Purified nuclei are being used as a test system to study the regulation of nuclear enzymes in plants. Regulatory agents such as light, hormones and polyamines can stimulate kinases or phosphatases that control nuclear protein phosphorylation and they can modulate the activity of as yet unidentified enzymes required for transcript synthesis and/or stabilization. This essay summarizes current findings and discusses the advantages and pitfalls of using isolated nuclei to investigate how nuclear functions are controlled.

A study was undertaken of the views of users of two genitourinary medicine (GUM) clinics in England on unlinked anonymous testing (UAT) for HIV. The UAT programme measures the prevalence of HIV in the population, including undiagnosed prevalence, by testing residual blood (from samples taken for clinical purposes) which is anonymised and irreversibly unlinked from the source. 424 clinic users completed an anonymous questionnaire about their knowledge of, and attitudes towards, UAT. Only 1/7 (14%) were aware that blood left over (...) from clinical testing may be tested anonymously for HIV. A large majority (89%) said they would agree to their blood being tested, although 74% wanted the opportunity to consent. These findings indicate broad support for UAT of blood in a group of patients whose samples are included in the HIV surveillance programme. The findings suggest the need for greater attention to be given to the provision of information and, if replicated in a larger survey, may justify a reappraisal of UK policy on UAT. (shrink)

The analysis of the measurement of gravitational fields leads to the Rosenfeld inequalities. They say that, as an implication of the equivalence of the inertial and passive gravitational masses of the test body, the metric cannot be attributed to an operator that is defined in the frame of a local canonical quantum field theory. This is true for any theory containing a metric, independently of the geometric framework under consideration and the way one introduces the metric in it. Thus, to (...) establish a local quantum field theory of gravity one has to transit to non-Riemann geometry that contains (beside or instead of the metric) other geometric quantities. From this view, we discuss a Riemann–Cartan and an affine model of gravity and show them to be promising candidates of a theory of canonical quantum gravity. (shrink)

The analysis of the measurement of gravitational fields leads to the Rosenfeld inequalities. They say that, as an implication of the equivalence of the inertial and passive gravitational masses of the test body, the metric cannot be attributed to an operator that is defined in the frame of a local canonical quantum field theory. This is true for any theory containing a metric, independently of the geometric framework under consideration and the way one introduces the metric in it. Thus, to (...) establish a local quantum field theory of gravity one has to transit to non-Riemann geometry that contains (beside or instead of the metric) other geometric quantities. From this view, we discuss a Riemann–Cartan and an affine model of gravity and show them to be promising candidates of a theory of canonical quantum gravity. (shrink)

Nowadays, essentialism has obtained various senses and its extension reaches out over many branches of study who have some immediate connection with it. Socrates, Plato, Aristotle, Saul Kripke, Hilary Putnam and David Wiggins are the notable upholders of essentialism. The Essentialist movement which stemmed from the view that philosophy is a speculative study of Reality was temporarily suspended or stagnated by the spirited movement of the logical positivists like Moritz Schlick, Hans Reichenbach, Rudolf Carnap and A. J. Ayer. According to (...) these philosophers, philosophy is simply an activity of analysis of the fundamental concepts of ordinary language or of science or of any other discipline. Such concept—analysis—philosophers are called anti-essentialist. Here, I shall concentrate on the views of Aristotle. I shall discuss the doctrine of essence, natural kinds, real essence in favour of essentialism and also discuss W. V. O. Quine’s view as an anti-essentialist trend. At last I shall try to examine whether and to what extent an attack of essences reflects back certain essentialist commitments, which is to see what reasonable theory of essences can be eked out from the entire exercise. (shrink)

An important book. This Festschrift presented to Professor Datta on the occasion of his 70 birthday, contains important contributions by a number of non-Eastern philosophers, including Edwin A. Burtt, "A Problem in Comparative Philosophy," William K. Frankena, "Ethics in an Age of Science," Cornelius Kruse, "Immanuel Kant," F. S. C. Northrop, "The Philosophical Roots and Validity of Tagore's Genius," and H. W. Schneider's, "Religious Diversity in America." Dr. D. M. Datta was both a scholarly and professional philosopher, as (...) well as a colleague of Gandhi in India's nonviolent struggle for freedom.--W. A. J. (shrink)

This is a reply to R. P. Datta, J. Frauley and F. Pearce, ‘Situation critical: for a critical, reflexive, realist, emancipatory social science’ (Journal of Critical Realism 9(2) 2010: 229–48), which responded to my critique in ‘“Orthodox critical realism” and the critical realist embrace’ (Journal of Critical Realism 8(3): 233–57) of J. Frauley and F. Pearce, eds, Critical Realism and the Social Sciences: Heterodox Elaborations (Toronto: University of Toronto Press).

