ARAGÃO, Ivan Rêgo. “ Vinde todas as pessoas, e vede a minha dor ”: A Festa/Procissão ao Nosso Senhor dos Passos como Atrativo Potencial Turístico em São Cristóvão-Sergipe-Brasil. 2012. 198f. Dissertação (Mestrado) Cultura e Turismo – Universidade Estadual de Santa Cruz (UESC), Ilhéus-BA. Palavras-chave: Turismo Cultural-Religioso Católico. Religiosidade Popular. Festa do Senhor dos Passos. Keywords: Catholic Religious-Cultural Tourism. Popular Religiosity. Party of Lord of the Steps.
Stem cell biology and systems biology are two prominent new approaches to studying cell development. In stem cell biology, the predominant method is experimental manipulation of concrete cells and tissues. Systems biology, in contrast, emphasizes mathematical modeling of cellular systems. For scientists and philosophers interested in development, an important question arises: how should the two approaches relate? This essay proposes an answer, using the model of Waddington’s landscape to triangulate between stem cell and systems approaches. This simple abstract model (...) represents development as an undulating surface of hills and valleys. Originally constructed by C. H. Waddington to visually explicate an integrated theory of genetics, development and evolution, the landscape model can play an updated unificatory role. I examine this model’s structure, representational assumptions, and uses in all three contexts, and argue that explanations of cell development require both mathematical models and concrete experiments. On this view, the two approaches are interdependent, with mathematical models playing a crucial but circumscribed role in explanations of cell development. (shrink)
Every Christian who carefully reads the message of St. Apostle Paul, can not do it pay attention to the number of times he uses, so to speak, military terminology. Suffice it to read the sixth chapter of the epistle to the Ephesians - the words, which is also St. Mr. Patriarch Joseph finished his Testament: "Fix in the Lord and in the power of his power. Put on a full armor of God so that you can resist the tricks devilish (...) For we have to fight not against the body and blood, but against the beginning, against the authorities, against the rulers of this world of darkness, against the spirits of malice Therefore, take a full weapon God so that you can resist and... stand firmly. Stand, then, girth Your hips are right, putting on the armor of justice, and putting your legs ready preaching the gospel of peace. (shrink)
C.H. Waddington is today remembered chiefly as a Drosophila developmental geneticist who developed the concepts of “canalization” and “the epigenetic landscape.” In his lifetime, however, he was widely perceived primarily as a critic of Neo-Darwinian evolutionary theory. His criticisms of Neo-Darwinian evolutionary theory were focused on what he saw as unrealistic, “atomistic” models of both gene selection and trait evolution. In particular, he felt that the Neo-Darwinians badly neglected the phenomenon of extensive gene interactions and that the “randomness” of (...) mutational effects, posited in the theory, was a false postulate. This last criticism dealt with the phenomenon known today as “developmental constraints.” Although population genetics itself has evolved considerably from its form at mid-20th century, much of Waddington’s critique, it is argued here, retains cogency. Yet, he did not attempt to develop a full-fledged alternative theory himself. Perhaps most surprisingly, in retrospect, is that he did not try to marry his work on gene interactions in development with his evolutionary interests, to create a theory of “genetic networks” and their evolution. Whether evolutionary genetics today will incorporate “network thinking” as a central element or whether there will be a general retreat to the more atomistic approach offered by genomics, remains an open question. (shrink)
_Epistemic Logic_ studies statements containing verbs such as 'know' and 'wish'. It is one of the most exciting areas in medieval philosophy. Neglected almost entirely after the end of the Middle Ages, it has been rediscovered by philosophers of the present century. This is the first comprehensive study of the subject. Ivan Boh explores the rules for entailment between epistemic statements, the search for the conditions of knowing contingent propositions, the problems of substitutivity in intentional contexts, the relationship between (...) epistemic and modal logic, and the problems of composite and divided senses in authors ranging from Abelard to Frachantian. (shrink)
_Epistemic Logic_ studies statements containing verbs such as 'know' and 'wish'. It is one of the most exciting areas in medieval philosophy. Neglected almost entirely after the end of the Middle Ages, it has been rediscovered by philosophers of the present century. This is the first comprehensive study of the subject. Ivan Boh explores the rules for entailment between epistemic statements, the search for the conditions of knowing contingent propositions, the problems of substitutivity in intentional contexts, the relationship between (...) epistemic and modal logic, and the problems of composite and divided senses in authors ranging from Abelard to Frachantian. (shrink)
