We are of the opinion that there is also identity between erroneous thinking and existence. Our opinion is based on the following facts.

ObjectiveTo elucidate the clinical, radiologic characteristics of Leber’s hereditary optic neuropathy (LHON) associated with the other diseases.Materials and methodsClinical data were retrospectively collected from hospitalized patients with LHON associated with the other diseases at the Neuro-Ophthalmology Department at the Chinese People’s Liberation Army General Hospital (PLAGH) from December 2014 to October 2018.ResultsA total of 13 patients, 24 eyes (10 men and 3 women; mean age, 30.69 ± 12.76 years) with LHON mitochondrial DNA (mtDNA) mutations, were included in the cohort. 14502(5)11778(4)11778 (...) &11696(1)12811(1)11696(1)3460(1). One patient was positive for aquaporin-4 antibody (AQP4-Ab), and two were positive for myelin oligodendrocyte glycoprotein antibody (MOG-Ab). Three patients were associated with idiopathic optic neuritis (ON). Two patients were with compression optic neuropathy. Three patients were with the central nervous system (CNS) diseases. One patient was with proliferative diabetic retinopathy (PDR) and one with idiopathic orbital inflammatory syndrome (IOIS). At the onset, visual acuity (VA) in eighteen eyes was below 0.1, one eye was 0.5, five eyes were above 0.5, while VA in sixteen eyes was below a 0.1 outcome, three eyes experienced moderate vision loss. MRI images showed T2 lesions and enhancement in nine patients who received corticosteroids treatment; additional immune modulators treatment was performed on two patients. None of the patients had relapse during the follow-up time.ConclusionLeber’s hereditary optic neuropathy can be accompanied with multiple-related diseases, especially different subtypes of ON, which were also exhibited with IOIS and compression optic neuropathy for the first time in this cohort. This condition may be a distinct entity with an unusual clinical and therapeutic profile. (shrink)

IntroductionDuring the COVID-19 outbreak, many citizens were asked to stay at home in self-quarantine, which can pose a significant challenge with respect to remaining physically active and maintaining mental health. This study aimed to evaluate the prevalence of inadequate physical activity, anxiety, and depression and to explore the relationship of physical activity with anxiety and depression symptoms among Chinese college students during quarantine.MethodUsing a web-based cross-sectional survey, we collected data from 1,396 Chinese college students. Anxiety and depression were assessed with (...) the Self-Rating Anxiety Scale and the Self-Rating Depression Scale, respectively. The data on physical activity were collected by types of physical activity and the International Physical Activity Questionnaire.ResultsDuring the COVID-19 outbreak, about 52.3% of Chinese college students had inadequate physical activity. The rates of anxiety and depression symptoms were 31.0 and 41.8%, respectively. A high level of physical activity was significantly closely associated with low anxiety, while a moderate, or high level of physical activity was significantly closely associated with reduced depression after adjusting confounding demographic factors. Moreover, specific types of physical activity, such as stretching and resistance training, were negatively correlated with both anxiety and depression; doing household chores was negatively correlated with depression.ConclusionOur findings highlight specific levels and types of home-based physical activities that need to be taken into consideration to protect the mental health of college students during the COVID-19 epidemic. (shrink)

劉智與賈米這兩位時隔幾百年、跨越幾千公里的波斯與中國學者沿著古老的絲綢之路，通過兩者的著述和譯文建立了學術與思想上的聯繫。本書以絲綢之路上的人文交流為時代背景，以波斯蘇非典籍從中亞到中國內地的傳播途徑 與方式為切入點，研究明清時期中國穆斯林知識份子群體出現與發展的歷史背景，以及漢文譯著活動的文化動因，並以此為基礎揭示出劉智與賈米哲學思想的淵源。.

Cognitive and neural processes underlying visual creativity have attracted substantial attention. The current research uses a critical time point analysis to examine how spontaneous activity in the primary visual area is related to visual creativity. We acquired the functional magnetic resonance imaging data of 16 participants at the resting state and during performing a visual creative synthesis task. According to the CTPA, we then classified spontaneous activity in the PVA into critical time points, which reflect the most useful and important (...) functional meaning of the entire resting-state condition, and the remaining time points. We constructed functional brain networks based on the brain activity at two different time points and then subsequently based on the brain activity at the task state in a separate manner. We explore the relationship between resting-state and task-fMRI functional brain networks. Our results found that: the pattern of spontaneous activity in the PVA may associate with mental imagery, which plays an important role in visual creativity; in comparison with the RTPs-based brain network, the CTP-network showed an increase in global efficiency and a decrease in local efficiency; the regional integrated properties of the CTP-network could predict the integrated properties of the creative-network while the RTP-network could not. Thus, our findings indicated that spontaneous activity in the PVA at CTPs was associated with a visual creative task-evoked brain response. Our findings may provide an insight into how the visual cortex is related to visual creativity. (shrink)

