In book X of the Republic, Plato famously reports “a quarrel between poetry and philosophy.” The present essay examines this quarrel in book X, along with other relevant parts of the Republic, by understanding “philosophy” and “poetry” as rival ways of life and rival ways of discourse. The essay first explains why, in Plato’s view, poetic discourse weakens one’s power to reason and is at odds with philosophic discourse. Then it shows how poetic discourse is bound up with a way (...) of life that champions the value of freedom. Such a life forms a contrast with the philosophic life, which is marked more by stability and unity than by freedom. The quarrel, however, is not a simple antagonism. The essay hence concludes by discussing why, despite the opposition between the two, philosophy cannot do without poetry. (shrink)

Hume’s moral philosophy is a sentiment-based view. Moral judgment is a matter of the passions; certain traits of character count as virtues or vices because of the approval or disapproval they evoke in us, feelings that express concern we have about the social effects of these traits. A sentiment-based approach is attractive, since morality seems fundamentally to involve caring for other people. Sentiment-based views, however, face a real challenge. It is clear that our affections are often particular; we favor certain (...) persons over others. This poses a problem when it comes to determining the proper content of morality. The ties of sentiment would seem to be in tension with the aspirations of morality toward impartiality and universality. (shrink)

In a previous issue of Zygon (Carvalho 2007), I explored the role of scientists—especially those engaging the science-religion dialogue—within the arena of global equity health, world poverty, and human rights. I contended that experimental biologists, who might have reduced agency because of their professional workload or lack of individual resources, can still unite into collective forces with other scientists as well as human rights organizations, medical doctors, and political and civic leaders to foster progressive change in our world. In this (...) article, I present some recent findings from research on three emerging viruses—HIV, dengue, and rotavirus—to explore the factors that lead to the geographical expansion of these viruses and the increase in frequency of the infectious diseases they cause. I show how these viruses are generating problems for geopolitical stability, human rights, and equity health care for developing nations that are already experiencing a growing poverty crisis. I suggest some avenues of future research for the scientific community for the movement toward resolution of these problems and indicate where the science-religion field can be of additional aid. (shrink)

Exact definitions in physical and biological terms of the coefficients in Volterra's (1926, 1931) original competition equations are indispensable for the understanding of the system. In agreement with Volterra's own, but not quite sufficient specifications, it is tried in this paper to give more precise definitions of the parameters used by Volterra. This leads to some consequences; i.a. that there does not exist a principle of competitive exclusion. In order to allow for competitive exclusion — or for stabilization — the (...) Volterra equations need additional biophysical specifications and mathematical modifications. Some such modifications are proposed, for instance for aggressive interference as a function of population numbers. (shrink)

Change is endemic in nature yet scientists seek stability amidst change. When proposals fail scientists shift their focus and look for stability elsewhere. Scholars who study the development of science also seek stability in the scientific process. Here I explore the interaction between stability and change in nature as we understand it through the sciences and in the practice of scientific research. The concluding part argues that the search for stability meets a human intellectual need but this is compatible with (...) our finding what is actually there. Cases in which a previously accepted part of science is rejected or revised in response to contrary data indicates that we do not predetermine outcomes of observations and experiments. Still, the belief that there are loci of stability in nature is a working hypothesis. While it has been fruitful, only future scientific developments can determine if this will continue to hold. (shrink)

Group size is a function of relative neocortical volume in nonhuman primates. Extrapolation from this regression equation yields a predicted group size for modern humans very similar to that of certain hunter-gatherer and traditional horticulturalist societies. Groups of similar size are also found in other large-scale forms of contemporary and historical society. Among primates, the cohesion of groups is maintained by social grooming; the time devoted to social grooming is linearly related to group size among the Old World monkeys and (...) apes. To maintain the stability of the large groups characteristic of humans by grooming alone would place intolerable demands on time budgets. It is suggested that (1) the evolution of large groups in the human lineage depended on the development of a more efficient method for time-sharing the processes of social bonding and that (2) language uniquely fulfills this requirement. Data on the size of conversational and other small interacting groups of humans are in line with the predictions for the relative efficiency of conversation compared to grooming as a bonding process. Analysis of a sample of human conversations shows that about 60% of time is spent gossiping about relationships and personal experiences. It is suggested that language evolved to allow individuals to learn about the behavioural characteristics of other group members more rapidly than is possible by direct observation alone. (shrink)

