Different types of consent are used to obtain human biospecimens for future research. This variation has resulted in confusion regarding what research is permitted, inadvertent constraints on future research, and research proceeding without consent. The National Institutes of Health Clinical Center's Department of Bioethics held a workshop to consider the ethical acceptability of addressing these concerns by using broad consent for future research on stored biospecimens. Multiple bioethics scholars, who have written on these issues, discussed the reasons for consent, the (...) range of consent strategies, and gaps in our understanding, and concluded with a proposal for broad initial consent coupled with oversight and, when feasible, ongoing provision of information to donors. This article describes areas of agreement and areas that need more research and dialogue. Given recent proposed changes to the Common Rule, and new guidance regarding storing and sharing data and samples, this is an important and tim.. (shrink)

Hank Greely’s target article, “Human Brain Surrogates Research: The Onrushing Ethical Dilemma” reviews the manifold scientific and ethical questions surrounding models of human brains used i...

In October 2022, I had the privilege of joining Hank Greely on the opening panel of the annual International Neuroethics Society (INS) meeting in Montréal, Tiohtiá:ke, situated on the traditional t...

In this paper I defend an account of the nature of propositional content according to which the proposition expressed by a declarative sentence is a certain type of action a speaker performs in uttering that sentence. On this view, the semantic contents of proper names turn out to be types of reference acts. By carefully individuating these types, it is possible to provide new solutions to Frege’s puzzles about names in identity- and belief-sentences.

Human brain research is moving into a dilemma. The best way to understand how the human brain works is to study living human brains in living human beings, but ethical and legal standards make it d...

In 1913 Wittgenstein raised an objection to Russell’s multiple relation theory of judgment that eventually led Russell to abandon his theory. As he put it in the Tractatus, the objection was that “the correct explanation of the form of the proposition, ‘A makes the judgement p’, must show that it is impossible for a judgement to be a piece of nonsense. (Russell’s theory does not satisfy this requirement,” (5.5422). This objection has been widely interpreted to concern type restrictions on the (...) constituents of judgment. I argue that this interpretation is mistaken and that Wittgenstein’s objection is in fact a form of the problem of the unity of the proposition. (shrink)

Propositions, the abstract, truth-bearing contents of sentences and beliefs, continue to be the focus of healthy debates in philosophy of language and metaphysics. This article is a critical survey of work on propositions since the mid-90s, with an emphasis on newer work from the past decade. Topics to be covered include a substitution puzzle about propositional designators, two recent arguments against propositions, and two new theories about the nature of propositions.

In Hanks I defend a theory of propositions that locates the source of propositional unity in acts of predication that people perform in thought and speech. On my account, these acts of predication are judgmental or assertoric in character, and they commit the speaker to things being the way they are represented to be in the act of predication. This leads to a problem about negations, disjunctions, conditionals, and other kinds of embeddings. When you assert that a is F or (...) b is G you do not assert that a is F, nor do you commit yourself to a’s being F. According to my theory, however, in uttering the disjunction you predicate F of a. What is going on? I account for these cases using the concept of cancellation. In uttering the disjunction, the act of predicating F of a is cancelled, and when an act of predication is cancelled it does not count as an assertion and does not commit the speaker to anything. But what is it for an act of predication to be cancelled? One immediate concern is that cancelled predication won’t provide a unified proposition to be the input to disjunction. In this paper I answer this and related objections by explaining and defending my concept of cancellation. (shrink)

A first-person proposition is a proposition that only a single subject can assert or believe. When I assert ‘I am on fire’ I assert a first-person proposition that only I have access to, in the sense that no one else can assert or believe this proposition. This is in contrast to third-person propositions, which can be asserted or believed by anyone.

The study aims at the systematic presentation of basic systems of scholastic epistemic logic (regardless of its original distribution into different contexts and genres). Scholastic epistemic logic can be (re)interpreted as a conservative extension of a certain non-modal base, which can be viewed as the model of epistemic agents. Its fundamental principles are: [O] if φ implies ψ and an agent knows that φ, then the agent knows that ψ; [T] if an agent knows that φ, then φ; [K] if (...) an agent knows that φ implies ψ and that φ, then the agent knows that ψ; [4] an agent who knows φ knows to know φ; [5] an agent who fails to know φ knows to fail to know φ; (or their modifications). From this point of view, scholastic epistemic logic can be construed as a confrontation of logical systems with unequal strength, ranging between that of John Wyclif, Peter of Mantua and Paul of Venice, William Heytesbury, and finally (a different theory of) Paul of Venice. These systems represent the hierarchy of epistemic agents by extending the set of their basic properties, including veridicality, inferential extendability, and introspectibility of knowledge. (shrink)