Ben shu yi Ming ru Li Cai de jiang xue huo dong yu xue pai jian gou wei zhong xin, tan tao cong shi liu shi ji chu dao shi qi shi ji mo li xue qun ti zhong xin xing xue shuo he xue pai de chan sheng, chuan bo, kuo zhan yu chuan cheng de mo shi, bing zhuo zhong cong si xiang shi de jiao du jie shi zhe zhong mo shi chan sheng he yun xing (...) de si xiang gen yuan yu nei zai dong li. Quan shu zheng wen gong qi zhang, zhu yao nei rong fen wei shang xia liang bian, shang bian yi hong guan zong lun de fang shi, cong li xue jing dian "Da xue" de wen ben bian dong he quan shi jing zheng qie ru, tan tao zhong wan Ming li xue xue shuo he xue pai jian gou de li lun gen ju; xia bian yi Li Cai de "zhi xiu" xue shuo ji qi jiang xue huo dong zuo wei ge an yan jiu, tan tao li xue xue shuo he xue pai de chuan bo ji chuan cheng de she hui hua tu jing. (shrink)

Ben shu yi dao de chuan cheng wei shi jiao,cong yan hui zhi le yu xian, zi gong zhi zhi yu yan, zi lu zhi zhi yu zheng, zi xia zhi xue yu ren si ge fang mian, lun shu zhu xi dui kong zi men ren yan xing de quan shi,cong er jie shi zhu xi dui "Lun yu" zhe yi jing dian suo fan ying de sheng huo shi jie de li jie ji qi he si kao fang (...) shi......shi dui chuan tong zhu xi yan jiu nai zhi song ming li xue yan jiu de yi ge zhong yao bu chong. (shrink)

Some of the authors of the essays on Chinese philosophers prefer the pin yin system of romanization for Chinese names and words, while others prefer the Wade‐Giles system. Given that both systems are in wide use today, important names and words are given in both their pin yin and Wade‐Giles formulations. The author's preference is printed first, followed by the alternative romanization within brackets.

书名原文:Transport processes in plasmas.vol.1,Classisal transport.

