In December 1924 when Simone de Beauvoir almost certainly wrote her essay analyzing Claude Bernard's "Introduction to the Study of Experimental Medicine," a classic text in the philosophy of science, she was a 16 yr old student in a senior-level philosophy class at a private Catholic girls' school. Given the popular conception of existentialism as anti science, Beauvoir's early interest in science, reflected in her baccalaureate successes as well as her paper on Bernard, may be surprising. But her enthusiasm for (...) Bernard is unmistakable. We have identified three themes in Beauvoir's essay that reappear in her later work, including the valuing of philosophical doubt. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. (...) The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on September 1 and 2, 2020 (Zoom Video Communications) due to restrictions related to the COVID-19 pandemic. The meeting focused on advances in: (1) optogenetics as a tool for comprehending neurobiology of diseases and on optogenetically-inspired DBS, (2) cutting edge of emerging DBS technologies, (3) ethical issues affecting DBS research and access to care, (4) neuromodulatory approaches for depression, (5) advancing novel hardware, software and imaging methodologies, (6) use of neurophysiological signals in adaptive neurostimulation, and (7) use of more advanced technologies to improve DBS clinical outcomes. There were 178 attendees who participated in a DBS Think Tank survey, which revealed the expansion of DBS into several indications such as obesity, post-traumatic stress disorder, addiction and Alzheimer’s disease. This proceedings summarizes the advances discussed at the Eighth Annual DBS Think Tank. (shrink)

DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

In a recent paper, Michael Huemer provides a new interpretation for ‘N’, the operator that occurs in Peter van Inwagen’s Consequence Argument, and argues that, given that interpretation, the Consequence Argument is sound. I have no quarrel with Huemer’s claim that the Consequence Argument is valid. I shall argue instead that his defense of its premises—a defense that allegedly involves refuting David Lewis’s response to van Inwagen—is unsuccessful.

A major preoccupation of that novel [Zola’s Nana] is the undressing of the courtesan Nana. One could even say that a major dynamic of the novel is stripping Nana, and stripping away at her, making per progressively expose the secrets of this golden body that has Paris in thrall. The first chapter of the novel provides, quite literally, a mise-en-scène for Nana’s body, in the operetta La Blonde Vénus. When she comes on stage in the third act, a shiver passes (...) over the audience, for, we are told, she is nude. Yet, we quickly discover, not quite nude: she is covered by a filmy shift under which her splendid body lets itself be glimpsed: se devinait. “It was Venus born from the waves, having only her hair as a veil.”2 The denuding of nana progresses in chapter 5 when Comte Muffat and the Prince make their way backstage to her dressing room . They surprise her naked to the waist, and she then covers herself with a bodice, which only half hides her breasts. Despite the repeated references to nana as nude, it is only in chapter 7, at the very midpoint of the novel, that Nana is finally completely naked. In this scene, she undresses before her mirror while Comte Muffat watches, especially looking at her looking at herself. Thus she is fully unveiled, frontally in the mirror, and from the backside in Muffat’s direct view. And yet, as we shall see in a moment, even the completely naked woman’s body bears a troubling veil. 2. Émile Zola, Nana , p. 47; hereafter abbreviated N. I wish to thank Helen Chillman, Librarian of the Slides and Photography Collection, Art and Architecture Library, Yale University, for her help in assembling the illustrations accompanying this essay.Peter Brooks is Tripp Professor of Humanities and Director of the Whitney Humanities Center at Yale University. The author of The Melodramatic Imagination and Reading for the Plot , he is currently working on a study of narrative and the body, tentatively called “Storied Bodies.”. (shrink)