Epistemic feelings like tip-of-the-tongue experiences, feelings of knowing, and feelings of confidence tell us when a memory can be recalled and when a judgment was correct. Thus, they appear to be a form of metacognition, but a curious one: they tell us about content we cannot access, and the information is supplied by a feeling. Evaluativism is the claim that epistemic feelings are components of a distinct, primitive metacognitive mechanism that operates on its own set of inputs. These inputs are (...) heuristics that correlate with the presence of mental content that can’t be accessed directly. I will argue that evaluativism is unmotivated, unsupported, and ill-conceived. I will critique the philosophical and empirical arguments for evaluativism and conclude that there is no reason to posit a distinct mechanism to explain epistemic feelings. I will conclude, however, that epistemic feelings may constitute a nonconceptual form of metacognition, which if true is a significant claim. (shrink)

The problem of the source of necessity is the problem of explaining what makes necessary truths necessarily true. Simon Blackburn has presented a dilemma intended to show that any reductive, realist account of the source of necessity is bound to fail. Although Blackburn's dilemma faces serious problems, reflection on the form of explanations of necessities reveals that a revised dilemma succeeds in defeating any reductive account of the source of necessity. The lesson is that necessity is metaphysically primitive and irreducible.

This paper focuses on the early sixteenth-century epistemic logic developed by John Mair’s circle and discusses iterated epistemic modalities, epistemic closure and Bradwardinian semantics related to the logic of epistemic statements. These topics are addressed as part of setting up and solving epistemic sophisms based on traditional scenarios which can be traced back to fourteenth-century British epistemic logic. While the ultimate source for the debate appears to be the second chapter of William Heytesbury’s Regule solvendi sophismata, the immediate source is (...) the Italian editorial, commentarial and philosophical tradition, notably Paul of Venice and Cajetan of Thiene. (shrink)

The authors examine the scientific possibility and the legal and ethical implications of using DNA forensic technology, through partial matches to DNA from crime scenes, to turn into suspects the relatives of people whose DNA profiles are in forensic databases.

Corporate social responsibility (CSR) and its action-oriented offspring Corporate Citizenship (CC) currently trigger an intensifying debate on ethics, role and behavior of companies within civil society. For companies, CSR raises the question of what may be the "good reason(s)" for acting responsible towards its members, customers or society. In order to answer this question, we face the debate on CSR and its strategic engagement drivers on the levels of corporate culture, social innovation, and civil society. In this article, we provide (...) a conceptual framework based on the analytic distinction of legitimation and sensemaking. The conceptual framework developed in this article can serve as a basis to develop a company's CSR strategy. It provides measures and instruments to make complex CSR processes more visible and manageable. (shrink)

Peter Hanks defends a new theory about the nature of propositional content, according to which the basic bearers of representational properties are particular mental or spoken actions. He explains the unity of propositions and provides new solutions to a long list of puzzles and problems in philosophy of language.

This essay focuses on possible nonhuman applications of CRISPR/Cas9 that are likely to be widely overlooked because they are unexpected and, in some cases, perhaps even “frivolous.” We look at five uses for “CRISPR Critters”: wild de-extinction, domestic de-extinction, personal whim, art, and novel forms of disease prevention. We then discuss the current regulatory framework and its possible limitations in those contexts. We end with questions about some deeper issues raised by the increased human control over life on earth offered (...) by genome editing. (shrink)