No apology, I imagine, is necessary for the appearance of this translation\nof Marx's "Misere de la Philosophic" On the contrary it is strange\nthat it should not have been published in England before, anu that\nthe translation of his monumental work, the "Capital," tardy as that\nwas, should have yet been made before that of a work which was originally\npublished some twenty years before "Capital" first appeared.\n\n\nIt may be that the translators and editors of the latter work were\nof opinion that in view of (...) the comprehensiveness of "Capital," a\npublication of an English edition of the "Misere de la Philosophic"\nwould be a work of supererogation. Or it may be that they thought\na book so distinctly French—as the "Capital" may be said to be distinctly\nEnglish—and which was, further, exclusively a criticism of a work\nof Proudhon's little known in England—would have slight interest\nfor English readers. On the other hand, the groundwork of the theories\nso fully elaborated in "Capital," apart from its exhaustive analysis\nof the capitalist system of production and distribution, will be\nfound in "Misere." In addition, there are several subjects—notably\nthat of rent—dealt with in this volume which are barely touched upon\nin the single book of " Capital " which has been translated into\nEnglish.\n\n\nMarx's criticism of Proudhon's theory that " the time which is necessary\nto create a commodity indicates exactly its degree of utility," so\nthat " the things of which the production costs the least time are\nthe things which are the most immediately useful," has been matched\nby H. M. Hyndman's crushing refutation of the theory of Final Utility.\nThe subject of rent, too, has been fully dealt with by the latter\nin the same book, " The Economics of Socialism," published, as the\nauthor says, in the hope of furnishing " the rapidly-increasing number\nof students of sociology with a concise and readable statement of\nthe main theories of the scientific school of political economy founded\nby Karl Marx and Friedrich Engels." Neither of these facts, however,\nnecessarily detracts from the value of this older work of Marx's.\nOn the question of rent, after reviewing the Ricardian theory and\nthe many objections which present themselves to that theory, Hyndman\nsays: " It seems, therefore, that a wider definition of the rent\nof land under capitalism is needed than that given by Ricardo, and\nthe following is suggested: — Rent of land is that portion of the\ntotal net revenue which is paid to the landlord for the use of plots\nof land after the average profit on the capital embarked in developing\nsuch land has been deducted." On the question of confiscating rent\nhe says it " would not affect the position of the working portion\nof the community unless the money so obtained were devoted to giving\nthem more amusement, to providing them with better surroundings and\nthe like. ... In fact, the attack upon competitive rents is merely\na capitalist attack. That class sees a considerable income going\noff to a set of people who take no part in the direct exploitation\nof labor; and its representatives are naturally anxious to stop this\nleakage, as they consider it, and to reduce their own taxation for\npublic purposes by appropriating rent to the service of the State.\nThat is all very well for them."\n\n\nOn this point Marx says: " We can understand such economists as Mill,\nCherbulliez, Hilditch and others, demanding that rent should be handed\nover to the State to be used for the remission of taxation. That\nis only the frank expression of the hate which the industrial capitalist\nfeels for the landed proprietor, who appears to him as a useless\nincumbrance, a superfluity in the otherwise harmonious whole of bourgeois\nproduction."\n\n\n" Rent," says Marx, " results from the social relations in which exploitation\nis carried on. It cannot result from the nature, more or less fixed,\nmore or less durable, of land. Rent proceeds from society and not\nfrom the soil."\n\n\nThe criticism of Proudhon's appreciation of gold and silver as the\nfirst manifestation of this theory of " constituted value" should\nbe interesting reading to those admirers of the French Anarchist\nwho yet profess their profound detestation of money and its function.\nSo, too, should his declaration against strikes and combinations\nof workmen. In this we see once more how extremes meet. This declaration\nof Proudhon's would not be out of place in the organ of the Liberty\nand Property Defence League.\n\n\nIn this matter of trade union combination, Marx was scarcely accurate\nin his perception of its development. He clearly did not foresee\nthat the great English trade unions would become fossilised, as it\nwere; and that instead of being a revolutionary force they would\nbecome a reactionary mass, opposing the progress of the mere proletarian\noutside their ranks, as they have done. With the spread of Socialist\nideas among them, however, their exclusive character is being modified,\nand they may even yet take that place in the revolutionary working-class\nmovement which Marx anticipated they would occupy. Given this change\nof attitude, the development must inevitably be along the lines he\npredicted. We are seeing "in face of constantly united capital, the\nmaintenance of the association [becoming] more important and necessary\nfor them than the maintenance of wages," and, further, that the combinations\nof capital are forcing the trade unions to that point where "association\ntakes a political character."\n\n\nIt is scarcely necessary to point out that in this work, written in\n1847, some words have a meaning quite other than that which they\nbear to-day. Thus, for instance, the words "Socialists" and "Socialism,"\nwhere they occur, refer to the utopians—who formulated theories of\na social system independent of the industrial evolution— and to these\ntheories themselves.\n\n\nIn most cases the numerous quotations have been verified and reproduced\nin the original. In some instances, however, they are summaries rather\nthan quotations, and appear ^is translated.\n\n\nA translation jn* necessarily an imperfect presentation of the thoughts,\nideas, and conclusions of the author. In this work I have endeavored\nto adhere as closely as possible to the form and letter, as well\nas the spirit of the original, and to this the indulgent reader is\nasked to ascribe such faults of language as would otherwise merit\nhis censure. (shrink)

As more and more multi-national companies expand their operations globally, their responsibilities extend beyond not only the economic motive of profitability but also other social and environmental factors. The objective of this article is to examine the impact of national culture and geographic environment on firms’ corporate social performance (CSP). Empirical tests are based on a global CSP database of companies from 49 countries. Results show that the Hofstede’s cultural dimensions are significantly associated with CSP. In addition, European companies are (...) found to out-perform other regions and countries in CSP. (shrink)

The linguistic theory of Chomsky has changed the long, traditional way of studying language. The nature of knowledge, which is closely tied to human knowledge in general, makes it a logical step for Chomsky to generalize his theory to the study of the relation between language and the world-in particular, the study of truth and reference. But his theory has been controversial and his proposal of "innate ideas" has been resisted by some empiricists who characterize him as rationalist. In our (...) view, these empiricists make a mistake. In the present paper we attend to his position regarding linguistics as a science of mind/brain, which we believe is an important aspect of his theory that has not been paid enough attention or understood by his opponents. In turn, this will help to clarify some of the confusions around his theory. Finally we will discuss some of the debatable issues based on the outlines we draw. (shrink)

