Taiwan is an island country situated in the northwest Pacific, close to the southeast of China. The land area is about 36,000 square kilometers. The population of Taiwan is about 23 million, and it consists of the majority Han ethnic groups and dozens of minority groups who are collectively called “Formosan,” an appellation for indigenous peoples in Taiwan. Formosans can be divided into Pingpu and Gaoshan by their living area. In recent years, marriages between Taiwanese, Mainland Chinese, and Southeast Asians (...) have increased significantly. Because of the genetic background of the Taiwanese people, it was thought to be highly beneficial for Taiwan to establish a biobank specifically designed for the Taiwanese population, as it would enable large-scale cohort studies to be carried out for common diseases occurring in Taiwan. (shrink)

In the United States, final amendments to the Federal Policy for the Protection of Human Subjects (“the Common Rule”) were published on January 19, 2017, and they will take effect on January 21, 2019. One of the most widely discussed provisions is that for the first time, federal regulations governing research with humans authorize the use of broad consent for future, unspecified research on individually identifiable biospecimens and associated data. Many questions have been raised about broad consent, including what effect (...) it will have on research and whether it adequately protects the interests of research participants.There are lessons to be learned for the U.S. and other countries by looking to countries that already have experience with broad consent for biobank collection and with the storage and subsequent use of the biospecimens and data. This article describes how broad consent works in five countries—Canada (in Quebec), Israel, Nigeria, Taiwan, and the United Kingdom—and with different types of biobanks: national biobanks, federated biobanks, and regional biobanks. Evaluating the provisions and challenges of the broad consent approaches in these countries can inform policies for this increasingly used approach to biobank regulation. (shrink)

BackgroundThe therapeutic effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson's disease (PD) is related to the modulation of pathological neural activities, particularly the synchronization in the β band (13–35 Hz). However, whether the local β activity in the STN region can directly predict the stimulation outcome remains unclear.ObjectiveWe tested the hypothesis that low-β (13–20 Hz) and/or high-β (20–35 Hz) band activities recorded from the STN region can predict DBS efficacy.MethodsLocal field potentials (LFPs) were recorded in (...) 26 patients undergoing deep brain stimulation surgery in the subthalamic nucleus area. Recordings were made after the implantation of the DBS electrode prior to its connection to a stimulator. The maximum normalized powers in the theta (4–7 Hz), alpha (7–13 Hz), low-β (13–20 Hz), high-β (20–35 Hz), and low-γ (40–55 Hz) subbands in the postoperatively recorded LFP were correlated with the stimulation-induced improvement in contralateral tremor or bradykinesia–rigidity. The distance between the contact selected for stimulation and the contact with the maximum subband power was correlated with the stimulation efficacy. Following the identification of the potential predictors by the significant correlations, a multiple regression analysis was performed to evaluate their effect on the outcome.ResultsThe maximum high-β power was positively correlated with bradykinesia–rigidity improvement (rs = 0.549, p < 0.0001). The distance to the contact with maximum high-β power was negatively correlated with bradykinesia–rigidity improvement (rs = −0.452, p < 0.001). No significant correlation was observed with low-β power. The maximum high-β power and the distance to the contact with maximum high-β power were both significant predictors for bradykinesia–rigidity improvement in the multiple regression analysis, explaining 37.4% of the variance altogether. Tremor improvement was not significantly correlated with any frequency.ConclusionHigh-β oscillations, but not low-β oscillations, recorded from the STN region with the DBS lead can inform stimulation-induced improvement in contralateral bradykinesia–rigidity in patients with PD. High-β oscillations can help refine electrode targeting and inform contact selection for DBS therapy. (shrink)

Hung Yao-hsün is one of the most creative, albeit long overlooked, thinkers in Japanese-ruled Taiwan. This paper’s aim is threefold. It first argues that while Hung’s early philosophy was rooted in the Kyoto school, he is a key founder of the Sit-chûn movement of Taiwanese philosophy. It next shows that during Taiwan’s martial law, Hung’s thought features a “Buddhist turn,” in which Zen is incorporated within existentialism. Third, while this turn is a sharp contrast to his prewar philosophical activism, Hung’s (...) last work stressed Abraham Kaplan’s view that philosophy should be connected to one’s life experience, echoing Hung’s prewar usage of fūdo in justifying Taiwan’s cultural subjectivity. In other words, there is an implicit continuity between his early and late philosophy. (shrink)

