We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

Functional theories posit that emotions are elicited by particular goal-related situations that represented adaptive problems and that emotions are evolved features of coordinated responses to those situations. Yet little theory or research has addressed the evolutionary aspects of these theories. We apply five criteria that can be used to judge whether features are adaptations. There is evidence that sadness, anger, and anxiety relate to unique changes in physiology, cognition, and behavior, those changes are correlated, situations that give rise to emotions (...) are consistent, and emotions are complex. To date, there is little experimental evidence regarding whether discrete emotions resolve adaptive problems and do so relatively efficiently. Evidence supporting all criteria is required to claim that discrete emotions are evolved features. (shrink)

Emotion Review, Volume 14, Issue 2, Page 114-116, April 2022. The question “what is emotion?” has long been at the core of theoretical debates. The IAC-E is a useful framework for understanding relationships among responses in emotional situations. However, this approach cannot address the nature of emotion. Researchers determine what counts as emotion in the IAC-E, and this decision impacts the relationships detected and inferences made. The assumptions of researchers about emotion change the output. Further, the model is not theoretically (...) agnostic and is best suited to examine emotion perception/knowledge, as in the simulations presented. According to some theories, experienced emotion is qualitatively different than situations that involve perceiving others' emotion or semantic knowledge. Addressing the nature of emotion requires empirical examination of the assumptions made in each theory. (shrink)

Emotion Review, Ahead of Print. The question “what is emotion?” has long been at the core of theoretical debates. The IAC-E is a useful framework for understanding relationships among responses in emotional situations. However, this approach cannot address the nature of emotion. Researchers determine what counts as emotion in the IAC-E, and this decision impacts the relationships detected and inferences made. The assumptions of researchers about emotion change the output. Further, the model is not theoretically agnostic and is best suited (...) to examine emotion perception/knowledge, as in the simulations presented. According to some theories, experienced emotion is qualitatively different than situations that involve perceiving others' emotion or semantic knowledge. Addressing the nature of emotion requires empirical examination of the assumptions made in each theory. (shrink)

The relationship between humans and animals is complex and influenced by multiple variables. Humans display a remarkably flexible and rich array of social competencies, demonstrating the ability to interpret, predict, and react appropriately to the behavior of others, as well as to engage others in a variety of complex social interactions. Developing computational systems that have similar social abilities is a critical step in designing robots, animated characters, and other computer agents that appear intelligent and capable in their interactions with (...) humans and each other. Further, it will improve their ability to cooperate with people as capable partners, learn from natural instruction, and provide intuitive and engaging interactions for human partners. Thus, human−animal team analogs can be one means through which to foster veridical mental models of robots that provide a more accurate representation of their near-future capabilities. Some digital twins of human−animal teams currently exist but are often incomplete. Therefore, this article focuses on issues within and surrounding the current models of human−animal teams, previous research surrounding this connection, and the challenges when using such an analogy for human−autonomy teams. (shrink)

Analytic processes reduce biases, but it is not known how or when these processes will be deployed. Based on an affective signal hypothesis, relatively strong affective reactions were expected to result in increased analytic processing and reduced bias in judgement. The valence and strength of affective reactions were manipulated through varying outcomes in a game or evaluative conditioning of a stimulus. Relatively strong positive or negative affective reactions resulted in less desirability bias. Bias reduction only occurred if participants had time (...) to deploy analytic processes and indicators of the degree of analytic processing (in the form of attentional control) predicted less bias. Affective processes have long been acknowledged as a source of bias, but these findings suggest affective processes are also integral to bias reduction. (shrink)