This dissertation presents a new interpretation of Rene Descartes' views on body/body causation by examining them within their historical context. Although Descartes gives the impression that his views constitute a complete break with those of his predecessors, he draws on both Scholastic Aristotelian concepts of the efficient cause and existing anti-Aristotelian views. ;The combination of Aristotelian and anti-Aristotelian elements in Descartes' theory of causation creates a tension in his claims about the relationship between the first cause, God, and the secondary (...) causes, created things. To make sense of Descartes' position on secondary causation I study the 16th and 17th century debates on secondary causation, God's concurrence, and the action of efficient causes. I examine the Aristotelian commentaries of the Jesuit philosophers Francisco Suarez, Francisco Toledo, Antonio Rubio and the Coimbran Commentators. I also analyze the anti-Aristotelian views on nature and causation found in Sebastian Basson's textbook on natural philosophy. ;The Jesuit philosophers, like Descartes, deny that the extendedness and impenetrability of matter requires the existence of occult forces to penetrate the matter and exercise causality. Rather they argue that causality is exercised by a thing's form and that causal interaction requires only contiguity not penetration. They also downplay the importance of the final cause, making the efficient cause prior in the study of nature. While Descartes rejects their hylomorphism, he agrees with the Jesuits that there are secondary efficient causes which determine God's action, causing a specific kind of effect. However, for Descartes the secondary causes are the laws of nature, not individual substances. ;Descartes' reduction of all natural change to the local motion of material particles is reminiscent of Basson's anti-Aristotelian natural philosophy. Basson reacts against the Jesuit view of secondary causation, arguing that it commits them to attributing cognition to physical causes. His own account of natural causation contains both mechanistic elements, which we find in a more developed form in Descartes' philosophy, and Neoplatonic and Stoic elements which Descartes rejects. (shrink)

Individuals living with rare conditions are faced with important challenges derived from the rarity of their conditions and aggravated by the low priority given to rare disease research. However, current realities of rare disease research require consideration of the relationship between subjectivity and ‘traditional’ objectivity. Objectivity in research has traditionally been associated with processes and descriptions that are independent of the investigator. The need for researchers to provide unbiased knowledge and achieve a balance between objectivity and the underlying values in (...) nursing and scientific research requires an examination of how objectivity is conceptualized within the context of rare disease research. The aim of this paper is to examine scientific objectivity in rare disease research from a philosophical viewpoint and, in doing so, demonstrate the need to redefine it to reflect the current scientific environment. As such, healthcare providers working on this field need to redefine objectivity around ethical and moral obligation to advance science in an equitable manner with the end goal to produce knowledge that is trustworthy and beneficial to our patients. (shrink)

The field of educational leadership is multi-site, in which those who study and practice leadership are located within networks which connect across institutions and sectors. Charting the growth of this dynamic field is the central purpose of this paper and six interconnected typologies of knowledge production are presented: Producers, Positions, Provinces, Practices, Processes and Perspectives. We argue that these typologies enable those involved to generate descriptions and understandings of the interplay between researching, theorising and practising in educational settings. This focus (...) on knowledge production enables us to be mappers, to undertake mapping and to produce maps. These, we would stress, are all political processes through which we challenge what is said to be known and make our own claims to know. As such our agency to make choices within our practice as researchers, theorists, and practitioners is exercised within a complex setting of organisational, cultural and social structures. (shrink)

Background:While there have been studies exploring moral habitability and its impact on the work environments of nurses in Western countries, little is known about the moral habitability of the work environments of nurses and midwives in resource-constrained settings.Research objective:The purpose of this research was to examine the moral habitability of the work environment of nurses and midwives in Ghana and its influence on their moral agency using the philosophical works of Margaret Urban Walker.Research design and participants:A critical moral ethnography was (...) conducted through the analysis of interviews with 30 nurses and midwives, along with observation, and documentary materials.Ethical considerations:After receiving ethics approval, signed informed consent was obtained from participants before data collection.Results:Five themes were identified: (1) holding onto the values, identities, and responsibilities of being a midwife/nurse; (2) scarcity of resources as limiting capacity to meet caring responsibilities; (3) gender and socio-economic inequities shaping the moral-social context of practice; (4) working with incoherent moral understandings and damaged identities in the context of inter- and intra-professional relationships; and (5) surviving through adversity with renewed commitment and courage.Discussion:The nurses and midwives were found to work in an environment that was morally uninhabitable and dominated by the scarcity of resources, overwhelming and incoherent moral responsibilities, oppressive conditions, and workplace violence. These situations constrained their moral agency and provoked suffering and distress. The nurses and midwives negotiated their practice and navigated through morally uninhabitable work environment by holding onto their moral values and commitments to childbearing women.Conclusion:Creating morally habitable workplaces through the provision of adequate resources and instituting interprofessional practice guidelines and workplace violence prevention policies may promote safe and ethical nursing and midwifery practice. (shrink)