This article attempts a new interpretation of Lao Tzu's metaphysics of Tao by employing a combined method of linguistic and philosophical analyses. This new methodological approach involves the following basic assumptions: (1) Lao Tzu's metaphysics of Tao can be characterized as a kind of non?dualistic and non?conceptual metaphysics sub specie aeternitatis; (2) Tao is not an entity, substance, God, Idee, or anything hypostatized or conceptualized, but is rather a metaphysical symbol unifying various dimensions of Nature as the totality of things?as?they?are; (...) (3) there is, generally speaking, no confusion or inconsistency of thought involved in the Lao?Tzu; (4) there are two kinds of speech used by Lao Tzu, viz. philosophical (real) speech and figurative (metaphorical) speech; and (5) figurative expressions, which predominate, can be reduced to philosophical expressions for the sake of the clarification of Lao Tzu's thought. In the light of these basic assumptions, a philosophical explication of Lao Tzu's conception of Tao is undertaken by exploring its six dimensions. They are: (i) Tao as Reality, (ii) Tao as Origin, (iii) Tao as Principle, (iv) Tao as Function, (v) Tao as Virtue, and (vi) Tao as Technique; and (ii)?(vi) can be subsumed under Tao as Manifestation (to us). These six dimensions are not ?categories? or ?attributes? in the Western (conceptual) sense, but are the inseparable aspects or perspectives of Tao reconstructed from the Lao?Tzu in order to show the best possible way of understanding Lao Tzu's metaphysical thinking. In the Epilogue, a brief comparison of Lao Tzu and Spinoza is made in order to emphasize the non?conceptual and non?propositional nature of Lao Tzu's metaphysical language. (shrink)

The Confucian tradition is often held to have accorded the family a prominent place in their ethics. This paper distinguishes three different senses in which the family is held to be primary in Confucian morality. It then explores Hsun Tzu's views on the family and familial relations. I argue that, while other early Confucians such as Confucius and Mencius would have held the family to be primary in all three senses, Hsun Tzu held the family to be primary (...) in only one of the three senses. In particular, there is textual evidence that Hsun Tzu holds that one's primary obligation is to the ruler of the state, rather than to the immediate family. (shrink)

HSÜN Tzu's essay on "Rectifying Terms" is justly considered a work of "great logical interest." For in this essay, one finds a remarkably modern concern with such topics as the rationale for having terms; the empirical and pragmatic bases for the classification of terms; the formation of generic and specific terms; the importance of observing established linguistic practices; the necessity of complying with proper standards for the institution, ratification, and regulation of the uses of language ; the nature of argumentative (...) discourse ; and the problems inherent in successful linguistic communication. A careful examination of some passages in other essays also suggests an awareness of the distinction between deductive, inductive, and analogical inferences, though Hsün Tzu provides us no explicit discussion of the nature of reasoning and its validating rules. (shrink)

This article takes one of the richest historical debates, that of Hsun-Tzu and Mencius, as the contextual starting-point for the elaboration of human goodness. In support of Mencius, this article develops additional metaphysical and bio-social-evolutionary grounds, both of which parallel each other. The metaphysical analysis suggests that, in the spirit of Spinoza, an entity’s nature must necessarily include the drive toward its preservation. Likewise, the multi-faceted bio-social-evolutionary argument locates the fundamental telos of humanity in the preservation of social ties (...) and species preservation, leading to a life-affirming philosophy and bio-psychological deduction of human emotions based on the primary emotion of love. (shrink)

The sources of "knowledge," for Hsün-tzu, came from the realities in objective existence. He took the impressions of these objectively existent realities as his basis of knowledge.

Hsün Tzu was an eminent Legalist. The book Hsün Tzu fully reflects his Legalist thought. In the decisive period of great social change at the end of the Warring States period he stood in the front ranks of the age and created a great deal of public opinion in favor of the replacement of the slave system by the feudal system; he "disclosed the past, set forth the present, dispersed disorder, and propagated reason as easily as turning over his hand" (...) , creating a thick foundation of theory for the Legalist line and manifesting the vital and vigorous fighting spirit of the newly rising landlord class. (shrink)

이 글은 순자의 인성론에 관한 연구라는 지극히 협소한 영역을 대상으로 한다. 만약 순자 사상의 전모를 파악하려 하거나 또는 일부분에 관한 정확한 이해를 도모하려 한다면, 당연히 순자 사상의 중요한 부분인 ‘禮’에 관한 입론도 심도 있게 다루어야 할 것이다. 그럼에도 불구하고 순자의 인성론을 문제 삼은 이유는, 그의 인성론에 대한 재검토가 ‘禮’ 사상의 고찰에 대해서 먼저 해결되어야 할 성격을 가진다 생각하기 때문이다. 따라서 재해석된 순자의 인성론을 통해서 그의 예론을 상세히 고찰한다면 순자사상에 대한 전체적이면서 일관된 이해가 가능할 것이라 필자는 기대한다. 아울러 이 글에서는 인성론과 (...) 도덕이론과의 일관된 관계성을 모색하는 선에서 논의를 마치고 예론의 구체적인 내용에 해당하는 실천· 수양론에 대한 연구는 차후의 일로 미룬다. (shrink)