In 1956, in his Principles of Embryology, Conrad Hal Waddington explained that the word “epigenetics” should be used to translate and update Wilhelm Roux’ German notion of “Entwicklungsmechanik” to qualify the studies focusing on the mechanisms of development. When Waddington mentioned it in 1956, the notion of epigenetics was not yet popular, as it would become from the 1980s. However, Waddington referred first to the notion in the late 1930s. While his late allusion clearly reveals that (...) class='Hi'>Waddington readily associated the notion of epigenetics with the developmental process, in the contemporary uses of the notion this developmental connotation seems to have disappeared. The advent and success of molecular biology have probably contributed to focusing biologists’ attention on the “genetic” or the “non-genetic” over the “developmental”. In the present paper, I first examine the links that exist, in Waddington’s work, between the classical notion of epigenesis in embryology and those of epigenetics that Waddington proposed to connect, and even synthesize, data both from embryology and genetics. Second, I show that Waddington’s own view of epigenetics has changed over time and I analyze how these changes appear through his many representations of the relationships between genetic signals and developmental processes. (shrink)
Conrad Hal Waddington was a British developmental biologist who mainly worked in Cambridge and Edinburgh, but spent the late 1930s with Morgan in California learning about Drosophila. He was the first person to realize that development depended on the then unknown activities of genes, and he needed an appropriate model organism. His major experimental contributions were to show how mutation analysis could be used to investigate developmental mechanisms in Drosophila, and to explore how developmental mutation could drive evolution, his (...) other deep interest. Waddington was, however, predominantly a thinker, and set out to provide a coherent framework for understanding the genetic bases of embryogenesis and evolution, developing his ideas in many books. Perhaps his best-known concept is the epigenetic landscape: here a ball rolls down a complex valley, making path choices. The rolling ball represents a cell’s development over time, while the topography represents the changing regulatory environment that controls these choices. In its later forms, the role of each feature in the landscape was controlled by the effects of sets of interacting genes, an idea underpinning contemporary approaches to systems biology. Waddington was the first developmental geneticist and probably the most important developmental biologist of the pre-molecular age. (shrink)
In this essay, David Waddington provides a basic outline of John Dewey's often‐overlooked views on technology education and explores how these ideas could be updated productively for use in contemporary contexts. Some of the shortcomings of Dewey's ideas are also examined—his faith in the scientific method may have been excessive, and some critics have charged that his aspirations for a technology‐infused citizenship education were overly ambitious. However, Waddington contends in this analysis that by combining Dewey's ideas with the (...) insights of contemporary thinkers such as Bruno Latour, it is possible to update the notion of technological transparency to create a fresh approach to science and technology education. This new approach, which Waddington calls “critical transparency,” aims to help citizens develop a healthy skepticism toward science and technology. (shrink)
The philosopher Jorge J. E. Gracia engages fifteen prominent scholars on race, ethnicity, nationality, and Hispanic/Latino identity in the United States. Their discussion joins two distinct traditions: the philosophy of race begun by African Americans in the nineteenth century, and the search for an understanding of identity initiated by Latin American philosophers in the sixteenth century. Participants include Linda M. Alcoff, K. Anthony Appiah, Richard J. Bernstein, Lawrence Blum, Robert Gooding-Williams, Eduardo Mendieta, and Lucius T. Outlaw Jr., and their dialogue (...) reflects the analytic, Aristotelian, Continental, literary, Marxist, and pragmatic schools of thought. These intellectuals start with the philosophy of Hispanics/Latinos in the United States and then move to the philosophy of African Americans and Anglo Americans in the United States and the philosophy of Latin Americans in Latin America. Gracia and his interlocutors debate the nature of race and ethnicity and their relation to nationality, linguistic rights, matters of identity, and Affirmative Action, binding the concepts of race and ethnicity together in ways that open new paths of inquiry. Gracia's Familial-Historical View of ethnic and Hispanic/Latino identity operates at the center of each of these discussions, providing vivid access to the philosopher's provocative arguments while adding unique depth to issues that each of us struggles to understand. (shrink)
In an interesting work ‘The Ethical Animal’ Professor C. H. Waddington valiantly attempts to bridge the gap between ‘ought’ and ‘is’ without, it seems, succeeding in doing so. Notwithstanding his erudition, honesty of purpose and charm in exposition, the gulf remains unbridged. Indeed there are passages where it is difficult to be certain whether the author considers that he has bridged it or even what standpoint he finally adopts.