Political polarisation in the United States offers opportunities to explore how beliefs about candidates – that they could save or destroy American society – impact people’s thoughts, feelings, and behaviour. Participants forecast their future emotional responses to the contentious 2020 U.S. presidential election, and reported their actual responses after the election outcome. Stronger beliefs about candidates were associated with forecasts of greater emotion in response to the election, but the strength of this relationship differed based on candidate preference. Trump supporters’ (...) forecast happiness more strongly related to beliefs that their candidate would save society than for Biden supporters. Biden supporters’ forecast anger and fear were more strongly related to beliefs that Trump would destroy society than vice versa. These forecasts mattered: predictions of lower happiness and greater anger if the non-preferred candidate won predicted voting, with Biden supporters voting more than Trump supporters. Generally, participants forecast more emotion than they experienced, but beliefs altered this tendency. Stronger beliefs predicted experiencing more happiness or more anger and fear about the election outcome than had been forecast. These findings have implications for understanding the mechanisms through which political polarisation and rhetoric can influence voting behaviour. (shrink)

Awe and wonder are theorised to be distinct from other positive emotions, such as happiness. Yet little empirical or theoretical work has focused on these emotions. This investigation explored differences in language used to describe experiences of awe and wonder. Such analyses can provide insight into how people conceptualise these emotional experiences, and whether they conceptualise these emotions to be distinct from other positive emotions, and each other. Participants wrote narratives about experiences of awe, wonder and happiness. There were differences (...) in the language used to describe these positive emotional states, consistent with the theorised functions of each emotion. Awe was related to observing the world, reflected in greater use of perception words. Wonder was related to trying to understand the world, reflected in greater use of cognitive complexity and tentative words. Language use for both emotions reflected an environmental focus, whereas language use for happiness reflected a social/relationship focus. (shrink)

This research examined how individuals' motivations and goals were related to their memory for past emotional experiences. In two studies, participants rated how happy and anxious they felt while completing a challenging anagram task and later recalled their emotions. Bias in memory for emotions was predicted by the combination of participants' general motivation (approach BAS vs. avoidance BIS) and the specific goal they set for the task (approach vs. avoidance). Participants with approach motivation and goals overestimated happiness more, and showed (...) a stronger relation between peak and remembered happiness, than other participants. Participants with avoidance motivation and goals overestimated anxiety more, and showed a stronger relation between peak and remembered anxiety, than other participants. Thus motivational factors known to influence attention to valenced information also predict how emotional experiences will be remembered. (shrink)

The central idea of this paper is that Michel Foucault and Søren Kierkegaard are unexpected allies in the investigation into the relation between madness and reason. These thinkers criticize reason’s presumption of purity and call into question reason’s isolation from madness. Strategies of indirect communication and regard for paradox from Kierkegaard’s nineteenth-century works find new ground in Foucault’s twentieth-century archaeological undertaking as Foucault illuminates “both-and” moments in the history of madness, uncovering points where rationalism paradoxically conceives of madness or where (...) madness is not unreasonable. Furthermore, for both thinkers, form and content meet, as Kierkegaard and Foucault’s occasionally “delirious lyricism” (in the phrase of Dominick LaCapra) exemplifies the intertwining of logical and illogical forces. (shrink)

A meta-analytic review of studies that experimentally elicited awe and compared the emotion to other conditions (84; 487 effects; 17,801 participants) examined the degree to which experimentally elicited awe (1) affects outcomes relative to other positive emotions (2) affects experience, judgment, behaviour, and physiology, and (3) differs in its effects if the awe state was elicited through positive or threatening contexts. The efficacy of methods that have been used to experimentally elicit awe and the possibility of assessing changes in the (...) state of the self with experimental awe elicitations were also examined. Meta-analyses with robust variance estimation revealed that awe affected outcomes compared to other positive emotions and control conditions; affected experience, judgment, and behaviour; and had similar effects if elicited through positive or threatening contexts. The ability to compare awe to negative emotion states and its effects on physiology was limited by a small number of available effects. Images, videos, autobiographical recall, and naturalistic exposure were effective in eliciting awe. Exploratory analyses suggested that some processes involved in changes in the self can be related to experimental awe elicitations. These findings suggest awe is a discrete emotion and identifies areas for future investigation. (shrink)