Background: The pregnancy and psychological status of infertile couples has always been a concern, but there is no clear evidence for the efficacy of psychotherapy for infertile couples. This study aimed to summarize the current evidence of the effects of psychotherapy on psychological and pregnancy outcomes for infertile couples. Method: We searched Ovid MEDLINE, Ovid EMbase, The Cochrane Library, and Web of Science for articles published from 1946 to June 26, 2020. The pregnancy outcomes, psychological outcomes, and acceptability were involved (...) in the study. Results: Overall, 29 studies with a combined total of 3,522 adult participants were included in the meta-analysis. Compared with a placebo, psychotherapy was associated with the pregnancy rate [risk ratio = 1.43, 95% CI [1.07, 1.93]], total psychological scales associated with infertility [standardized mean difference = −0.33 95% CI [−0.63, −0.02]], subsymptoms of psychological scores using the 28-item version of GHQ, and the integrative body–mind–spirit ; total psychological scales associated with infertility using other treatments and more than a month; and anxiety using BMS had significant statistical significance. The funnel plots of all outcomes were approximately symmetrical, and no significant publication bias was found. Conclusions: The study showed that psychotherapy can lead to improvements in the pregnancy rate for infertile patients, especially for patients receiving assisted fertility. In addition, it may help improve total psychological scales associated with infertility and depression. CBT and BMS play an important role in improving rate of pregnancy, and BMS is associated with reducing anxiety. Although psychological interventions had limited effects on the pregnancy outcomes of infertility, our study still recommended that psychotherapies, in particular CBT and BMS, were applied to the therapeutic regimen for infertility, especially for patients receiving assisted fertility. (shrink)

Evidence suggests divergent thinking is the cognitive basis of creative thoughts. Neuroimaging literature using resting-state functional connectivity has revealed network reorganizations during divergent thinking. Recent studies have revealed the changes of network organizations when performing creativity tasks, but such brain reconfigurations may be prolonged after task and be modulated by the trait of creativity. To investigate the dynamic reconfiguration, 40 young participants were recruited to perform consecutive Alternative Uses Tasks for divergent thinking and two resting-state scans were used for mapping (...) the brain reorganizations after AUT. We split participants into high- and low-creative groups based on creative achievement questionnaire and targeted on reconfigurations of the two brain networks: default-mode network and the network seeded at the left inferior frontal gyrus because the between-group difference of AUT-induced brain activation located at the left IFG. The changes of post-AUT RSFCs indicated the prolonged effect of divergent thinking. More specifically, the alterations of RSFCIFG−AG and RSFCIFG−IPL in the high-creative group had positive relationship with their AUT performances, but not found in the low-creative group. Furthermore, the RSFC changes of DMN did not present significant relationships with AUT performances. The findings not only confirmed the possibility of brain dynamic reconfiguration following divergent thinking, but also suggested the distinct IFGN reconfiguration between individuals with different creativity levels. (shrink)

Background:When the contagious COVID-19 spread worldwide, the frontline staff faced unprecedented excessive work pressure and expectations of all of the society.Objective:The aim was to explore healthcare workers’ stress and influencing factors when caring for COVID-19 patients from an altruistic perspective.Methods:A cross-sectional, descriptive study was conducted in a tertiary hospital during the outbreak of COVID-19 between February and March 2020 in Wuhan, the capital city of Hubei province in China. Data were collected from 1208 healthcare workers. Descriptive statistics and multiple linear (...) regression were used to analyze the data.Ethical considerations:Research ethics approval (with the code of TJ-IRB20200379) was obtained from Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology. Written informed consent was also received from participants.Results:Less than 60% of participants chose moderate or severe stress on all stressors, indicating a low stress level among healthcare workers. The main source of stress among frontline healthcare workers caring for COVID-19 patients came from the fear of being infected, the fear of family members being infected, and the discomfort caused by protective equipment. Frontline staff who were nurses, were married, and had worked more than 20 days suffered higher stress, whereas rescue staff showed lower stress.Conclusion:The healthcare workers caring for patients with COVID-19 had low stress level, although they still had the fear of being infected or uncomfortable feeling caused by personal protective equipment. A low stress level among healthcare workers indicated their professional devotion and altruism during COVID-19 epidemic. Medical institutions and the government should continue to strengthen infection prevention measures and provide more comprehensive care involving families of frontline healthcare workers, especially nurses and married staff. It will be a lesson to other countries that awaking healthcare workers’ inside motivation and providing necessary support from government and society were significant. (shrink)