The view of evil human nature is important in Chinese and western cultures. The thesis chooses evil human in St. Augustine’s thoughts and Hsun Tzu’s thoughts to compare and analyze evil in these two. St. Augustine, who is called “the Saint of God”, views the definition of evil, the resource of it, and salvations of it from the aspect of religious beliefs. He considers that evil is the privation of goodness and is not created by God. Because God is (...) omnipotent and all-good, it is impossible for God to create evil. Evil results from the free will of human beings themselves. If people want to attain their salvations, they should use their free will to choose good will and follow the goodness given by God. Hsun Tzu, one of Confucian scholars, puts forward evil human nature which is totally different from good human nature in Confucianism. He views the definition of evil, the source of it, and ways to change evil into good from the angle of social reality in Warring States Period. In Hsun Tzu’s views, evil results from the uninhibited extension of sound physical needs and desires for living. Hsun Tzu believes that human nature is evil and goodness comes from nurture, therefore, converting evil into good is to change human nature through nurturing. By further comparison and analysis, the thesis further looks into these two perspectives from their differences and similarities. It states their differences from five aspects: backgrounds, ways to change evil to good, categories, historical status, and positions of human beings. Apart from those, the thesis also refers to their similarities to complement the comparative analysis. From comparison and analysis, we can draw two conclusions: first, evil human nature from Hsun Tzu is simple in connotation and relatively objective compared with the view of St. Augustine; second, St. Augustine thinks that human beings are equal in front of evil, which has positive significance compared with the ideas posed by Hsun Tzu who insists on the distinction between saint and ordinary people, between monarchs and their subjects. (shrink)

Mo Tzu, Hsün Tzu, and Han Fei Tzu were three of the most important philosophers in ancient China. This collection of their basic writings points to three very different positions within in the spectrum of Chinese thought and reveals the diversity of of the Chinese intellectual tradition.Presenting the principle doctrines of Mo Tzu and his followers, early rivals of the Confucian school, this section includes writings on music, fatalism, Confucians, and "universal love" -the cornerstone of Mo-ist philosophyHsün Tzu provided the (...) dominant philosophical system of his day. Although basically Confucian, he differed with Mencius by asserting that the original nature of man is evil, and also expounded on such subjects as good government, military affairs, Heaven, and music.Representative of the Fachia, or Legalist, school of philosophy, the writings of Han Fei Tzu confront the issues of preserving and strengthening the state through strict laws of punishment and reward. His lessons remain timely as scholars continue to examine the nature and use of power. (shrink)

This book reprints an ancient Chinese work from the late Warring States period (3rd century BC) that contains stories and anecdotes exemplifying the carefree nature of the ideal Taoist sage. Chuang Tzu's philosophy represents the main current of Taoist teachings, and his text is widely regarded as both deeply insightful and a great achievement in the Chinese poetical essay form. The version presented was translated by Feng Yu-lan, the famous Chinese philosopher, who puts more emphasis on Chuang Tzu's philosophy than (...) do previous attempts. William James once said that every great philosopher has a personal vision. When one has grasped that vision, the whole system can be easily understood. And Crocé once said that the greater a philosophical system is, the simpler the central idea. Although the present translation is limited to the first seven chapters of Chuang Tzu's writings, it accurately conveys his main vision and ideas. (shrink)

Background Ethical dilemmas that arise in the clinical setting often require the collaboration of multiple disciplines to be resolved. However, medical and nursing curricula do not prioritize communication among disciplines regarding this issue. A common teaching strategy, problem-based learning, could be used to enhance communication among disciplines. Therefore, a university in southern Taiwan developed an interprofessional ethics education program based on problem-based learning strategies. This study described tutors’ experience teaching in this program. Aim To explore the phenomenon of teaching and (...) learning in interprofessional ethics education for medical and nursing students from the perspectives of tutors. Design Phenomenological qualitative research. Methods Medical and nursing students completed a 6-week interprofessional ethics education program moderated by either physician or nurse tutors. At the conclusion of the ethics education program, all 14 tutors were invited to participate in focus group interviews. Among them, six tutors (three nursing tutors and three physician tutors) participated in additional individual interviews. All of the contents from the focus group interviews and individual interviews were recorded and transcribed. Using the phenomenological approach, the phenomenon of teaching and learning in interprofessional ethics education were generated. Ethical consideration The study was approved by the Institutional Review Board. Findings Three themes emerged from the tutors' teaching perspectives, including the instructor’s motivation to teach, the use of narrative case scenarios, and the emphasis on improving interprofessional ethics communication. Discussion Problem-based learning creates an interprofessional communication platform in interprofessional ethics education. The phenomenon of value convergence between tutors and students, between different students’ professions, and between different students’ professional maturities is observed. Conclusion Problem-based learning is an effective teaching strategy for creating a communication platform for interprofessional ethics education. Ethic curriculum should emphasize motivating instructor, use narrative case scenarios, and focus on interprofessional communication. (shrink)