This study was designed to compare the natural free form communication that takes place when a person interacts with robotic entities versus live animals. One hundred and eleven participants interacted with one of four entities: an AIBO robotic dog, Legobot, Dog or Cat. It was found that participants tended to rate the Dog as more capable than the other entities, and often spoke to it more than the robotic entities. However, participants were not positively biased toward live entities, as the (...) Cat often was thought of and spoken to similarly to the AIBO robot. Results are consistent with a model in which both appearance and interactivity lead to the development of beliefs about a live or robotic entity in an interaction. Keywords: Human-robot interaction; human-animal interaction; AIBO; free form communication; attributions; human-entity interaction. (shrink)

When recalling autobiographical memories, individuals often experience visual images associated with the event. These images can be constructed from two different perspectives: first person, in which the event is visualized from the viewpoint experienced at encoding, or third person, in which the event is visualized from an external vantage point. Using a novel technique to measure visual perspective, we examined where the external vantage point is situated in third-person images. Individuals in two studies were asked to recall either 10 or (...) 15 events from their lives and describe the perspectives they experienced. Wide variation in spatial locations was observed within third-person perspectives, with the location of these perspectives relating to the event being recalled. Results suggest remembering from an external viewpoint may be more common than previous studies have demonstrated. (shrink)

In this response to Robert Hudson’s article, “Should We Strive to Make Science Bias-Free? A Philosophical Assessment of the Reproducibility Crisis,” we identify three ways in which he misrepresents our work: he conflates value-ladenness with bias; he describes our view as one in which values are the same as evidential factors; and he creates a false dichotomy between two ways that values could be considered in science for policy. We share Hudson’s concerns about promoting scientific reproducibility and reducing bias in (...) science, but we reject his view that the value-free ideal provides helpful guidance for addressing these issues. (shrink)

Paideia is a word that signifies education or culture—two concepts that are only apparently distinct in Ancient Greek thinking. The performance of poetry, philosophy, rhetoric, drama, dance, and even athletics functioned simultaneously as education and culture. They entertained and unified communities by affirming shared heritage and interrogating common values. This process had special importance in Sicily and Southern Italy, where Hellenism was often a matter of education rather than ancestry. This volume explores the intersection of education and cultural performance in (...) a variety of disciplines and from a variety of perspectives. Authors discussed include Sappho, Empedocles, Gorgias, Plato, and Aristotle. Contexts range from choral dance, to epideictic oratory, theatrical performance, philosophical dialogue, and gymnastic exercise. Taken together, these diverse essays reveal a cultural paideia aimed at realizing an ideal of human potential—not least by questioning human reality. Edited by Henry C. Curcio, Mark Ralkowski, and Heather L. Reid, the volume includes essays by Audrey L. Anton & Erika N. Brown, Paloma Flávio Betini, Michał Bizoń, L.M.J. Coulson, Mateo Duque, Jurgen R. Gatt & Andrew Debono Cauchi, Michael Goyette, Veronika Konrádová, Georgios Mouratidis & Heather L. Reid, Kristian Sheeley, and Colin C. Smith. (shrink)

The acquisition of fully informed consent presents a central ethical problem for the procurement and storage of human tissue in biobanks. The tension lies between the apparent necessity of obtaining informed consent from potential research subjects and the projected future use of the tissue. Specifically, under the doctrine of informed consent medical researchers are required to inform their potential research subjects about the relevant risks and purposes of the proposed research (Declaration of Helsinki, 2008, “Section 24.” Accessed November 1, 2009. (...) http://www.wma.net/en/30publications/10policies/b3/index.html). However, because human tissue – when stored in biobanks – can be put to multifarious uses, the information that medical researchers are expected to divulge to their subjects is epistemologically inaccessible. Biobank researchers are thus thought to be unable to obtain informed consent from their subjects, making the practice ethically suspicious. We propose that such suspicions of ethical failure should be reconsidered by presenting two possible solutions. Firstly we argue that the epistemological difficulty might be partially solved by adopting the “waiver model” of informed consent. Secondly, we put forward an argument that individual consent can be supplemented by group ethical models. We thus conclude that while informed consent is problematic for biobank researchers, alternative ethical solutions are available. (shrink)