Some of the most interesting recent work in philosophy of language and metaphysics is focused on questions about propositions, the abstract, truth-bearing contents of sentences and beliefs. The aim of this guide is to give instructors and students a road map for some significant work on propositions since the mid-1990s. This work falls roughly into two areas: challenges to the existence of propositions and theories about the nature and structure of propositions. The former includes both a widely discussed puzzle about (...) propositional designators as well as direct and indirect arguments against the existence of propositions. The latter is dominated by what is currently the central debate about the metaphysics of propositions, i.e. whether they are structured, composite entities or unstructured ontological simples. This issue has eclipsed older debates about whether propositions can be identified with sets of possible worlds or other kinds of sentence intensions. Author Recommends 1. Soames, Scott. 'Direct Reference, Propositional Attitudes, and Semantic Content.' Philosophical Topics 15 (1987): 47–87. Reprinted in Propositions and Attitudes . Eds. N. Salmon and S. Soames. Oxford: Oxford University Press, 1988. 197–239. Essential groundwork for more recent work on propositions. Soames gives a careful and exacting presentation of the case against identifying propositions with sets of possible worlds or other truth-supporting circumstances. Also contains a detailed statement of the Russellian conception of propositions on which propositions are ordered sets of objects, properties and relations. 2. King, Jeffrey. 'Designating Propositions.' The Philosophical Review 111 (2002): 341–71. Sometimes substituting a definite description for a corresponding 'that'-clause can lead to bizarre changes in truth-conditions: compare 'Bill fears that Hillary will be president' with 'Bill fears the proposition that Hillary will be president'. This puzzle about propositional designators threatens the relational analysis of propositional attitude reports, the view that 'believes' expresses a relation to the proposition designated by its 'that'-clause, and thereby poses an indirect threat to the existence of propositions. King's solution posits an ambiguity in verbs like 'fear' that embed both 'that'-clauses and definite descriptions. 3. Jubien, Michael. 'Propositions and the Objects of Thought.' Philosophical Studies 104 (2001): 47–62. A direct attack on the existence of propositions. Jubien deploys an analogue of the problem that Paul Benacerraf raised for set-theoretical reductions of numbers against metaphysical reductions of propositions. Just as numbers can be reduced to sets in many different ways, any reduction of propositions brings with it equally good variants, thus making any such reduction arbitrary and unmotivated. The only alternative is to treat propositions as abstract metaphysical primitives. As Jubien argues, however, abstract primitive entities are incapable of doing what propositions must do, i.e. represent objects and states of affairs on their own, without the input of thinking subjects. The upshot is the propositions cannot be reduced and they cannot be primitive, and so they must not exist. 4. Hanks, Peter. 'How Wittgenstein Defeated Russell's Multiple Relation Theory of Judgment.' Synthese 154 (2007): 121–46. Scepticism about propositions has recently led some philosophers, Jubien included, to resuscitate Russell's multiple relation theory of judgment, the idea that judgment is a many-place relation to objects, properties and relations. This paper explains why Russell himself abandoned that theory, and why the theory is still refuted by an objection due to Wittgenstein. 5. Hofweber, Thomas. 'Inexpressible Properties and Propositions.' Oxford Studies in Metaphysics . 2 vols. Ed. D. Zimmerman. Oxford: Oxford University Press, 2006. 155–206. An indirect attack on the existence of propositions. Hofweber argues that sentences like 'Bill believes something that Hillary asserted' do not commit us to the existence of propositions. His view is that propositional quantification is an instance of what he calls 'internal' or 'inferential role' quantification, a kind of quantification that carries no ontological implications. 6. Schiffer, Stephen. The Things We Mean . Oxford: Oxford University Press, 2003. esp. chs 1–2. Schiffer defends his theory of pleonastic propositions, on which propositions are unstructured, have no parts, and are very finely grained. 7. Bealer, George. 'Propositions.' Mind 107 (1998): 1–32. Bealer defends his algebraic theory of propositions, which, like Schiffer's pleonastic account, treats propositions as unstructured metaphysical simples. 8. King, Jeffrey. The Nature of and Structure of Content . Oxford: Oxford University Press, 2007. The best developed current theory of the structure in structured propositions. King identifies propositions with certain kinds of facts in which objects, properties and relations are bound together by amalgams of syntactic and semantic relations. 9. Hanks, Peter. 'Recent Work on Propositions.' Philosophy Compass 4 (2009): 1–18. A survey of work on propositions since the mid-1990s that complements this teaching and learning guide. Contains responses to Jubien's and Hofweber's arguments against propositions and critical discussions of Schiffer's pleonastic propositions and King's theory of propositional structure. Online Resources 1. http://plato.stanford.edu/entries/propositions/ Propositions (Matthew McGrath) 2. http://plato.stanford.edu/entries/propositions-structured/ Structured Propositions (Jeffrey King) 3. http://plato.stanford.edu/entries/propositions-singular/ Singular Propositions (Greg Fitch) Sample Partial Syllabus The following partial syllabus can be used as a unit on recent work on propositions in graduate level courses in philosophy of language or metaphysics. Week 1: A Substitution Puzzle About Propositional Designators King, Jeffrey. 'Designating Propositions'. Moltmann, Friederike. 'Propositional Attitudes Without Propositions.' Synthese 135 (2003): 77–118. Week 2: The Benacerraf Problem and Propositional Representation Benacerraf, Paul. 'What Numbers Could Not Be.' Philosophical Review 74 (1965): 47–73. Jubien, Michael. 'Propositions and the Objects of Thought.' Week 3: Propositional Quantification Hofweber, Thomas. 'Inexpressible Properties and Propositions'. Hofweber, Thomas. 'A Puzzle about Ontology.' Noûs 39 (2005): 256–83. Week 4: Schiffer on Pleonastic Propositions Schiffer, Stephen. 'Language-Created Language-Independent Entities.' Philosophical Topics 24 (1996): 149–67. Schiffer, Stephen. The Things We Mean , chs 1–2. Week 5: King on Structured Propositions King, Jeffrey. 'Structured Propositions and Complex Predicates.' Noûs , 29 (1995): 516–35. King, Jeffrey. The Nature and Structure of Content , chs 1–3. Focus Questions 1. Why does identifying propositions with sentence intensions, e.g. sets of possible worlds, 'require the attitudes to have a particular sort of closure under logical consequence, which they clearly don't have' (Mark Richard)? 2. How does the difference between (a) and (b) pose a threat to the existence of propositions? (a) Bill fears that Hillary will be president. (b) Bill fears the proposition that Hillary will be president. 3. What is the Benacerraf problem for metaphysical reductions of propositions? 4. Why must a proposition represent 'on its own cuff' (Michael Jubien)? Why is this a problem for the view that propositions are primitive abstract entities? 5. What does it mean to say that propositions are structured ? Give two different accounts of what propositional structure might be. (shrink)