The present article commences analyzing the origins and influences of the religious discourse on the configuration of the modern constitutional discourse and the contributions of the jus-positivism in the consolidation of this sacred-civil language. The second issue is the definition of the U.S. Constitution as a mixed and not as a democratic constitution, with regard to the influences of Plato, Aristotle, Cicero and Polybius to the Drafters of the first modern constitutional text; stability and equilibrium took preference over democracy in (...) a wide sense. I also analyze how the Drafter’s decision has conditioned the modern constitutional system up to the present. (shrink)

Biological individuality is a notoriously thorny topic for biologists and philosophers of biology. In this paper we argue that biological individuality presents multiple, interconnected questions for biologists and philosophers that together form a problem agenda. Using a case study of an interdisciplinary research group in ecology, behavioral and evolutionary biology, we claim that a debate on biological individuality that seeks to account for diverse practices in the biological sciences should be broadened to include and give prominence to questions about uniqueness (...) and temporality. We show that broadening the problem agenda of biological individuality draws attention to underrecognized philosophical issues and discussions and thereby organizes and enriches the existing debate. (shrink)

In book X of the Republic, Plato famously reports “a quarrel between poetry and philosophy.” The present essay examines this quarrel in book X, along with other relevant parts of the Republic, by understanding “philosophy” and “poetry” as rival ways of life and rival ways of discourse. The essay first explains why, in Plato’s view, poetic discourse weakens one’s power to reason and is at odds with philosophic discourse. Then it shows how poetic discourse is bound up with a way (...) of life that champions the value of freedom. Such a life forms a contrast with the philosophic life, which is marked more by stability and unity than by freedom. The quarrel, however, is not a simple antagonism. The essay hence concludes by discussing why, despite the opposition between the two, philosophy cannot do without poetry. (shrink)

In the present paper, we introduce new models of pendulum motions for two cases: the first model consists of a pendulum with mass M moving at the end of a string with a suspended point moving on an ellipse and the second one consists of a pendulum with mass M moving at the end of a spring with a suspended point on an ellipse. In both models, we use the Lagrangian functions for deriving the equations of motions. The derived equations (...) are reduced to a quasilinear system of the second order. We use a new mathematical technique named a large parameter method for solving both models’ systems. The analytical solutions are obtained in terms of the generalized coordinates. We use the numerical techniques represented by the fourth-order Runge–Kutta method to solve the autonomous system for both cases. The stabilities of the obtained solutions are studied using the phase diagram procedure. The obtained numerical solutions and analytical ones are compared to examine the accuracy of the mathematical and numerical techniques. The large parameter technique gives us the advantage to obtain the solutions at infinity in opposite with the famous Poincare’s method which was used by many outstanding scientists in the last two centuries. (shrink)

Individuals of many animal species are said to have a personality. It has been shown that some individuals are bolder than other individuals of the same species, or more sociable or more aggressive. In this paper, we analyse what it means to say that an animal has a personality. We clarify what an animal personality is, that is, its ontology, and how different personality concepts relate to each other, and we examine how personality traits are identified in biological practice. Our (...) analysis shows that biologists often study specific personality traits, such as boldness, sociability or aggressiveness, rather than personalities in general. We claim that personality traits are best understood as dispositions and that they are operationally defined in terms of certain sets of behaviours, which are studied in specific experimental set-ups. Furthermore, we develop an integrative philosophical account that specifies and formalises three criteria for identifying personality traits, which are used in biological practice. For an individual animal to have a personality trait it must, first, behave differently than others. Second, these behavioural differences must be stable over a certain time, and third, they must be consistent in different contexts. (shrink)

