BackgroundLarge-scale, centralized data repositories are playing a critical and unprecedented role in fostering innovative health research, leading to new opportunities as well as dilemmas for the medical sciences. Uncovering the reasons as to why citizens do or do not contribute to such repositories, for example, to population-based biobanks, is therefore crucial. We investigated and compared the views of existing participants and non-participants on contributing to large-scale, centralized health research data repositories with those of ex-participants regarding the decision to end their (...) participation. This comparison could yield new insights into motives of participation and non-participation, in particular the behavioural change of withdrawal.MethodsWe conducted 36 in-depth interviews with ex-participants, participants, and non-participants of a three-generation, population-based biobank in the Netherlands. The interviews focused on the respondents’ decision-making processes relating to their participation in a large-scale, centralized repository for health research data.ResultsThe decision of participants and non-participants to contribute to the biobank was motivated by a desire to help others. Whereas participants perceived only benefits relating to their participation and were unconcerned about potential risks, non-participants and ex-participants raised concerns about the threat of large-scale, centralized public data repositories and public institutes, such as social exclusion or commercialization. Our analysis of ex-participants’ perceptions suggests that intrapersonal characteristics, such as levels of trust in society, participation conceived as a social norm, and basic societal values account for differences between participants and non-participants.ConclusionsOur findings indicate the fluidity of motives centring on helping others in decisions to participate in large-scale, centralized health research data repositories. Efforts to improve participation should focus on enhancing the trustworthiness of such data repositories and developing layered strategies for communication with participants and with the public. Accordingly, personalized approaches for recruiting participants and transmitting information along with appropriate regulatory frameworks are required, which have important implications for current data management and informed consent procedures. (shrink)

Some people claim that evolution is "just a theory". Do you know what a scientific theory really is? Just a theory is an overview of the modern concepts of science. A clear understanding of the nature of science will enable you to distinguish science from pseudoscience (which illegitimately wraps itself in the mantle of science), and real social issues in science from the caricatures portrayed in postmodernist critiques. Prof. Ben-Ari's style is light (even humorous) and easy to read, bringing the (...) latest concepts of science to the general reader. Of particular interest is his analysis of the terminology of science (fact, law, proof, theory) in relation to the colloquial meaning of these terms. Between chapters are biographical vignettes of scientists — both familiar and unfamiliar — showing their common commitment to the enterprise of science, together with a diversity of backgrounds and personalities. This accessible, informative, and comprehensive work will give lay readers a good grasp of real science. (shrink)

Charles Taber and Milton Lodge provide compelling evidence that people's minds may be closed to information that is inconsistent with their prior beliefs. This type of inconsistency has often been termed ?irrational.? However, recent research suggests that being open or closed minded is not an unchanging variable but depends on one's goals, including one's need for closure, which vary from person to person and situation to situation. In this vein, as Taber and Lodge suggest, those who have more political information (...) may, after having been open minded enough to acquire the information, become closed minded by virtue of having acquired it. At the same time, being more open minded to inaccurate information might lead one in the wrong direction; hence, open mindedness does not necessarily enhance the accuracy of one's judgments or the quality of one's decisions. We may need to rethink the concept of an enlightened, well-informed electorate, to the extent that it assumes the unqualified benefits of open mindedness. (shrink)

Machine generated contents note: -- Explaining the Liberal Predicament * PART I: The Importance of Being Witty * A Young Boy from Riga * Becoming a Russian-Jew * The Realist Appeal * PART II: The Pink Liberal * Mr. Jericho's Piercing Eyes * 'I Never Don't Moralize' * Karl Marx * PART III: The Anti-Cosmopolitan Pluralist * Collisions * On Moses and Joshua * Shifting Horizons * 'This mighty conflict between the fantasy of Home and the fantasy of Away'.

Mathematical Logic for Computer Science is a mathematics textbook with theorems and proofs, but the choice of topics has been guided by the needs of computer science students. The method of semantic tableaux provides an elegant way to teach logic that is both theoretically sound and yet sufficiently elementary for undergraduates. To provide a balanced treatment of logic, tableaux are related to deductive proof systems.The logical systems presented are:- Propositional calculus (including binary decision diagrams);- Predicate calculus;- Resolution;- Hoare logic;- Z;- (...) Temporal logic.Answers to exercises (for instructors only) as well as Prolog source code for algorithms may be found via the Springer London web site: http://www.springer.com/978-1-85233-319-5 Mordechai Ben-Ari is an associate professor in the Department of Science Teaching of the Weizmann Institute of Science. He is the author of numerous textbooks on concurrency, programming languages and logic, and has developed software tools for teaching concurrency. In 2004, Ben-Ari received the ACM/SIGCSE Award for Outstanding Contributions to Computer Science Education. (shrink)

Reflections on Seyla Benhabib’s a. Exile, Statelessness, and Migration: Playing Chess with History from Hannah Arendt to Isaiah Berlin. Princeton, NJ: Princeton University Press, 2018.

This article presents a paradox in the thought of Edith Stein betweenher attitudes in relation to the state/law problem and her vision ofreligion. I seek to explain the paradox through the study of the Theoryof the State and Sovereignty. In this regard, basing herself onclassical authors, Edith Stein disagrees with the great jurists of hertime who did not always recognise the priority of the concept ofsovereignty. The examination of the relationship between the State andlaw breaks new ground within her phenomenological (...) position, by, on theone hand, defending a strong concept of sovereignty of the State seen asa legal a priori while on the other hand stating that the State doesn'trelate to spiritual values. This leads us to propose a particular viewof the semiotic processes relevant to the relation between law/stateand religion, illuminating the semantic-pragmatic factors which promptedStein towards the above contradiction. (shrink)

The contributions in this volume treat aspects and manifestations of this cultural symbiosis, and they throw new light on authors and texts both more and less ...

The rise of quantum information theory has lent new relevance to experimental tests for non-classicality, particularly in controversial cases such as adiabatic quantum computing superconducting circuits. The Leggett-Garg inequality is a “Bell inequality in time” designed to indicate whether a single quantum system behaves in a macrorealistic fashion. Unfortunately, a violation of the inequality can only show that the system is either (i) non-macrorealistic or (ii) macrorealistic but subjected to a measurement technique that happens to disturb the system. The “clumsiness” (...) loophole (ii) provides reliable refuge for the stubborn macrorealist, who can invoke it to brand recent experimental and theoretical work on the Leggett-Garg test inconclusive. Here, we present a revised Leggett-Garg protocol that permits one to conclude that a system is either (i) non-macrorealistic or (ii) macrorealistic but with the property that two seemingly non-invasive measurements can somehow collude and strongly disturb the system. By providing an explicit check of the invasiveness of the measurements, the protocol replaces the clumsiness loophole with a significantly smaller “collusion” loophole. (shrink)

v. 1. Philosophy, theology and mysticism in medieval Islam -- v. 2. Early Islamic theology : the Muʻtazilites and al-Ashʻarī -- v. 3. Classical Islamic theology : the Ashʻarites.