From the 1930s through the 1970s, C. H. Waddington attempted to reunite genetics, embryology, and evolution. One of the means to effect this synthesis was his model of the epigenetic landscape. This image originally recast genetic data in terms of embryological diagrams and was used to show the identity of genes and inducers and to suggest the similarities between embryological and genetic approaches to development. Later, the image became more complex and integrated gene activity and mutations. These revised epigenetic (...) landscapes presented an image of how mutations could alter developmental pathways to yield larger phenotypic changes. These diagrams became less important as the operon became used to model differential gene regulation. (shrink)
In this essay, Bruce Maxwell, David Waddington, Kevin McDonough, Andrée-Anne Cormier, and Marina Schwimmer compare two competing approaches to social integration policy, Multiculturalism and Interculturalism, from the perspective of the issue of the state funding and regulation of conservative religious schools. After identifying the key differences between Interculturalism and Multiculturalism, as well as their many similarities, the authors present an explanatory analysis of this intractable policy challenge. Conservative religious schooling, they argue, tests a conceptual tension inherent in Multiculturalism between (...) respect for group diversity and autonomy, on the one hand, and the ideal of intercultural citizenship, on the other. Taking as a case study Québec's education system and, in particular, recent curricular innovations aimed at helping young people acquire the capabilities of intercultural citizenship, the authors illustrate how Interculturalism signals a compelling way forward in the effort to overcome the political dilemma of conservative religious schooling. (shrink)
The "theory of mind" framework has been the fastest growing body of empirical research in contemporary psychology. It has given rise to a range of positions on what it takes to relate to others as intentional beings. This book brings together disparate strands of ToM research, lays out historical roots of the idea, and indicates better alternatives.
What Ivan Illich regarded in his Medical Nemesis as the ‘expropriation of health’ takes place on the surfaces and in the spaces of the screens all around us, including our cell phones but also the patient monitors and (increasingly) the iPads that intervene between nurse and patient. To explore what Illich called the ‘age of the show’, this essay uses film examples, like Creed and the controversial documentary Vaxxed, and the television series Nurse Jackie. Rocky’s cancer in his last (...) film (submitting to chemo to ‘fight’ cancer) highlights what Illich along with Petr Skrabanek called the ‘expropriation of death’. In contrast to what Illich denotes as ‘Umsonstigkeit’ – i.e., a free gift, given undeservedly, i.e., gratuitously – medical science tends to be tempted by what Illich terms scientistic ‘black magic’, taking over (expropriating) the life and the death of the patient in increasingly technological ways, a point underscored in the concluding section on the commercial prospects of xenotransplants using factory farm or mass-produced (and already for some time) human-pig mosaics or chimeras. (shrink)
Gatchel, R. H. The evolution of the concept.--Wilson, J. Indoctrination and rationality.--Green, T. F. Indoctrination and beliefs.--Kilpatrick, W. H. Indoctrination and respect for persons.--Atkinson, R. F. Indoctrination and moral education.--Flew, A. Indoctrination and doctrines.--Moore, W. Indoctrination and democratic method.--Wilson, J. Indoctrination and freedom.--Flew, A. Indoctrination and religion.-- White, J. P. Indoctrination and intentions.--Crittenden, B. S. Indoctrination as mis-education.--Snook, I. A. Indoctrination and moral responsibility.--Gregory, I. M. M. and Woods, R. G. Indoctrination: inculcating doctrines.-- White, J. P. Indoctrination without doctrines?
The enigmatic thought of Charles S. Peirce, considered by many to be one of the great philosophers of all time, involves inquiry not only into virtually all branches and sources of modern semiotics, physics, cognitive sciences, and mathematics, but also logic, which he understood to be the only useful approach to the riddle of reality. This book represents an attempt to outline an analytical method based on Charles Peirce’s least explored branch of philosophy, which is his evolutionary cosmology, and his (...) notion that the universe is made of an ‘effete mind.’ The chief argument conceives of human discourse as a giant metaphor in regard to outside reality. The metaphors arise in our imagination as lightning-fast schemes for acting, speaking, or thinking. To illustrate this, each chapter will present a well-known metaphor and explain how it is unfolded and conceptualized according to the new method for revealing meaning. This original work will interest students and scholars in many fields including semiotics, linguistics and philosophy. (shrink)
Conversation analysts have noted that, in psychotherapy, formulations of the client's talk can be a vehicle for offering a psychological interpretation of the client's circumstances. But we notice that not all formulations in psychotherapy offer interpretations. We offer an analysis of formulations that are diagnostic: that is, used by the professional to sharpen, clarify or refine the client's account and make it better able to provide what the professional needs to know about the client's history and symptoms. In doing so, (...) these formulations also have the effect of shepherding the client's account towards subsequent therapeutic interpretation. In a coda, we notice that sometimes the formulations are designed discreetly. We examine one such discreet formulation in detail, and show how its very ambiguity can lead to its failure as a diagnostic probe. (shrink)
Recent theological anthropology emphasizes a dynamic and integral understanding of the human being, which is also related to Karl Rahner's idea of active self-transcendence and to the imago Dei doctrine. The recent neuroscientific discovery of the “visual word form area” for reading, regarded in light of the concept of cultural neural reuse, will produce fresh implications for the interrelation of brain biology and human culture. The theological and neuroscientific parts are shown in their mutual connections thus articulating the notion that (...) human beings shape and transcend themselves both at the biological and at the cultural level. This will have relevant implications for the timely topic of human uniqueness in science and theology, and in proposing a new research perspective in which theology may consider culture along with its biological import, but not necessarily in strictly evolutionary terms alone. (shrink)
This Special Issue brings a selection of peer-reviewed papers that were presented at the 12th Principia International Symposium: Models and Modeling in the Sciences, Florianópolis, Brazil, online, August 2021. In this preface, the chair and the secretary of the organizing committee comment the symposium's context and briefly present the issue.