The purpose of the article is the analysis of the causes of the systemic crisis that hit modern civilization through the description of its main structures, identifying the relationship between its elements, assessments of their heuristic potential. This will open up opportunities for finding ways to resolve this crisis, new directions of civilizational development. Theoretical basis of the research are the systems analysis, socio-philosophical and philosophical-anthropological approaches as well as the analysis of scientific developments in the field of global studies. (...) Originality lies in the fact that this article is the first to show the connection between the main structural elements of human civilization as a system. Change in one of the parameters leads to a change in all the others, together with a change in civilization as a whole. Conclusions. The reason for the deep crisis that hit modern civilization is its imbalance as a system. The most important elements of this system are population size, resources and technology, and the core is consciousness in its individual and collective forms. The perception, processing, and use of information, which is a defining civilizational resource, as well as the stability of the entire system depend on the state of consciousness. Consciousness, based on old, obsolete principles and stereotypes, is unable to cope with the most acute challenges of time. New consciousness, since it is formed, will mark the transition to a new theoretical picture of the world and a model of human behavior, in which people will act, driven by proven knowledge, and not willfulness and prejudice. The idea of forming a productive information environment where the ideas of constructiveness and creative work will dominate rather than consumerism and destruction, as is the case at present, must become the categorical imperative of the new consciousness. (shrink)

The present article commences analyzing the origins and influences of the religious discourse on the configuration of the modern constitutional discourse and the contributions of the jus-positivism in the consolidation of this sacred-civil language. The second issue is the definition of the U.S. Constitution as a mixed and not as a democratic constitution, with regard to the influences of Plato, Aristotle, Cicero and Polybius to the Drafters of the first modern constitutional text; stability and equilibrium took preference over democracy in (...) a wide sense. I also analyze how the Drafter’s decision has conditioned the modern constitutional system up to the present. (shrink)

This essay explores the universal cognitive bases of biological taxonomy and taxonomic inference using cross-cultural experimental work with urbanized Americans and forest-dwelling Maya Indians. A universal, essentialist appreciation of generic species appears as the causal foundation for the taxonomic arrangement of biodiversity, and for inference about the distribution of causally-related properties that underlie biodiversity. Universal folkbiological taxonomy is domain-specific: its structure does not spontaneously or invariably arise in other cognitive domains, like substances, artifacts or persons. It is plausibly an innately-determined (...) evolutionary adaptation to relevant and recurrent aspects of ancestral hominid environments, such as the need to recognize, locate, react to, and profit from many ambient species. Folkbiological concepts are special players in cultural evolution, whose native stability attaches to more variable and difficult-to-learn representational forms, thus enhancing the latter's prospects for regularity and recurrence in transmission within and across cultures. This includes knowledge that cumulatively enriches (folk expertise), overrides (religious belief) or otherwise transcends (science) the commonsense ontology prescribed by folkbiology. Finally, the studies summarized here indicate that results gathered from “standard populations” in regard to biological categorization and reasoning more often than not fail to generalize in straightforward ways to humanity at large. This suggests the need for much more serious attention to cross-cultural research on basic cognitive processes. (shrink)

The capacity of cells and organisms to respond to external stimuli and to maintain stability in order to survive decreases progressively during ageing. The mitogenic and stimulatory effects of growth factors, hormones and other agents are reduced significantly during cellular ageing. The sensitivity of ageing cells to toxic agents including antibiotics, phorbol esters, radiations and heat shock increases. This failure of homeostasis during cellular ageing does not appear to be due to any quantitative and qualitative defects in the receptor systems. (...) Instead, metabolic defects in the pathways of macromolecular synthesis may be the basis of altered cellular responsiveness during ageing. (shrink)