The present paper tries to trace the particular contours that the problem of theodicy assumes in the Chinese Buddhist text the Awakening of Faith in the Great Vehicle. It analyses the beginning section of the main body of text – the section, that is, that outlines the major theoretical structure of the work – in terms of a problem that has been of particular concern in western theology. I believe that taking such a tack is especially valuable for highlighting the (...) central Problematik around which the text is organized. The paper will thus use the problem of theodicy as a means of exploring some of the philosophical implications of the Awakening of Faith. (shrink)

Skeptical theists are seeking for some reasonable solutions to the evidential problem of evil. One of the most fundamental responses of skeptical theism is that the concept of “gratuitous evil”, which cannot be a proof of the absence of God. Therefore, it is not the existence of God that skeptical theism suspects. Instead, skeptical theism contemplates whether the evil in the world really has a “gratuitous” basis. This paper focuses on Peter van Inwagen's “no-minimum claim”. No-minimum claim” stands in opposition (...) to the views that assume that God minimizes the evils that exist in the world in order to achieve justice. “No-minimum claim” acknowledges that these evils still have enormous amounts to people. Thus “no-minimum claim” suggests that the evils experienced in the world are incompatible with the “best of all possible worlds” views or the other explanations of classical theodicy. According to the “no minimum claim”, the reason why the amount of evil in the world still seems so high may be God’s deliberate calculations in effecting the distribution of these evils. In order to reach these calculations, it is not necessary for the amount of evil that God allowed to reflect on the world to be perfectly manifested at the minimum level. The purpose of this paper is to consider the skeptical theism approach within the framework of Peter van Inwagen's “no-minimum claim” and to limit his arguments to an alternative approach to skeptic theism. Our claim is that such view coincides with skeptical theism, but the “no- minimum claim” still has some ambiguities at the point of the limits of evil. From this, we can conclude that the “no minimum claim” has received many objections in the skeptical theism literature and these objections are justified at certain points. (shrink)

Causation is a central topic in many areas of philosophy. In metaphysics, philosophers want to know what causation is, and how it is related to laws of nature, probability, action, and freedom of the will. In epistemology, philosophers investigate how causal claims can be inferred from statistical data, and how causation is related to perception, knowledge and explanation. In the philosophy of mind, philosophers want to know whether and how the mind can be said to have causal efficacy, and in (...) ethics, whether there is a moral distinction between acts and omissions and whether the moral value of an act can be judged according to its consequences. And causation is a contested concept in other fields of enquiry, such as biology, physics, and the law. This book provides an in-depth and comprehensive overview of these and other topics, as well as the history of the causation debate from the ancient Greeks to the logical empiricists. The chapters provide surveys of contemporary debates, while often also advancing novel and controversial claims; and each includes a comprehensive bibliography and suggestions for further reading. The book is thus the most comprehensive source of information about causation currently available, and will be invaluable for upper-level undergraduates through to professional philosophers. (shrink)

In their own words, many of the world's foremost mathematicians discuss the art and practice of their work in this book, which shines a light on some of the issues of mathematical creativity. It is neither a philosophical treatise nor the presentation of experimental results, but a compilation of reflections from top-calibre working mathematicians. This approach highlights the creative aspects of the field, illustrates the dramatic variation by individual, and hopes to express the vibrancy of creative minds at work. Organised (...) alphabetically, this book is meant for a general audience and is best read by browsing. It can be used as a supplementary text in mathematics history and mathematics education courses. (shrink)