1. Premadharma o Rāsalīlā.-- 2. Bedānta o bijñāna ebaṃ Jagadgurura ābirbhāba.-- 3. Upanishad-brahmatattva ebaṃ yājñabalkyera advaitabāda.-- 4. Upanishad-jaṛa o jībatattva.-- 5. Karmabāda o janmāntara, abatāratattva ebaṃ prakr̥ta yoga ki? -- v. 6. Sāṃkhya paricaẏa, Buddhadebera 'nāstikatā' ebaṃ buddhi o bodhi. -- v. 7. Gītāẏa Īśvarabāda, Raṅgamatī, ebaṃ Meghadūta (mūla o padyānubāda).

Transcript of speeches by a Hindu philosopher, chiefly on Hindu philosophy and Hinduism.

The governments of China, India, and the United Kingdom are unanimous in their belief that bioinformatics should supply the link between basic life sciences research and its translation into health benefits for the population and the economy. Yet at the same time, as ambitious states vying for position in the future global bioeconomy they differ considerably in the strategies adopted in pursuit of this goal. At the heart of these differences lies the interaction between epistemic change within the scientific community (...) itself and the apparatus of the state. Drawing on desk-based research and thirty-two interviews with scientists and policy makers in the three countries, this article analyzes the politics that shape this interaction. From this analysis emerges an understanding of the variable capacities of different kinds of states and political systems to work with science in harnessing the potential of new epistemic territories in global life sciences innovation. (shrink)

The paper discusses anumāna and its variety in general from the point of view of inferential cognition for the sake of oneself as well as for the sake of others; i.e. svārthānumāna and parārthānumāna as given in the Buddhist tradition of logic, especially with parārthānumāna, its nature and role. The paper argues that the Buddhist intent of division of anumāna into svārthānumāna and parārthānumāna was to bring Buddha-vacanas under the category of parārthānumāna and to save them from being classified under (...) śabda pramāṇa. It contends that such a division was not just an epistemological demand, but had a deeper philosophical significance in the Buddhist conceptual framework. Such a division is, therefore, intended to reject the role of śabda as an extra causal means or pramāṇa. The paper identifies the logical commitment in Buddhist tradition as hetu-centric commitment as it differs from the Nyāya tradition of vyāpti-centric one. (shrink)

Background: Informed consent in the modern era is a common and important topic both for the well-informed patient and to prevent unnecessary litigation. However, the effectiveness of informed consent in trauma patients is an under-researched area. This paper aims to assess the differences in patient recall of the consent process and desire for information by performing a comparative analysis between orthopaedic trauma and elective patients. Methods: Information from 41 consecutive elective operations and 40 consecutive trauma operations was collected on the (...) first post-operative day. Results: 100% of elective patients and 90% of trauma patients knew what operation they had received (p = 0.06). Overall recall of complications was poor, but was significantly lower in trauma patients compared with elective patients (62% vs 22%, p<0.001). 30% of trauma patients desired more information about their operation compared to 12% of elective patients (p = 0.049), although only 35% of trauma patients wanted written as well as verbal explanations, compared to 85% of elective patients p<0.001). Overall 100% of elective and 90% of trauma patients were happy with the consent process (p = 0.06). Subset analysis of neck of femur compared to other trauma patients showed that the above factors were not significantly different between the two groups. Conclusions: Recall of complications in the trauma patients is significantly lower than in elective patients, although both groups scored poorly overall. Repeated verbal explanations should be reinforced with the option of additional information leaflets for trauma operations. Further research into the usefulness of DVDs for commonly performed operations is warranted, although official internet resources may be more cost-effective. (shrink)

This paper articulates the commitments, contours and justifications for a pluralist but non-eclectic critical, realist, reflexive social science with emancipatory aims. In it, we stress that social science can and should be used to guide the conceptualization of desirable and viable forms of social organization and their conditions of realization. In this regard, we advocate explanatory theorizing as an ethical duty of social scientists and as a moral good in itself as well as being an inherent epistemological component of scientific (...) practice. This entails that we take seriously the research strategies apposite to our disciplinary, intertextual and interdiscursive locations to make a serious theoretical case and practical case for the kind of social science here advocated. In our view, such a social science must acknowledge the path-breaking work of Roy Bhaskar, but must also recognize that the arguments deployed in texts as a resource in intellectual work can never be treated as the axiomatic grounds for further thought, but must be interrogated thoroughly and in each case what is to be retained must be defensible. No position has a monopoly of relevant insights and the development of science often involves syntheses. Syntheses must not be syncretic but reflexively interrogated to assess epistemological, ontological and conceptual coherence to avoid eclecticism. Development in critical realist philosophy will, we believe, continue to confront and offer plausible resolutions to a range of battles within and pertinent to philosophy and social-scientific metatheory. However, realists must recognize the continuing importance and discursive effects of a variety of critical and realist work in being able to defend, sustain and develop rigorous social-scientific research with emancipatory commitments. (shrink)