Current phylogenies show that paired fins and limbs are unique to jawed vertebrates and their immediate ancestry. Such fins evolved first as a single pair extending from an anterior location, and later stabilized as two pairs at pectoral and pelvic levels. Fin number, identity, and position are therefore key issues in vertebrate developmental evolution. Localization of the AP levels at which developmental signals initiate outgrowth from the body wall may be determined by Hox gene expression patterns along the lateral plate (...) mesoderm. This regionalization appears to be regulated independently of that in the paraxial mesoderm and axial skeleton. When combined with current hypotheses of Hox gene phylogenetic and functional diversity, these data suggest a new model of fin/limb developmental evolution. This coordinates body wall regions of outgrowth with primitive boundaries established in the gut, as well as the fundamental nonequivalence of pectoral and pelvic structures. BioEssays 20:371–381, 1998. © 1998 John Wiley & Sons Inc. (shrink)

The dynamics of populations of self-replicating, hierarchically structured individuals, exposedto accidents which destroy their sub-units, is analyzed mathematically, specifically with regardto the roles of redundancy and sexual repair. The following points emerge from this analysis:0 A population of individuals with redundant sub-structure has no intrinsic steady-statepoint; it tends to either zero or infinity depending on a critical accident rate α c . Increased redundancy renders populations less accident prone initially, but populationdecline is steeper if a is greater than a fixed (...) value α d . Periodic, sexual repair at system-specific intervals prevents continuous decline and stabilizesthe population insofar as it will now oscillate between two fixed population levels. The stabilizing sexual interval increases with increased complexity provided this is accom-panied by appropriate levels of redundancy. The model closely simulates the dynamics of heterosis effects. Repair fitness is a population fitness: the chance of an individual being repaired is a functionof the statistical make-up of the population as a whole at that particular period. Populationsliving at α > α c either engage in sexual repair at the appropriate time or they die out. The mathematical properties of the model illustrate mechanisms which possibly played arole in the evolution of a mortal soma in relation to sexual reproduction. (shrink)

Automated neuropsychiatric batteries have been used in research and clinical practice, including for chronic diseases, such as Systemic Lupus Erythematosus. The Pediatric Automated Neuropsychological Assessment Metrics battery, originally developed for use in American-English speaking individuals, allows tracking of cognitive functions. It can be applied to people over 9 years old. The aim of this study was to translate and present initial validation data from the Ped-ANAM into Brazilian-Portuguese. We translated the battery according to Beaton’s guidelines. Psychometric properties were tested, internal (...) consistency was analyzed by Cronbach’s alpha coefficient, test-retest reliability by the intraclass correlation coefficient. Further, we measured the test execution speed at both times as a temporal stability. Principal component analysis was used for structural validity. Evidence of construct validity was assessed through assessment of the relationships with the Wechsler Intelligence Scales. All participants prior to the start of study related activities signed an informed consent form approved by the local ethics committee. A sample of 230 individuals [mean of age: 23 years; 65% females] was included; a subset of 51 individuals [mean of age: 18 years, 59% female] completed the Ped-ANAM twice to assess test-retest reliability, and another subset of 54 individuals [mean of age: 20.4 years; 67% female] completed the Wechsler Intelligence Scales for Children and Adult for assessment of the Ped-ANAM’s construct validity. Our results suggest that the internal consistency of the Ped-ANAM and its subtest test-retest reliability were excellent. There was no clustering in the Principal Components Analysis, suggestive of non-grouping of the evaluated variables. Construct validity assessment to the Wechsler Scales showed expected ranges of low to strong correlations. We concluded that, based on the results of this study, a cross-culturally validated Brazilian-Portuguese version of the Ped-ANAM has been developed and it is a reliable tool for the screening cognitive function. (shrink)

The present article commences analyzing the origins and influences of the religious discourse on the configuration of the modern constitutional discourse and the contributions of the jus-positivism in the consolidation of this sacred-civil language. The second issue is the definition of the U.S. Constitution as a mixed and not as a democratic constitution, with regard to the influences of Plato, Aristotle, Cicero and Polybius to the Drafters of the first modern constitutional text; stability and equilibrium took preference over democracy in (...) a wide sense. I also analyze how the Drafter’s decision has conditioned the modern constitutional system up to the present. (shrink)