In this special issue of Human Nature we explore the possible adaptive links between teaching and learning during childhood, and we aim to expand the dialogue on the ways in which the social sciences, and in particular current anthropological research, may better inform our shifting understanding of how these processes vary in different social and ecological environments. Despite the cross-disciplinary trend toward incorporating more behavioral and cognitive data outside of postindustrial state societies, much of the published cross-cultural data is presented (...) as stand-alone population-level studies, making it challenging to extrapolate trends or incorporate both ecological and developmental perspectives. Here, contributors explore how human life history, ecological experience, cumulative culture, and ethnolinguistics impact social learning and child development in foraging and transitioning societies around the world. Using historical ethnographic data and qualitative and quantitative data from studies with contemporary populations, authors interrogate the array of factors that likely interact with cognitive development and learning. They provide contributions that explore the unique environmental, social, and cultural conditions that characterize such populations, offering key insights into processes of social learning, adaptive learning responses, and culture change. This series of articles demonstrates that children are taught culturally and environmentally salient skills in myriad ways, ranging from institutionalized instruction to brief, nuanced, and indirect instruction. Our hope is that this collection stimulates more research on the evolutionary and developmental implications associated with teaching and learning among humans. (shrink)

This white paper outlines the plans of the History Philosophy Culture Working Group of the Next Generation Event Horizon Telescope Collaboration.

Happiness in World History traces ideas and experiences of happiness from early stages in human history, to the maturation of agricultural societies and their religious and philosophical systems, to the changes and diversities in the approach to happiness in the modern societies that began to emerge in the 18th century. In this thorough overview, Peter N. Stearns explores the interaction between psychological and historical findings about happiness, the relationship between ideas and popular experience, and the opportunity to use historical analysis (...) to assess strengths and weaknesses of dominant contemporary notions of happiness. Starting with the advent of agriculture, the book assesses major transitions in history for patterns in happiness, including the impact of the great religions, the unprecedented Enlightenment interest in secular happiness and cheerfulness, and industrialization and imperialism. The final, contemporary section covers fascist and communist efforts to define alternatives to Western ideas of happiness, the increasing connections with consumerism, and growing global interests in defining and promoting well-being. Touching on the experiences in the major regions of Asia, Africa, Latin America, Europe, and North America, the text offers an expansive introduction to a new field of study. This book will be of interest to students of world history and the history of emotions. (shrink)

Arthur Norman Prior (1914-69) was a logician and philosopher from New Zealand who contributed crucially to the development of ‘non-standard’ logics, especially of the modal variety. His greatest achievement was the invention of modern temporal logic, worked out in close connection with modal logic. However, his work in logic had a much broader scope. He was also the founder of hybrid logic, and he made important contributions to deontic logic, modal logic, the theory of quantification, the nature of propositions and (...) the history of logic. In addition, he discussed questions of ethics, free will, and general theology. Prior’s philosophical works comprise about 200 titles. His earliest articles center on philosophical theology and historical studies of Scottish Reformed Theology. This led on to the publication of his first influential work on ethics: Logic and The Basis of Ethics (1949). With the invention of tense-logic in the early 1950s, his focus shifted to investigations into the syntax of tempo-modal logic leading to his seminal Time and Modality (1957), a volume derived from his John Locke Lectures in Oxford in 1956. Furthermore Prior, together with the Irish mathematician and logician C.A. Meredith (1904-76), made important early contributions to the semantics of possible worlds. Prior’s tense-logic provided a strong conceptual framework for problems pertaining to the philosophy of time. In Time and Modality, Prior discussed the philosophical implications of Ruth Barcan’s famous formulae for tense-logic, and in the 1960s he worked on the notion of the present. The most persistent problem running through Prior’s work is his study of the questions surrounding human freedom and divine foreknowledge, and more general philosophical problems emerging from this classical theological question. His thorough analysis of this problem, with the conceptual tools of tense-logic, received a crucial impetus from his correspondence with the young Saul Kripke, when the latter suggested the semantic tool of branching time to Prior. Prior’s development of two solutions based on branching time for the problem of future contingency, the Peircean and the Ockham solution, was most thoroughly developed in Past, Present and Future (1967), the most important work published by Prior. Characteristically for Prior’s methodological approach, the development of these two solutions were at the same time a development of two new systems of tense logic, and vice versa. One of Prior’s significant contributions to logic was his work on world propositions and instant propositions. In the course of developing these notions he also made one of the earliest formulations of hybrid logic. In Papers on Time and Tense (1968), he presented this idea in a more detailed manner in the context of his four grades of tense-logical involvement. (shrink)