Much of the legal and social interest in new neuroimaging techniques stems from the belief that they can deliver on the materialist understanding of the relationship between the brain and the mind. This article looks at predictions about the future both of scientific advances and of social reactions to those predictions. It looks at the likely technical limits on neuroscience-based mindreading, then at the likely limits in how the law might use such technologies. It describes three kinds of technical barriers (...) to detailed and useful mindreading: the likely impossibility of making a complete and accurate model of a human brain in light of its incredible complexity, the problems of interpersonal and intrapersonal plasticity, and the problem of trying to read, now, someone's past mental state. The potential changes to the operation of the law, through the use of mindreading as evidence of pain, deception, or bias, among other things, could be extremely important. (shrink)

The conference where this article was originally presented solicited recommendations for the “right questions” to ask regarding education and technology. The author of this article suggests that we already know what the right questions are for illuminating technology and its social meaning. What the author wants to know is why those questions in fact are not being asked more widely—why is widespread disinclination to enter explicit deliberation on the proper place of technology so resilient? Langdon Winner uses the term “technological (...) somnambulism” to describe the predominant stance toward technology in our culture, that “we so willingly sleepwalk through the process of reconstituting the conditions of human existence” via the adoption of new technologies. The basic institutional and ideological forces shaping the development and use of technology are not mysterious. But, scrutiny of those forces remains limited to a relative handful of academics and activists. How can technological somnambulism be countered? (shrink)

All too often when philosophers talk and write about sentences they have in mind only indicative sentences, that is, sentences that are true or false and that are normally used in the performance of assertions. When interrogative sentences are mentioned at all it is usually either in the form of a gesture toward some extension of the account of indicatives or an acknowledgment of the limitations of such an account. For example, in the final two sentences of his influential paper (...) “Truth and Meaning” (1967) Donald Davidson remarks. (shrink)

Reality testing is the process by which we distinguish our own perceptual states from imagination or episodic memory. I argue that reality testing is a metacognitive process. Since reality testing is also accomplished by creatures who lack mental state concepts, it follows that reality testing is a nonconceptual metacognitive process. I also provide prima facie evidence that reality testing is a necessary condition for prototypical cognitive states like belief. It follows that metacognition is phylogenetically and logically prior to cognition in (...) many cases. (shrink)

(2013). What are the primary bearers of truth? Canadian Journal of Philosophy: Vol. 43, Essays on the Nature of Propositions, pp. 558-574.

O texto parte das considerações que Schopenhauer faz acerca do princípio de razão suficiente do agir na sua dissertação Sobre a quadrúplice raiz do princípio de razão suficiente e da negação da Vontade de vida nos §68-70 de O mundo como vontade e como representação; e como a conduta relacionada a este conceito pode ser observada ao longo da história, seja no cristianismo ou nas religiões indianas, mostrando como é possível chegar à tal conhecimento. Em seguida, aliado ao texto kantiano (...) sobre as grandezas negativas, mostro a inversão que Schopenhauer faz dos sinais do que é considerado positivo ou negativo, ou seja, ser e nada, devido a uma troca de perspectiva em consequência da chamada “viragem da vontade”. (shrink)