Epistemic logic is one of the most exciting areas in medieval philosophy. Neglected almost entirely after the end of the Middle Ages, it has been rediscovered by philosophers of the twentieth century. Epistemic Logic in the Later Middle Ages provides the first comprehensive study of the subject. Ivan Boh explores the contrast between epistemic and alethic conceptions of consequence, the general epistemic rules of consequence, the search for conditions of knowing contingent propositions, the problems of substitutivity in intentional contexts, (...) the considerations of epistemic/doxastic iterated modalities, and the problems of composite and divided senses in authors ranging from Abelard to Frachantian. Boh concludes with a comparison between medieval endeavors and the epistemic logic of our own times. Written in a clear and readable style with minimal symbolic apparatus, this book employs modern symbolism and conceptual frameworks, and complements the studies of the syntacticand semantic dimensions of medieval logic. (shrink)
It seems that the reception of Conrad Hal Waddington’s work never really gathered speed in mainstream biology. This paper, offering a transdisciplinary survey of approaches using his epigenetic landscape images, argues that (i) Waddington’s legacy is much broader than is usually recognized—it is widespread across the life sciences (e.g. stem cell biology, developmental psychology and cultural anthropology). In addition, I will show that (ii) there exist as yet unrecognized heuristic roles, especially in model building and theory formation, which (...)Waddington’s images play within his work. These different methodological facets envisioned by Waddington are used as a natural framework to analyze and classify the manners of usage of epigenetic landscape images in post-Waddingtonian ‘landscape approaches’. This evaluation of Waddington’s pictorial legacy reveals that there are highly diverse lines of traditions in the life sciences, which are deeply rooted in Waddington’s methodological work. (shrink)
Resumo Este artigo apresenta um referencial pragmatista para compreender o estatuto epistêmico da valoração que é produzida na reflexão acerca das consequências sociais de propostas científicas e tecnológicas. O problema é posto, seguindo-se as considerações de Bertrand Russell sobre o impacto da ciência na sociedade. Russell argumenta que a valoração de arranjos sociais fica fora dos limites do conhecimento, porque valorações não podem ser verdadeiras ou falsas, em sentido correspondencial. Isso leva o pensamento social a um impasse, pois não se (...) pode saber que dado arranjo social seria indesejável ou inadequado. Este texto esboça uma alternativa, a partir dos trabalhos sobre valoração de Clarence Irving Lewis, tomados em continuidade com a teoria da investigação de John Dewey. Esse referencial alternativo assume noções epistêmicas de verdade e justificação, o que permite que valorações possam ser concebidas em contextos de investigação e, assim, como objetos de conhecimento.This article presents a pragmatist framework to understand the epistemic status of valuations produced upon reflection on social consequences of scientific and technological proposals. The problem is set following Bertrand Russell’s considerations on the impact of science on society. Russell argues that valuating social arrangements falls beyond the limits of knowledge, because valuations cannot be true or false in the sense of correspondence. This leads social thought to a deadlock, since one cannot know that a given social arrangement would be undesirable or inadequate. This article sketches an alternative from Clarence Irving Lewis’s works on valuation taken in continuity with John Dewey’s theory of inquiry. This alternative framework assumes epistemic notions of truth and justification, allowing that valuations can be construed in contexts of inquiry and thus as objects of knowledge. (shrink)
This book is a colorful journey into the fascinatingly diverse world of interneurons, an important class of highly heterogeneous cells found in all cortical neuronal networks. Interneurons are known to play key roles in many brain functions, from sensory processing to neuronal oscillations linked to learning and memory. The central aim of the volume is to provide new insights into the striking degree of cellular diversity found in interneuronal microcircuits. The book discusses the history of research into interneuronal variability, the (...) developmental origins of interneuronal diversity, the functional roles of heterogeneity in neuronal circuits, contemporary interneuronal classification systems, and the genetic and homeostatic mechanisms that shape the degree of cell to cell variability within interneuronal populations. It elaborates on new ideas about interneuronal diversity that rest upon theoretical and experimental results, with arguments touching upon evolution, animal behavior, and the mathematical theory of small world networks. This engaging volume is invaluable to neuroscientists and others interested in how neuronal newtworks function; electrical engineers, computational modelers, and physicists interested in neuronal network theory; neurologists and psychiatrists working on mechanisms of neurological and psychiatric disorders; and students and trainees in all of these fields. (shrink)