女真族建立的金朝（1115—1234年）是中国古代历史上一个重要朝代。金建国伊始，即以儒学为国家意识形态，以儒术治国在金代贯彻始终。本书立足文本，从哲学的角度，对金代儒家思想本身做了较为系统全面的研究 ，包括发展脉络、主要代表人物、经学研究、理学研究、三教合一思潮、金代的女真人与儒家思想文化、金代的孔庙与庙学、金代儒学特质等，较为完整地展现了金代儒家思想的整体风貌。.

Time-varying formation-containment problems for a second-order multiagent system are studied via pulse-modulated intermittent control in this paper. A distributed control framework utilizing the neighbors’ positions and velocities is designed so that leaders in the multiagent system form a formation, and followers move to the convex hull formed by each leader. Different from the traditional formation-containment problems, this paper applies the PMIC framework, which is more common and more in line with the actual control scenarios. Based on the knowledge of matrix (...) theory, algebraic graph theory, and stability theory, some sufficient conditions are given for the time-varying formation-containment problem of the second-order multiagent system. Some numerical simulations are proposed to verify the effectiveness of the results presented in this paper. (shrink)

ObjectiveThis study aims to investigate the effectiveness of mindfulness-based cognitive therapy combined with medication therapy in preventing the recurrence of major depressive disorder in convalescent patients.MethodsA total of 130 patients with convalescent MDD were enrolled in this prospective study. Sixty-five patients were assigned to the experimental group and received medication therapy combined with MBCT, and 65 patients were assigned to the control group and treated with medication alone. The recurrence rate and related hormonal changes were compared between the two groups.ResultsAfter (...) 1 year of MBCT intervention, eight patients experienced recurrence in the experimental group, a recurrence rate of 12.31%, and 19 patients experienced recurrence in the control group, a recurrence rate of 29.23%. The Hamilton Depression Rating Scale and the World Health Organization Quality of Life Scale scores in both the experimental and the control groups were significantly improved after treatment. The difference in the HAM-D scores before and after treatment in the experimental group was 16.74 ± 4.54; this was significantly higher than that of the control group. The WHOQOL-BREF scores in the experimental group were significantly improved compared with those of the control group. The differences in the levels of corticotrophin-releasing hormone, adrenocorticotropic hormone, and cortisol before and after treatment in the experimental group and the control group were statistically significant. The difference in CRH before and after treatment in the experimental group was 16.8 ± 7.2, which was higher than that of the control group. The intervention with MBCT had a significant impact on the recurrence of MDD [β = 1.206, P = 0.039, 95% CI = 0.0790–1.229]. The difference in the HAM-D scores also had a significant impact on the recurrence of MDD.ConclusionCompared with medication therapy alone, the use of MBCT combined with medication therapy can effectively prevent the recurrence of MDD in convalescent patients. (shrink)

We have refined entropy theory to explore the meaning of the increasing sequence data on nucleic acids and proteins more conveniently. The concept of selection constraint was not introduced, only the analyzed sequences themselves were considered. The refined theory serves as a basis for deriving a method to analyze non-coding regions (NCRs) as well as coding regions. Positions with maximal entropy might play the most important role in genome functions as opposed to positions with minimal entropy. This method was tested (...) in the well-characterized coding regions of 12 strains of Classical Swine Fever Virus (CSFV) and non-coding regions of 20 strains of CSFV. It is suitable to analyze nucleic acid sequences of a complete genome and to detect sensitive positions for mutagenesis. As such, the method serves to formulate the basis for elucidating the functional mechanism. (shrink)

