IntroductionA symptom cluster is very common among oncological patients: cancer-related fatigue, emotional distress, sleep difficulties, pain, and cognitive difficulties. Clinical applications of interventions based on non-ordinary states of consciousness, mostly hypnosis and meditation, are starting to be investigated in oncology settings. They revealed encouraging results in terms of improvements of these symptoms. However, these studies often focused on breast cancer patients, with methodological limitations. Another non-ordinary state of consciousness may also have therapeutic applications in oncology: self-induced cognitive trance. It seems (...) to differ from hypnosis and meditation, as it involves the body more directly. Thus, investigating its clinical applications, along with hypnosis and meditation interventions, could improve available therapeutic options in oncology. This article details the study protocol of a preference-based longitudinal controlled superiority trial aiming to assess the effectiveness of 3 group interventions to improve oncological patients’ quality of life, and more specifically CRF, emotional distress, sleep, pain, and cognitive difficulties.Methods and analysisA power analysis required a total sample of 160 patients. Main inclusion criteria are: cancer diagnosis, active treatments completed for less than a year, no practice of hypnosis, meditation, or SICT, and presence of at least one of these four symptoms: fatigue, sleep difficulties, depression, or anxiety. Each participant will choose the intervention in which they want to participate. To test the effectiveness of the interventions, data will be collected by questionnaires and neurobiological measures and directly from the medical record at four time points: before inclusion in the study ; immediately after the intervention; and at 3- and 12-month follow-up. The longitudinal data in each group will then be measured.DiscussionIn addition to standard cancer therapies, there is a growing interest from patients in complementary approaches, such as hypnosis, meditation, and SICT. The results of this study will be useful to increase knowledge about short- and long-term effectiveness of 3 group interventions for CRF, emotional distress, sleep, pain, and cognitive difficulties in patients with different cancers.Clinical Trial RegistrationClinicalTrials.gov/. Retrospectively registered on the 29th of April 2021. url: https://clinicaltrials.gov/ct2/show/NCT04873661. (shrink)

Despite the importance of the Judgement of Paris in the story of the Trojan War, the Iliad has only one explicit reference to it. This occurs, rather out of the blue, in the final book of the poem in a dispute among the gods about the treatment of Hector's body. Achilles keeps dragging the body around behind his chariot, but Apollo protects it with his golden aegis. Apollo then speaks among the gods and attacks the conduct of Achilles, claiming at (...) the end that he offends the dumb earth. Other gods too have their concerns about what is going on, and they keep trying to get Hermes to snatch the body away. The three most powerful divine enemies of Troy, however, Hera, Poseidon and Athena, will have none of this. They remain as hostile to Troy and Priam and his people as they ever were, and it is in this context that the Judgement of Paris is mentioned: ἔνθ' ἄλλοις μὲν πᾶσιν ἑήνδανɛν, οὐδέ πoθ' Ἥρῃοὐδὲ Ποσɛιδάων' οὐδὲ γλαυκώπιδι κούρῃ,ἀλλ' ἔχον ὥς σϕιν πρῶτον ἀπήχθɛτο Ἴλιος ἱρὴκαὶ Πρίαμος καὶ λαὸς Ἀλɛξάνδρου ἕνɛκ' ἄτης,ὃς νɛίκɛσσɛ θɛάς, ὅτɛ οἱ μέσσαυλον ἵκοντο,τὴν δ' ᾔνησ' ἥ οἱ πόρɛ μαχλοσύνην ἀλɛγɛινήν.And this was pleasing to all the others, but never to Heranor to Poseidon, nor to the flashing-eyed maiden,but they remained hostile to sacred Ilios as in the beginning,and to Priam and to his people, because of Alexander's folly,he who insulted the goddesses when they came to his inner courtyardand praised her who provided his grievous lust. (shrink)