The mental health of young people is a growing public health concern. With socio-emotional difficulties in youth often resulting in psychiatric disorders later in life and most with mental health conditions rather stabilizing in time, it is essential to support healthy socio-emotional development. With a comprehensive definition of mental health, since emotion regulation plays a critical role in prevention, it becomes imperative to better understand how children effectively manage their emotions from an early age. Determining effective use of ER skills (...) relies on adequate measurements. Typical methods of data collection in children present consistent shortcomings. This review addresses research findings considering the suitability of the late positive potential measured through electroencephalogram as a neural indicator of ER in children and youth. There is growing evidence, as reported in this review, that indicates that the late positive potential may be a reliable neural indicator of children's cognitive reappraisal abilities more specifically. Results generally suggest that the late positive potential amplitudes are sensitive to directed reappraisal in children. However, given the scant research, questions remain regarding developmental trends, methodology, interindividual variability, reappraisal of various stimuli, and how the late positive potential may relate to more traditional measures of ER. Directions for future research are provided, which are expected to address unanswered research questions and fill literature gaps. Taken together, the findings reviewed indicate that the late positive potential is generally sensitive to directed cognitive reappraisal in children and that there is promise of establishing this neural marker as an indicator of ER. (shrink)

Previous research has demonstrated that hormones, relationship goals, and social context influence interest in the opposite sex. It has not been previously reported, however, whether having a current sexual partner also influences interest in members of the opposite sex. To test this, we obtained explicit and implicit measures of interest by measuring men’s and women’s subjective ratings and response times while they evaluated photos of opposite-sex faces. Fifty-nine men and 56 women rated 510 photos of opposite-sex faces for realism, masculinity, (...) attractiveness, or affect. We found that these subjective ratings were not influenced by partner status in either men or women. However, women who did not report having a current sexual partner spent more time evaluating the photos than women who did have partners, demonstrating greater interest in the photos. Sexual partner status did not predict men’s response times. These findings may reveal that relationship commitment in women suppresses interest in alternative partners. (shrink)

The inclusion of elite transwomen athletes in sport is controversial. The recent International Olympic Committee (IOC) (2015) guidelines allow transwomen to compete in the women’s division if (amongst other things) their testosterone is held below 10 nmol/L. This is significantly higher than that of cis-women. Science demonstrates that high testosterone and other male physiology provides a performance advantage in sport suggesting that transwomen retain some of that advantage. To determine whether the advantage is unfair necessitates an ethical analysis of the (...) principles of inclusion and fairness. Particularly important is whether the advantage held by transwomen is a tolerable or intolerable unfairness. We conclude that the advantage to transwomen afforded by the IOC guidelines is an intolerable unfairness. This does not mean transwomen should be excluded from elite sport but that the existing male/female categories in sport should be abandoned in favour of a more nuanced approach satisfying both inclusion and fairness. (shrink)

Preadolescence is an important period for the consolidation of certain arithmetic facts, and the development of problem-solving strategies. Obese subjects seem to have poorer academic performance in math than their normal-weight peers, suggesting a negative effect of obesity on math skills in critical developmental periods. To test this hypothesis, event-related potentials were collected during a delayed-verification math task using simple addition and subtraction problems in obese [above 95th body mass index percentile] and non-obese preteens with different levels of math skill; (...) thirty-one with low math skills and thirty-one with high math skills. No significant differences between weight groups were observed in task accuracy regardless of their mathematical skill level. For ERPs, electrophysiological differences were found only in the subtraction condition; participants with obesity showed an electrophysiologic pattern associated with a reduced ability to allocate attention resources regardless of their math skill level, these differences were characterized by longer P300 latency than their normal-weight peers. Moreover, the participants with obesity with high math skills displayed hypoactivity in left superior parietal lobule compared with their normal-weight peers. Additionally, obese preteens with low math skills displayed smaller arithmetic N400 amplitude than non-obese participants, reflecting difficulties in retrieving visual, semantic, and lexical information about numbers. We conclude that participants with obesity are less able than their normal-weight peers to deploy their attention regardless of their behavioral performance, which seems to have a greater effect on obese participants with low math skills because they also show problems in the retrieval of solutions from working memory, resulting in a delay in the development of mathematical skills. (shrink)