John Maynard Smith was the founder of evolutionary game theory. He has also been the major influence on the direction of this field, which now pervades behavioural ecology and evolutionary biology. In its original formulation the theory had three components: a set of strategies, a payoff structure, and a concept of evolutionary stability. These three key components are still the basis of the theory, but what is assumed about each component is often different to the original assumptions. We review modern (...) approaches to these components. We emphasis that if a game is considered in isolation, and arbitrary payoffs are assumed, then the payoffs may not be consistent with other components of the system which are not modelled. Modelling the whole system, including not only the focal game, but also the future behaviour of the players and the behaviour of other population members, allows a consistent model to be constructed. We illustrate this in the case of two models of parental care, showing how linking a focal game to other aspects of the system alters what is predicted. (shrink)

Natural selection of specific protobiomonomers during abiogenic development of the prototype genetic code is hindered by the diversity of structural, spatial, and rotational isomers that have identical elemental composition and molecular mass (M), but can vary significantly in their physicochemical characteristics, such as the melting temperature Tm, the Tm:M ratio, and the solubility in water, due to different positions of atoms in the molecule. These parameters differ between cis- and trans-isomers of dicarboxylic acids, spatial monosaccharide isomers, and structural isomers of (...) α-, β-, and γ-amino acids. The stable planar heterocyclic molecules of the major nucleobases comprise four (C, H, N, O) or three (C, H, N) elements and contain a single –C=C bond and two nitrogen atoms in each heterocycle involved in C–N and C=N bonds. They exist as isomeric resonance hybrids of single and double bonds and as a mixture of tautomer forms due to the presence of –C=O and/or –NH2 side groups. They are thermostable, insoluble in water, and exhibit solid-state stability, which is of central importance for DNA molecules as carriers of genetic information. In M–Tm diagrams, proteinogenic amino acids and the corresponding codons are distributed fairly regularly relative to the distinct clusters of purine and pyrimidine bases, reflecting the correspondence between codons and amino acids that was established in different periods of genetic code development. The body of data on the evolution of the genetic code system indicates that the elemental composition and molecular structure of protobiomonomers, and their M, Tm, photostability, and aqueous solubility determined their selection in the emergence of the standard genetic code. (shrink)

Environmentalists commonly offer three motives for why human populations need to be reduced or stabilized. One group maintains that human numbers threaten natural goods that should be preserved: biodiversity and ecosystems. A more extreme group maintains that we are taking up more than our fair share of the planet, eliminating species that have just as much right to be here. A third group advocates controlling human populations in order to prevent the environment from being degraded to the point that it (...) harms people. I intend to examine in light of Catholic social teaching whether these proposed motives for controlling population are always anti-life. (shrink)

The current moment must be seen from a stadial perspective on capitalist development. A new transnational stage is marked by the rise of transnational capital, a transnational capitalist class and state, and novel relations of power and inequality in global society. Recent events do not represent a new U. S. bid for hegemony amidst heightened inter-imperialist rivalry. Faced with increasingly dim prospects for a viable transnational hegemony, transnational elites have mustered up fragmented and incoherent responses involving heightened military coercion, the (...) search for a post-Washington Consensus, and acrimonious internal disputes. This militarized globalization is less a campaign for U. S. hegemony than a contradictory political response to the explosive crisis of global capitalism. Yet the power of collective agencies to influence history is enhanced at such times of crisis, rather than of stability and equilibrium. (shrink)