Consequence is at the heart of logic, and an account of consequence offers a vital tool in the evaluation of arguments. This text presents what the authors term as 'logical pluralism' arguing that the notion of logical consequence doesn't pin down one deductive consequence relation; it allows for many of them.

Study on Upanishads and commentaries of Śaṅkarācārya, Hindu philosopher, on it.

Collection of lectures on Hindu philosophy, religion, and culture of India.

How does one decolonize and reclaim the meanings of research and researcher, particularly in the context of Western research? Indigenous communities have long experienced oppression by Western researchers. Is it possible to build a collaborative research knowledge that is culturally appropriate, respectful, honoring, and careful of the Indigenous community? What are the challenges in Western research, researchers, and Western university methodology research training? How have ‘studies’ – critical anti-racist theory and practice, cross-cultural research methodology, critical perspectives on environmental justice, and (...) land-based education – been incorporated into the university to disallow dissent? What can be done against this disallowance? According to Eve Tuck and K Wayne Yang’s suggestion, this article did not use the concept of decolonization as a substitute for ‘human rights’ or ‘social justice’, but as a demand of an Indigenous framework and a centering of Indigenous land, Indigenous sovereign... (shrink)

The microfinance business model focuses largely on lending to the woman in the household, rather than the man. The belief is that women are more trustworthy borrowers than men, and that lending to women may have increased social impact. Yet in several cases, women do not have control over the loan backed business despite being the borrower of record. Such takeover of the business by the man constitutes an ethical violation. We find that high dependency ratios in the family are (...) correlates of such ethical violations. Further, we also find that ethical violations have a significant economic cost, consistent with prior scholarship in the family-business domain. While access to microfinance increases household welfare, this beneficial impact reduces by over 50% in the presence of an ethical violation. Our results suggest that microfinance lenders need to move beyond the traditional role of just being a lender to providing advice on issues like family planning, and money management, and enforcement, thus moving closer to the solidarity economy paradigm of integrating savings and credit into broader canvases of social relationships and social structures. (shrink)

Providing an original and systematic treatment of foundational issues in philosophy of religion, J. L. Schellenberg's new book addresses the structure of..

Articles chiefly on the Bratachāri Movement, founded and popularised by Gurusadaẏa Datta, 1882-1941; includes articles on nationalism with special reference to Bengal, India.

What happens when someone acts? A familiar answer goes like this. There is something that the agent wants, and there is an action that he believes conducive to its attainment. His desire for the end, and his belief in the action as a means, justify taking the action, and they jointly cause an intention to take it, which in turn causes the corresponding movements of the agent's body. I think that the standard story is flawed in several respects. The flaw (...) that will concern me in this paper is that the story fails to include an agent-or, more precisely, fails to cast the agent in his proper role. (shrink)

On 27 February 1998, the Indian Institute of Management, Calcutta and the office of the Fulbright binational educational exchanges in Calcutta jointly hosted a seminar on 'The Tradition of Non Violence: The American Experience and the Gandhian' at the Management Centre for Human Values. There were two keynote presentations. The one on the American experience was by Michael True, Professor of English Literature at Assumption College, Massachusetts, who was teaching as Fulbright visiting lecturer at Utkal University, Bhubaneswar. The Gandhian case (...) was presented by Profes sor Amlan Datta, economist and writer, also former Vice-Chancellor of Visva-Bharati University, Santiniketan. The session was chaired by Professor Amitava Bose, Director, Indian Institute of Management. To close the discussions, a summing up was presented by Professor S.K. Chakraborty, Convenor, Management Centre for Human Values. The importance of discussions on the subject of non-violence and the Gandhian alterna tive cannot be overestimated in this year of the 50th anniversary of Indian independence and a nationwide soul-searching over these five decades. The US Educational Foundation in India contributed to the national discussion through this bilateral seminar and its comparative perspective. (shrink)

On the concept of self; study based on Vedic literature.