Michael Walzer is one of the most distinguished political philosophers and social critics of this century. His ideas have had great import and influence in political philosophy and political discussion, yet very few of his ideas have been incorporated explicitly into the business ethics literature. We argue that Walzer’s work provides an important conceptual canvas for business ethics scholars that has not been adequately explored. Scholars in business ethics often borrow from political theory and philosophy to generate new insights and (...) develop new substantive contributions. Many valuable theoretical resources are already used extensively—particularly Aristotle, Kant, Marx and a variety of utilitarian philosophers. Walzer offers another set of resources to bring to the conversation of what business ethics is and how business ethicists add value. This paper provides an opportunity to delve further into Walzer’s writings, particularly themes that are tied to business ethics, and to illustrate how his ideas can be extended to reshape our understanding of the field and develop new perspectives on ethical issues in commerce. (shrink)

The aim of the study was to develop a new comprehensive reading assessment battery for multi-ethnic and multilingual learners in Malaysia. Using this assessment battery, we examined the reliability, validity, and dimensionality of the factors associated with reading difficulties/disabilities in the Malay language, a highly transparent alphabetic orthography. In order to further evaluate the reading assessment battery, we compared results from the assessment battery with those obtained from the Malaysian national screening instrument. In the study, 866 Grade 1 children from (...) multi-ethnic and multilingual backgrounds from 11 government primary schools participated. The reading assessment battery comprised 13 assessments, namely, reading comprehension, spelling, listening comprehension, letter name knowledge, letter name fluency, rapid automatized naming, word reading accuracy, word reading efficiency, oral reading fluency, expressive vocabulary, receptive vocabulary, elision, and phonological memory. High reliability and validity were found for the assessments. An exploratory factor analysis yielded three main constructs: phonological-decoding, sublexical-fluency, and vocabulary-memory. Phonological-decoding was found to be the most reliable construct that distinguished between at-risk and non-at-risk children. Identifying these underlying factors will be useful for detecting children at-risk for developing reading difficulties in the Malay language. In addition, these results highlight the importance of including a range of reading and reading-related measures for the early diagnosis of reading difficulties in this highly transparent orthography. (shrink)

ABSTRACT Digital mental health interventions have emerged as a promising means of expanding access to mental healthcare. Prospective participants reporting severe symptoms or suicidal ideation are often excluded from DMHI trials and may struggle to access alternative treatments. However, evidence suggests that DMHIs are efficacious for people reporting these characteristics. We suggest that there are risks to both including and excluding people from DMHI trials, and we urge researchers to ensure that their eligibility criteria are designed in an evidence-based and (...) ethically conscious manner. We also make specific recommendations for those working in various other capacities within the academic community. (shrink)

The American Journal of Bioethics, Volume 12, Issue 1, Page 16-18, January 2012.