The article presents a systematic and detailed account of scholarly developments on the problem of studying the process of nation-building and the role of history, memory, language and culture in reflecting this process. The research reveals that according to the premordialist approach, nations are not formed instantaneously, by the relevant political will or by coincidence of circumstances; the process of creating and consolidating a nation is a long and meaningful one, full of historical events and national cultural tokens. The primordialist (...) concepts are considered unanimous in their recognition of the exceptional significance of psychological factors in the creation of a nation. The creation of a nation involves a sophisticated set of linguistic, religious, ethnic, territorial and myth-household factors that determine the formation of a corresponding type of sociality. The framework of the analytics of the phenomenon of a nation includes not only psychological, but also social, cultural, political, ethical, moral and axiological aspects. The new system-building concepts such as solidarity, habitus, plebiscite were added to the discussion of nation. In view of that, it is impossible to carry out the reduction of the phenomenon of a nation to a particular problem field and to localize it to invariant indicators. The formation and optimization of the capitalistic type of social system generates new factors in the interpretation and consolidation of a nation. The reasons for a political defeat in the development of a nation can be referedr to either conscious manipulative techniques, or spontaneous miscalculations. Elaborating the alternative versions of history is nothing but unjustified politicization, implementation of imperial and colonial ambitions, overcoming which is a necessary prerequisite for successful nation-building. The establishment and offsetting of such manipulative influence facilitate the stabilization of the social situation and the resolution of conflicts, and, consequently, contribute to national development. The key point is to establish a nation within the framework of the international and state policy, especially by distinguishing the consolidating and disintegrating influences of state and international politicies on nation-building. The policy of uniting the nation can become effective when the important reforms do not deepen the fragmentation of the nation, but rather neutralize it. (shrink)

A mathematical model for Vibrio Cholerae (V. Cholerae) in a closed environment is considered, with the aim of investigating the impact of climatic factors which exerts a direct influence on the bacterial metabolism and on the bacterial reservoir capacity. We first propose a V. Cholerae mathematical model in a closed environment. A sensitivity analysis using the eFast method was performed to show the most important parameters of the model. After, we extend this V. cholerae model by taking account climatic factors (...) that influence the bacterial reservoir capacity. We present the theoretical analysis of the model. More precisely, we compute equilibria and study their stabilities. The stability of equilibria was investigated using the theory of periodic cooperative systems with a concave nonlinearity. Theoretical results are supported by numerical simulations which further suggest the necessity to implement sanitation campaigns of aquatic environments by using suitable products against the bacteria during the periods of growth of aquatic reservoirs. (shrink)

Modern trends in social development are defined not only as an information society, but increasingly as a knowledge society. To understand its content and strategy of implementation, an important aspect is to understand the contradictions that are increasingly manifested and are of a general socioanthropological nature. In particular, this is the problem of the correlation between a knowledge society and objective scientific knowledge; this is the question of the correlation between the available knowledge and experience reflected in the cultural tradition (...) and the rapidly changing information flow; this is the question of the social role of education and the social status of an educated person, as well as the problem of human self-determination in the context of situational relations and a configurative society, etc.The widespread mythologeme of a knowledge society as a society of intellectuals supports a rather one-sided view of it. Therefore, understanding the paradoxical combination of elements of a knowledge society system, their contradictions, and complementarities, makes it possible to understand the risks and develop tools to avoid them. The research methodology. The study is based on an interdisciplinary and comprehensive analysis of contemporary socio-cultural processes in the context of the formation of a knowledge society and information pedagogy. Research results: The interpretation of modern society as a knowledge society raises a number of theoretical questions and discussions concerning the definition of knowledge (scientific/non-scientific, useful/unsuitable, etc.), and the definition of its social and anthropological characteristics and human status (educated person, informed person, professional person, successful person). The challenges of the processes of informatization of society lead to the formation of «e-didactics» and «information pedagogy» of a new educational paradigm, the effectiveness of which should resolve a number of contradictions. These include, in particular, the discrepancy between learning tools (openness and mobility) and reproductive learning models; between distance asynchronous learning and the classical stability of the structure and forms of organization of the educational process, etc. Discussions. The analysis of knowledge as the fundamental basis of the new social reality and changes in its historical status allows us to identify problematic issues of the worldview picture of the world that is formed in the conditions of intensive production of information and a certain devaluation of knowledge, actualization of innovations, and devaluation of cultural tradition. The knowledge society is often characterized as an education society. Although such a generalization is debatable, educational technologies of knowledge production and transmission are an important component of the development of a knowledge society and include the destruction of stereotypes and attitudes of the industrial society’s education paradigm. This explains why interdisciplinary discussions about the content and forms of organization of modern education are becoming increasingly acute. The problem of rethinking the established models of teacherstudent relations and the requirements for the subjects of the educational process is important among the many aspects of changes. A student is transformed from an object of pedagogical influence into a subject of the educational process, where a teacher plays the role of a mentor, a tutor, since knowledge must be «extracted» by a student because of his or her own intellectual efforts and cognitive search.The change in social role also includes a change in worldview, way of thinking, and value priorities. Conclusion. The analysis of the socio-cultural mechanisms and practices of the knowledge society reveals its ambivalence and risks, which are its inherent characteristics. Knowledge as the fundamental basis of the new social reality is defined not only as a tool for understanding the world but also as a factor of civilizational development that produces new forms of activity and relationships, new worldview orientations, and value priorities. The transformation of the phenomenon of knowledge and the rapidity of the information flow raises the question of the relevance of existing knowledge and experience to the needs of a given situation, thus actualizing the demand not for the depth of knowledge and understanding, but for the ability to combine and choose a practical (useful) option, to put together puzzles and mosaics, forming a clip thinking. Challenges of the processes of society informatization lead to the formation of “e-didactics”, information pedagogy as a tool for adaptation and a new educational paradigm, the effectiveness of which should resolve the identified contradictions.However, the transformation of modern educational practices involves not only rethinking their content, technologies, and teaching methods, changing the status relations of the subjects of the educational process, but also a general change in models of thinking and personal behavior, and a change in the human world. The correlation of the modes of human definition: educated, intellectual, erudite, and specialist becomes an important issue of the anthropological dimension of the knowledge society, where the problem of human self-determination is becoming more acute. (shrink)