Define ‘het’ as a predicate that truly applies to itself if and only if it does not truly apply to itself and which also truly applies to any predicate that does not truly apply to its own name. We know that the attempted definition of ‘hes’ is a failure, and so a fortiori is that of ‘het’. Similarly, there is no Qussell class which contains itself as a member if and only if it does not contain itself as a member, (...) so a fortiori there is no Russell Class which contains itself as a member if and only if it does not contain itself as a member and which also contains all and only non-self-membered classes (such as the class of dogs). The second conjunct in both the definition of ‘het’ and of the Russell class cannot revive a definition doomed to failure. Likewise, the ‘definition’ of n as ‘n > 1 iff n < 1’ fails, and the attempted definition of m as ‘m > 1 iff m < 1 and m is prime’ is hopeless too; its final clause buys it no respectability. (shrink)

Hai, Peter NV Lay people have always played a vital role in the life and mission of the church but it is only after the Second Vatican Council that the question of the laity has come into focus in a new way in Catholic theological reflection. Indeed, in the wake of Vatican II, the council that introduced a Copernican shift in the Catholic understanding of the laity, lay people have become the theme of a Synod of Bishops, the subject of (...) an Apostolic Exhortation, and the topic of several pastoral statements of national conferences of bishops. This paper begins with a review of the state of the question highlighting the need for a comparative investigation of the theologies of the laity according to John Paul II, the Federation of Asian Bishops' Conferences, and the Vietnamese Episcopal Conference. It then highlights the differences and convergences in these theologies. As all three theologies draw their inspiration from the teachings of Vatican II, and a prominent element of the council's concerns was the emphasis on the universal call to holiness, we will also provide a detailed comparison of this notable aspect across these theological systems. Our argument is that while some minor points of divergence and disagreement remain there is a greater convergence and agreement between these theologies of the laity. (shrink)

The theme of this book is the crisis of the early modern state in eighteenth-century Britain. The revolt of the North American colonies and the simultaneous demand for wider religious toleration at home challenged the principles of sovereignty and obligation that underpinned arguments about the character of the state. These were expressed in terms of the 'common good', 'necessity', and 'community' - concepts that came to the fore in early modern European political thought and which gave expression to the problem (...) of defining legitimate authority in a period of increasing consciousness of state power. The Americans and their British supporters argued that individuals ought to determine the common good of the community. A new theory of representation and freedom of thought defines the cutting edge of this revolutionary redefinition of the basic relationship between individual and community. (shrink)

Experimental philosophers have gathered impressive evidence for the surprising conclusion that philosophers' intuitions are out of step with those of the folk. As a result, many argue that philosophers' intuitions are unreliable. Focusing on the Knobe Effect, a leading finding of experimental philosophy, we defend traditional philosophy against this conclusion. Our key premise relies on experiments we conducted which indicate that judgments of the folk elicited under higher quality cognitive or epistemic conditions are more likely to resemble those of the (...) philosopher. We end by showing how our experimental findings can help us better understand the Knobe Effect. (shrink)