As is well known, Frege gave an explicit definition of number (belonging to some concept) in ?68 of his Die Grundlagen der Arithmetik.

One of the remarkable results of Frege’s Logicism is Frege’s Theorem, which holds that one can derive the main truths of Peano arithmetic from Hume’s Principle (HP) without using Frege’s Basic Law V. This result was rediscovered by the Neo-Fregeans and their allies. However, when applied in developing a more advanced theory of mathematics, their fundamental principles—the abstraction principles—incur some problems, e.g., that of inflation. This paper finds alternative paths for such inquiry in extensionalism and object theory.

Why Can a Japanese Unagi-Sentence Be Used in a Request? The objective of this paper is to reveal why the so-called Unagi-sentence in Japanese can be widely used in the context of request within the framework of cognitive linguistics and cognitive pragmatics. The Unagi-sentence, which is known as a representative sentence of the Japanese language, has been analyzed for years in various manners from various viewpoints. For instance, the sentence "Boku-wa Unagi-da" when literally translated into English reads I am an (...) eel. One of the most influential reasons for this sentence being regarded as characteristic to Japanese seems to be the clear difference in the sense in that the literally translated version in English means the identification between I and an eel, whereas the Unagi-sentence in Japanese indicates who orders the eel dish or sometimes requests the waiter to put a proper dish in a proper place. This thesis discusses the schematic meaning of the "X-wa Y-da" pattern in Japanese; further, it discusses the tendency for the Japanese language, unlike English, to depend more heavily on contextual information when the construed mental images are encoded. Through the discussion, I will reveal that the study of the Unagi-sentence from the viewpoint of cognitive linguistics sheds a new light on the contrastive studies in the field of pragmatics. (shrink)

隠す心理をテーマに,社会・発達・認知・生理・動物心理学の領野から12の話題を厳選。心を科学的に探究する面白さへと誘う書。.

The sophisticated function of the central nervous system (CNS) is largely supported by proper interactions between neural cells and blood vessels. Accumulating evidence has demonstrated that neurons and glial cells support the formation of blood vessels, which in turn, act as migratory scaffolds for these cell types. Neural progenitors are also involved in the regulation of blood vessel formation. This mutual interaction between neural cells and blood vessels is elegantly controlled by several chemokines, growth factors, extracellular matrix, and adhesion molecules (...) such as integrins. Recent research has revealed that newly migrating cell types along blood vessels repel other preexisting migrating cell types, causing them to detach from the blood vessels. In this review, we discuss vascular formation and cell migration, particularly during development. Moreover, we discuss how the crosstalk between blood vessels and neurons and glial cells could be related to neurodevelopmental disorders. (shrink)

Both W9 and OP3‐4 were known to bind the receptor activator of NF‐κB ligand (RANKL), inhibiting osteoclastogenesis. Recently, both peptides were shown to stimulate osteoblast differentiation; however, the mechanism underlying the activity of these peptides remains to be clarified. A primary osteoblast culture showed that rapamycin, an mTORC1 inhibitor, which was recently demonstrated to be an important serine/threonine kinase for bone formation, inhibited the peptide‐induced alkaline phosphatase activity. Furthermore, both peptides promoted the phosphorylation of Akt and S6K1, an upstream molecule (...) of mTORC1 and the effector molecule of mTORC1, respectively. In the in vivo calvarial defect model, W9 and OP3‐4 accelerated BMP‐2‐induced bone formation to a similar extent, which was confirmed by histomorphometric analyses using fluorescence images of undecalcified sections. Our data suggest that these RANKL‐binding peptides could stimulate the mTORC1 activity, which might play a role in the acceleration of BMP‐2‐induced bone regeneration by the RANKL‐binding peptides. (shrink)

Index to the Dhammasangani. Compiled by Tetsuya Tabata, Satoshi Nonome and Shoko Bando. Pali Text Society, London 1987. vii, 128 pp. £8.75.