Proper interpretation of the problem of contradiction in motion has acquired pressing importance in recent years in conjunction with the development of dialectical materialist concepts of motion, space and time, continuity and discontinuity, infinity, and the like, and also in relations to problems of dialectical logic. In a number of writings , we have attempted to demonstrate that internal contradiction is inherent in motion that inseparably connected with it are such contradictory factors as variability and stability, movement and rest, with (...) variability playing the leading role. Moreover, generally speaking, the concept of preservation, stability or rest means the preservation or maintenance of the very state of motion. (shrink)

Trehalose is a natural disaccharide with a remarkable ability to stabilize biomolecules. In recent years, trehalose has received growing attention as a neuroprotective molecule and has been tested in experimental models for different neurodegenerative diseases. Although the underlying neuroprotective mechanism of trehalose's action is unclear, one of the most important hypotheses is autophagy induction. The chaperone‐like activity of trehalose and the ability to modulate inflammatory responses has also been reported. There is compelling evidence that the dysfunction of autophagy and aggregation (...) of misfolded proteins contribute to the pathogenesis of Alzheimer's disease (AD) and other neurodegenerative disorders. Therefore, given the linking between trehalose and autophagy induction, it appears to be a promising therapy for AD. Herein, the published studies concerning the use of trehalose as a potential therapy for AD are summarized, providing a rationale for applying trehalose to reduce Alzheimer's pathology. (shrink)

The paper reviews the current situation regarding a new theory of brain dynamics put forward by the authors in an earlier publication. Motivation for the theory is discussed in terms of two issues: the long-standing problem of accounting for the stability and nonlocal properties of memory, and the experimental and theoretical evidence against the classical theory of brain action. It is shown that the new theory provides an explanation and a conceptually unifying framework for phenomena of brain action that resist (...) classical explanation. Further independent experiments provide strong additional support for the theory. The fact that this theory incorporates quantum mechanisms in an essential way is considered to be of wide scientific interest in view of the unique status of the brain in relation to the physical, biological, and mental orders in nature. (shrink)

In this article, we present a one-step hybrid block method for approximating the solutions of second-order fuzzy initial value problems. We prove the stability and convergence results of the method and present several examples to illustrate the efficiency and accuracy of the proposed method. The numerical results are compared with the existing ones in the literature.