This paper is a contribution to the small but growing body of scholarship dedicated to a reappraisal of German occultism in the period prior to the Second World War. Moving beyond those analyses of the German occult movement which have viewed it solely in terms of its links--often tenuous--to National Socialism, this paper considers German occultism, specifically parapsychology, as a mode of cultural critique utilised by Germans from across the political spectrum. Concentrating on the experimental study of materialisation and its (...) theorisation as "supernormal biology," this paper argues for strong links, forged primarily by the biologist, philosopher, and neo-vitalist Hans Driesch (1867-1941), between parapsychology, as a way of understanding life and mind, and epistemological reforms within biology and psychology. It argues, furthermore, that for Driesch, as for a number of European scholars, parapsychology provided scientific validation of a belief in the naturalness of liberalism and pacifism. (shrink)

BackgroundWhen conducting research with Indigenous populations consent should be sought from both individual participants and the local community. We aimed to search and summarise the literature about methods for seeking consent for research with Indigenous populations.MethodsA systematic literature search was conducted for articles that describe or evaluate the process of seeking informed consent for research with Indigenous participants. Guidelines for ethical research and for seeking consent with Indigenous people are also included in our review.ResultsOf 1447 articles found 1391 were excluded (...) ; 56 were relevant and included. Articles were categorised into original research that evaluated the consent process or publications detailing the process of seeking consent and guidelines for ethical research. Guidelines were categorised into international ; national and state/regional/local guidelines. In five studies based in Australia, Canada and The United States of America the consent process with Indigenous people was objectively evaluated. In 13 other studies interpreters, voice recording, videos, pictures, flipcharts and “plain language” forms were used to assist in seeking consent but these processes were not evaluated. Some Indigenous organisations provide examples of community-designed resources for seeking consent and describe methods of community engagement, but none are evaluated. International, national and local ethical guidelines stress the importance of upholding Indigenous values but fail to specify methods for engaging communities or obtaining individual consent. In the ‘Grey literature’ concerns about the consent process are identified but no solutions are offered.ConclusionConsultation with Indigenous communities is needed to determine how consent should be sought from the community and the individual, and how to evaluate this process. (shrink)

Recent scholarship in intellectual humility (IH) has attempted to provide deeper understanding of the virtue as personality trait and its impact on an individual's thoughts, beliefs, and actions. A limitations-owning perspective of IH focuses on a proper recognition of the impact of intellectual limitations and a motivation to overcome them, placing it as the mean between intellectual arrogance and intellectual servility. We developed the Limitations-Owning Intellectual Humility Scale to assess this conception of IH with related personality constructs. In Studies 1 (...) (n= 386) and 2 (n = 296), principal factor and confirmatory factor analyses revealed a three-factor model – owning one's intellectual limitations, appropriate discomfort with intellectual limitations, and love of learning. Study 3 (n = 322) demonstrated strong test-retest reliability of the measure over 5 months, while Study 4 (n = 612) revealed limitations-owning IH correlated negatively with dogmatism, closed-mindedness, and hubristic pride and positively with openness, assertiveness, authentic pride. It also predicted openness and closed-mindedness over and above education, social desirability, and other measures of IH. The limitations-owning understanding of IH and scale allow for a more nuanced, spectrum interpretation and measurement of the virtue, which directs future study inside and outside of psychology. (shrink)

Multiple states are at risk of becoming uninhabitable due to climate change, forcing their populations to flee. While the 1951 Refugee Convention provides the gold standard of international protection, it is only applied to a limited subset of people fleeing their countries, those who suffer persecution, which most people fleeing climate change cannot establish. While many journalists and non-lawyers freely use the term “climate refugees,” governments, and courts, as well as UNHCR and many refugee experts, have excluded most climate refugees (...) from the Convention as a matter of legal interpretation. In our 2015 paper, “Unable to Return in the 1951 Refugee Convention: Stateless Refugees and Climate Change”, we sought to reopen the debate on “climate refugees” by arguing that some climate refugees qualify under the 1951 Convention as it is currently written (even if they are not persecuted): those who are stateless and are unable to return to their country of origin because climate change has rendered it uninhabitable. Our interpretation, however, has been rejected by Goodwin-Gill and McAdam (2021) and by Foster and Lambert (2019), which explicitly responds to our paper. Here, we address and respond to their arguments, and develop a new supplementary one, drawing on the principle of systemic integration, as enshrined in Article 31(3)(c) of the Vienna Convention on the Law of Treaties. (shrink)

