swedish beef as particularly ‘sustainable’. The paper draws on critical discourse analysis of interviews with and documents from the largest Swedish supermarket chain ICA, Swedish farmer organisations and farmers to study how ICA and farmers articulate sustainability and their responsibility for the same. Articulations are subsequently discussed in the light (...) of actual environmental impacts of beef production and the distribution of power in the beef value chain. The findings suggest that negative environmental impacts and farmers’ struggles are largely hidden in the dominant articulation of sustainability. Furthermore, ICA does not use the power it has to steer consumers toward reduced beef consumption. We conclude with suggesting more open deliberation about current levels of beef sales and consumption and about what compromises to make when striving for ‘sustainable’ beef consumption. (shrink)

Early embryogenesis is marked by a frail Spindle Assembly Checkpoint (SAC). The time of SAC acquisition varies depending on the species, cell size or a yet to be uncovered developmental timer. This means that for a specific number of divisions, biorientation of sister chromatids occurs unsupervised. When error‐prone segregation is an issue, an aneuploidy‐selective apoptosis system can come into play to eliminate chromosomally unbalanced cells resulting in healthy newborns. However, aneuploidy content can be too great to overcome, endangering viability.SAC generates (...) a diffusible signal to lengthen time spent in mitosis if needed, ensuring correct chromosome segregation, a fundamental factor in the generation of euploid cells. Thus, it remains puzzling what benefit could come from delaying SAC acquisition till later in the development. In this review, we describe what is known on SAC acquisition in distinct species and highlight pending research as well as potential applications for such knowledge. (shrink)

What are the underlying processes that enable human beings to recognize a happy face? Clearly, featural and configural cues will help to identify the distinctive smile. In addition, the motivational state of the observer will influence the interpretation of emotional expressions. Therefore, a model accounting for emotion recognition is only complete if bottom-up and top-down aspects are integrated.

Questions about the validity of eye fixations in the blocks task as a memory indicator are discussed. Examples from reading research illustrate the influence of extraneous factors.

Der Band zeichnet Kants Weg zur kritischen Ausarbeitung der Gottesfrage nach, reflektiert seinen Übergang von der Physikotheologie zur Ethikotheologie und bedenkt den Zusammenhang von Kants Kritik der Theologie und seinem Gottespostulat. Der Gottesbegriff in Kants "Religionsschrift" wird ebenso durchleuchtet wie die Beziehung zwischen philosophischer Gotteslehre und Offenbarungstheologie sowie die trinitätstheologischen Ansätze in Kants Philosophie.

There has been endless debate about the exchanges regarding the relation of divine love and piety in Plato’s Euthyphro. This debate has mostly missed what is truly puzzling about these exchanges—and hence the import of the dialogue as a whole—which is why Socrates is able to refute Euthyphro, the man. What is particularly puzzling is why Euthyphro accepts the suggestion that leads to his refutation. In answering this question by analyzing the drama of the dialogue, I discuss the deeper issue (...) in the dialogue—the significance and nature of human autonomy. (shrink)

CASUS is an authoring system, which should enable physicians to produce problem-based computer learning programs with minimal technical effort and give them sound instructional support. The theoretical background of CASUS are constructivist approaches to learning and instruction, which deal mainly with the question, how to design problem-based learning environments. The paper presents the constructivist concept of CASUS and results of a forma-tive evaluation. Four authors were observed and interviewed while developing a learning case with CASUS. The evaluation pursued mainly the (...) question of which difficulties arise while producing a case with CASUS and which measures are necessary in order to improve the authoring system. Results show that with regard to technical aspects physicians can produce learning cases even without any special prior knowledge. There were far more problems with instructional aspects of the production of cases. Most of these difficulties were very specific to the content of the cases. Therefore, it seems that an appropriate way to design learning cases with high quality, is a cooperation between some authors with different expertise. (shrink)

Motivated by recent results and questions of Raghavan and Shelah, we present ZFC theorems on the bounding and various almost disjointness numbers, as well as on reaping and dominating families on uncountable, regular cardinals. We show that if $\kappa =\lambda ^+$ for some $\lambda \geq \omega $ and $\mathfrak {b}=\kappa ^+$ then $\mathfrak {a}_e=\mathfrak {a}_p=\kappa ^+$. If, additionally, $2^{<\lambda }=\lambda $ then $\mathfrak {a}_g=\kappa ^+$ as well. Furthermore, we prove a variety of new bounds for $\mathfrak {d}$ in terms of (...) $\mathfrak {r}$, including $\mathfrak {d}\leq \mathfrak {r}_\sigma \leq \operatorname {\mathrm {cf}}]^\omega )$, and $\mathfrak {d}\leq \mathfrak {r}$ whenever $\mathfrak {r}<\mathfrak {b}^{+\kappa }$ or $\operatorname {\mathrm {cf}})\leq \kappa $ holds. (shrink)

We study \(\kappa \) -maximal cofinitary groups for \(\kappa \) regular uncountable, \(\kappa = \kappa ^{. Revisiting earlier work of Kastermans and building upon a recently obtained higher analogue of Bell’s theorem, we show that: Any \(\kappa \) -maximal cofinitary group has \({ many orbits under the natural group action of \(S(\kappa )\) on \(\kappa \). If \(\mathfrak {p}(\kappa ) = 2^\kappa \) then any partition of \(\kappa \) into less than \(\kappa \) many sets can be realized as the (...) orbits of a \(\kappa \) -maximal cofinitary group. For any regular \(\lambda > \kappa \) it is consistent that there is a \(\kappa \) -maximal cofinitary group which is universal for groups of size \({. If we only require the group to be universal for groups of size \(\kappa \) then this follows from \(\mathfrak {p}(\kappa ) = 2^\kappa \). (shrink)