Understanding the neural basis of schizophrenia (SZ) is important for shedding light on the neurobiological mechanisms underlying this mental disorder. Structural and functional alterations in the anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (DLPFC), hippocampus, and medial prefrontal cortex (MPFC) have been implicated in the neurobiology of SZ. However, the effective connectivity among them in SZ remains unclear. The current study investigated how neuronal pathways involving these regions were affected in first-episode SZ using functional magnetic resonance imaging (fMRI). Forty-nine patients (...) with a first-episode of psychosis and diagnosis of SZ—according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision—were studied. Fifty healthy controls (HCs) were included for comparison. All subjects underwent resting state fMRI. We used spectral dynamic causal modeling (DCM) to estimate directed connections among the bilateral ACC, DLPFC, hippocampus, and MPFC. We characterized the differences using Bayesian parameter averaging (BPA) in addition to classical inference (t-test). In addition to common effective connectivity in these two groups, HCs displayed widespread significant connections predominantly involved in ACC not detected in SZ patients, but SZ showed few connections. Based on BPA results, SZ patients exhibited anterior cingulate cortico-prefrontal-hippocampal hyperconnectivity, as well as ACC-related and hippocampal-dorsolateral prefrontal-medial prefrontal hypoconnectivity. In summary, spectral DCM revealed the pattern of effective connectivity involving ACC in patients with first-episode SZ. This study provides a potential link between SZ and dysfunction of ACC, creating an ideal situation to associate mechanisms behind SZ with aberrant connectivity among these cognition and emotion-related regions. (shrink)

Based on the existing financial system risk models, a set of time-lag financial system risk models is established considering the influence brought by time-lag factors on the financial risk system, and the dynamical behavior of this system is analyzed by using chaos theory. Through Matlab simulation, the bifurcation diagram and phase diagram of time-lag risk intensity and control intensity are plotted. The analysis shows that this kind of time-lag financial system risk model has complex dynamic behavior, different motion states will (...) appear when different parameter values are selected, and the time-lag risk intensity parameter also has a very strong influence on the system motion. To ensure the operation of the financial system in a stable state, measures with certain delay effects must be taken to control the risk and to choose the appropriate time-lag control intensity, and too much or too little time-lag control intensity is not conducive to the benign operation of the system. (shrink)

The twenty-first century is arguably the century of computing. In such a world saturated by computing, Computational Thinking is now recognized as a foundational competency for being an informed citizen and being successful in STEM work. Nevertheless, how to effectively import different types of teaching methods in university courses is subjected to further evaluation. Currently, the arguments in favor of tangible robots including high interaction, great practicality, and specific operation results make themselves to be often used as a teaching medium (...) and tool for teaching activities between teachers and students. Hence, in addition to cultivating students with computational thinking ability, this paper discussed how to integrate tangible robots into project-based learning courses of thinking skills training to improve the learning performance of the computational thinking ability. This study conducted in one semester on the 105 students from three classes. Experimental results show that the project-based learning method integrated with the teaching material of robotic visual programs approach had significantly better effectiveness in improving students' learning achievements than the traditional teaching method integrated with paper practice teaching materials approach. Analysis of the questionnaire results showed that the proposed learning approach did not increase the students' cognitive burden. In sum, the proposed approach helps students' learning achievement and cognitive load. (shrink)

This article presents an economic analysis of information good pricing and consumer welfare, and discusses the implications of price discrimination in the information economy. It argues that network externalities, coupled with information asymmetry, enable a dominant marketer to price unequally, extracting late adopters surplus to compensate for the loss from early adopters. In the short term, the minority early adopters benefit by paying less, but in the long term, the majority late adopters suffer by paying more. Considering that late adopters (...) are likely to be at a disadvantage in resources, this discriminatory pricing amounts to the poor subsidizing the rich. Based on this analysis, implications for consumer welfare are discussed. (shrink)

Out of 288 Hong Kong cancer patients, 92.3% include themselves in decision-making, 71% prefer joint decision-making: with family, with doctor, with doctor plus family, with family minus doctor, and with doctor minus family. <5% want decision-making by “doctor-alone” and <1% desire decision-making by “family-alone”. Harmony, communication and responsibility are reasons for family participation. Most patients prefer “specialist” for information, followed by “family”, “friends”, and “GP”. Trust in doctors and prospects for controlling/curing disease are important factors in decision-making. Patients want to (...) participate and be listened to rather than make decisions. Doctors should not disclose information to family without patients’ permission, nor withhold information from patient [End Page 109] on family’s request. Only 25% of patients have discussed post-competent treatment with others and 7% have heard of Advance Directive ; 24% refuse to discuss it. After AD has been explained to them, 66% remain reluctant to sign one, preferring to leave oral instructions or appoint family as proxy decision-makers. The family’s decision-making role increases when patients become incompetent. The top reason for signing AD is to receive preferred post-competent treatments, and for not signing it, difficulty with making a prospective decision. The implications of these findings will be discussed. (shrink)