If a person, A, branches into B and C, then it is widely held that B and C are not identical to one another. Many think that this is because B and C have contradictory properties at the same time. In this paper, I show why this explanation cannot be right. I argue that contradictory properties at times are not necessary for non-identity between descendants, and that contradictory properties at times are not sufficient for non-identity. I also argue that the (...) standard explanation cannot be salvaged by a shift to personal time. Appeals to a lack of continuity, or to the absence of unity of consciousness likewise fail. Rather, B and C are non-identical simply because A branched into B and C. Why branching should be problematic for personal identity remains a deep puzzle though I offer some tentative suggestions. (shrink)

This book is born from a desire to understand how Plato influenced and was influenced by the intellectual culture of Western Greece, the ancient Hellenic cities of Sicily and Southern Italy. In 2018, a seminar on Plato at Syracuse was organized, in which a small group of scholars discussed a new translation of the Seventh Letter and several essays on the topic. The seminar was intense but friendly, having attracted a diverse group of scholars that ranged from graduate students to (...) senior professors, hailing from at least three different continents, and representing a variety of academic specialties. We tried to create a book that would invite further study of the topic by identifying new questions to be asked while addressing enduring issues. The essays consider the historical, political, and philosophical implications of Plato’s involvement in Syracuse. They also look at the reception of his voyage among fellow philosophers, ancient and modern. Readers may come to their own conclusions, but one thing is clear: the history of philosophy was profoundly influenced by Plato’s voyages in Western Greece. The book begins with a new translation of Plato’s Seventh Letter by Jonah Radding, as well as the epitaph for Dion attributed to Plato. An introduction by editors Heather Reid and Mark Ralkowski is followed by essays from Carolina Araújo, Christos C. Evangeliou, Filippo Forcignanò, Francisco J. Gonzalez, Jill Gordon, Andrew Hull, Tony Leyh, Marina Marren, Mary R. McHugh, Robert Metcalf, Marion Theresa Schneider, Karen Sieben, and Nickolas Pappas. (shrink)

Her name was Flavia Thalassia and she came from Ephesus. She won the stadion for parthenoi at the Isolympic Sebasta Games in Naples during Domitian’s reign in the late 1st c. C...

Background Preserving persons’ dignity is integral to nursing. More research is needed to explore how a diversity of patients, particularly those that experience illness from a young age, experience dignity. Aim Describe the characteristics of dignity for persons living with serious illness. Research design Using a secondary data set of twenty audio-recorded interviews, a thematic content analysis was conducted to identify characteristics of dignity. The research team employed van Gennip et al.’s, 2013 “Model of Dignity in Illness” (1) to create (...) a codebook, which the authors utilized to independently code twenty narrative interview transcripts. Participants and research context Twenty persons living with serious illness of heart failure and/or dialysis-dependent renal failure who were admitted in an acute care hospital. Ethical considerations This study was approved on August 26, 2019, by the Colorado Multiple Institutional Review Board (COMIRB) IRB Protocol #19-1874. Findings Early-onset participants expressed markedly different dignity concerns than late-onset participants. In the individual domain, early-onset participants felt that their illness was “normal”; they did not experience the “healthy person to patient” transition described by older onset participants. In the relational domain, early-onset participants expressed that their relationships had already integrated their illness while late-onset participants felt that their illness harmed many of their relationships. In the societal domain, early-onset participants described dignity concerns related to how society impacted their ability to financially support themselves during their illness. Discussion Differences in the dignity experience of early-onset and late-onset participants are informed by Erikson’s “Model of Development” and by Aranda and Jones feminist critique of dignity in healthcare. Conclusions Persons with early-onset illness experience dignity differently. Awareness of the importance of work and financial independence to the experience of dignity for seriously ill patients may enhance persons’ dignity experience. (shrink)