In this study an analysis is presented of the bonding and structural properties of dehydrogenated and hydrogenated doped cylindrical diamond nanowires calculated using the Vienna Ab Initio Simulation Package, employing density functional theory within the generalized-gradient approximation. The dopants studied here have been inserted substitutionally along the axis of an infinite one-dimensional diamond nanowire and include the single-electron acceptor boron and the single-electron donor nitrogen. The doped nanowires have then been re-relaxed, and properties compared with the undoped structures. The structural (...) properties of relaxed nanowires considered here include an examination bonding via the electron charge density, with the aim of providing a better understanding of the effects of dopants on the stability of diamond nanostructures and nanodevices. (shrink)

In this study an analysis is presented of the bonding and structural properties of dehydrogenated and hydrogenated doped cylindrical diamond nanowires calculated using the Vienna Ab Initio Simulation Package, employing density functional theory within the generalized-gradient approximation. The dopants studied here have been inserted substitutionally, equidistant along the axis of an infinite diamond nanowire. These dopants include aluminium, phosphorus, oxygen and sulphur. The doped nanowires have then been re-relaxed, and properties compared with previously calculated results for undoped, boron-doped and nitrogen-doped (...) structures. Structural properties of relaxed nanowires considered here include an examination bonding via the electron charge density, with the aim of providing a better understanding of the effects of dopants on the stability of diamond nanostructures and nanodevices. (shrink)

A feature of the agro-industrial sphere is the high probability of distribution of production or research sites in areas far from each other for a considerable distance. Moreover, the center for collecting information and processing it, as a rule, is concentrated in one compact place. For research institutions, this feature often acquires a state of rather urgent problem, which requires the search for new innovative approaches. The paper proposes elements of the concept of construction and technological solutions for methods of (...) operational data transfer of field research from agricultural areas to a remote database for data storage with the possibility of feedback. As an example, the procedure of qualification examination of plant varieties with the definition of the criteria of "difference, homogeneity and stability" and "suitability for propagation of the variety in Ukraine" was chosen. (shrink)

A feature of the agro-industrial sphere is the high probability of distribution of production or research sites in areas far from each other for a considerable distance. Moreover, the center for collecting information and processing it, as a rule, is concentrated in one compact place. For research institutions, this feature often acquires a state of rather urgent problem, which requires the search for new innovative approaches. The paper proposes elements of the concept of construction and technological solutions for methods of (...) operational data transfer of field research from agricultural areas to a remote database for data storage with the possibility of feedback. As an example, the procedure of qualification examination of plant varieties with the definition of the criteria of "difference, homogeneity and stability" and "suitability for propagation of the variety in Ukraine" was chosen. (shrink)

Urban agriculture in Cuba has rapidly become a significant source of fresh produce for the urban and suburban populations. A large number of urban gardens in Havana and other major cities have emerged as a grassroots movement in response to the crisis brought about by the loss of trade, with the collapse of the socialist bloc in 1989. These gardens are helping to stabilize the supply of fresh produce to Cuba's urban centers. During 1996, Havana's urban farms provided the city's (...) urban population with 8,500 tons of agricultural produce, 4 million dozens of flowers, 7.5 million eggs, and 3,650 tons of meat. This system of urban agriculture, composed of about 8,000 gardens nationwide has been developed and managed along agroecological principles, which eliminate the use of synthetic chemical pesticides and fertilizers, emphasizing diversification, recycling, and the use of local resources. This article explores the systems utilized by Cuba's urban farmers, and the impact that this movement has had on Cuban food security. (shrink)

In everyday life we either express our beliefs in all-or-nothing terms or we resort to numerical probabilities: I believe it's going to rain or my chance of winning is one in a million. The Stability of Belief develops a theory of rational belief that allows us to reason with all-or-nothing belief and numerical belief simultaneously.